Systematic Review and Meta-analysis of the Efficacy and Effectiveness of the Unified Protocol for Emotional Disorders in Group Format for Adults

Aguinis, H., Gottfredson, R. K., & Wright, T. A. (2011). Best-practise recommendations for estimating interaction effects using meta-analysis. Journal of Organizational Behavior, 32, 1033–1043.

Article  Google Scholar 

*Amirpour, L., Gharaee, B., & Birashk, B. (2018). Efficacy of group transdiagnostic cognitive-behavioral therapy on subclinical paranoia. Iran Journal Psychiatry and Behavioral Sciences, 12(4). https://doi.org/10.5812/ijpbs.65161.

*Bameshgi, M., Kimiaei, A., & Mashhadi, A. (2021). Effectiveness of a unified protocol on emotion regulation and experiential avoidance in women with comorbid major depressive and generalized anxiety symptoms. Journal of Fundamentals of Mental Health, 22(6), 341–348. https://doi.org/10.22038/JFMH.2020.17559.

Barlow, D. H., Farchione, T. J., Fairholme, C. P., Ellard, K. K., Boisseau, C. L., Allen, L. B., & Ehrenreich-May, J. (2010). Unified Protocol for transdiagnostic treatment of emotional disorders: Therapist guide. Oxford University Press.

Bentley, K. H., Sauer-Zavala, S., Cassiello-Robbins, F., Conklin, L. R., Vento, S. V., & Homer, D. (2017). Treating suicidal thoughts and behaviors within an emotional disorders framework: Acceptability and feasibility of the Unified Protocol in an inpatient setting. Behavior Modification, 41(4), 529–557. https://doi.org/10.1177/0145445516689661. journals.sagepub.com/home/bmo.

Article  PubMed  Google Scholar 

*Bentley, K. H., Sauer-Zavala, S., Stevens, K. T., & Washburn, J. J. (2018). Implementing an evidence-based psychological intervention for suicidal thoughts and behaviors on an inpatient unit: Process, challenges, and initial findings. General Hospital Psychiatry, 63, 76-82. https://doi.org/10.1016/j.genhosppsych.2018.0 9.012.

Bullis, J. R., Fortune, M. R., Farchione, T. J., & Barlow, D. H. (2014). A preliminary investigation of the long-term outcome of the Unified Protocol for transdiagnostic treatment of emotional disorders. Comprehensive Psychiatry, 55(8), 1920–1927. https://doi.org/10.1016/j.comppsych.2014.07.016

Article  PubMed  PubMed Central  Google Scholar 

*Bullis, J. R., Sauer-Zavala, S., Bentley, K. H., Thompson-Hollands, J., Carl, J. R., & Barlow, D. H. (2015). The Unified Protocol for transdiagnostic treatment of emotional disorders: Preliminary exploration of effectiveness for group delivery. Behavior Modification, 39(2), 295-321. https://doi.org/10.1177/0145445514553094.

Butler, E., Matcham, F., & Chalder, T. (2016). A systematic review of anxiety amongst people with multiple sclerosis. Multiple Sclerosis and Related Disorders, 10, 145–168. https://doi.org/10.1016/j.msard.2016.10.003

Article  PubMed  Google Scholar 

Carlucci, L., Saggino, A., & Balsamo, M. (2021). On the efficacy of the unified protocol for transdiagnostic treatment of emotional disorders: A systematic review and meta-analysis, Clinical Psychology Review, 87. https://doi.org/10.1016/j.cpr.2021.101999.

Christensen, M. K., Lim, C. C. W., Saha, S., Plana-Ripoll, O., Cannon, D., Presley, F., Weye, N., Momen, N. C., Whiteford, H. A., Iburg, K. M., & McGrath, J. J. (2020). The cost of mental disorders: A systematic review. Epidemiology and Psychiatric Sciences, 1(29), 1–8. https://doi.org/10.1017/S204579602000075X

Article  Google Scholar 

*Corpas, J., Moriana, J. A., Venceslá, J. F., & Gálvez-Lara, M. (2022). Effectiveness of brief group transdiagnostic therapy for emotional disorders in primary care: A randomized controlled trial identifying predictors of outcome. Psychotherapy Research, 32(4), 456-469. https://doi.org/10.1080/10503307.2021.1952331.

