J. Jankovic, A. H. Rajput, M. P. McDermott, and D. P. Perl, “The evolution of diagnosis in early Parkinson disease,” Arch. Neurol., 57, No. 3, 369–372 (2000).

M. Canesi, R. Benti, G. Marotta, et al., “Striatal dopamine transporter binding in patients with Parkinson’s disease and severe occupational hydrocarbon exposure,” Eur. J. Neurol., 14, No. 3, 297–299 (2007).

CAS  PubMed  Google Scholar 

S. Fahn and D. Sulzer, “Neurodegeneration and neuroprotection in Parkinson Disease,” NeuroRx, 1, No. 1, 139–154 (2004).

Article  Google Scholar 

I. T. Niculescu (ed.), Pathomorphology of the Nervous System [In Russian], Medical Publishing House, Bucharest, 987p. (1963).

M.-F. Chesselet and F. Richter, “Modelling of Parkinson’s disease in mice,” Lancet Neurol., 10, No. 12, 1108–1118 (2011); doi: https://doi.org/10.1016/S1474-4422(11)70227-7.

Article  PubMed  Google Scholar 

A. H. Schapira, “Etiology and pathogenesis of Parkin- son disease,” Neurol. Clin., 27, No. 3, 583–603 (2009).

Article  Google Scholar 

D. J. Brooks, “Neuroimaging in Parkinson’s disease,” NeuroRx, 1, No. 2, 243–254 (2004).

Article  Google Scholar 

B. A. Faucheux, M.-E. Martin, C. Beaumont, et al., “Neuromelanin associated redox-active iron is increased in the substantia nigra of patients with Parkinson’s disease,” J. Neurochem., 86, No. 5, 1 142–1148 (2003).

G. Ebersbach, C. Moreau, F. Gandor et al., “Clinical syndromes: Parkinsonian gait,” Mov. Disord., 28, No. 11, 1552–1559 (2013).

Article  Google Scholar 

J. P. Bolam and E. K. Pissadaki, “Living on the edge with too many mouths to feed: why dopamine neurons die,” Mov. Disord., 27, No. 12, 1478–1483 (2012).

CAS  Article  Google Scholar 

T. A. Yacoubian and D. G. Standaert, “Targets for neuroprotection in Parkinson’s disease,” Biochim. Biophys. Acta, 1792, No. 7, 676–687 (2009).

CAS  Article  Google Scholar 

C. C. Stichel, X.-R. Zhu, V. Bader, et al., “Mono- and double-mutant mouse models of Parkinson’s disease display severe mitochondrial damage,” Hum. Mol. Genet., 16, No. 20, 2377–2393 (2007).

CAS  Article  Google Scholar 

S. Schmidt, B. Linnartz, S. Mendritzki, et al., “Genetic mouse models for Parkinson’s disease display severe pathology in glial cell mitochondria,” Hum. Mol. Genet., 20, No. 6, 1 197–1211 (2011).

A. A. Galoyan, V. S. Aprikian, K. A. Markossian, and B. Ya. Gurvitz, “Neurosecretion of cytokines by magnocellular cells of hypothalamus,” Neurochemistry (RAS & NAS RA), 15, No. 4, 361-372 (1998).

CAS  Google Scholar 

A. A. Galoyan, J. S. Sarkissian, T. K. Kipriyan, et al., “Protective effect of the new hypothalamic peptides against cobra venom and trauma-induced neuronal injury,” Neurochem. Res., 26, No. 8–9, 1023–1038 (2001).

CAS  Article  Google Scholar 

K. Yenkoyan, K. Fereshetyan, S. Matinyan, et al., “The role of monoamines in the development of Alzheimer’s disease and neuroprotective effect of a proline rich polypeptide,” Prog. Neuropsychopharmacol. Biol. Psychiatry, 86, 76–82 (2018).

CAS  Article  Google Scholar 

V. S. Aprikian and A. А. Galoyan, “Immunoprotective properties of a novel hypothalamic polypeptide in bacterial pathologies [In Russian],” Med. Sci. Armenia, 39, No. 2, 23–29 (1999).

