Naghavi M, Vollset SE, Ikuta KS, et al. Global burden of bacterial antimicrobial resistance 1990–2021: a systematic analysis with forecasts to 2050. Lancet. 2024;404:1199–226. https://pubmed.ncbi.nlm.nih.gov/39299261/. Accessed 2025 Jan 18.
World Bank Group. Drug-resistant infections: a threat to our economic future. 2017. https://documents1.worldbank.org/curated/en/323311493396993758/pdf/final-report.pdf.
Halawa EM, Fadel M, Al-Rabia MW, et al. Antibiotic action and resistance: updated review of mechanisms, spread, influencing factors, and alternative approaches for combating resistance. Front Pharmacol. 2023;14:1305294.
World Health Organization. 2023 Antibacterial agents in clinical and preclinical development: an overview and analysis. 2024. https://www.who.int/publications/i/item/9789240094000.
Cavenagh Health. The reckoning of antimicrobial resistance: a new biological frontier. 2024. https://www.pharmafocusasia.com/whitepapers/the-reckoning-of-antimicrobial-resistance-a-new-biological-frontier. Accessed 2025 May 7.
Falcone M, Tiseo G, Galfo V, et al. Bloodstream infections in patients with rectal colonization by Klebsiella pneumoniae producing different type of carbapenemases: a prospective, cohort study (CHIMERA study). Clin Microbiol Infect. 2022;28:298.e1-298.e7.
Pouch SM, Patel G, AST Infectious Diseases Community of Practice. Multidrug-resistant gram-negative bacterial infections in solid organ transplant recipients-guidelines from the American Society of Transplantation Infectious Diseases Community of Practice. Clin Transplant. 2019;33:e13594.
Nanayakkara AK, Boucher HW, Fowler VG, Jezek A, Outterson K, Greenberg DE. Antibiotic resistance in the patient with cancer: escalating challenges and paths forward. CA Cancer J Clin. 2021;71:488–504.
Zheng Y, Chen Y, Yu K, et al. Fatal infections among cancer patients: a population-based study in the United States. Infect Dis Ther. 2021;10:871–95.
PubMed PubMed Central Google Scholar
Longitude Prize. Effectiveness of cancer treatments threatened by rising antibiotic resistance. London; 2020. https://amr.longitudeprize.org/resources/effectiveness-of-cancer-treatments-threatened-by-rising-antibiotic-resistance/. Accessed 2025 May 7.
Okamoto K, Santos CAQ. Management and prophylaxis of bacterial and mycobacterial infections among lung transplant recipients. Ann Transl Med. 2020;8:413.
CAS PubMed PubMed Central Google Scholar
van Rhijn N, Arikan-Akdagli S, Beardsley J, et al. Beyond bacteria: the growing threat of antifungal resistance. Lancet. 2024;404:1017–8. http://www.thelancet.com/article/S0140673624016957/fulltext. Accessed 2025 Jan 26.
Papanicolaou GA, Ustun C, Young J-AH, et al. Bloodstream infection due to vancomycin-resistant Enterococcus is associated with increased mortality after hematopoietic cell transplantation for acute leukemia and myelodysplastic syndrome: a multicenter, retrospective cohort study. Clin Infect Dis. 2019;69:1771–9.
CAS PubMed PubMed Central Google Scholar
Lay C, Law N, Holm AM, Benden C, Aslam S. Outcomes in cystic fibrosis lung transplant recipients infected with organisms labeled as pan-resistant: an ISHLT registry-based analysis. J Heart Lung Transplant. 2019;38:545–52.
Gudiol C, Albasanz-Puig A, Laporte-Amargós J, et al. Clinical predictive model of multidrug resistance in neutropenic cancer patients with bloodstream infection due to Pseudomonas aeruginosa. Antimicrob Agents Chemother. 2020;64:e02494.
CAS PubMed PubMed Central Google Scholar
Averbuch D, Tridello G, Hoek J, et al. Intercontinental study on pre-engraftment and post-engraftment Gram-negative rods bacteremia in hematopoietic stem cell transplantation patients: risk factors and association with mortality. J Infect. 2020;81:882–94.
Giannella M, Freire M, Rinaldi M, et al. Development of a risk prediction model for carbapenem-resistant enterobacteriaceae infection after liver transplantation: a multinational cohort study. Clin Infect Dis. 2021;73:e955–66.
Albasanz-Puig A, Durà-Miralles X, Laporte-Amargós J, et al. Effect of combination antibiotic empirical therapy on mortality in neutropenic cancer patients with Pseudomonas aeruginosa pneumonia. Microorganisms. 2022;10:733.
CAS PubMed PubMed Central Google Scholar
Bergas A, Albasanz-Puig A, Fernández-Cruz A, et al. Real-life use of ceftolozane/tazobactam for the treatment of bloodstream infection due to Pseudomonas aeruginosa in neutropenic hematologic patients: a matched control study (ZENITH Study). Microbiol Spectr. 2022;10:e0229221.
Royo-Cebrecos C, Laporte-Amargós J, Peña M, et al. Pseudomonas aeruginosa bloodstream infections in patients with cancer: differences between patients with hematological malignancies and solid tumors. Pathogens. 2022;11:1132.