Dalgleish, T., Black, M., Johnston, D., & Bevan, A. (2020). Transdiagnostic approaches to mental health problems: Current status and future directions. Journal of Consulting and Clinical Psychology, 88(3), 179–195. https://doi.org/10.1037/ccp0000482

Article  PubMed  PubMed Central  Google Scholar 

*De Ornelas Maia, A. C. C., Braga, A. A., Nunes, C. A., Nardi, A. E., & Silva, A. C. (2013). Transdiagnostic treatment using a unified protocol: Application for patients with a range of comorbid mood and anxiety disorders. Trends Psychiatry Psychother, 35(2), 134-140.

*De Ornelas Maia, A. C. C., Nardi, A. E., & Cardoso, A. (2015). The utilization of Unified Protocols in behavioral cognitive therapy in transdiagnostic group subjects: A clinical trial. Journal of Affective Disorders, 172, 79–183. https://doi.org/10.1016/j.jad.2014.09.023.

*De Ornelas Maia, A. C. C., Sanford, J., Boettcher, H., Nardi, A. E., & Barlow, D. H. (2017). Improvement in quality of life and sexual functioning in a comorbid sample after the unified protocol transdiagnostic group treatment. Journal of Psychiatric Research, 93, 30-36. https://doi.org/10.1016/j.jpsychires.2017.05.013.

Ehrenreich-May, J., Bilek, E. L., Queen, A. H., & Rodriguez, J. H. (2012). A Unified Protocol for the group treatment of childhood anxiety and depression. Spanish Journal of Clinical Psychology, 17(3), 219–236.

Google Scholar 

Ellard, K. K., Fairholme, C. P., Boisseau, C. L., Farchione, T. J., & Barlow, D. H. (2010). Unified Protocol for the transdiagnostic treatment of emotional disorders: Protocol development and initial outcome data. Cognitive and Behavioral Practice, 17(1), 88–101. https://doi.org/10.1016/j.cbpra.2009.06.002

Article  PubMed  PubMed Central  Google Scholar 

Farchione, T. J., Fairholme, T. J., Ellard, K. K., Boisseau, C. L., Thompson-Hollands, J., Carl, J. R., Gallagher, M. W., & Barlow, D. H. (2012). Unified Protocol for transdiagnostic treatment of emotional disorders: A randomized controlled trial. Behavior Therapy, 43(3), 666–678. https://doi.org/10.1016/j.beth.2012.01.001

Article  PubMed  PubMed Central  Google Scholar 

*Ghapanchi, A., Masjedi-Arani, A., Sadeghi, Amir., Lighvan, M. A. Z., Isfeedvajani, M. S., & Eslamipour, S. (2022). The effectiveness of the Unified Protocol on symptoms, quality of life, negative affect, and negative reactivity in irritable bowel syndrome patients in comorbidity with anxiety and depression. Medical Science, 26(119),196–211. https://doi.org/10.54905/disssi/v26i119/ms34e1964.

Goretti, B., Portaccio, E., Zipoli, V., Hakiki, B., Siracusa, G., Sorbi, S., & Amato, M. P. (2009). Coping strategies, psychological variables and their relationship with quality of life in multiple sclerosis. Neurological Sciences, 30(1), 15–20. https://doi.org/10.1007/s10072-008-0009-3

Article  PubMed  Google Scholar 

*Grill, S. S., Castañeiras, C., & Fasciglione, M. P. (2017). Aplicación grupal del Protocolo Unificado para el tratamiento transdiagnóstico de los trastornos emocionales en población argentina. Revista de Psicopatología y Psicología Clínica, 22(3), 171-181. https://doi.org/10.5944/rppc.vol.22.num.3.2017.18122

Higgins, J. P. T., & Thompson, S. G. (2002). Quantifying heterogeneity in a meta-analysis. Statistics in Medicine, 21, 1539–1558. https://doi.org/10.1002/sim.1186

Article  PubMed  Google Scholar 

Hollon, S. D., & Ponniah, K. (2010). A review of empirically supported psychological therapies for mood disorders in adults. Depression and Anxiety, 27(10), 891–932. https://doi.org/10.1002/da.20741

Article  PubMed  PubMed Central  Google Scholar 

Huedo-Medina, T., Sánchez-Meca, J., Marín-Martínez, F., & Botella, J. (2006). Assessing heterogeneity in meta-analysis: Q statistics or 12 index? Psychological Methods, 11(2), 193–206. https://doi.org/10.1037/1082-989X.11.2.193

