Andersson C, Vasan RS (2018) Epidemiology of cardiovascular disease in young individuals. Nat Rev Cardiol 15:230–240. https://doi.org/10.1038/nrcardio.2017.154
Steven S, Frenis K, Oelze M, Kalinovic S, Kuntic M, Bayo Jimenez MT, Vujacic-Mirski K, Helmstädter J, Kröller-Schön S, Münzel T, Daiber A (2019) Vascular inflammation and oxidative stress: major triggers for cardiovascular disease. Oxid Med Cell Longev 2019:7092151. https://doi.org/10.1155/2019/7092151
Article CAS PubMed PubMed Central Google Scholar
Soppert J, Lehrke M, Marx N, Jankowski J, Noels H (2020) Lipoproteins and lipids in cardiovascular disease: from mechanistic insights to therapeutic targeting. Adv Drug Deliv Rev 159:4–33. https://doi.org/10.1016/j.addr.2020.07.019
Article CAS PubMed Google Scholar
Sunkara A, Raizner A (2019) Supplemental vitamins and minerals for cardiovascular disease prevention and treatment. Methodist Debakey Cardiovasc J 15:179–184. https://doi.org/10.14797/mdcj-15-3-179
Article PubMed PubMed Central Google Scholar
Zhao D, Liu J, Wang M, Zhang X, Zhou M (2019) Epidemiology of cardiovascular disease in China: current features and implications. Nat Rev Cardiol 16:203–212. https://doi.org/10.1038/s41569-018-0119-4
Zhou Y, Song K, Tu B, Sun H, Ding JF, Luo Y, Sha JM, Li R, Zhang Y, Zhao JY, Tao H (2022) METTL3 boosts glycolysis and cardiac fibroblast proliferation by increasing AR methylation. Int J Biol Macromol 223:899–915. https://doi.org/10.1016/j.ijbiomac.2022.11.042
Article CAS PubMed Google Scholar
Xie Y, Shi X, Sheng K, Han G, Li W, Zhao Q, Jiang B, Feng J, Li J, Gu Y (2019) PI3K/Akt signaling transduction pathway, erythropoiesis and glycolysis in hypoxia (Review). Mol Med Rep 19:783–791. https://doi.org/10.3892/mmr.2018.9713
Article CAS PubMed Google Scholar
Chang YC, Kim CH (2022) Molecular research of glycolysis. Int J Mol Sci. https://doi.org/10.3390/ijms23095052
Article PubMed PubMed Central Google Scholar
Feng J, Li J, Wu L, Yu Q, Ji J, Wu J, Dai W, Guo C (2020) Emerging roles and the regulation of aerobic glycolysis in hepatocellular carcinoma. J Exp Clin Cancer Res 39:126. https://doi.org/10.1186/s13046-020-01629-4
Article CAS PubMed PubMed Central Google Scholar
TeSlaa T, Bartman CR, Jankowski CSR, Zhang Z, Xu X, Xing X, Wang L, Lu W, Hui S, Rabinowitz JD (2021) The source of glycolytic intermediates in mammalian tissues. Cell Metab 33:367-378.e5. https://doi.org/10.1016/j.cmet.2020.12.020
Article CAS PubMed PubMed Central Google Scholar
Badolia R, Ramadurai DKA, Abel ED, Ferrin P, Taleb I, Shankar TS, Krokidi AT, Navankasattusas S, McKellar SH, Yin M, Kfoury AG, Wever-Pinzon O, Fang JC, Selzman CH, Chaudhuri D, Rutter J, Drakos SG (2020) The role of nonglycolytic glucose metabolism in myocardial recovery upon mechanical unloading and circulatory support in chronic heart failure. Circulation 142:259–274. https://doi.org/10.1161/circulationaha.119.044452
Article CAS PubMed PubMed Central Google Scholar
Tran DH, Wang ZV (2019) Glucose metabolism in cardiac hypertrophy and heart failure. J Am Heart Assoc 8:e012673. https://doi.org/10.1161/jaha.119.012673
Article CAS PubMed PubMed Central Google Scholar
Brahma MK, Pepin ME, Wende AR (2017) My sweetheart is broken: role of glucose in diabetic cardiomyopathy. Diabetes Metab J 41:1–9. https://doi.org/10.4093/dmj.2017.41.1.1
Lopaschuk GD, Karwi QG, Tian R, Wende AR, Abel ED (2021) Cardiac energy metabolism in heart failure. Circ Res 128:1487–1513. https://doi.org/10.1161/circresaha.121.318241
Article CAS PubMed PubMed Central Google Scholar
Bertero E, Maack C (2018) Metabolic remodelling in heart failure. Nat Rev Cardiol 15:457–470. https://doi.org/10.1038/s41569-018-0044-6
Article CAS PubMed Google Scholar
Calmettes G, Ribalet B, John S, Korge P, Ping P, Weiss JN (2015) Hexokinases and cardioprotection. J Mol Cell Cardiol 78:107–115. https://doi.org/10.1016/j.yjmcc.2014.09.020
Article CAS PubMed Google Scholar
