Polygenic Risk Score-Based Association Analysis of Speech-in-Noise and Hearing Threshold Measures in Healthy Young Adults with Self-reported Normal Hearing

Carhart R, Tillman TW (1970) Interaction of competing speech signals with hearing losses. Arch Otolaryngol 91(3):273–279

Article  CAS  PubMed  Google Scholar 

Holmes E, Griffiths TD (2019) ‘Normal’ hearing thresholds and fundamental auditory grouping processes predict difficulties with speech-in-noise perception. Sci Rep 9(1):16771

Article  PubMed  PubMed Central  Google Scholar 

Shub DE, Makashay MJ, Brungart DS (2020) Predicting speech-in-noise deficits from the audiogram. Ear Hear 41(1):39–54

Article  PubMed  Google Scholar 

Beck HE, Zimmermann NE, McVicar TR, Vergopolan N, Berg A, Wood EF (2018) Present and future Köppen-Geiger climate classification maps at 1-km resolution. Scientific data 5(1):1–12

Article  Google Scholar 

Hind SE, Haines-Bazrafshan R, Benton CL, Brassington W, Towle B, Moore DR (2011) Prevalence of clinical referrals having hearing thresholds within normal limits. Int J Audiol 50(10):708–716

Article  PubMed  Google Scholar 

Hunter LL, Monson BB, Moore DR, Dhar S, Wright BA, Munro KJ,  Zadeh LM, Blankenship CM, Stiepan SM, Siegel JH (2020) Extended high frequency hearing and speech perception implications in adults and children. Hear Res 397:107922

Liberman MC, Kujawa SG (2017) Cochlear synaptopathy in acquired sensorineural hearing loss: manifestations and mechanisms. Hear Res 349:138–147

Article  PubMed  PubMed Central  Google Scholar 

Grose JH, Mamo SK, Hall JW III (2009) Age effects in temporal envelope processing: speech unmasking and auditory steady state responses. Ear Hear 30(5):568–575

Article  PubMed  PubMed Central  Google Scholar 

Darwin CJ (1997) Auditory grouping. Trends Cogn Sci 1(9):327–333

Article  CAS  PubMed  Google Scholar 

Dryden A, Allen HA, Henshaw H, Heinrich A (2017) The association between cognitive performance and speech-in-noise perception for adult listeners: a systematic literature review and meta-analysis. Trends in hearing 21:2331216517744675

Article  PubMed  PubMed Central  Google Scholar 

Astheimer LB, Sanders LD (2009) Listeners modulate temporally selective attention during natural speech processing. Biol Psychol 80(1):23–34

Article  PubMed  Google Scholar 

Bhatt IS, Washnik N, Torkamani A (2022) Suprathreshold auditory measures for detecting early-stage noise-induced hearing loss in young adults. J Am Acad Audiol 33(04):185–195

Article  PubMed  Google Scholar 

Jiang K, Armstrong NM, Agrawal Y, Gross AL, Schrack JA, Lin FR, Ferucci L, Resnick SM, Deal JA, Powell DS (2022) Associations of audiometric hearing and speech-in-noise performance with cognitive decline among older adults: the Baltimore Longitudinal Study of Aging (BLSA). Front Neurol 13:1029851

Stevenson JS, Clifton L, Kuźma E, Littlejohns TJ (2022) Speech-in-noise hearing impairment is associated with an increased risk of incident dementia in 82,039 UK Biobank participants. Alzheimers Dement 18(3):445–456

Article  PubMed  Google Scholar 

Brewer CC, Zalewski CK, King KA, Zobay O, Riley A, Ferguson MA, Bird JE, McCabe MM, Hood LJ, Drayna D, Griffith AJ, Morell RJ, Friedman TB, Moore DR (2016) Heritability of non-speech auditory processing skills. Euro J Human Gene 24(8):1137–1144

Article  Google Scholar 

Saidia AR, Ruel J, Bahloul A, Chaix B, Venail F, Wang J (2023) Current advances in gene therapies of genetic auditory neuropathy spectrum disorder. J Clin Med 12(3):738

