Alleviated cerebral infarction in male mice lacking all nitric oxide synthase isoforms after middle cerebral artery occlusion

Goldstein L. Ischemic cerebrovascular disease. In: Crow M, Davidson N, Drazen J, Griggs R, Landry D, Levinson W, Rustgi A, Scheld W, Sopiegel A, editors. Goldman-cecil medicine. 26th ed.: Elsevier; 2020.

Smith W, Johnston S, Hemphili J. Ischemic stroke. In: Loscalzo J, AS F, Kasper D, Hauser S, Longo D, Jameson J, editors. Harrison's principles of internal medicine. 21st ed.: Mc Graw Hill; 2022. p. 3335–48.

Brindicci C, Kharitonov SA, Ito M, Elliott MW, Hogg JC, Barnes PJ, Ito K. Nitric oxide synthase isoenzyme expression and activity in peripheral lung tissue of patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2010;181(1):21–30. https://doi.org/10.1164/rccm.200904-0493OC.

Article  CAS  PubMed  Google Scholar 

Tsutsui M, Shimokawa H, Otsuji Y, Yanagihara N. Pathophysiological relevance of NO signaling in the cardiovascular system: novel insight from mice lacking all NO synthases. Pharmacol Ther. 2010;128(3):499–508. https://doi.org/10.1016/j.pharmthera.2010.08.010.

Article  CAS  PubMed  Google Scholar 

Tsutsui M, Tanimoto A, Tamura M, Mukae H, Yanagihara N, Shimokawa H, Otsuji Y. Significance of nitric oxide synthases: lessons from triple nitric oxide synthases null mice. J Pharmacol Sci. 2015;127(1):42–52. https://doi.org/10.1016/j.jphs.2014.10.002.

Article  CAS  PubMed  Google Scholar 

Huang Z, Huang PL, Ma J, Meng W, Ayata C, Fishman MC, Moskowitz MA. Enlarged infarcts in endothelial nitric oxide synthase knockout mice are attenuated by nitro-l-arginine. J Cereb Blood Flow Metab. 1996;16(5):981–7. https://doi.org/10.1097/00004647-199609000-00023.

Article  CAS  PubMed  Google Scholar 

Huang Z, Huang PL, Panahian N, Dalkara T, Fishman MC, Moskowitz MA. Effects of cerebral ischemia in mice deficient in neuronal nitric oxide synthase. Science. 1994;265(5180):1883–5. https://doi.org/10.1126/science.7522345.

Article  CAS  PubMed  Google Scholar 

Iadecola C, Zhang F, Casey R, Nagayama M, Ross ME. Delayed reduction of ischemic brain injury and neurological deficits in mice lacking the inducible nitric oxide synthase gene. J Neurosci. 1997;17(23):9157–64.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yamamoto S, Golanov EV, Berger SB, Reis DJ. Inhibition of nitric oxide synthesis increases focal ischemic infarction in rat. J Cereb Blood Flow Metab. 1992;12(5):717–26. https://doi.org/10.1038/jcbfm.1992.102.

Article  CAS  PubMed  Google Scholar 

Buisson A, Plotkine M, Boulu RG. The neuroprotective effect of a nitric oxide inhibitor in a rat model of focal cerebral ischaemia. Br J Pharmacol. 1992;106(4):766–7. https://doi.org/10.1111/j.1476-5381.1992.tb14410.x.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Suda O, Tsutsui M, Morishita T, Tanimoto A, Horiuchi M, Tasaki H, Huang PL, Sasaguri Y, Yanagihara N, Nakashima Y. Long-term treatment with N(omega)-nitro-L-arginine methyl ester causes arteriosclerotic coronary lesions in endothelial nitric oxide synthase-deficient mice. Circulation. 2002;106(13):1729–35. https://doi.org/10.1161/01.cir.0000029749.16101.44.