Article  PubMed  Google Scholar 

IsHak, W. W., Greenberg, J. M., Balayan, K., Kapitanski, N., Jeffrey, J., Fathy, H., Fakhry, H., & Rapaport, M. H. (2011). Quality of life: The ultimate outcome measure of interventions in major depressive disorder. Harvard Review of Psychiatry, 19(5), 229–239. https://doi.org/10.3109/10673229.2011.614099

Article  PubMed  Google Scholar 

*Johari-Fard, R., & Ghafoupour, R. (2015). The effectiveness of Unified Treatment approach on quality of life and symptoms of patients with irritable bowel syndrome referred to gastrointestinal clinics. International Journal Body Mind & Culture, 2(2), 85-94. https://doi.org/10.1590/S0004-2803.201700000-08.

*Kivity, Y., Sela, M. S., Yariv, A., Koubi, M., Saad, A., Fennig, S., & Bloch, Y. (2020). Transdiagnostic treatment of anxiety disorders in a group format based on the principles of the Unified Protocol: A preliminary intensive measurement examination of process and outcome. International Journal Cognitive Therapy, 13, 127–145. https://doi.org/10.1007/s41811-019-00059-1.

*Laposa, J. M., Mancuso, E., Abraham, G., & Loli-Dano, L. (2017). Unified Protocol transdiagnostic treatment in group format: A preliminary investigation with anxious individuals. Behavior Modification, 41(2), 253–268. https://doi.org/10.1177/0145445516667664.

Lipsey, M. W., & Wilson, D. B. (2001). Practical meta-analysis. Sage Publications.

*Mohammadpour, M., Sadeghi, K., Foroughi, A., Amiri, S., Pouyanfard, S., Parvizifard, A., & Khoramniya, S. (2018). The Unified Protocol for transdiagnostic treatment of emotional disorders: treatment of comorbid psychopathology accompanying a generalized anxiety disorder. Internacional Journal Behavioral Sciences, 12(3), 125-131.

Moher, D., Shamseer, L., Clarke, M., Ghersi, D., Liberati, A., Petticrew, M., Shekelle, P., Stewart, L. A., PRISMA-P Group. (2015). Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement. Systematic Reviews, 4(1), 1.

Article  PubMed  PubMed Central  Google Scholar 

*Mohsenabadi, H., Zanjani, Z., Shabani, M. J., & Arj, A. (2018). A randomized clinical trial of the Unified Protocol for transdiagnostic treatment of emotional and gastrointestinal symptoms in patients with irritable bowel syndrome: Evaluating efficacy and mechanism of change. Journal of Psychosomatic Research, 113, 8–15.https://doi.org/10.1016/j.jpsychores.2018.07.00 3.

Morris, S. B. (2008). Estimating effect sizes from pretest-posttest-control group designs. Original Research Methods, 11(2), 364–386. https://doi.org/10.1177/1094428106291059

Article  Google Scholar 

*Mousavi, E., Hosseini, S., Bakhtiyari, M., Mohammadi, A., Isfeedvajani, M. S., Arani, A. M., & Sadaat, S. H. (2019). Comparing the effectiveness of the Unified Protocol transdiagnostic and mindfulness-based stress reduction program on anxiety and depression in infertile Women receiving In Vitro fertilisation. Journal of Research in Medical and Dental Science, 7(2), 44-51.

*Nazari, N., Sadeghi, M., Ghadampour, E., & Mirzaeefar, D. (2020). Transdiagnostic treatment of emotional disorders in people with multiple sclerosis: Randomized controlled trial. BMC Psycholy, 8, 114. https://doi.org/10.1186/s40359-020-00480-8.

Olatunji, B. O., Cisler, J. M., & Tolin, D. F. (2007). Quality of life in the anxiety disorders: A meta-analytic review. Clinical Psychology Review, 27(5), 572–581. https://doi.org/10.1016/j.cpr.2007.01.015

Article  PubMed  Google Scholar 

*Osma, J., Castellano, C., Crespo, E., & García-Palacios, A. (2015). The Unified Protocol for transdiagnostic treatment of emotional disorders in group format in a Spanish public mental health setting. Behavioral Psychology, 23(3), 447-466.

