Gilfillan M, Bhandari A, Bhandari V. Diagnosis and management of bronchopulmonary dysplasia. BMJ. 2021;375:n1974.

Article  PubMed  Google Scholar 

Stoll BJ, Hansen NI, Bell EF, Shankaran S, Laptook AR, Walsh MC, et al. Neonatal outcomes of extremely preterm infants from the NICHD Neonatal Research Network. Pediatrics. 2010;126:443–56.

Article  PubMed  Google Scholar 

Bell EF, Hintz SR, Hansen NI, Bann CM, Wyckoff MH, De Mauro SB, et al. Mortality, In-Hospital Morbidity, Care Practices, and 2-Year Outcomes for Extremely Preterm Infants in the US, 2013–2018. JAMA. 2022;327:248–63.

Article  PubMed  Google Scholar 

Savani RC. Modulators of inflammation in bronchopulmonary dysplasia. Semin Perinatol. 2018;42:459–70.

Article  PubMed  PubMed Central  Google Scholar 

Álvarez-Fuente M, Moreno L, Mitchell JA, Reiss IK, Lopez P, Elorza D, et al. Preventing bronchopulmonary dysplasia: new tools for an old challenge. Pediatr Res. 2019;85:432–41.

Article  PubMed  Google Scholar 

Rudloff I, Cho SX, Bui CB, McLean C, Veldman A, Berger PJ, et al. Refining anti-inflammatory therapy strategies for bronchopulmonary dysplasia. J Cell Mol Med. 2017;21:1128–38.

Article  CAS  PubMed  Google Scholar 

Dinarello CA. Overview of the IL-1 family in innate inflammation and acquired immunity. Immunol Rev. 2018;281:8–27.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Garlanda C, Dinarello CA, Mantovani A. The interleukin-1 family: back to the future. Immunity. 2013;39:1003–18.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sims JE, March CJ, Cosman D, Widmer MB, MacDonald HR, McMahan CJ, et al. cDNA expression cloning of the IL-1 receptor, a member of the immunoglobulin superfamily. Science. 1988;241:585–9.

Article  CAS  PubMed  Google Scholar 

Sims JE, Smith DE. The IL-1 family: regulators of immunity. Nat Rev Immunol. 2010;10:89–102.

Article  CAS  PubMed  Google Scholar 

Fritzsching B, Zhou-Suckow Z, Trojanek JB, Schubert SC, Schatterny J, Hirtz S, et al. Hypoxic epithelial necrosis triggers neutrophilic inflammation via IL-1 receptor signaling in cystic fibrosis lung disease. Am J Respir Crit Care Med. 2015;191:902–13.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Borthwick LA. The IL-1 cytokine family and its role in inflammation and fibrosis in the lung. Semin Immunopathol. 2016;38:517–34.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Omer M, Melo AM, Kelly L, Mac Dermott EJ, Leahy TR, Killeen O, et al. Emerging role of the NLRP3 inflammasome and interleukin-1β in Neonates. Neonatology. 2020;117:545–54.

Article  CAS  PubMed  Google Scholar 

Yoon BH, Romero R, Jun JK, Park KH, Park JD, Ghezzi F, et al. Amniotic fluid cytokines (interleukin-6, tumor necrosis factor-alpha, interleukin-1 beta, and interleukin-8) and the risk for the development of bronchopulmonary dysplasia. Am J Obstet Gynecol. 1997;177:825–30.

Article  CAS  PubMed  Google Scholar 

Kazzi SN, Romero R, McLaughlin K, Ager J, Janisse J. Serial changes in levels of IL-6 and IL-1beta in premature infants at risk for bronchopulmonary dysplasia. Pediatr Pulmonol. 2001;31:220–6.

Article  CAS  PubMed  Google Scholar 

Ambalavanan N, Carlo WA, D’Angio CT, McDonald SA, Das A, Schendel D, et al. Cytokines associated with bronchopulmonary dysplasia or death in extremely low birth weight infants. Pediatrics. 2009;123:1132–41.

Article  PubMed  Google Scholar 

Mao X, Qiu J, Zhao L, Xu J, Yin J, Yang Y, et al. Vitamin D and IL-10 deficiency in preterm neonates with bronchopulmonary dysplasia. Front Pediatr. 2018;6:246.

