Colorectal cancer: a comprehensive review of carcinogenesis, diagnosis, and novel strategies for classified treatments

Singh, M. P., Rai, S., Pandey, A., Singh, N. K., & Srivastava, S. (2021). Molecular subtypes of colorectal cancer: An emerging therapeutic opportunity for personalized medicine. Genes & diseases, 8(2), 133–145.

Article  CAS  Google Scholar 

Tang, X., Qiao, X., Chen, C., Liu, Y., Zhu, J., & Liu, J. (2019). Regulation mechanism of long noncoding RNAs in colon cancer development and progression. Yonsei Medical Journal, 60(4), 319–325.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Xie, Y., Shi, L., He, X., & Luo, Y. (2021). Gastrointestinal cancers in China, the USA, and Europe. Gastroenterology report, 9(2), 91–104.

Article  PubMed  PubMed Central  Google Scholar 

Fang, L., Yang, Z., Zhang, M., Meng, M., Feng, J., & Chen, C. (2021). Clinical characteristics and survival analysis of colorectal cancer in China: A retrospective cohort study with 13,328 patients from southern China. Gastroenterology report, 9(6), 571–582.

Article  PubMed  PubMed Central  Google Scholar 

Ciardiello, D., Vitiello, P. P., Cardone, C., Martini, G., Troiani, T., Martinelli, E., et al. (2019). Immunotherapy of colorectal cancer: Challenges for therapeutic efficacy. Cancer treatment reviews, 76, 22–32.

Article  PubMed  CAS  Google Scholar 

Xiong, Y., Wang, Y., & Tiruthani, K. (2019). Tumor immune microenvironment and nano-immunotherapeutics in colorectal cancer. Nanomedicine: Nanotechnology, Biology and Medicine, 21, 102034.

Article  PubMed  CAS  Google Scholar 

Sillo, T., Beggs, A., Morton, D., & Middleton, G. (2019). Mechanisms of immunogenicity in colorectal cancer. Journal of British Surgery, 106(10), 1283–1297.

Article  CAS  Google Scholar 

Forster, S., & Radpour, R. (2020). Molecular immunotherapy: Promising approach to treat metastatic colorectal cancer by targeting resistant cancer cells or cancer stem cells. Frontiers in oncology, 10, 569017.

Article  PubMed  PubMed Central  Google Scholar 

Hanna, J., Michael, G., Hoover, J., Herbert, C., Pinedo, H., & Finer, M. (2006). Active specific immunotherapy with autologous tumor cell vaccines for stage II colon cancer: Logistics, efficacy, safety and immunological pharmacodynamics. Human vaccines, 2(4), 185–191.

Article  PubMed  CAS  Google Scholar 

Ganesh, K., Stadler, Z. K., Cercek, A., Mendelsohn, R. B., Shia, J., Segal, N. H., et al. (2019). Immunotherapy in colorectal cancer: Rationale, challenges and potential. Nature reviews Gastroenterology & hepatology, 16(6), 361–375.

Article  Google Scholar 

Abakushina, E., Gelm, Y. V., Pasova, I., & Bazhin, A. (2019). Immunotherapeutic approaches for the treatment of colorectal cancer. Biochemistry (Moscow), 84, 720–728.

Article  PubMed  CAS  Google Scholar 

Bittoni, A., Sotte, V., Meletani, T., Cantini, L., Giampieri, R., & Berardi, R. (2018). Immunotherapy in colorectal cancer treatment: Actual landscape and future perspectives. Journal of Cancer Metastasis and Treatment, 4, 55.

Article  CAS  Google Scholar 

Coupez, D., Hulo, P., Touchefeu, Y., Bossard, C., & Bennouna, J. (2020). Pembrolizumab for the treatment of colorectal cancer. Expert Opinion on Biological Therapy, 20(3), 219–226.

Article  PubMed  CAS  Google Scholar 

Kasi, A., Handa, S., Bhatti, S., Umar, S., Bansal, A., & Sun, W. (2020). Molecular pathogenesis and classification of colorectal carcinoma. Current colorectal cancer reports, 16, 97–106.

Article  PubMed  PubMed Central  Google Scholar 

Sawayama, H., Miyamoto, Y., Ogawa, K., Yoshida, N., & Baba, H. (2020). Investigation of colorectal cancer in accordance with consensus molecular subtype classification. Annals of Gastroenterological Surgery, 4(5), 528–539.

Article  PubMed  PubMed Central  Google Scholar 

Franke, A. J., Skelton, W. P., IV., Starr, J. S., Parekh, H., Lee, J. J., Overman, M. J., et al. (2019). Immunotherapy for colorectal cancer: A review of current and novel therapeutic approaches. JNCI: Journal of the National Cancer Institute, 111(11), 1131–1141.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Sveen, A., Bruun, J., Eide, P. W., Eilertsen, I. A., Ramirez, L., Murumägi, A., et al. (2018). Colorectal cancer consensus molecular subtypes translated to preclinical models uncover potentially targetable cancer cell dependenciesdrug responses among consensus molecular subtypes of colorectal cancer. Clinical Cancer Research, 24(4), 794–806.

Article  PubMed  CAS  Google Scholar 

Jahanafrooz, Z., Mosafer, J., Akbari, M., Hashemzaei, M., Mokhtarzadeh, A., & Baradaran, B. (2020). Colon cancer therapy by focusing on colon cancer stem cells and their tumor microenvironment. Journal of cellular physiology, 235(5), 4153–4166.

