aChair and Department of Medical Chemistry and Laboratory Medicine

bDepartment of Hypertensiology, Angiology, and Internal Diseases

cDepartment of Pharmacology

dDepartment of Cancer Immunology, Poznan University of Medical Sciences

eGene Therapy Unit, Department of Diagnostics and Cancer Immunology, Greater Poland Cancer Center, Poznan, Poland

Correspondence to Magdalena Budzyń, Chair and Department of Medical Chemistry and Laboratory Medicine, Poznan University of Medical Sciences, 8 Rokietnicka Street, 60-806 Poznan, Poland. Tel: +48 504 082 380; e-mail: [email protected]

Abbreviations: ABPM, ambulatory blood pressure monitoring; ACEIs, angiotensin-converting enzyme inhibitors; Ang II, angiotensin II; ARBs, angiotensin receptor blockers; BP, blood pressure; CCBs, Calcium channel blockers; CECs, circulating endothelial cells; EDTA, ethylenediaminetetraacetic acid; eGFR, estimated glomerular filtration rate; HGB, hemoglobin; HP, hypertensive patients; IL-6, interlukine 6; LPS, lipopolysaccharides; LYMH, lymphocytes; Mac-1, macrophage-1 antigen; MFI, mean fluorescence intensity; MH, mild hypertension; MONO, monocytes; MRAs, mineralocorticoid receptor antagonists; NEUT, neutrophils; NK-κB, nuclear factor kappa-light-chain-enhancer of activated B cells; NLR, neutrophil-to-lymphocyte ratio; PBMCs, peripheral blood mononuclear cells; PLR, platelet/lymphocytes ratio; PLT, blood platelets; RBC, red blood cells; RH, resistant hypertension; TIA, transient ischemic attack; TLR4, toll like receptor 4; TNFα, tumor necrosis factor alpha; WBC, white blood cells

Received 31 August, 2023

Accepted 26 October, 2023

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