A. M. Fjell, M. H. Sneve, H. Grydeland, et al., “The disconnected brain and executive function decline in aging,” Cereb. Cortex, 27, No. 3, 2303–2317 (2017), https://doi.org/10.1093/cercor/bhw082.
A. Miyake, N. P. Friedman, M. J. Emerson, et al., “The unity and diversity of executive functions and their contributions to complex “Frontal Lobe” tasks: a latent variable analysis,” Cogn. Psychol., 41, No. 1, 49–100 (2000), https://doi.org/10.1006/cogp.1999.0734.
CAS Article PubMed Google Scholar
L. R. Clark, D. M. Schiehser, G. H. Weissberger, et al., “Specific measures of executive function predict cognitive decline in older adults,” J. Int. Neuropsychol. Soc., 18, No. 1, 118–127 (2012), https://doi.org/10.1017/S1355617711001524.
G. C. Rowe, A. Safdar, and Z. Arany, “Running forward: new frontiers in endurance exercise biology,” Circulation, 129, No. 7, 798–810 (2014), https://doi.org/10.1161/CIRCULATIONAHA.113.001590.
Article PubMed PubMed Central Google Scholar
M. W. Voss, C. Vivar, A. F. Kramer, and H. van Praag, “Bridging animal and human models of exercise-induced brain plasticity,” Trends Cogn. Sci., 17, No. 10, 525–544 (2013), https://doi.org/10.1016/j.tics.2013.08.001.
Article PubMed PubMed Central Google Scholar
Y. M. Heo, M. S. Shin, J. M. Lee, et al., “Treadmill exercise ameliorates short-term memory disturbance in scopolamine-induced amnesia rats,” Int. Neurourol. J., 18, No. 1, 16–22 (2014), https://doi.org/10.5213/inj.2014.18.1.16.
Article PubMed PubMed Central Google Scholar
J. M. Lee, M. S. Shin, E. S. Ji, et al., “Treadmill exercise improves motor coordination through ameliorating Purkinje cell loss in amyloid beta23-35-induced Alzheimer’s disease rats,” J. Exerc. Rehabil., 10, No. 5, 258–264 (2014), https://doi.org/10.12965/jer.140163.
Article PubMed PubMed Central Google Scholar
J. M. Lee, T. W. Kim, S. S. Park, et al., “Treadmill exercise improves motor function by suppressing Purkinje cell loss in Parkinson disease rats,” Int. Neurourol. J., 22, Suppl. 3, S147–S1155 (2018), https://doi.org/10.5213/inj.1836226.113.
Article PubMed PubMed Central Google Scholar
C. E. Garber, B. Blissmer, M. R. Deschenes, et al., “Quantity and quality of exercise for developing and maintaining cardiorespiratory, musculoskeletal, and neuromotor fitness in apparently healthy adults: guidance for prescribing exercise,”. Med. Sci. Sports Exerc. 43, No. 7, 1334–1359 (2011), https://doi.org/10.1249/MSS.0b013e318213fefb.
G. Fisher, A. W. Brown, M. M. Bohan Brown, et al. “High intensity interval- vs. moderate intensity-training for improving cardiometabolic health in overweight or obese males: a randomized controlled trial”. PLoS One., 10, e0138853 (2015).
R. Daabis, M. Hassan, and M. Zidan, “Endurance and strength training in pulmonary rehabilitation for COPD patients,” Egpt. J. Chest Dis. Tuberc., 66, 231–236 (2017), https://doi.org/10.1016/j.ejcdt.2016.07.003.
K. S. Weston, U. Wisløff, and J. S. Coombes, “High-intensity interval training in patients with lifestyle-induced cardiometabolic disease: a systematic review and meta-analysis,” Br. J. Sports Med., 48, No. 16, 1227–1234 (2014), https://doi.org/10.1136/bjsports-2013-092576.
M. J. Gibala, J. P. Little, M. van Essen, et al., “Short-term sprint interval versus traditional endurance training: similar initial adaptations in human skeletal muscle and exercise performance,” J. Physiol., 575, Pt. 3, 901–911 (2006), https://doi.org/10.1113/jphysiol.2006.112094.
