Roth GA, Mensah GA, Johnson CO, Addolorato G, Ammirati E, Baddour LM, et al. Global burden of cardiovascular diseases and risk factors, 1990–2019: update from the GBD 2019 study. J Am Coll Cardiol. 2020;76:2982–3021. https://doi.org/10.1016/j.jacc.2020.11.010.
Article PubMed PubMed Central Google Scholar
Mensah GA, Fuster V, Murray CJL, Roth GA, Global Burden of Cardiovascular Diseases and Risks Collaborators. Global burden of cardiovascular diseases and risks, 1990–2022. J Am Coll Cardiol. 2023;82:2350–473. https://doi.org/10.1016/j.jacc.2023.11.007.
Article PubMed PubMed Central Google Scholar
Zhao D, Liu J, Wang M, Zhang X, Zhou M. Epidemiology of cardiovascular disease in China: current features and implications. Nat Rev Cardiol. 2019;16:203–12. https://doi.org/10.1038/s41569-018-0119-4.
Leong DP, Joseph PG, McKee M, Anand SS, Teo KK, et al. Reducing the global burden of cardiovascular disease, Part 2: prevention and treatment of cardiovascular disease. Circ Res. 2017;121:695–710. https://doi.org/10.1161/CIRCRESAHA.117.311849.
Article CAS PubMed Google Scholar
van Daalen KR, Zhang D, Kaptoge S, Paige E, Di Angelantonio E, Pennells L. Risk estimation for the primary prevention of cardiovascular disease: considerations for appropriate risk prediction model selection. Lancet Glob Health. 2024;12:e1343–58. https://doi.org/10.1016/S2214-109X(24)00210-9.
Article PubMed PubMed Central Google Scholar
Yusuf S, Joseph P, Rangarajan S, Islam S, Mente A, et al. Modifiable risk factors, cardiovascular disease, and mortality in 155 722 individuals from 21 high-income, middle-income, and low-income countries (PURE): a prospective cohort study. Lancet. 2020;395:795–808. https://doi.org/10.1016/S0140-6736(19)32008-2.
Louie JZ, Shiffman D, McPhaul MJ, Melander O. Insulin resistance probability score and incident cardiovascular disease. J Intern Med. 2023;294:531–5. https://doi.org/10.1111/joim.13687.
Article CAS PubMed Google Scholar
Powell-Wiley TM, Poirier P, Burke LE, Després JP, Gordon-Larsen P, Lavie CJ, et al. Obesity and cardiovascular disease: a scientific statement from the American Heart Association. Circulation. 2021;143:e984–1010. https://doi.org/10.1161/CIR.0000000000000973.
Article PubMed PubMed Central Google Scholar
Reaven GM. Insulin resistance: the link between obesity and cardiovascular disease. Med Clin North Am. 2011;95:875–92. https://doi.org/10.1016/j.mcna.2011.06.002.
Article CAS PubMed Google Scholar
DeFronzo RA, Tobin JD, Andres R. Glucose clamp technique: a method for quantifying insulin secretion and resistance. Am J Physiol. 1979;237(3):E214. https://doi.org/10.1152/ajpendo.1979.237.3.E214.
Article CAS PubMed Google Scholar
Salmón-Gómez L, Catalán V, Frühbeck G, Gómez-Ambrosi J. Relevance of body composition in phenotyping the obesities. Rev Endocr Metab Disord. 2023;24:809–23. https://doi.org/10.1007/s11154-023-09796-3.
Article PubMed PubMed Central Google Scholar
Muniyappa R, Lee S, Chen H, Quon MJ. Current approaches for assessing insulin sensitivity and resistance in vivo: advantages, limitations, and appropriate usage. Am J Physiol Endocrinol Metab. 2008;294:E15-26. https://doi.org/10.1152/ajpendo.00645.2007.
Article CAS PubMed Google Scholar
Lee SB, Kim MK, Kang S, Park K, Kim JH, Baik SJ, et al. Triglyceride glucose index is superior to the homeostasis model assessment of insulin resistance for predicting nonalcoholic fatty liver disease in Korean adults. Endocrinol Metab. 2019;34:179–86. https://doi.org/10.3803/EnM.2019.34.2.179.
Wang L, Ding H, Deng Y, Huang J, Lao X, Wong MCS. Associations of obesity indices change with cardiovascular outcomes: a dose-response meta-analysis. Int J Obes (Lond). 2024;48:635–45. https://doi.org/10.1038/s41366-024-01485-8.
