aNova Southeastern University Barry and Judy Silverman College of Pharmacy, Palm Beach Campus, North Military Trial Palm Beach Gardens

bNova Southeastern University Barry and Judy Silverman College of Pharmacy, Fort Lauderdale-Davie Campus, 3200 S University Drive, Davie, Florida, USA

Correspondence to Genevieve Hale, PharmD, BCPS, BCCP, CPh, Associate Professor, Department of Pharmacy Practice, Nova Southeastern University Barry and Judy Silverman College of Pharmacy, 11501 North Military Trial Palm Beach Gardens, FL 33410, USA. Tel: +1 561 805 2218; e-mail: [email protected]

Abbreviation: ACEI, angiotensin-converting enzyme inhibitors; ALLHAT, Antihypertensive and Lipid Lowering Treatment to Prevent Heart Attack; ARB, angiotensin II receptor blockers; CCB, calcium channel blockers; HCTZ, hydrochlorothiazide; LEGEND, Large-Scale Evidence Generation and Evaluation in a Network of Databases; MACE, major adverse cardiovascular events; NHANES, National Health and Nutrition Examination Survey; PAI-1, plasminogen activator inhibitor-1; RAAS, renin–angiotensin–aldosterone system; SHEP, Systolic Hypertension in the Elderly Program

Received 8 August, 2023

Revised 13 October, 2023

Accepted 7 November, 2023

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