Article  PubMed  CAS  Google Scholar 

Effendi, R., & Rey, I. (2020). Cancer stem cells and signaling pathways in colorectal cancer. The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy, 19(1), 37–41.

Article  Google Scholar 

Liu, J., Li, H., Shen, S., Sun, L., Yuan, Y., & Xing, C. (2018). Alternative splicing events implicated in carcinogenesis and prognosis of colorectal cancer. Journal of Cancer, 9(10), 1754.

Article  PubMed  PubMed Central  Google Scholar 

Karunanithi, S., Levi, L., DeVecchio, J., Karagkounis, G., Reizes, O., Lathia, J. D., et al. (2017). RBP4-STRA6 pathway drives cancer stem cell maintenance and mediates high-fat diet-induced colon carcinogenesis. Stem cell reports, 9(2), 438–450.

Article  PubMed  PubMed Central  CAS  Google Scholar 

La Vecchia, S., & Sebastián, C. (2020). Metabolic pathways regulating colorectal cancer initiation and progression. In Seminars in cell & developmental biology, 98, 63–70. Elsevier.

Article  Google Scholar 

Ferlizza, E., Solmi, R., Sgarzi, M., Ricciardiello, L., & Lauriola, M. (2021). The roadmap of colorectal cancer screening. Cancers, 13(5), 1101.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Picard, E., Verschoor, C. P., Ma, G. W., & Pawelec, G. (2020). Relationships between immune landscapes, genetic subtypes and responses to immunotherapy in colorectal cancer. Frontiers in immunology, 11, 369.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Garza-Treviño, E. N., Said-Fernández, S. L., & Martínez-Rodríguez, H. G. (2015). Understanding the colon cancer stem cells and perspectives on treatment. Cancer cell international, 15(1), 1–9.

Article  Google Scholar 

Puré, E., & Blomberg, R. (2018). Pro-tumorigenic roles of fibroblast activation protein in cancer: Back to the basics. Oncogene, 37(32), 4343–4357.

Article  PubMed  PubMed Central  Google Scholar 

Burnett-Hartman, A. N., Newcomb, P. A., & Potter, J. D. (2008). Infectious agents and colorectal cancer: A review of Helicobacter pylori, Streptococcus bovis, JC virus, and human papillomavirus. Cancer Epidemiology Biomarkers & Prevention, 17(11), 2970–2979.

Article  Google Scholar 

Dejea, C. M., Wick, E. C., Hechenbleikner, E. M., White, J. R., Mark Welch, J. L., Rossetti, B. J., et al. (2014). Microbiota organization is a distinct feature of proximal colorectal cancers. Proceedings of the National Academy of Sciences, 111(51), 18321–18326.

Article  CAS  Google Scholar 

Jinesh, G., Sambandam, V., Vijayaraghavan, S., Balaji, K., & Mukherjee, S. (2018). Molecular genetics and cellular events of K-Ras-driven tumorigenesis. Oncogene, 37(7), 839–846.

Article  PubMed  CAS  Google Scholar 

Fu, X., Wang, X., Duanmu, J., Li, T., & Jiang, Q. (2021). KRAS mutations are negatively correlated with immunity in colon cancer. Aging (Albany NY), 13(1), 750.

Article  CAS  Google Scholar 

El Agy, F., El Bardai, S., El Otmani, I., Benbrahim, Z., Karim, I. M. H., Mazaz, K., et al. (2021). Mutation status and prognostic value of KRAS and NRAS mutations in Moroccan colon cancer patients: A first report. PLoS ONE, 16(3), e0248522.

Article  PubMed  Google Scholar 

Patel, S., Alam, A., Pant, R., & Chattopadhyay, S. (2019). Wnt signaling and its significance within the tumor microenvironment: Novel therapeutic insights. Frontiers in immunology, 10, 2872.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Chen, J., Ding, Z.-Y., Li, S., Liu, S., Xiao, C., Li, Z., et al. (2021). Targeting transforming growth factor-β signaling for enhanced cancer chemotherapy. Theranostics, 11(3), 1345.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Dandawate, P., Subramaniam, D., Panovich, P., Standing, D., Krishnamachary, B., Kaushik, G., et al. (2020). Cucurbitacin B and I inhibits colon cancer growth by targeting the Notch signaling pathway. Scientific reports, 10(1), 1–15.

Article  Google Scholar 

Luan, X. F., Wang, L., & Gai, X. F. (2021). The miR-28-5p-CAMTA2 axis regulates colon cancer progression via Wnt/β-catenin signaling. Journal of Cellular Biochemistry, 122(9), 945–957.

Article  PubMed  CAS  Google Scholar 

Hernández-Luna, M. A., Lopez-Briones, S., & Luria-Pérez, R. (2019). The four horsemen in colon cancer. Journal of Oncology, 2019.

Beyaz, S., Mana, M. D., Roper, J., Kedrin, D., Saadatpour, A., Hong, S.-J., et al. (2016). High-fat diet enhances stemness and tumorigenicity of intestinal progenitors. Nature, 531(7592), 53–58.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Sabatino, S. A., Thompson, T. D., White, M. C., Shapiro

Comments (0)

No login
gif