Article  CAS  PubMed  Google Scholar 

Suda O, Tsutsui M, Morishita T, Tasaki H, Ueno S, Nakata S, Tsujimoto T, Toyohira Y, Hayashida Y, Sasaguri Y, Ueta Y, Nakashima Y, Yanagihara N. Asymmetric dimethylarginine produces vascular lesions in endothelial nitric oxide synthase-deficient mice: involvement of renin-angiotensin system and oxidative stress. Arterioscler Thromb Vasc Biol. 2004;24(9):1682–8. https://doi.org/10.1161/01.ATV.0000136656.26019.6e.

Article  CAS  PubMed  Google Scholar 

Morishita T, Tsutsui M, Shimokawa H, Sabanai K, Tasaki H, Suda O, Nakata S, Tanimoto A, Wang KY, Ueta Y, Sasaguri Y, Nakashima Y, Yanagihara N. Nephrogenic diabetes insipidus in mice lacking all nitric oxide synthase isoforms. Proc Natl Acad Sci U S A. 2005;102(30):10616–21. https://doi.org/10.1073/pnas.0502236102.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Laubach VE, Shesely EG, Smithies O, Sherman PA. Mice lacking inducible nitric oxide synthase are not resistant to lipopolysaccharide-induced death. Proc Natl Acad Sci U S A. 1995;92(23):10688–92. https://doi.org/10.1073/pnas.92.23.10688.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Maeda K, Hata R, Hossmann KA. Differences in the cerebrovascular anatomy of C57black/6 and SV129 mice. NeuroReport. 1998;9(7):1317–9. https://doi.org/10.1097/00001756-199805110-00012.

Article  CAS  PubMed  Google Scholar 

Coyle P, Jokelainen PT. Dorsal cerebral arterial collaterals of the rat. Anat Rec. 1982;203(3):397–404. https://doi.org/10.1002/ar.1092030309.

Article  CAS  PubMed  Google Scholar 

Coyle P. Spatial relations of dorsal anastomoses and lesion border after middle cerebral artery occlusion. Stroke. 1987;18(6):1133–40. https://doi.org/10.1161/01.str.18.6.1133.

Article  CAS  PubMed  Google Scholar 

Longa EZ, Weinstein PR, Carlson S, Cummins R. Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke. 1989;20(1):84–91. https://doi.org/10.1161/01.str.20.1.84.

Article  CAS  PubMed  Google Scholar 

Hata R, Mies G, Wiessner C, Fritze K, Hesselbarth D, Brinker G, Hossmann KA. A reproducible model of middle cerebral artery occlusion in mice: hemodynamic, biochemical, and magnetic resonance imaging. J Cereb Blood Flow Metab. 1998;18(4):367–75. https://doi.org/10.1097/00004647-199804000-00004.

Article  CAS  PubMed  Google Scholar 

Manley GT, Fujimura M, Ma T, Noshita N, Filiz F, Bollen AW, Chan P, Verkman AS. Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic stroke. Nat Med. 2000;6(2):159–63. https://doi.org/10.1038/72256.

Article  CAS  PubMed  Google Scholar 

Swanson RA, Morton MT, Tsao-Wu G, Savalos RA, Davidson C, Sharp FR. A semiautomated method for measuring brain infarct volume. J Cereb Blood Flow Metab. 1990;10(2):290–3. https://doi.org/10.1038/jcbfm.1990.47.