CAS Article PubMed PubMed Central Google Scholar
A. Jiménez-Maldonado, I. Rentería, P. C. García-Suárez, et al., “The impact of high-intensity interval training on brain derived neurotrophic factor in brain: a minireview,” Front. Neurosci., 12, 839 (2018), https://doi.org/10.3389/fnins.2018.00839.
Article PubMed PubMed Central Google Scholar
C. L. C. Campêlo, J. R. Santos, A. F. Silva, et al., “Exposure to an enriched environment facilitates motor recovery and prevents short-term memory impairment and reduction of striatal BDNF in a progressive pharmacological model of parkinsonism in mice,” Behav. Brain Res., 328, 138–148 (2017), https://doi.org/10.1016/j.bbr.2017.04.028.
CAS Article PubMed Google Scholar
R. T. de Oliveira, L. A. Felippe, L. T. Bucken, et al., “Benefits of exercise on the executive functions in people with Parkinson disease: a controlled clinical trial,” Am. J. Phys. Med. Rehabil., 96, No. 5, 3010–306 (2017), https://doi.org/10.1097/PHM.0000000000000612.
Y. K. Jeon and C. H. Ha, “The effect of exercise intensity on brain derived neurotrophic factor and memory in adolescents,” Environ. Health Prev. Med., 22, No. 1, 27 (2017), https://doi.org/10.1186/s12199-017-0643-6.
A. Kovacevic, B. Fenesi, F. Paolucci, and J. J. Heisz, “The effects of aerobic exercise intensity on memory in older adults,” Appl. Physiol. Nutr. Metab., 45, No. 6, 591–600 (2020), https://doi.org/10.1139/apnm-2019-0495.
D. Moreau, I. J. Kirk, and K. E. Waldie, “High-intensity training enhances executive function in children in a randomized, placebo-controlled trial,” Elife, 6, e25062 (2017), doi: https://doi.org/10.7554/eLife.25062.
H. Pallesen, M. Bjerk, A. R. Pedersen, et al., “The effects of high-intensity aerobic exercise on cognitive performance after stroke: a pilot randomised controlled trial,” J. Cent. Nerv. Syst. Dis., 11, 1179573519843493 (2019), https://doi.org/10.1177/1179573519843493.
Article PubMed PubMed Central Google Scholar
S. Mekari, H. F. Neyedli, S. Fraser, et al., “High-intensity interval training improves cognitive flexibility in older adults,” Brain Sci., 10, No, 11, 796 (2020), https://doi.org/10.3390/brainsci10110796.
M. Pertusa, S. García-Matas, H. Mammeri H, et al., “Expression of GDNF transgene in astrocytes improves cognitive deficits in aged rats,” Neurobiol. Aging., 29, No. 9, 1366–1379 (2008), https://doi.org/10.1016/j.neurobiolaging.2007.02.026.
O. V. Forlenza, A. S. Miranda, I. Guimar, et al., “Decreased neurotrophic support is associated with cognitive decline in non-demented subjects,” J. Alzheimers Dis., 46, No. 2, 423–429 (2015), https://doi.org/10.3233/JAD-150172.
CAS Article PubMed Google Scholar
R. Gerlai, A. McNamara, D. L. Choi-Lundberg, et al., “Impaired water maze learning performance without altered dopaminergic function in mice heterozygous for the GDNF mutation,” Eur. J. Neurosci., 14, No. 7, 1153–1163 (2001), https://doi.org/10.1046/j.0953-816x.2001.01724.x.
CAS Article PubMed Google Scholar
S. F. Martinez-Huenchullan, B. R. Maharjan, P. F. Williams, et al., “Differential metabolic effects of constant moderate versus high intensity interval training in high-fat fed mice: possible role of muscle adiponectin,” Physiol. Rep., 6, No. 4, e13599 (2018), https://doi.org/10.14814/phy2.13599.
