IGF2 is upregulated by its antisense RNA to potentiate pancreatic cancer progression

Bhan A, Soleimani M, Mandal SS (2017) Long noncoding RNA and cancer: a new paradigm. Cancer Res 77:3965–3981. https://doi.org/10.1158/0008-5472.Can-16-2634

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chan JJ, Tay Y (2018) Noncoding RNA: RNA regulatory networks in cancer. Int J Mol Sci 19(5):1310. https://doi.org/10.3390/ijms19051310

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chen C, Ding P, Yan W, Wang Z, Lan Y, Yan X, Li T, Han J (2023) Pharmacological roles of lncRNAs in diabetic retinopathy with a focus on oxidative stress and inflammation. Biochem Pharmacol 214:115643. https://doi.org/10.1016/j.bcp.2023.115643

Article  CAS  PubMed  Google Scholar 

Chen W, Wang F, Zhang J, Li C, Hong L (2022) LINC01087 indicates a poor prognosis of glioma patients with preoperative MRI. Funct Integr Genomics 22:55–64. https://doi.org/10.1007/s10142-021-00812-w

Article  CAS  PubMed  Google Scholar 

Cheng F, Wang L, Yi S (2022) Long non-coding RNA SNHG1/microRNA-195-5p/Yes-associated protein axis affects the proliferation and metastasis of gastric cancer via the Hippo signaling pathway. Funct Integr Genomics 22:1043–1055. https://doi.org/10.1007/s10142-022-00876-2

Article  CAS  PubMed  Google Scholar 

Dong Y, Li J, Han F, Chen H, Zhao X, Qin Q, Shi R, Liu J (2015) High IGF2 expression is associated with poor clinical outcome in human ovarian cancer. Oncol Rep 34:936–942. https://doi.org/10.3892/or.2015.4048

Article  CAS  PubMed  Google Scholar 

Feng Y, Yang Y, Fan C, Di S, Hu W, Jiang S, Li T, Ma Z, Chao D, Feng X, Xin Z, Pang S, Li X, Yan X (2016) Pterostilbene inhibits the growth of human esophageal cancer cells by regulating endoplasmic reticulum stress. Cell Physiol Biochem 38:1226–1244. https://doi.org/10.1159/000443071

Article  CAS  PubMed  Google Scholar 

Gao W, Gu Y, Li Z, Cai H, Peng Q, Tu M, Kondo Y, Shinjo K, Zhu Y, Zhang J, Sekido Y, Han B, Qian Z, Miao Y (2015) miR-615-5p is epigenetically inactivated and functions as a tumor suppressor in pancreatic ductal adenocarcinoma. Oncogene 34:1629–1640. https://doi.org/10.1038/onc.2014.101

Article  CAS  PubMed  Google Scholar 

Georg J, Hess WR (2018) Widespread antisense transcription in prokaryotes. Microbiol Spectr 6. https://doi.org/10.1128/microbiolspec.RWR-0029-2018

Han Q, Li J, Xiong J, Song Z (2020) Long noncoding RNA LINC00514 accelerates pancreatic cancer progression by acting as a ceRNA of miR-28-5p to upregulate Rap1b expression. J Exp Clin Cancer Res 39:151. https://doi.org/10.1186/s13046-020-01660-5

Article  CAS  PubMed  PubMed Central  Google Scholar 

Harris LK, Westwood M (2012) Biology and significance of signalling pathways activated by IGF-II. Growth Factors 30:1–12. https://doi.org/10.3109/08977194.2011.640325

Article  CAS  PubMed  Google Scholar 

Hu X, Wu J, Xu J (2023) UCA1 executes an oncogenic role in pancreatic cancer by regulating miR-582-5p/BRCC3. Front Oncol 13:1133200. https://doi.org/10.3389/fonc.2023.1133200

Article  CAS  PubMed  PubMed Central  Google Scholar 

Huang GS, Brouwer-Visser J, Ramirez MJ, Kim CH, Hebert TM, Lin J, Arias-Pulido H, Qualls CR, Prossnitz ER, Goldberg GL, Smith HO, Horwitz SB (2010) Insulin-like growth factor 2 expression modulates Taxol resistance and is a candidate biomarker for reduced disease-free survival in ovarian cancer. Clin Cancer Res 16:2999–3010. https://doi.org/10.1158/1078-0432.Ccr-09-3233

Article  CAS  PubMed  PubMed Central  Google Scholar 

Huang H, Li X, Zhang X, Li Z, Han D, Gao W, Liu L, Peng C, Zhu H, Yu X (2022) DSCR9/miR-21-5p axis inhibits pancreatic cancer proliferation and resistance to gemcitabine via BTG2 signaling. Acta Biochim Biophys Sin 54:1775–1788. https://doi.org/10.3724/abbs.2022194

Article  CAS  PubMed  PubMed Central  Google Scholar 

Jin X, Feng J, Cheng X (2022) LncRNA IGF2-AS promotes endometriosis progression through targeting miR-370-3p/IGF2 axis and activating PI3K/AKT/mTOR signaling pathway. J Assist Reprod Genet 39:2699–2710. https://doi.org/10.1007/s10815-022-02638-2

Article  PubMed  Google Scholar 

Kopp F, Mendell JT (2018) Functional classification and experimental dissection of long noncoding RNAs. Cell 172:393–407. https://doi.org/10.1016/j.cell.2018.01.011

