Therapeutic importance and diagnostic function of circRNAs in urological cancers: from metastasis to drug resistance

Chen, L., Wang, C., Sun, H., Wang, J., Liang, Y., Wang, Y., & Wong, G. (2021). The bioinformatics toolbox for circRNA discovery and analysis. Briefings in Bioinformatics, 22(2), 1706–28.

Article  PubMed  CAS  Google Scholar 

Jeck, W. R., & Sharpless, N. E. (2014). Detecting and characterizing circular RNAs. Nature Biotechnology, 32(5), 453–461.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Chen, C. Y., & Sarnow, P. (1995). Initiation of protein synthesis by the eukaryotic translational apparatus on circular RNAs. Science, 268(5209), 415–417.

Article  PubMed  CAS  Google Scholar 

Sanger, H. L., et al. (1976). Viroids are single-stranded covalently closed circular RNA molecules existing as highly base-paired rod-like structures. Proceedings of the National Academy of Sciences of the United States of America, 73(11), 3852–3856.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Hsu, M. T., & Coca-Prados, M. (1979). Electron microscopic evidence for the circular form of RNA in the cytoplasm of eukaryotic cells. Nature, 280(5720), 339–340.

Article  PubMed  CAS  Google Scholar 

Patop, I. L., Wüst, S., & Kadener, S. (2019). Past, present, and future of circRNAs. The EMBO Journal, 38(16), e100836.

Article  PubMed  PubMed Central  Google Scholar 

Cocquerelle, C., et al. (1993). Mis-splicing yields circular RNA molecules. The FASEB Journal, 7(1), 155–160.

Article  PubMed  CAS  Google Scholar 

Salzman, J., Gawad, C., Wang, P. L., Lacayo, N., & Brown, P. O. (2012, Feb 1). Circular RNAs are the predominant transcript isoform from hundreds of human genes in diverse cell types. PloS One, 7(2), e30733.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Memczak, S., Jens, M., Elefsinioti, A., Torti, F., Krueger, J., Rybak, A., Maier, L., Mackowiak, S. D., Gregersen, L. H., Munschauer, M., & Loewer, A. (2013, Mar 21). Circular RNAs are a large class of animal RNAs with regulatory potency. Nature, 495(7441), 333–338.

Article  PubMed  CAS  Google Scholar 

Ivanov, A., Memczak, S., Wyler, E., Torti, F., Porath, H. T., Orejuela, M. R., Piechotta, M., Levanon, E. Y., Landthaler, M., Dieterich, C., & Rajewsky, N. (2015, Jan 13). Analysis of intron sequences reveals hallmarks of circular RNA biogenesis in animals. Cell Reports, 10(2), 170–177.

Article  PubMed  CAS  Google Scholar 

Ye, C. Y., Chen, L., Liu, C., Zhu, Q. H., & Fan, L. (2015, Oct). Widespread noncoding circular RNA s in plants. New Phytologist, 208(1), 88–95.

Article  PubMed  CAS  Google Scholar 

Danan, M., Schwartz, S., Edelheit, S., & Sorek, R. (2012, Apr 1). Transcriptome-wide discovery of circular RNAs in Archaea. Nucleic Acids Research, 40(7), 3131–3142.

Article  PubMed  CAS  Google Scholar 

Ashwal-Fluss, R., Meyer, M., Pamudurti, N. R., Ivanov, A., Bartok, O., Hanan, M., Evantal, N., Memczak, S., Rajewsky, N., & Kadener, S. (2014, Oct 2). circRNA biogenesis competes with pre-mRNA splicing. Molecular Cell, 56(1), 55–66.

Article  PubMed  CAS  Google Scholar 

Li, X., Yang, L., & Chen, L. L. (2018). The biogenesis, functions, and challenges of circular RNAs. Molecular Cell, 71(3), 428–442.

Article  PubMed  CAS  Google Scholar 

Zhang, X. O., et al. (2014). Complementary sequence-mediated exon circularization. Cell, 159(1), 134–147.

Article  PubMed  CAS  Google Scholar 

Sha, J., et al. (2016). Curcumin induces G0/G1 arrest and apoptosis in hormone independent prostate cancer DU-145 cells by down regulating Notch signaling. Biomedicine & Pharmacotherapy, 84, 177–184.

Article  CAS  Google Scholar 

Zhang, Y., et al. (2013). Circular intronic long noncoding RNAs. Molecular Cell, 51(6), 792–806.

Article  PubMed  CAS  Google Scholar 

Li, Z., Huang, C., Bao, C., Chen, L., Lin, M., Wang, X., Zhong, G., Yu, B., Hu, W., Dai, L., & Zhu, P. (2015). Exon-intron circular RNAs regulate transcription in the nucleus. Nature Structural & Molecular Biology, 22(3), 256–264.

Article  Google Scholar 

Zhang, M., Bai, X., Zeng, X., Liu, J., Liu, F., & Zhang, Z. (2021, Dec). circRNA-miRNA-mRNA in breast cancer. Clinica Chimica Acta, 1(523), 120–130.