CAS PubMed PubMed Central Google Scholar
Rinaldi M, Bonazzetti C, Gallo M, et al. Validation of the INCREMENT-SOT-CPE score in a large cohort of liver transplant recipients with carbapenem-resistant Enterobacterales infection. Transpl Infect Dis. 2023;25:e14036.
Belga S, Chiang D, Kabbani D, Abraldes JG, Cervera C. The direct and indirect effects of vancomycin-resistant enterococci colonization in liver transplant candidates and recipients. Expert Rev Anti Infect Ther. 2019;17(5):363–73.
Hansen B-A, Wendelbo Ø, Bruserud Ø, Hemsing AL, Mosevoll KA, Reikvam H. Febrile neutropenia in acute leukemia epidemiology, etiology, pathophysiology and treatment. Mediterr J Hematol Infect Dis. 2020;12:e2020009.
Gudiol C, Sabé N, Carratalà J. Is hospital-acquired pneumonia different in transplant recipients? Clin Microbiol Infect. 2019;25:1186–94.
Garcia-Vidal C, Stern A, Gudiol C. Multidrug-resistant, gram-negative infections in high-risk haematologic patients: an update on epidemiology, diagnosis and treatment. Curr Opin Infect Dis. 2021;34:314–22.
Congedi S, Navalesi P, Boscolo A. Multidrug-resistant organisms in lung transplant: a narrative review. Curr Opin Organ Transplant. 2023;28:174–9.
PubMed PubMed Central Google Scholar
Giannella M, Rinaldi M, Viale P. Antimicrobial resistance in organ transplant recipients. Infect Dis Clin N Am. 2023;37:515–37.
Freire MP, Pouch S, Manesh A, Giannella M. Burden and management of multi-drug resistant organism infections in solid organ transplant recipients across the world: a narrative review. Transpl Int. 2024;37:12469.
CAS PubMed PubMed Central Google Scholar
Pilmis B, Weiss E, Scemla A, et al. Multidrug-resistant Enterobacterales infections in abdominal solid organ transplantation. Clin Microbiol Infect. 2023;29:38–43.
Huggins J, Barnett I, David MZ. Effects of antimicrobial therapy duration and class on risk of antimicrobial-resistant Gram-negative bacillus bloodstream infection in patients with AML. Transpl Infect Dis. 2023;25:e14115.
Trecarichi EM, Giuliano G, Cattaneo C, et al. Bloodstream infections due to Gram-negative bacteria in patients with hematologic malignancies: updated epidemiology and risk factors for multidrug-resistant strains in an Italian perspective survey. Int J Antimicrob Agents. 2023;61:106806.
Haidar G, Green M, American Society of Transplantation Infectious Diseases Community of Practice. Intra-abdominal infections in solid organ transplant recipients: guidelines from the American Society of Transplantation Infectious Diseases Community of Practice. Clin Transplant. 2019;33:e13595.
Danielsen AS, Franconeri L, Page S, et al. Clinical outcomes of antimicrobial resistance in cancer patients: a systematic review of multivariable models. BMC Infect Dis. 2023;23:247.
PubMed PubMed Central Google Scholar
Mercuro NJ, Gill CM, Kenney RM, Alangaden GJ, Davis SL. Treatment and outcomes of Enterococcus faecium bloodstream infections in solid organ transplant recipients. Transpl Infect Dis. 2020;22:e13251.
Oltolini C, Greco R, Galli L, et al. Infections after allogenic transplant with post-transplant cyclophosphamide: impact of donor HLA matching. Biol Blood Marrow Transplant. 2020;26:1179–88.
Busani S, Serafini G, Mantovani E, et al. Mortality in patients with septic shock by multidrug resistant bacteria: risk factors and impact of sepsis treatments. J Intensive Care Med. 2019;34:48–54.
Boyd AM, Perissinotti AJ, Nagel JL, Frame DG, Marini BL. Risk factors for cefepime nonsusceptible Gram-negative infections in allogeneic hematopoietic cell transplant recipients. J Oncol Pharm Pract. 2019;25:279–88.
Satlin MJ, Chavda KD, Baker TM, et al. Colonization with levofloxacin-resistant extended-spectrum β-lactamase-producing Enterobacteriaceae and risk of bacteremia in hematopoietic stem cell transplant recipients. Clin Infect Dis. 2018;67:1720–8.
CAS PubMed PubMed Central Google Scholar
Errico G, Gagliotti C, Monaco M, et al. Colonization and infection due to carbapenemase-producing Enterobacteriaceae in liver and lung transplant recipients and donor-derived transmission: a prospective cohort study conducted in Italy. Clin Microbiol Infect. 2019;25:203–9.
Antonio M, Gudiol C, Royo-Cebrecos C, Grillo S, Ardanuy C, Carratalà J. Current etiology, clinical features and outcomes of bacteremia in older patients with solid tumors. J Geriatr Oncol. 2019;10:246–51.
Heidenreich D, Kreil S, Jawhar M, et al. Course of colonization by multidrug-resistant organisms after allogeneic hematopoietic cell transplantation. Ann Hematol. 2018;97:2501–8.
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