Article  CAS  PubMed  Google Scholar 

Drel VR, Pacher P, Stevens MJ, Obrosova IG. Aldose reductase inhibition counteracts nitrosative stress and poly(ADP-ribose) polymerase activation in diabetic rat kidney and high-glucose-exposed human mesangial cells. Free Radic Biol Med. 2006;40(8):1454–65. https://doi.org/10.1016/j.freeradbiomed.2005.12.034.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kina-Tanada M, Sakanashi M, Tanimoto A, Kaname T, Matsuzaki T, Noguchi K, Uchida T, Nakasone J, Kozuka C, Ishida M, Kubota H, Taira Y, Totsuka Y, Kina SI, Sunakawa H, Omura J, Satoh K, Shimokawa H, Yanagihara N, Maeda S, Ohya Y, Matsushita M, Masuzaki H, Arasaki A, Tsutsui M. Long-term dietary nitrite and nitrate deficiency causes the metabolic syndrome, endothelial dysfunction and cardiovascular death in mice. Diabetologia. 2017;60(6):1138–51. https://doi.org/10.1007/s00125-017-4259-6.

Article  CAS  PubMed  Google Scholar 

Ogoshi T, Tsutsui M, Kido T, Sakanashi M, Naito K, Oda K, Ishimoto H, Yamada S, Wang KY, Toyohira Y, Izumi H, Masuzaki H, Shimokawa H, Yanagihara N, Yatera K, Mukae H. Protective role of myelocytic nitric oxide synthases against hypoxic pulmonary hypertension in mice. Am J Respir Crit Care Med. 2018;198(2):232–44. https://doi.org/10.1164/rccm.201709-1783OC.

Article  CAS  PubMed  Google Scholar 

Li Y, Zhang J. Animal models of stroke. Animal Model Exp Med. 2021;4(3):204–19. https://doi.org/10.1002/ame2.12179.

Article  PubMed  PubMed Central  Google Scholar 

Hawk T, Zhang YQ, Rajakumar G, Day AL, Simpkins JW. Testosterone increases and estradiol decreases middle cerebral artery occlusion lesion size in male rats. Brain Res. 1998;796(1–2):296–8. https://doi.org/10.1016/s0006-8993(98)00327-8.

Article  CAS  PubMed  Google Scholar 

Wang C, Gong B, Bushel PR, Thierry-Mieg J, Thierry-Mieg D, Xu J, Fang H, Hong H, Shen J, Su Z, Meehan J, Li X, Yang L, Li H, Labaj PP, Kreil DP, Megherbi D, Gaj S, Caiment F, van Delft J, Kleinjans J, Scherer A, Devanarayan V, Wang J, Yang Y, Qian HR, Lancashire LJ, Bessarabova M, Nikolsky Y, Furlanello C, Chierici M, Albanese D, Jurman G, Riccadonna S, Filosi M, Visintainer R, Zhang KK, Li J, Hsieh JH, Svoboda DL, Fuscoe JC, Deng Y, Shi L, Paules RS, Auerbach SS, Tong W. The concordance between RNA-seq and microarray data depends on chemical treatment and transcript abundance. Nat Biotechnol. 2014;32(9):926–32. https://doi.org/10.1038/nbt.3001.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Jelinek M, Jurajda M, Duris K. Oxidative stress in the brain: basic concepts and treatment strategies in stroke. Antioxidants (Basel). 2021. https://doi.org/10.3390/antiox10121886.

Article  PubMed  Google Scholar 

Khoshnam SE, Winlow W, Farzaneh M, Farbood Y, Moghaddam HF. Pathogenic mechanisms following ischemic stroke. Neurol Sci. 2017;38(7):1167–86. https://doi.org/10.1007/s10072-017-2938-1.

Article  PubMed  Google Scholar 

He Z, Ning N, Zhou Q, Khoshnam SE, Farzaneh M. Mitochondria as a therapeutic target for ischemic stroke. Free Radic Biol Med. 2020;146:45–58. https://doi.org/10.1016/j.freeradbiomed.2019.11.005.

Article  CAS  PubMed  Google Scholar 

Edaravone Acute Infarction Study G. Effect of a novel free radical scavenger, edaravone (MCI-186), on acute brain infarction. Randomized, placebo-controlled, double-blind study at multicenters. Cerebrovasc Dis. 2003;15(3):222–9. https://doi.org/10.1159/000069318.

留言 (0)

沒有登入
gif