Using aspirin to prevent and treat cancer

Algra AM, Rothwell PM (2012) Effects of regular aspirin on long-term cancer incidence and metastasis: a systematic comparison of evidence from observational studies versus randomised trials. Lancet Oncol 13:518–527

Article  CAS  PubMed  Google Scholar 

Angiolillo DJ, Bhatt DL, Lanza F, Cryer B, Dong JF, Jeske W, Zimmerman RR, Von Chong E, Prats J, Deliargyris EN, Marathi U (2019) Pharmacokinetic/pharmacodynamic assessment of a novel, pharmaceutical lipid-aspirin complex: results of a randomized, crossover, bioequivalence study. J Thromb Thrombolysis 48:554–562

Article  CAS  PubMed  PubMed Central  Google Scholar 

Antithrombotic Trialists C, Baigent C, Blackwell L, Collins R, Emberson J, Godwin J, Peto R, Buring J, Hennekens C, Kearney P, Meade T, Patrono C, Roncaglioni MC, Zanchetti A (2009) Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomised trials. Lancet 373:1849–1860

Article  Google Scholar 

Bar D, Lavie O, Stein N, Feferkorn I, Shai A (2016) The effect of metabolic comorbidities and commonly used drugs on the prognosis of patients with ovarian cancer. Eur J Obstet Gynecol Reprod Biol 207:227–231

Article  CAS  PubMed  Google Scholar 

Battistoni A, Mastromarino V, Volpe M (2015) Reducing cardiovascular and cancer risk: how to address global primary prevention in clinical practice. Clin Cardiol 38:387–394

Article  PubMed  PubMed Central  Google Scholar 

Bhatt DL, Grosser T, Dong JF, Logan D, Jeske W, Angiolillo DJ, Frelinger AL 3rd, Lei L, Liang J, Moore JE, Cryer B, Marathi U (2017) Enteric coating and aspirin nonresponsiveness in patients with type 2 diabetes mellitus. J Am Coll Cardiol 69:603–612

Article  CAS  PubMed  Google Scholar 

Burn J, Gerdes AM, Macrae F, Mecklin JP, Moeslein G, Olschwang S, Eccles D, Evans DG, Maher ER, Bertario L, Bisgaard ML, Dunlop MG, Ho JW, Hodgson SV, Lindblom A, Lubinski J, Morrison PJ, Murday V, Ramesar R, Side L, Scott RJ, Thomas HJ, Vasen HF, Barker G, Crawford G, Elliott F, Movahedi M, Pylvanainen K, Wijnen JT, Fodde R, Lynch HT, Mathers JC, Bishop DT, Investigators C (2011) Long-term effect of aspirin on cancer risk in carriers of hereditary colorectal cancer: an analysis from the CAPP2 randomised controlled trial. Lancet 378:2081–2087

Article  PubMed  PubMed Central  Google Scholar 

Cha YI, Dubois RN (2007) NSAIDs and cancer prevention: targets downstream of COX-2. Annu Rev Med 58:239–252

Article  CAS  PubMed  Google Scholar 

Chan AT, Giovannucci EL, Meyerhardt JA, Schernhammer ES, Curhan GC, Fuchs CS (2005) Long-term use of aspirin and nonsteroidal anti-inflammatory drugs and risk of colorectal cancer. JAMA 294:914–923

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chan AT, Manson JE, Feskanich D, Stampfer MJ, Colditz GA, Fuchs CS (2007a) Long-term aspirin use and mortality in women. Arch Intern Med 167:562–572

Article  PubMed  Google Scholar 

Chan AT, Ogino S, Fuchs CS (2007b) Aspirin and the risk of colorectal cancer in relation to the expression of COX-2. N Engl J Med 356:2131–2142

Article  CAS  PubMed  Google Scholar 

Chen WY, Holmes MD (2017) Role of Aspirin in Breast Cancer Survival. Curr Oncol Rep 19:48

Article  PubMed  Google Scholar 

Chubak, J., Kamineni, A., Buist, D. S. M., Anderson, M. L. & Whitlock, E. P. 2015. Aspirin Use for the Prevention of Colorectal Cancer: An Updated Systematic Evidence Review for the U.S. Preventive Services Task Force. Rockville (MD).

Chulada PC, Loftin CD, Winn VD, Young DA, Tiano HF, Eling TE, Langenbach R (1996) Relative activities of retrovirally expressed murine prostaglandin synthase-1 and -2 depend on source of arachidonic acid. Arch Biochem Biophys 330:301–313

Article  CAS  PubMed  Google Scholar 

Clapper ML, Cooper HS, Chang WC (2007) Dextran sulfate sodium-induced colitis-associated neoplasia: a promising model for the development of chemopreventive interventions. Acta Pharmacol Sin 28:1450–1459

Article  CAS  PubMed  Google Scholar 

Contursi A, Sacco A, Grande R, Dovizio M, Patrignani P (2017) Platelets as crucial partners for tumor metastasis: from mechanistic aspects to pharmacological targeting. Cell Mol Life Sci 74:3491–3507

Article  PubMed  Google Scholar 

Cook NR, Lee IM, Gaziano JM, Gordon D, Ridker PM, MansonHennekensBuring JECHJE (2005) Low-dose aspirin in the primary prevention of cancer: the Women’s Health Study: a randomized controlled trial. JAMA 294:47–55

Article  CAS  PubMed  Google Scholar 

Coyle C, Cafferty FH, Rowley S, Mackenzie M, Berkman L, Gupta S, Pramesh CS, Gilbert D, Kynaston H, Cameron D, Wilson RH, Ring A, Langley RE, Add-Aspirin I (2016) ADD-ASPIRIN: A phase III, double-blind, placebo controlled, randomised trial assessing the effects of aspirin on disease recurrence and survival after primary therapy in common non-metastatic solid tumours. Contemp Clin Trials 51:56–64

