1.
WHO Expert Committee on Drug Dependence . World Health Organization technical report series 942. 2006:i.
https://pubmed.ncbi.nlm.nih.gov/17373571/ Google Scholar2.
Feyissa, AM, Kelly, JP. A review of the neuropharmacological properties of khat. Prog Neuropsychopharmacol Biol Psychiatry. 2008;32:1147-1166.
Google Scholar |
Crossref |
Medline3.
Toennes, SW, Harder, S, Schramm, M, Niess, C, Kauert, GF. Pharmacokinetics of cathinone, cathine and norephedrine after the chewing of khat leaves. Br J Clin Pharmacol. 2003;56:125-130.
Google Scholar |
Crossref |
Medline |
ISI4.
Al-Motarreb, A, Baker, K, Broadley, KJ. Khat: pharmacological and medical aspects and its social use in Yemen. Phytother Res. 2002;16:403-413.
Google Scholar |
Crossref |
Medline5.
Shojima, N, Sakoda, H, Ogihara, T, et al. Humoral regulation of resistin expression in 3T3-L1 and mouse adipose cells. Diabetes. 2002;51:1737-1744.
Google Scholar |
Crossref |
Medline6.
El-Sayed, MIK, Amin, HA-K. Effect of Catha edulis on insulin, resistin and cortisol levels in type-2 diabetics and non-diabetics. Am J Biochem Biotechnol. 2012;8:157-163.
Google Scholar |
Crossref7.
Barth, E, Albuszies, G, Baumgart, K, et al. Glucose metabolism and catecholamines. Crit Care Med. 2007;35:S508-S518.
Google Scholar |
Crossref |
Medline |
ISI8.
Al-Hashem, FH, Bin-Jaliah, I, Dallak, MA, et al. Khat (Catha edulis) extract increases oxidative stress parameters and impairs renal and hepatic functions in rats. Bahrain Med Bull. 2011;33:32-36.
Google Scholar9.
Yan, L-J . Pathogenesis of chronic hyperglycemia: from reductive stress to oxidative stress. J Diabetes Res. 2014;2014;10;3-5.
Google Scholar10.
Hassan, N, Gunaid, A, Murray Lyon, I. Khat [Catha edulis]: health aspects of khat chewing. East Mediterr Health J. 2007;13:706-718.
Google Scholar |
Medline11.
Badedi, M, Darraj, H, Hummadi, A, et al. Khat chewing and Type 2 diabetes mellitus. Diabetes Metab Syndr Obes. 2020;13:307-312.
Google Scholar |
Crossref |
Medline12.
Halket, J, Karasu, Z, Murray-Lyon, I. Plasma cathinone levels following chewing khat leaves (Catha edulis Forsk.). J Ethnopharmacol. 1995;49:111-113.
Google Scholar |
Crossref |
Medline |
ISI13.
Saif-Ali, R, Al-Qirbi, A, Al-Geiry, A, Al-Habori, M. Effect of Catha edulis on plasma glucose and C-peptide in both type 2 diabetics and non-diabetics. J Ethnopharmacol. 2003;86:45-49.
Google Scholar |
Crossref |
Medline |
ISI14.
Mahmood, SA, Lindequist, U. A pilot study on the effect of Catha edulis Frosk., (Celastraceae) on metabolic syndrome in WOKW rats. Afr J Tradit Complement Altern Med. 2008;5:271-277.
Google Scholar |
Crossref |
Medline15.
Atef, Z, Bamashmos, M, Alghazali, G. Effect of Qat on the level of blood glucose and lipids among Yemeni patients with type 2 diabetes. Egypt J Obes Diab Endocrinol. 2017;3:100-105.
Google Scholar16.
VanVoorhis, CW, Morgan, BL. Understanding power and rules of thumb for determining sample sizes. Tutor Quant Methods Psychol. 2007;3:43-50.
Google Scholar |
Crossref17.
Burson, R, Moran, KJ. Reviewing the 2017 American Diabetes Association standards of medical care. Home Healthc Now. 2017;35:339-340.
Google Scholar |
Crossref |
Medline18.
Eliud, NM, Peter, GK. Trace elements content of selected Kenyan antidiabetic medicinal plants. Int J Curr Pharm Res. 2012;4:39-42.
Google Scholar19.
Ting, HH, Timimi, FK, Boles, KS, Creager, SJ, Ganz, P, Creager, MA. Vitamin C improves endothelium-dependent vasodilation in patients with non-insulin-dependent diabetes mellitus. J Clin Invest. 1996;97:22-28.
Google Scholar |
Crossref |
Medline |
ISI20.
Afkhami-Ardekani, M, Shojaoddiny-Ardekani, A. Effect of vitamin C on blood glucose, serum lipids & serum insulin in type 2 diabetes patients. Indian J Med Res. 2007;126:471-474.
Google Scholar |
Medline |
ISI21.
Tadele, A, Getachew, T, Defar, A, et al. Effect of Khat consumption on blood biochemical parameters: evidences from the Ethiopian non communicable diseases STEPS survey, 2015. Ethiop J Public Health Nutr. 2021;4:129-135.
Google Scholar22.
Taleb, M, Bechyne, M. Effect of Catha edulis leaves on plasma glucose. Agric Trop Subtrop. 2009;42:46-48.
Google Scholar23.
Al-Ashwal, RH, Al-maqtari, M, Naji, KM, Alwsabai, NA, Al Hazmy, SM. Potential health effects of daily khat leaves chewing: study on the biochemical blood constituents changes among adults in Sana’a city Yemen. Inter J Biochemist Biotechnol. 2013;2:461-463.
