Implementing regulation—2017/2324—EN—glyphosate—EUR-Lex. [cited 2025 Aug 25]. Available from: https://eur-lex.europa.eu/eli/reg_impl/2017/2324/oj/eng

PubChem. Glyphosate. [cited 2025 Aug 25]. https://pubchem.ncbi.nlm.nih.gov/compound/3496

Lynch, D., Svoboda, J., Putta, S., Hofland, H. E. J., Chern, W. H., & Hansen, L. A. (2007). Mouse skin models for carcinogenic hazard identification: Utilities and challenges. Toxicologic Pathology, 35(7), 853–864.

Article  PubMed  CAS  Google Scholar 

Bodekær, M., Harrison, G. I., Philipsen, P., Petersen, B., Triguero-Mas, M., Schmalwieser, A. W., Rogowski-Tylman, M., Dadvand, P., Lesiak, A., Narbutt, J., Eriksen, P., Heydenreich, J., Nieuwenhuijsen, M., Thieden, E., Young, A. R., & Wulf, H. C. (2015). Personal UVR exposure of farming families in four European countries. Journal of Photochemistry and Photobiology, B: Biology, 153, 267–275.

Article  PubMed  Google Scholar 

Maibach, H. I. (1986). Irritation, sensitization, photoirritation and photosensitization assays with a glyphosate herbicide. Contact Dermatitis, 15(3), 152–156.

Article  PubMed  CAS  Google Scholar 

Heras-Mendaza, F., Casado-Fariñas, I., Paredes-Gascón, M., & Conde-Salazar, L. (2008). Erythema multiforme-like eruption due to an irritant contact dermatitis from a glyphosate pesticide. Contact Dermatitis, 59(1), 54–56.

Article  PubMed  Google Scholar 

Bradberry, S. M., Proudfoot, A. T., & Vale, J. A. (2004). Glyphosate poisoning. Toxicological Reviews., 23(3), 159–167.

Article  PubMed  CAS  Google Scholar 

Amerio, P., Motta, A., Toto, P., Pour, S. M., Pajand, R., Feliciani, C., & Tulli, A. (2004). Skin toxicity from glyphosate-surfactant formulation. Journal of Toxicology, Clinical Toxicology, 42(3), 317–319.

Article  PubMed  Google Scholar 

Fortes, C., Mastroeni, S., Segatto, M. M., Hohmann, C., Miligi, L., Bakos, L., & Bonamigo, R. (2016). Occupational exposure to pesticides with occupational sun exposure increases the risk for cutaneous melanoma. Journal of Occupational and Environmental Medicine, 58(4), 370–375.

Article  PubMed  CAS  Google Scholar 

Bukowska, B., Woźniak, E., Sicińska, P., Mokra, K., & Michałowicz, J. (2022). Glyphosate disturbs various epigenetic processes in vitro and in vivo – A mini review. Science of the Total Environment, 851, Article 158259.

Article  PubMed  CAS  Google Scholar 

Elie-Caille, C., Heu, C., Guyon, C., & Nicod, L. (2010). Morphological damages of a glyphosate-treated human keratinocyte cell line revealed by a micro- to nanoscale microscopic investigation. Cell Biology and Toxicology, 26(4), 331–339.

Article  PubMed  CAS  Google Scholar 

Heu, C., Berquand, A., Elie-Caille, C., & Nicod, L. (2012). Glyphosate-induced stiffening of HaCaT keratinocytes, a Peak Force Tapping study on living cells. Journal of Structural Biology, 178(1), 1–7.

Article  PubMed  CAS  Google Scholar 

Heu, C., Elie-Caille, C., Mougey, V., Launay, S., & Nicod, L. (2012). A step further toward glyphosate-induced epidermal cell death: Involvement of mitochondrial and oxidative mechanisms. Environmental Toxicology and Pharmacology, 34(2), 144–153.

Article  PubMed  CAS  Google Scholar 

Portier, C. J. (2020). A comprehensive analysis of the animal carcinogenicity data for glyphosate from chronic exposure rodent carcinogenicity studies. Environmental Health, 19(1), 18.

Article  PubMed  PubMed Central  CAS  Google Scholar 

George, J., Prasad, S., Mahmood, Z., & Shukla, Y. (2010). Studies on glyphosate-induced carcinogenicity in mouse skin: A proteomic approach. Journal Of Proteomics, 73(5), 951–964.

Article  PubMed  CAS  Google Scholar 

Wulf, H. C., Al-Chaer, R. N., Glud, M., Philipsen, P. A., & Lerche, C. M. (2021). A skin cancer prophylaxis study in hairless mice using methylene blue, riboflavin, and methyl aminolevulinate as photosensitizing agents in photodynamic therapy. Pharmaceuticals (Basel), 14(5), 433.

Article  PubMed  CAS  Google Scholar 

Pihl, C., Bendtsen, K. M. S., Jensen, H. E., Andersen, F., Bjerring, P., Haedersdal, M., & Lerche, C. M. (2023). Oral phytochemicals as photoprotectants in UVR exposed hairless mice: A study of hesperidin methyl chalcone, phloroglucinol, and syringic acid. Journal of Photochemistry and Photobiology, B: Biology, 246, Article 112760.