Article  PubMed  PubMed Central  Google Scholar 

Zhang Z, Wu W, Hou L, Jiang J, Wan W, Li Z. Cytokines and exhaled nitric oxide are risk factors in preterm infants for bronchopulmonary dysplasia. Biomed Res Int. 2021;2021:6648208.

Article  PubMed  PubMed Central  Google Scholar 

Butler B, De Dios R, Nguyen L, McKenna S, Ghosh S, Wright CJ. Developmentally regulated innate immune NFκB signaling mediates IL-1α expression in the perinatal murine lung. Front Immunol. 2019;10:1555.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Eldredge LC, Creasy RS, Presnell S, Debley JS, Juul SE, Mayock DE, et al. Infants with evolving bronchopulmonary dysplasia demonstrate monocyte-specific expression of IL-1 in tracheal aspirates. Am J Physiol Lung Cell Mol Physiol. 2019;317:L49–l56.

Article  CAS  PubMed  Google Scholar 

Nold MF, Mangan NE, Rudloff I, Cho SX, Shariatian N, Samarasinghe TD, et al. Interleukin-1 receptor antagonist prevents murine bronchopulmonary dysplasia induced by perinatal inflammation and hyperoxia. Proc Natl Acad Sci USA. 2013;110:14384–9.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gupta GK, Cole CH, Abbasi S, Demissie S, Njinimbam C, Nielsen HC, et al. Effects of early inhaled beclomethasone therapy on tracheal aspirate inflammatory mediators IL-8 and IL-1ra in ventilated preterm infants at risk for bronchopulmonary dysplasia. Pediatr Pulmonol. 2000;30:275–81.

Article  CAS  PubMed  Google Scholar 

Kakkera DK, Siddiq MM, Parton LA. Interleukin-1 balance in the lungs of preterm infants who develop bronchopulmonary dysplasia. Biol Neonate. 2005;87:82–90.

Article  CAS  PubMed  Google Scholar 

Jensen EA, Dysart K, Gantz MG, McDonald S, Bamat NA, Keszler M, et al. The diagnosis of bronchopulmonary dysplasia in very preterm infants. an evidence-based approach. Am J Respir Crit Care Med. 2019;200:751–9.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Davis P, Turner-Gomes S, Cunningham K, Way C, Roberts R, Schmidt B. Precision and accuracy of clinical and radiological signs in premature infants at risk of patent ductus arteriosus. Arch Pediatr Adolesc Med. 1995;149:1136–41.

Article  CAS  PubMed  Google Scholar 

Dani C, Bertini G, Reali MF, Murru P, Fabris C, Vangi V, et al. Prophylaxis of patent ductus arteriosus with ibuprofen in preterm infants. Acta Paediatr. 2000;89:1369–74.

Article  CAS  PubMed  Google Scholar 

Subspecialty Group of Neonatology, the Society of Pediatric, Chinese Medical Association; Professional Committee of Infectious Diseases, Neonatology Society, Chinese Medical Doctor Association. Expert consensus on the diagnosis and management of neonatal sepsis (version 2019). Zhonghua Er Ke Za Zhi. 2019;57:252–7.

Willet KE, Kramer BW, Kallapur SG, Ikegami M, Newnham JP, Moss TJ, et al. Intra-amniotic injection of IL-1 induces inflammation and maturation in fetal sheep lung. Am J Physiol Lung Cell Mol Physiol. 2002;282:L411–420.

Article  CAS  PubMed  Google Scholar 

Sosenko IR, Kallapur SG, Nitsos I, Moss TJ, Newnham JP, Ikegami M, et al. IL-1 alpha causes lung inflammation and maturation by direct effects on preterm fetal lamb lungs. Pediatr Res. 2006;60:294–8.

Article  CAS  PubMed  Google Scholar 

Rider P, Carmi Y, Voronov E, Apte RN. Interleukin-1α. Semin Immunol. 2013;25:430–8.

Article  CAS  PubMed  Google Scholar 

Osei ET, Noordhoek JA, Hackett TL, Spanjer AI, Postma DS, Timens W, et al. Interleukin-1α drives the dysfunctional cross-talk of the airway epithelium and lung fibroblasts in COPD. Eur Respir J. 2016;48:359–69.

Article  CAS  PubMed