Article  CAS  PubMed  PubMed Central  Google Scholar 

Choi JE, Seok JM, Ahn J, Ji YS, Lee KM, Hong SH, Choi BO, Moon IJ (2018) Hidden hearing loss in patients with Charcot-Marie-Tooth disease type 1A. Sci Rep 8(1):1–8

Google Scholar 

Pinar A, Hawi Z, Cummins T, Johnson B, Pauper M, Tong J, Tiego J, Finlay A, Klein M, Franke B, Fornito A, Bellgrove MA (2018) Genome-wide association study reveals novel genetic locus associated with intra-individual variability in response time. Trans Psychiat 8(1):207

Trampush JW, Yang MLZ, Yu J, Knowles E, Davies G, Liewald DC et al (2017) GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium. Mole Psychiat 22(3):336–345

Article  CAS  Google Scholar 

Torkamani A, Wineinger NE, Topol EJ (2018) The personal and clinical utility of polygenic risk scores. Nat Rev Genet 19(9):581–590

Article  CAS  PubMed  Google Scholar 

Chen SF, Dias R, Evans D, Salfati EL, Liu S, Wineinger NE, Torkamani A (2020) Genotype imputation and variability in polygenic risk score estimation. Genome medicine 12:1–13

Article  CAS  Google Scholar 

Choi SW, Mak TSH, O’Reilly PF (2020) Tutorial: a guide to performing polygenic risk score analyses. Nat Protoc 15(9):2759–2772

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lambert SA, Gil L, Jupp S, Ritchie SC, Xu Y, Buniello A et al (2021) The Polygenic Score Catalog as an open database for reproducibility and systematic evaluation. Nat Gene 53(4):420–425

Article  CAS  Google Scholar 

Marston NA, Pirruccello JP, Melloni GE, Koyama S, Kamanu FK, Weng LC et al (2023) Predictive utility of a coronary artery disease polygenic risk score in primary prevention. JAMA Cardiol 8(2):130–137

Article  PubMed  Google Scholar 

Tanigawa Y, Qian J, Venkataraman G, Justesen JM, Li R, Tibshirani R, Hastie T, Rivas MA (2022) Significant sparse polygenic risk scores across 813 traits in UK Biobank. PLoS Gene 18(3):e1010105

Dikilitas O, Schaid DJ, Kosel ML, Carroll RJ, Chute CG, Denny JA et al (2020) Predictive utility of polygenic risk scores for coronary heart disease in three major racial and ethnic groups. Am J Human Gene 106(5):707–716

Article  CAS  Google Scholar 

Janssens ACJ (2019) Validity of polygenic risk scores: are we measuring what we think we are? Hum Mol Genet 28(R2):R143–R150

Article  CAS  PubMed  PubMed Central  Google Scholar 

Noble W, Jensen NS, Naylor G, Bhullar N, Akeroyd MA (2013) A short form of the Speech, Spatial and Qualities of Hearing scale suitable for clinical use: the SSQ12. Int J Audiol 52(6):409–412

Article  PubMed  PubMed Central  Google Scholar 

Killion MC, Niquette PA, Gudmundsen GI, Revit LJ, Banerjee S (2004) Development of a quick speech-in-noise test for measuring signal-to-noise ratio loss in normal-hearing and hearing-impaired listeners. The Journal of the Acoustical Society of America 116(4):2395–2405

Article  PubMed  Google Scholar 

Wilson RH, McArdle RA, Smith SL (2007) An evaluation of the BKB-SIN, HINT, QuickSIN, and WIN materials on listeners with normal hearing and listeners with hearing loss. J Speech Lang Hear Res 50(4):844–856

Article  PubMed  Google Scholar 

Rubinacci S, Ribeiro DM, Hofmeister RJ, Delaneau O (2021) Efficient phasing and imputation of low-coverage sequencing data using large reference panels. Nat Genet 53(1):120–126