Google Scholar 

A. Akopian and A. Galoyan, “Effect of hypothalamic proline-rich-polypeptide on voltage-gated Ca2+ currents in retinal ganglion cells,” Neurochem. Res., 28, No. 12, 1867–1871 (2004).

Article  Google Scholar 

R. M. Srapionyan, Z. Ch. Paronyan, F. M. Sahakyan, and A. A. Galoyan, “Study of the role of proline rich peptide in the regulation of the hemostasis system [In Russian],” Neirokhimia, 31, No. 1, 54–57 (2014).

Google Scholar 

G. Faure, “Natural inhibitors of toxic phospholipases A2,” Biochimie, 82, No. 9–10, 833–840 (2000).

CAS  Article  Google Scholar 

S. K. Costa, L. C. Esquisatto, E. Camargo, et al., “Comparative effect of Phoneutria nigriventer spider venom and capsaicin on the rat paw oedema,” Life Sci., 69, No. 13, 1573–1585 (2001).

CAS  Article  Google Scholar 

N. S. Cook (ed.), Potassium Channels: Structure, Classification, Function and Therapeutic Potential, Ellis Horwood Ltd., Chichester, 1990.

Google Scholar 

L. Harvey, “Defining and measuring employability,” Quality Higher Educ., 7, No. 2, 97–109 (2001).

Article  Google Scholar 

C. G. Moreira, J. K. Barbiero, D. Ariza, et al., “Behavioral, neurochemical and histological alterations promoted by bilateral intranigral rotenone administration: A new approach for an old neurotoxin,” Neurotox. Res., 21, No. 3, 291–301 (2012).

CAS  Article  Google Scholar 

G. Paxinos and C. Watson, The Rat Brain in Stereotaxic Coordinates (5th ed.), Academic Press, New York (2005), 367p.

I. B. Meliksetyan, “The revealing of Ca2+-dependent activity of acid phosphatase in cell structures of rat brain [In Russian],” Morfologia, 131, No. 2, 77–80 (2007).

CAS  Google Scholar 

I. Ch. Sharova, Invertebrate Zoology [In Russian], Humanist Publishing Center VLADOS, Moscow, 592 pp. (2002).

Google Scholar 

W. J. Streit, J. R. Conde, S. E. Fendrick, et al., “Role of microglia in the central nervous system’s immune response,” Neurol Res., 27, No. 7, 685–691 (2005).

Article  Google Scholar 

M. E. Kalaitzakis, M. B. Graeber, S. M. Gentleman, and R. K. B. Pearce, “Controversies over the staging of alpha-synuclein pathology in Parkinson’s disease,” Acta Neuropathol., 116, No. 1, 125–128 (2008).

Article  Google Scholar 

F. L. Episcopo, C. Tirolo, N. Testa, et al., “Reactive astrocytes are key players in nigrostriatal dopaminergic neurorepair in the MPTP mouse model of Parkinson’s disease: focus on endogenous neurorestoration,” Curr. Aging Sci., 6, No. 1, 45–55 (2013).

CAS  Article  Google Scholar 

P. M. Rappold and K. Tieu, “Astrocytes and therapeutics for Parkinson’s disease,” Neurotherapeutics, 7, No. 4, 413–423 (2010).

CAS  Article  Google Scholar 

C. M. Tanner, F. Kamel, G. W. Ross, et al. “Rotenone, paraquat, and Parkinson’s disease,” Environ. Health Perspect., 119, No. 6, 866–872 (201 1).

A. V. Osipov, Study of Cobras Underrepresented in Venom Proteins of New Structural Types [In Russian], Author’s thesis for the degree of Candidate of Chemical Sciences, Moscow (2014).

A. A. Galoyan, Biochemistry of Novel Cardioactive Hormones and Immunomodulators of the Functional System Neurosecretory Hypothalamus – Endocrine Heart, Nauka Publishers, Moscow (1997), 242p.

Google Scholar