Thomas DM, Bredlau C, Bosy-Westphal A, Mueller M, Shen W, Gallagher D, et al. Relationships between body roundness with body fat and visceral adipose tissue emerging from a new geometrical model. Obesity. 2013;21:2264–71. https://doi.org/10.1002/oby.20408.
Krakauer NY, Krakauer JC. A new body shape index predicts mortality hazard independently of body mass index. PLoS ONE. 2012;7:e39504. https://doi.org/10.1371/journal.pone.0039504.
Article CAS PubMed PubMed Central Google Scholar
Park Y, Kim NH, Kwon TY, Kim SG. A novel adiposity index as an integrated predictor of cardiometabolic disease morbidity and mortality. Sci Rep. 2018;8:16753. https://doi.org/10.1038/s41598-018-35073-4.
Article CAS PubMed PubMed Central Google Scholar
Xia MF, Chen Y, Lin HD, Ma H, Li XM, Aleteng Q, et al. A indicator of visceral adipose dysfunction to evaluate metabolic health in adult Chinese. Sci Rep. 2016;6:38214. https://doi.org/10.1038/srep38214.
Article CAS PubMed PubMed Central Google Scholar
Liu M, Pei J, Zeng C, Xin Y, Tang P, Hu X. Association and predictive value of the triglyceride glucose-weight adjusted waist index for cardiovascular outcomes in patients with type 2 diabetes. Sci Rep. 2025;15:24573. https://doi.org/10.1038/s41598-025-08580-4.
Article CAS PubMed PubMed Central Google Scholar
Lin H, Jia X, Yin Y, Li M, Zheng R, Xu Y, et al. Association of body roundness index with cardiovascular disease and all-cause mortality among Chinese adults. Diabetes Obes Metab. 2025;27:2698–707. https://doi.org/10.1111/dom.16272.
Chung W, Park JH, Chung HS, Yu JM, Moon S, Kim DS. The association between Z-score of log-transformed a body shape index and cardiovascular disease in Korea. Diabetes Metab J. 2019;43:675–82. https://doi.org/10.4093/dmj.2018.0169.
Article PubMed PubMed Central Google Scholar
Ren Y, Hu Q, Li Z, Zhang X, Yang L, Kong L. Dose-response association between Chinese visceral adiposity index and cardiovascular disease: a national prospective cohort study. Front Endocrinol (Lausanne). 2024;15:1284144. https://doi.org/10.3389/fendo.2024.1284144.
Tu W, Xu R, Wang D, Luo N, Wu M, Zhou Y, et al. Triglyceride-glucose index and its related factors may be predictors for cardiovascular disease among Chinese postmenopausal women: a 12-year cohort study. Lipids Health Dis. 2025;24:218. https://doi.org/10.1186/s12944-025-02643-1.
Article CAS PubMed PubMed Central Google Scholar
Hong J, Zhang R, Tang H, Wu S, Chen Y, Tan X. Comparison of triglyceride glucose index and modified triglyceride glucose indices in predicting cardiovascular diseases incidence among populations with cardiovascular-kidney-metabolic syndrome stages 0–3: a nationwide prospective cohort study. Cardiovasc Diabetol. 2025;24:98. https://doi.org/10.1186/s12933-025-02662-3.
Article CAS PubMed PubMed Central Google Scholar
Wu Y, Liu C, Cao J. Association between triglyceride-glucose index and its composite obesity indexes and cardio-renal disease: analysis of the NHANES 2013–2018 cycle. Front Endocrinol (Lausanne). 2025;16:1505808. https://doi.org/10.3389/fendo.2025.1505808.
Huang Y, Zhou Y, Xu Y, Wang X, Zhou Z, Wu K, et al. Inflammatory markers link triglyceride-glucose index and obesity indicators with adverse cardiovascular events in patients with hypertension: insights from three cohorts. Cardiovasc Diabetol. 2025;24:11. https://doi.org/10.1186/s12933-024-02571-x.
Article CAS PubMed PubMed Central Google Scholar
Zhao Y, Hu Y, Smith JP, Strauss J, Yang G. Cohort profile: the China health and retirement longitudinal study (CHARLS). Int J Epidemiol. 2014;43:61–8. https://doi.org/10.1093/ije/dys203.
Unger T, Borghi C, Charchar F, Khan NA, Poulter NR, Prabhakaran D, et al. 2020 International Society of Hyperten
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