Article  Google Scholar 

Mirzaei, S., Gholami, M. H., Hushmandi, K., Hashemi, F., Zabolian, A., Canadas, I., Zarrabi, A., Nabavi, N., Aref, A. R., Crea, F., & Wang, Y. (2022, Mar 2). The long and short non-coding RNAs modulating EZH2 signaling in cancer. Journal of Hematology & Oncology, 15(1), 18.

Article  CAS  Google Scholar 

Mirzaei, S., Zarrabi, A., Hashemi, F., Zabolian, A., Saleki, H., Ranjbar, A., Saleh, S. H., Bagherian, M., & Sharifzadeh, S. O., Hushmandi K, Liskova A. (2021, Jul). Regulation of nuclear factor-KappaB (NF-κB) signaling pathway by non-coding RNAs in cancer: Inhibiting or promoting carcinogenesis? Cancer Letters, 1(509), 63–80.

Article  Google Scholar 

Yuan, G., et al. (2021). Upregulated circRNA_102231 promotes gastric cancer progression and its clinical significance. Bioengineered, 12(1), 4936–4945.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Wong, C. H., et al. (2022). CircRTN4 promotes pancreatic cancer progression through a novel CircRNA-miRNA-lncRNA pathway and stabilizing epithelial-mesenchymal transition protein. Molecular Cancer, 21(1), 10.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Ju, Y., et al. (2021). CircRNA ANXA2 promotes lung cancer proliferation and metastasis by upregulating PDPK1 expression. Journal of Oncology, 2021, 4526609.

Article  PubMed  PubMed Central  Google Scholar 

Huang, X. Y., et al. (2020). Exosomal circRNA-100338 promotes hepatocellular carcinoma metastasis via enhancing invasiveness and angiogenesis. Journal of Experimental & Clinical Cancer Research, 39(1), 20.

Article  CAS  Google Scholar 

Tan, L., Huang, Z., Chen, Z., Chen, S., Ye, Y., Chen, T., & Chen, Z. (2023, Jan 2). CircRNA_001895 promotes sunitinib resistance of renal cell carcinoma through regulation of apoptosis and DNA damage repair. Journal of Chemotherapy, 35(1), 11–18.

Article  PubMed  CAS  Google Scholar 

Xu, J., et al. (2020). CircRNA-SORE mediates sorafenib resistance in hepatocellular carcinoma by stabilizing YBX1. Signal Transduction and Targeted Therapy, 5(1), 298.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Wang, H., et al. (2019). CircRNA circ_0067934 overexpression correlates with poor prognosis and promotes thyroid carcinoma progression. Medical Science Monitor, 25, 1342–1349.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Zhang, S., et al. (2019). CircRNA_0000502 promotes hepatocellular carcinoma metastasis and inhibits apoptosis through targeting microRNA-124. Journal of BUON, 24(6), 2402–2410.

PubMed  Google Scholar 

Peng, Q. S., et al. (2020). circRNA_0000140 suppresses oral squamous cell carcinoma growth and metastasis by targeting miR-31 to inhibit Hippo signaling pathway. Cell Death & Disease, 11(2), 112.

Article  CAS  Google Scholar 

Zhang, X., et al. (2018). circRNA_104075 stimulates YAP-dependent tumorigenesis through the regulation of HNF4a and may serve as a diagnostic marker in hepatocellular carcinoma. Cell Death & Disease, 9(11), 1091.

Article  Google Scholar 

Su, Y., et al. (2019). CircRNA Cdr1as functions as a competitive endogenous RNA to promote hepatocellular carcinoma progression. Aging (Albany NY), 11(19), 8183–8203.

Article  PubMed  Google Scholar 

Liu, Z., et al. (2019). CircRNA-5692 inhibits the progression of hepatocellular carcinoma by sponging miR-328-5p to enhance DAB2IP expression. Cell Death & Disease, 10(12), 900.

Article  CAS  Google Scholar 

Li, C., et al. (2021). CircRNA NRIP1 promotes papillary thyroid carcinoma progression by sponging mir-195-5p and modulating the P38 MAPK and JAK/STAT pathways. Diagnostic Pathology, 16(1), 93.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Yang, L., Zou, X., Zou, J., & Zhang, G. (2021, May 1). Functions of circular RNAs in bladder, prostate and renal cell cancer. Molecular Medicine Reports, 23(5), 1–2.

Article  CAS  Google Scholar 

Osca-Verdegal, R., et al. (2022). Use of circular RNAs in diagnosis, prognosis and therapeutics of renal cell carcinoma. Frontiers in Cell and Development Biology, 10, 879814.

Article  Google Scholar 

Cai, Z., & Li, H. (2020). Circular RNAs and bladder cancer. Oncotargets and Therapy, 13, 9573–9586.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Liu, X., et al. (2021). Circular RNAs in prostate cancer: Biogenesis,biological functions, and clinical significance. Molecular Therapy--Nucleic Acids, 26, 1130–1147.

Article  PubMed  PubMed Central 

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