A. Sabaghi, A. Heirani, H. Mahmoodi, and S. Sabaghi,”” High-intensity interval training prevents cognitive-motor impairment and serum BDNF level reduction in Parkinson mice model,” Sport Sci. Health, 15, No. 13, 681–687 (2019), https://doi.org/10.1007/s11332-019-00586-6.
A. Sabaghi, A. Heirani, N. Yousofvand, et al., “Comparison of high-intensity interval training and moderate-intensity continuous training in their effects on behavioral functions and CORT levels in streptozotocin-induced diabetic mice,” Sport Sci. Health, 17, No. 9785, 119–126 (2021), https://doi.org/10.1007/s11332-020-00661-3.
WHO, “Aging and Health,” Available online: https://www.who.int/news-room/fact-sheets/detail/ageing-and-health (accessed on 1 November 2019)
UN, “Ageing,” Available online: https://www.un.org/en/sections/issues-depth/ageing/ (accessed on 18 May 2020).
C. Benedict, S. J. Brooks, J. Kullberg, et al., “Association between physical activity and brain health in older adults,” Neurobiol. Aging, 34, No. 1, 83–90 (2013), https://doi.org/10.1016/j.neurobiolaging.2012.04.013.
L. Donath, S. Ludyga, D. Hammes, et al., “Absolute and relative reliability of acute effects of aerobic exercise on executive function in seniors,” BMC Geriatr., 17, No. 1, 247 (2017).
F. Gheysen, L. Poppe, A. DeSmet, et al., “Physical activity to improve cognition in older adults: can physical activity programs enriched with cognitive challenges enhance the effects? A systematic review and meta-analysis,” Int. J. Behav. Nutr. Phys. Act., 15, No. 1, 63 (2018), https://doi.org/10.1186/s12966-018-0697-x.
E. Santana-Sosa, M. I. Barriopedro, L. M. López-Mojares, et al., “Exercise training is beneficial for Alzheimer’s patients,” Int. J. Sports Med., 29, No. 10, 845–850 (2008), https://doi.org/10.1055/s-2008-1038432.
CAS Article PubMed Google Scholar
E. B. Larson, L. Wang, J. D. Bowen, et al., “Exercise is associated with reduced risk for incident dementia among persons 65 years of age and older,” Ann. Intern. Med., 144. No. 2, 73–81 (2006), https://doi.org/10.7326/0003-4819-144-2-200601170-00004.
N. T. Lautenschlager, K. L. Cox, L. Flicker, et al., “Effect of physical activity on cognitive function in older adults at risk for Alzheimer disease: a randomized trial,” JAMA, 300, No.9, 1027–1037 (2008), https://doi.org/10.1001/jama.300.9.1027.
Z. Radak, N. Hart, L. Sarga, et al., “Exercise plays a preventive role against Alzheimer’s disease,” J. Alzheimers Dis., 20, No. 3, 777–783 (2010), https://doi.org/10.3233/JAD-2010-091531.
K. I. Erickson, A. G. Gildengers, and M. A. Butters, “Physical activity and brain plasticity in late adulthood,” Dialogues Clin. Neurosci., 15. No.1, 99–108 (2013), https://doi.org/10.31887/DCNS.2013.15.1/kerickson.
L. Chaddock-Heyman, K. I. Erickson, J. L. Holtrop, et al., “Aerobic fitness is associated with greater white matter integrity in children,” Front. Hum. Neurosci., 8, 584 (2014), https://doi.org/10.3389/fnhum.2014.00584.
Article PubMed PubMed Central Google Scholar
L. Mandolesi, F. Gelfo, L. Serra L, et al., “Environmental factors promoting neural plasticity: insights from animal and human studies,” Neural Plast., 2017, 7219461 (2017), https://doi.org/10.1155/2017/7219461.
K. I. Erickson, R. S. Prakash, M. W. Voss, et al., “Aerobic fitness is associated with hippocampal volume in elderly humans,” Hippocampus, 19, No. 10, 1030–1039 (2009), https://doi.org/10.1002/hipo.20547.