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lee EK, Kim HH, Kuwano Y, Abdelmohsen K, Srikantan S, Subaran SS, Gleichmann M, Mughal MR, Martindale JL, Yang X, Worley PF, Mattson MP, Gorospe M (2010) hnRNP C promotes APP translation by competing with FMRP for APP mRNA recruitment to P bodies. Nat Struct Mol Biol 17:732–739. https://doi.org/10.1038/nsmb.1815

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li S, Dong R, Kang Z, Li H, Wu X, Li T (2023a) Exosomes: another intercellular lipometabolic communication mediators in digestive system neoplasms? Cytokine Growth Factor Rev 73:93–100. https://doi.org/10.1016/j.cytogfr.2023.06.005

Article  CAS  PubMed  Google Scholar 

Li S, Jiang F, Chen F, Deng Y, Huang H (2023b) Silencing long noncoding RNA LINC01133 suppresses pancreatic cancer through regulation of microRNA-1299-dependent IGF2BP3.e23534. https://doi.org/10.1002/jbt.23534

Li T, Yang Z (2018) Melatonin: does it have utility in the treatment of haematological neoplasms? Br J Pharmacol 175:3251–3262. https://doi.org/10.1111/bph.13966

Article  CAS  PubMed  Google Scholar 

Li Y, Zhang Z, Yang Y, Ma J (2020) Long Noncoding RNA HOX Transcript antisense RNA gene rs17720428 single nucleotide polymorphism is associated with gastric cancer risk and prognosis. Genet Test Mol Biomark 24:38–46. https://doi.org/10.1089/gtmb.2019.0140

Article  CAS  Google Scholar 

Liu SB, Zhou LB, Wang HF, Li G, Xie QP, Hu B (2020) Loss of IGF2R indicates a poor prognosis and promotes cell proliferation and tumorigenesis in bladder cancer via AKT signaling pathway. Neoplasma 67:129–136. https://doi.org/10.4149/neo_2019_190206N108

Article  CAS  PubMed  Google Scholar 

Livingstone C (2013) IGF2 and cancer. Endocr Relat Cancer 20:R321–R339. https://doi.org/10.1530/erc-13-0231

Article  CAS  PubMed  Google Scholar 

Ma Z, Fan C, Yang Y, Di S, Hu W, Li T, Zhu Y, Han J, Xin Z, Wu G, Zhao J, Li X, Yan X (2016) Thapsigargin sensitizes human esophageal cancer to TRAIL-induced apoptosis via AMPK activation. Sci Rep 6:35196. https://doi.org/10.1038/srep35196

Article  CAS  PubMed  PubMed Central  Google Scholar 

Martinez-Quetglas I, Pinyol R, Dauch D, Torrecilla S, Tovar V, Moeini A, Alsinet C, Portela A, Rodriguez-Carunchio L, Solé M, Lujambio A, Villanueva A, Thung S, Esteller M, Zender L, Llovet JM (2016) IGF2 is up-regulated by epigenetic mechanisms in hepatocellular carcinomas and is an actionable oncogene product in experimental models. Gastroenterology 151:1192–1205. https://doi.org/10.1053/j.gastro.2016.09.001

Article  CAS  PubMed  Google Scholar 

Mercer TR, Dinger ME, Mattick JS (2009) Long non-coding RNAs: insights into functions. Nat Rev Genet 10:155–159. https://doi.org/10.1038/nrg2521

Article  CAS  PubMed  Google Scholar 

Ou JM, Lian WS, Qiu MK, Dai YX, Dong Q, Shen J, Dong P, Wang XF, Liu YB, Quan ZW, Fei ZW (2014) Knockdown of IGF2R suppresses proliferation and induces apoptosis in hemangioma cells in vitro and in vivo. Int J Oncol 45:1241–1249. https://doi.org/10.3892/ijo.2014.2512

Article  CAS  PubMed  Google Scholar 

Pastushenko I, Blanpain C (2019) EMT transition states during tumor progression and metastasis. Trends Cell Biol 29:212–226. https://doi.org/10.1016/j.tcb.2018.12.001

Article  CAS  PubMed  Google Scholar 

Reymond N, d'Água BB, Ridley AJ (2013) Crossing the endothelial barrier during metastasis. Nat Rev Cancer 13:858–870. https://doi.org/10.1038/nrc3628

Article  CAS  PubMed  Google Scholar 

Schagdarsurengin U, Lammert A, Schunk N, Sheridan D, Gattenloehner S, Steger K, Wagenlehner F, Dansranjavin T (2017) Impairment of IGF2 gene expression in prostate cancer is triggered by epigenetic dysregulation of IGF2-DMR0 and its interaction with KLF4. Cell Commun Signal 15:40. https://doi.org/10.1186/s12964-017-0197-7

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sferruzzi-Perri AN, Sandovici I, Constancia M, Fowden AL (2017) Placental phenotype and the insulin-like growth factors: resource allocation to fetal growth. J Physiol 595:5057–5093. https://doi.org/10.1113/jp273330

Article  CAS  PubMed  PubMed Central  Google Scholar 

Shen XM, Han S, Liu N, Xu HQ, Yan CX, Yu CJ (2021) LINC00887 aggravates the malignant progression of glioma via upregulating CCND1. Eur Rev Med Pharmacol Sci 25:1928–1935. https://doi.org/10.26355/eurrev_202102_25091

Article  PubMed  Google Scholar 

Shi F, Li T, Liu Z, Qu K, Shi C, Li Y, Qin Q, Cheng L, Jin X, Yu T, Di W, Que J, Xia H, She J (2018) FOXO1: another avenue for treating digestive malignancy? Semin Cancer Biol 50:124–131. https://doi.org/10.1016/j.semcancer.2017.09.009

Article  CAS  PubMed 

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