Article  PubMed  PubMed Central  Google Scholar 

Davis JS, Kanikarla-Marie P, Gagea M, Yu PL, Fang D, Sebastian M, Yang P, Hawk E, Dashwood R, Lichtenberger LM, Menter D, Kopetz S (2020) Sulindac plus a phospholipid is effective for polyp reduction and safer than sulindac alone in a mouse model of colorectal cancer development. BMC Cancer 20:871

Article  CAS  PubMed  PubMed Central  Google Scholar 

Drew DA, Chan AT (2021) Aspirin in the prevention of colorectal neoplasia. Annu Rev Med 72:415–430

Article  CAS  PubMed  Google Scholar 

Elwood PC, Morgan G, Delon C, Protty M, Galante J, Pickering J, Watkins J, Weightman A, Morris D (2021) Aspirin and cancer survival: a systematic review and meta-analyses of 118 observational studies of aspirin and 18 cancers. Ecancermedicalscience 15:1258

Article  PubMed  PubMed Central  Google Scholar 

Elwood PC, Morgan G, Pickering JE, Galante J, Weightman AL, Morris D, Kelson M, Dolwani S (2016) Aspirin in the treatment of cancer: reductions in metastatic spread and in mortality: a systematic review and meta-analyses of published studies. PLoS ONE 11:e0152402

Article  PubMed  PubMed Central  Google Scholar 

Elwood PC, Pickering JE, Morgan G, Galante J, Weightman AL, Morris D, Longley M, Mason M, Adams R, Dolwani S, Chia WKJ, Lanas A (2018) Systematic review update of observational studies further supports aspirin role in cancer treatment: Time to share evidence and decision-making with patients? PLoS ONE 13:e0203957

Article  PubMed  PubMed Central  Google Scholar 

Gasic GJ, Gasic TB, Murphy S (1972) Anti-metastatic effect of aspirin. Lancet 2:932–933

Article  CAS  PubMed  Google Scholar 

Giardiello FM, Hamilton SR, Krush AJ, Piantadosi S, Hylind LM, Celano P, Booker SV, Robinson CR, Offerhaus GJ (1993) Treatment of colonic and rectal adenomas with sulindac in familial adenomatous polyposis. N Engl J Med 328:1313–1316

Article  CAS  PubMed  Google Scholar 

Gibbons DC, Sinha A, Phillips RK, Clark SK (2011) Colorectal cancer: no longer the issue in familial adenomatous polyposis? Fam Cancer 10:11–20

Article  PubMed  Google Scholar 

Guirguis-Blake JM, Evans CV, Perdue LA, Bean SI, Senger CA (2022) Aspirin use to prevent cardiovascular disease and colorectal cancer: updated evidence report and systematic review for the us preventive services task force. JAMA 327:1585–1597

Article  PubMed  Google Scholar 

Guo H, Liu J, Ben Q, Qu Y, Li M, Wang Y, Chen W, Zhang J (2016) The aspirin-induced long non-coding RNA OLA1P2 blocks phosphorylated STAT3 homodimer formation. Genome Biol 17:24

Article  PubMed  PubMed Central  Google Scholar 

Guo J, Zhu Y, Yu L, Li Y, Guo J, Cai J, Liu L, Wang Z (2021) Aspirin inhibits tumor progression and enhances cisplatin sensitivity in epithelial ovarian cancer. PeerJ 9:e11591

Article  PubMed  PubMed Central  Google Scholar 

Haemmerle M, Stone RL, Menter DG, Afshar-Kharghan V, Sood AK (2018) The platelet lifeline to cancer: challenges and opportunities. Cancer Cell 33:965–983

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hallak A, Alon-BARON L, Shamir R, Moshkowitz M, Bulvik B, Brazowski E, Halpern Z, Arber N (2003) Rofecoxib reduces polyp recurrence in familial polyposis. Dig Dis Sci 48:1998–2002

Article  CAS  PubMed  Google Scholar 

Hurwitz LM, Pinsky PF, Huang WY, Freedman ND, Trabert B (2020) Aspirin use and ovarian cancer risk using extended follow-up of the PLCO Cancer Screening Trial. Gynecol Oncol 159:522–526

Article  CAS  PubMed  PubMed Central  Google Scholar 

Jacobs EJ, Thun MJ, Bain EB, Rodriguez C, Henley SJ, Calle EE (2007) A large cohort study of long-term daily use of adult-strength aspirin and cancer incidence. J Natl Cancer Inst 99:608–615

Article  CAS  PubMed  Google Scholar 

Joharatnam-Hogan N, Cafferty F, Hubner R, Swinson D, Sothi S, Gupta K, Falk S, Patel K, Warner N, Kunene V, Rowley S, Khabra K, Underwood T, Jankowski J, Bridgewater J, Crossley A, Henson V, Berkman L, Gilbert D, Kynaston H, Ring A, Cameron D, Din F, Graham J, Iveson T, Adams R, Thomas A, Wilson R, Pramesh CS, Langley R, Add-Aspirin Trial Management G (2019) Aspirin as an adjuvant treatment for cancer: feasibility results from the Add-Aspirin randomised trial. Lancet Gastroenterol Hepatol 4:854–862

Article  PubMed  Google Scholar 

Kashyap P, Farrugia G (2010) Diabetic gastroparesis: what we have learned and had to unlearn in the past 5 years. Gut 59:1716–1726

Article  CAS  PubMed 

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