Article  PubMed  CAS  Google Scholar 

Donslund, M. F. S., Granborg, J. R., Niklas, A. A., Janfelt, C., Sloth, J. J., Philipsen, P. A., Wulf, H. C., & Lerche, C. M. (2025). Evaluation of the photocarcinogenic potential of perfluorooctanoic acid in mice after topical and oral exposure. Journal Of Investigative Dermatology, 145(6), 1509–1512.

Article  PubMed  CAS  Google Scholar 

Lerche, C. M., Al-Chaer, R. N., Glud, M., Philipsen, P. A., & Wulf, H. C. (2021). Few X-ray and PUVA treatments accelerate photocarcinogenesis in hairless mice. Photochemical & Photobiological Sciences, 20(10), 1299–1307.

Article  CAS  Google Scholar 

Lerche, C. M., Philipsen, P. A., Sehested, M., & Wulf, H. C. (2008). Photocarcinogenesis of topical tazarotene and isotretinoin alone and in combination with valproic acid in hairless mice. Experimental Dermatology, 17(11), 972–974.

Article  PubMed  CAS  Google Scholar 

Wulf, HChr. (1996). Dosimetry of UV radiation. Skin Research And Technology, 2(3), 101–102.

Article  PubMed  CAS  Google Scholar 

Lerche, C. M., Sepehri, M., Serup, J., Poulsen, T., & Wulf, H. C. (2015). Black tattoos protect against UVR-induced skin cancer in mice. Photoderm Photoimm Photomed., 31(5), 261–268.

Article  CAS  Google Scholar 

Thorling L, Albers CN, Ditlefsen C, Hansen B, Johnsen AR, Mortensen MH, Troldborg L. Grundvand. Status og udvikling 1989–2020. Teknisk rapport. GEUS; 2021 [cited 2025 Aug 25]. Available from: https://pub.geus.dk/da/publications/grundvand-status-og-udvikling-19892020-teknisk-rapport

Lerche, C., Togsverd-Bo, K., Philipsen, P., & Wulf, H. (2017). Impact of UVR exposure pattern on squamous cell carcinoma-A dose-delivery and dose-response study in pigmented hairless mice. IJMS., 18(12), 2738.

Article  PubMed  PubMed Central  Google Scholar 

Dannhorn, A., Kazanc, E., Ling, S., Nikula, C., Karali, E., Serra, M. P., Vorng, J. L., Inglese, P., Maglennon, G., Hamm, G., Swales, J., Strittmatter, N., Barry, S. T., Sansom, O. J., Poulogiannis, G., Bunch, J., Goodwin, R. J., & Takats, Z. (2020). Universal sample preparation unlocking multimodal molecular tissue imaging. Analytical Chemistry, 92(16), 11080–11088.

Article  PubMed  CAS  Google Scholar 

Hansen, C. F. M., Dobrovolskis, L., & Janfelt, C. (2025). Design and implementation of a desorption electro-flow focusing sprayer on an Orbitrap mass spectrometer for DESI mass spectrometry imaging at high spatial resolution and at high speed. Journal of the American Society for Mass Spectrometry, 36(3), 473–482.

Article  PubMed  CAS  Google Scholar 

Bokhart, M. T., Nazari, M., Garrard, K. P., & Muddiman, D. C. (2018). MSiReader v1.0: Evolving open-source mass spectrometry imaging software for targeted and untargeted analyses. Journal of the American Society for Mass Spectrometry, 29(1), 8–16.

Article  PubMed  CAS  Google Scholar 

Zhai, H., Chan, H. P., Hui, X., & Maibach, H. I. (2008). Skin decontamination of glyphosate from human skin in vitro. Food and Chemical Toxicology, 46(6), 2258–2260.

Article  PubMed  CAS  Google Scholar 

Pierce, J. S., Roberts, B., Kougias, D. G., Comerford, C. E., Riordan, A. S., Keeton, K. A., Reamer, H. A., Jacobs, N. F. B., & Lotter, J. T. (2020). Pilot study evaluating inhalation and dermal glyphosate exposure resulting from simulated heavy residential consumer application of Roundup®. Inhalation Toxicology, 32(8), 354–367.

Article  PubMed  CAS  Google Scholar 

Lerche, C. M., Philipsen, P. A., Poulsen, T., & Wulf, H. C. (2010). Topical hydrocortisone, clobetasol propionate, and calcipotriol do not increase photocarcinogenesis induced by simulated solar irradiation in hairless mice. Experimental Dermatology, 19(11), 973–979.

Article  PubMed  CAS  Google Scholar 

Lerche, C. M., Philipsen, P. A., & Wulf, H. C. (2013). X-rays and photocarcinogenesis in hairless mice. Archives of Dermatological Research, 305(6), 529–533.

Article  PubMed  CAS  Google Scholar 

Mesnage, R., Ferguson, S., Brandsma, I., Moelijker, N., Zhang, G., Mazzacuva, F., Caldwell, A., Halket, J., & Antoniou, M. N. (2022). The surfactant co-formulant POEA in the glyphosate-based herbicide RangerPro but not glyphosate alone causes necrosis in Caco-2 and HepG2 human cell lines and ER stress in the ToxTracker assay. Food and Chemical Toxicology, 168, Article 113380.

Article