John S, Weiss JN, Ribalet B (2011) Subcellular localization of hexokinases I and II directs the metabolic fate of glucose. PLoS ONE 6:e17674. https://doi.org/10.1371/journal.pone.0017674
Article CAS PubMed PubMed Central Google Scholar
Depre C, Vanoverschelde JL, Taegtmeyer H (1999) Glucose for the heart. Circulation 99:578–588. https://doi.org/10.1161/01.cir.99.4.578
Article CAS PubMed Google Scholar
Wu R, Wyatt E, Chawla K, Tran M, Ghanefar M, Laakso M, Epting CL, Ardehali H (2012) Hexokinase II knockdown results in exaggerated cardiac hypertrophy via increased ROS production. EMBO Mol Med 4:633–646. https://doi.org/10.1002/emmm.201200240
Article CAS PubMed PubMed Central Google Scholar
Rabbani N, Xue M, Thornalley PJ (2022) Hexokinase-2-linked glycolytic overload and unscheduled glycolysis-driver of insulin resistance and development of vascular complications of diabetes. Int J Mol Sci. https://doi.org/10.3390/ijms23042165
Article PubMed PubMed Central Google Scholar
Rabbani N, Thornalley PJ (2019) Hexokinase-2 glycolytic overload in diabetes and ischemia-reperfusion injury. Trends Endocrinol Metab 30:419–431. https://doi.org/10.1016/j.tem.2019.04.011
Article CAS PubMed Google Scholar
Dambrova M, Zuurbier CJ, Borutaite V, Liepinsh E, Makrecka-Kuka M (2021) Energy substrate metabolism and mitochondrial oxidative stress in cardiac ischemia/reperfusion injury. Free Radic Biol Med 165:24–37. https://doi.org/10.1016/j.freeradbiomed.2021.01.036
Article CAS PubMed Google Scholar
Lemasters JJ, Holmuhamedov E (2006) Voltage-dependent anion channel (VDAC) as mitochondrial governator–thinking outside the box. Biochim Biophys Acta 1762:181–190. https://doi.org/10.1016/j.bbadis.2005.10.006
Article CAS PubMed Google Scholar
Pasdois P, Parker JE, Halestrap AP (2012) Extent of mitochondrial hexokinase II dissociation during ischemia correlates with mitochondrial cytochrome c release, reactive oxygen species production, and infarct size on reperfusion. J Am Heart Assoc 2:e005645. https://doi.org/10.1161/jaha.112.005645
Kim KW, Kim SW, Lim S, Yoo KJ, Hwang KC, Lee S (2021) Neutralization of hexokinase 2-targeting miRNA attenuates the oxidative stress-induced cardiomyocyte apoptosis. Clin Hemorheol Microcirc 78:57–68. https://doi.org/10.3233/ch-200924
Article CAS PubMed Google Scholar
Halestrap AP, Pereira GC, Pasdois P (2015) The role of hexokinase in cardioprotection - mechanism and potential for translation. Br J Pharmacol 172:2085–2100. https://doi.org/10.1111/bph.12899
Article CAS PubMed Google Scholar
Nederlof R, Eerbeek O, Hollmann MW, Southworth R, Zuurbier CJ (2014) Targeting hexokinase II to mitochondria to modulate energy metabolism and reduce ischaemia-reperfusion injury in heart. Br J Pharmacol 171:2067–2079. https://doi.org/10.1111/bph.12363
Article CAS PubMed PubMed Central Google Scholar
Guo L (2022) Mitochondrial ATP synthase inhibitory factor 1 interacts with the p53-cyclophilin D complex and promotes opening of the permeability transition pore. J Biol Chem 298:101858. https://doi.org/10.1016/j.jbc.2022.101858
Article CAS PubMed PubMed Central Google Scholar
Guo L (2021) Mitochondria and the permeability transition pore in cancer metabolic reprogramming. Biochem Pharmacol 188:114537. https://doi.org/10.1016/j.bcp.2021.114537
Article CAS PubMed Google Scholar
Ciscato F, Ferrone L, Masgras I, Laquatra C, Rasola A (2021) Hexokinase 2 in Cancer: A Prima Donna Playing Multiple Characters. Int J Mol Sci. https://doi.org/10.3390/ijms22094716
Article PubMed PubMed Central Google Scholar
Murry CE, Jennings RB, Reimer KA (1986) Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. Circulation 74:1124–1136. https://doi.org/10.1161/01.cir.74.5.1124
Article CAS PubMed Google Scholar
Tian M, Xie Y, Meng Y, Ma W, Tong Z, Yang X, Lai S, Zhou Y, He M, Liao Z (2019) Resveratrol protects cardiomyocytes against anoxia/reoxygenation via dephosphorylation of VDAC1 by Akt-GSK3 β pathway. Eur J Pharmacol 843:80–87. https://doi.org/10.1016/j.ejphar.2018.11.016
留言 (0)