Google Scholar24.
Alsalahi, A, Alshawsh, MA, Mohamed, R, Alyousefi, NA, Alshagga, MA, Shwter, AN, Al-Maqtari, A, Ahmed, RH, Mohamed, Z. Conflicting reports on the role of the glycemic effect of Catha edulis (Khat): A systematic review and meta-analysis. J Ethnopharmacol. 2016;186:30-43.
Google Scholar |
Crossref |
Medline25.
Wabe, NT . Chemistry, pharmacology, and toxicology of khat (catha edulis forsk): a review. Addict Health. 2011;3(3-4):137-149.
Google Scholar |
Medline26.
Alkhormi, AH, Alshahrani, NZ, Mahmood, SE. Khat chewing leads to increase in glycaemic parameters in patients with type 2 diabetes mellitus in Jazan region, Saudi Arabia and Yemen. Diabetes Metab Syndr: Clin Res Rev. 2021 Mar 3.
Google Scholar |
Crossref |
Medline27.
Al-Motarreb, A, Al-Habori, M, Broadley, KJ. Khat chewing, cardiovascular diseases and other internal medical problems: the current situation and directions for future research. J Ethnopharmacol. 2010;132:540-548.
Google Scholar |
Crossref |
Medline |
ISI28.
Mann, E, Sunni, M, Bellin, MD. Secretion of insulin in response to diet and hormones. Pancreapedia. Published online December 23, 2020. doi:
10.3998/panc.2020.16 Google Scholar |
Crossref29.
Toschi, E, Camastra, S, Sironi, AM, et al. Effect of acute hyperglycemia on insulin secretion in humans. Diabetes. 2002;51(suppl 1):S130-S133.
Google Scholar |
Crossref |
Medline |
ISI30.
El-Sayed, MI, Amin, HA. Effect of Catha edulis on insulin, resistin and cortisol levels in type-2 diabetics and non-diabetics. Am J Biochem Biotechnol. 2012;8:157-163.
Google Scholar |
Crossref31.
Yigazu, DM, Desse, TA. Glycemic control and associated factors among type 2 diabetic patients at Shanan Gibe Hospital, Southwest Ethiopia. BMC Res Notes. 2017;10:1-6.
Google Scholar |
Crossref |
Medline32.
Eid, M, Mafauzy, M, Faridah, A. Glycaemic control of type 2 diabetic patients on follow up at Hospital Universiti Sains Malaysia. Malays J Med Sci. 2003;10:40.
Google Scholar |
Medline33.
Tekalegn, Y, Addissie, A, Kebede, T, Ayele, W. Magnitude of glycemic control and its associated factors among patients with type 2 diabetes at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia. PLoS One. 2018;13:e0193442.
Google Scholar |
Crossref |
Medline34.
Achila, OO, Ghebretinsae, M, Kidane, A, Simon, M, Makonen, S, Rezene, Y. Factors associated with poor glycemic and lipid levels in ambulatory diabetes mellitus type 2 patients in Asmara, Eritrea: a cross-sectional study. J Diabetes Res. 2020;2020:1-12.
Google Scholar |
Crossref35.
Mamo, Y, Bekele, F, Nigussie, T, Zewudie, A. Determinants of poor glycemic control among adult patients with type 2 diabetes mellitus in Jimma University Medical Center, Jimma zone, south west Ethiopia: a case control study. BMC Endocr Disord. 2019;19:1-11.
Google Scholar |
Crossref |
Medline36.
Wysham, C, Shubrook, J. Beta-cell failure in type 2 diabetes: mechanisms, markers, and clinical implications. Postgrad Med. 2020;132:676-686.
Google Scholar |
Crossref |
Medline37.
Kassahun, T, Eshetie, T, Gesesew, H. Factors associated with glycemic control among adult patients with type 2 diabetes mellitus: a cross-sectional survey in Ethiopia. BMC Res Notes. 2016;9:1-6.
Google Scholar |
Crossref |
Medline38.
Mweng’emeke, M, Bintabara, D, Ernest, A, Mpondo, BC. Predictors of glycaemic control among adults attending a diabetic outpatient clinic in a Tertiary hospital, Tanzania: a cross sectional study. Tanzan Med J. 2016;28:109-127.
Google Scholar39.
Almutairi, MA, Said, SM, Zainuddin, H. Predictors of poor glycemic control among type two diabetic patients. Am J Med Med Sci. 2013;3:17-21.
Google Scholar40.
Alzaheb, RA, Altemani, AH. The prevalence and determinants of poor glycemic control among adults with type 2 diabetes mellitus in Saudi Arabia. Diabetes Metab Syndr Obes. 2018;11:15-21.
Google Scholar |
Crossref |
Medline41.
David, E, Aderemi-Williams, R, Soremekun, R, Nasiru, I, Auta, A. Glycemic control and its determinants among patients with type 2 diabetes in a specialist hospital in northeast, Nigeria. SAJ Pharmacol. 2019;105:6-8.
Google Scholar42.
Kayar, Y, Ilhan, A, Kayar, NB, et al. Relationship between the poor glycemic control and risk factors, life style and complications. Biomed Res. 2017;28.
Google Scholar43.
Silva Dias, J, Ortiz, R. Advanced Breeding Tools in Vegetable Crops. In: Silva Dias, J (ed.) Prime Archives in Agricultural Research. Vide Leaf. 2019.
Google Scholar44.
da Silva Dias, JC, Imai, S. Vegetables consumption and its benefits on diabetes. J Nutr Ther. 2017;6:1-10.
Google Scholar |
Crossref
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