Article  CAS  PubMed  Google Scholar 

Morales J, Welter D, Bowler EH, Cerezo M, Harris LW, McMahon AC et al (2018) A standardized framework for representation of ancestry data in genomics studies, with application to the NHGRI-EBI GWAS Catalog. Genome Biol 19(1):1–10

Article  Google Scholar 

Wand H, Lambert SA, Tamburro C, Iacocca MA, O’Sullivan JW, Sillari C et al (2021) Improving reporting standards for polygenic scores in risk prediction studies. Nature 591(7849):211–219

Article  CAS  PubMed  PubMed Central  Google Scholar 

Purcell S, Neale B, Todd-Brown K, Thomas L, Ferreira MA, Bender D et al (2007) PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Human Gene 81(3):559–575

Article  CAS  Google Scholar 

Benjamini Y, Hochberg Y (1995) Controlling the false discovery rate: a practical and powerful approach to multiple testing. J Roy Stat Soc: Ser B (Methodol) 57(1):289–300

Google Scholar 

Dai H, Zhang Q, Much AA, Maor E, Segev A, Beinart R et al (2021) Global, regional, and national prevalence, incidence, mortality, and risk factors for atrial fibrillation, 1990–2017: results from the Global Burden of Disease Study 2017. Euro Heart J Qual Care Clin Out 7(6):574–582

Article  Google Scholar 

Joseph PG, Healey JS, Raina P, Connolly SJ, Ibrahim Q, Gupta R et al; PURE Investigators (2021) Global variations in the prevalence, treatment, and impact of atrial fibrillation in a multi-national cohort of 153 152 middle-aged individuals. Cardiovas Res 117(6):1523–1531

Wang W, Saczynski J, Lessard D, Mailhot T, Barton B, Waring ME et al (2019) Physical, cognitive, and psychosocial conditions in relation to anticoagulation satisfaction among elderly adults with atrial fibrillation: The SAGE-AF study. J Cardiovas Electrophysiol 30(11):2508–2515

Article  Google Scholar 

Wang WJ, Lessard D, Abu H, McManus DD, Mailhot T, Gurwitz JH, Goldberg RJ, Saczynski J (2020) Hearing loss and cognitive decline among older adults with atrial fibrillation: the SAGE-AF study. J Geriat Cardiol JGC 17(4):177–183

Google Scholar 

Maharani A, Dawes P, Nazroo J, Tampubolon G, Pendleton N, on behalf of SENSE‐Cog WP1 group (2018) Longitudinal relationship between hearing aid use and cognitive function in older Americans. J Am Geriat Soc 66(6):1130–1136

Lough M, Plack CJ (2022) Extended high-frequency audiometry in research and clinical practice. The Journal of the Acoustical Society of America 151(3):1944–1955

Article  CAS  PubMed  Google Scholar 

British Society of Audiology (2018) Recommended procedure. Pure-tone air-conduction and bone-conduction threshold audiometry with and without masking. https://www.thebsa.org.uk/resources/pure-tone-air-bone-conduction-threshold-audiometry-without-masking/ (Last viewed April 28, 2023)

Knopke S, Schubert A, Häussler SM, Gräbel S, Szczepek AJ, Olze H (2021) Improvement of working memory and processing speed in patients over 70 with bilateral hearing impairment following unilateral cochlear implantation. J Clin Med 10(15):3421

Article  PubMed  PubMed Central  Google Scholar 

Utoomprurkporn N, Hardy CJ, Stott J, Costafreda SG, Warren J, Bamiou DE (2020) “The dichotic digit test” as an index indicator for hearing problem in dementia: systematic review and meta-analysis. J Am Acad Audiol 31(09):646–655

Article  PubMed  Google Scholar 

Loughrey DG, Kelly ME, Kelley GA, Brennan S, Lawlor BA (2018) Association of age-related hearing loss with cognitive function, cognitive impairment, and dementia: a systematic review and meta-analysis. JAMA Otolaryngol Head Neck Surg 144(2):115–126

Article  PubMed 

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