Article PubMed PubMed Central Google Scholar
A. L. Groover, J. M. Ryals, B. L. Guilford, et al., “Exercise-mediated improvements in painful neuropathy associated with prediabetes in mice,” Pain, 154, No. 12, 2658–2667 (2013), https://doi.org/10.1016/j.pain.2013.07.052.
M. E. Afzalpour, H. T. Chadorneshin, M. Foadoddini, and H. A. Eivari, “Comparing interval and continuous exercise training regimens on neurotrophic factors in rat brain,” Physiol. Behav., 147, 78–83 (2015), https://doi.org/10.1016/j.physbeh.2015.04.012.
CAS Article PubMed Google Scholar
S. Siamilis, J. Jakus, C. Nyakas C, et al., “The effect of exercise and oxidant-antioxidant intervention on the levels of neurotrophins and free radicals in spinal cord of rats,” Spinal Cord, 47, No. 6, 453–457 (2009), https://doi.org/10.1038/sc.2008.125.
M. Guo, V. Lin, W. Davis, et al., “Preischemic induction of TNF-alpha by physical exercise reduces blood-brain barrier dysfunction in stroke,” J. Cereb. Blood Flow Metab., 28, No. 8, 1422–1430 (2008), https://doi.org/10.1038/jcbfm.2008.29.
CAS Article PubMed Google Scholar
Y. H. Ding, C. N. Young, X. Luan, et al., “Exercise preconditioning ameliorates inflammatory injury in ischemic rats during reperfusion,” Acta. Neuropathol., 109, No. 3, 237–246 (2005), https://doi.org/10.1007/s00401-004-0943-y.
CAS Article PubMed Google Scholar
S. Li, Y. Wang, Z. Wang, et al., “Enhanced renoprotective effect of GDNF-modified adipose-derived mesenchymal stem cells on renal interstitial fibrosis,” Stem Cell. Res. Ther., 12, No. 1, 27 (2021), https://doi.org/10.1186/s13287-020-02049-z.
S. Sun, F. Li, X. Gao X, et al., “Calbindin-D28K inhibits apoptosis in dopaminergic neurons by activation of the PI3-kinase-Akt signaling pathway,” Neuroscience, 119, 359–367 (2011),
S. Sun, Q. Zhang, M. Li, et al., “GDNF promotes survival and therapeutic efficacy of human adipose-derived mesenchymal stem cells in a mouse model of Parkinson’s disease,” Cell. Transplant., 29, 963689720908512 (2020), https://doi.org/10.1177/0963689720908512.
M. Duarte Azevedo, S. Sander, and L. Tenenbaum, “GDNF, a neuron-derived factor upregulated in glial cells during disease,” J. Clin. Med., 9, No. 2, 456 (2020), https://doi.org/10.3390/jcm9020456.
K. Yamagata, M. Tagami, K. Ikeda, et al., “Differential regulation of glial cell line-derived neurotrophic factor (GDNF) mRNA expression during hypoxia and reoxygenation in astrocytes isolated from stroke-prone spontaneously hypertensive rats,” Glia, 37, No. 1, 1–7 (2002), https://doi.org/10.1002/glia.10003.
A. Saavedra, G. Baltazar, and E. P. Duarte, “Driving GDNF expression: the green and the red traffic lights,” Prog. Neurobiol., 86, No. 3, 186–215 (2008), https://doi.org/10.1016/j.pneurobio.2008.09.006.
CAS Article PubMed Google Scholar
J. J. Heisz, M. G. Tejada, E. M. Paolucci, and C. Muir, “Enjoyment for high-intensity interval exercise increases during the first six weeks of training: implications for promoting exercise adherence in sedentary adults,” PLoS One, 11, No. 12, e0168534 (2016), https://doi.org/10.1371/journal.pone.0168534.
C. M. Saucedo Marquez, B. Vanaudenaerde, T. Troosters, and N. Wenderoth, “High-intensity interval training evokes larger serum BDNF levels compared with intense continuous exercise,” J. Appl. Physiol. (1985), 119, No. 12, 1363–1373 (2015), https://doi.org/10.1152/japplphysiol.00126.2015.
J. J. Chapman, J. S. Coombes, W
Comments (0)