* Osma, J., Peris-Baquero, O., Suso-Ribera, C., Farchione, T. J., & Barlow, D. H. (2021). Effectiveness of the Unified Protocol for transdiagnostic treatment of emotional disorders in group format in Spain: Results from a randomized controlled trial with 6-months follow-up. Psychotherapy Research, 32(3), 329-342. https://doi.org/10.1080/10503307.2021.1939190.

*Osma, J., Quilez-Orden, A. B., Ferreres-Galán, V., Meseguer, M. C., & Ariza, S. (2022). Feasibility and clinical usefulness of the Unified Protocol in women survivors of violence. Journal of Child and Family Studies,32(9) ,2598–2613. https://doi.org/10.1007/s10826-022-02226-z.

*Paul, N. F., & Caver, K. A. (2021). A pilot study of a brief group adaptation of the Unified Protocol in integrated primary care. Psychological Services, 18(3), 416–425. https://doi.org/10.1037/ser0000406.

*Powell, C., Farchione, T. J., Barlow, D. H., & Leung, P. (2021). A pilot trial of a transdiagnostic treatment for emotional disorders-A locally adapted variant of group Unified Protocol (UP) for chinese adults. Translational behavioral medicine, 11(5), 1142–1150. https://doi.org/10.1093/tbm/ibaa104.

*Reinholt, N., Aharoni, R., Winding, C., Rosenberg, N., Rosenbaum, B, & Arnfred, S. (2017). Transdiagnostic group CBT for anxiety disorders: The Unified Protocol in mental health services. Cognitive Behaviour Therapy, 46(1), 29-43. https://doi.org/10.1080/16506073.2016.1227360.

Review Manager (RevMan) (2020) [Computer program]. Version 5.4. The Cochrane Collaboration.

*Rodriguez-Moreno, S., Farchione, T. J., Roca, P., Marín, C., Guillén, A. I., & Panadero, S. (2020). Initial effectiveness evaluation of the Unified Protocol for transdiagnostic treatment of emotional disorders for homeless women. Behavior modification, 1–23. https://doi.org/10.1177/0145445520982562.

*Roushani, K., Nejad, S. B., Arshadi, N., Honarmand, M. M., & Fakhri, A. (2016). Examining the efficacy of the unified transdiagnostic treatment on social anxiety and positive and negative affect in students. Razavi International Journal of Medecine, 4(4). https://doi.org/10.17795/rijm41233.

Sakiris, N., & Berle, D. (2019). A systematic review and meta-analysis of the Unified Protocol as a transdiagnostic emotion regulation based intervention. Clinical Psychology Review, 72, 101751. https://doi.org/10.1016/j.cpr.2019.101751

Article  PubMed  Google Scholar 

Sawilowsky, S. (2009). New effect size rules of thumb. Journal of modern applied statistical methods, 8(2). https://doi.org/10.22237/jmasm/1257035100.

Saxena, S., Thornicroft, G., Knapp, M., & Whiteford, H. (2007). Resources for mental health: Scarcity, inequity, and inefficiency. The Lancet, 370(9590), 878–889. https://doi.org/10.1016/S0140-6736(07)61239-2

Article  Google Scholar 

Sloan, D. M., Feinstein, B. A., Gallagher, M. W., Beck, J. G., & Keane, T. M. (2013). Efficacy of group treatment for posttraumatic stress disorder symptoms: A meta-analysis. Psychological Trauma: Theory, Research, Practice, and Policy, 5, 176–183. https://doi.org/10.1037/a002629

Article  Google Scholar 

Steenkamp, M. M., Litz, B. T., Hoge, C. W., & Marmar, C. R. (2015). Psychotherapy for military-related PTSD: A review of randomized clinical trials. The Journal of the American Medical Association, 314, 489–500. https://doi.org/10.1001/jama.2015.8370

Article  CAS  PubMed  Google Scholar 

Sudhir, P. M., Sharma, M. P., Mariamma, P., & Subbakrishna, D. K. (2012). Quality of life in anxiety disorders: Its relation to work and social functioning and dysfunctional cognitions: An exploratory study from India. Asian Journal of Psychiatry, 5(4), 309–314. https://doi.org/10.1016/j.ajp.2012.05.006

Article  PubMed  Google Scholar 

Comments (0)

No login
gif