N.A. Tritos, K.K. Miller, Diagnosis and management of pituitary adenomas: a review. J. Am. Med. Assoc. 329, 1386–1398 (2023). https://doi.org/10.1001/jama.2023.5444

Article  CAS  Google Scholar 

Y. Shozo, O. Kenichi, T. Manabu, T. Akira, M. Koji, T. Koji et al., A study of the correlation between morphological findings and biological activities in clinically nonfunctioning pituitary adenomas. Neurosurgery. 61, 584–585 (2007). https://doi.org/10.1227/01.Neu.0000290906.53685.79

Article  Google Scholar 

S.L. Asa, O. Mete, A. Perry, R.Y. Osamura, Overview of the 2022 WHO classification of pituitary tumors. Endocr. Pathol. 33, 6–26 (2022). https://doi.org/10.1007/s12022-022-09703-7

Article  PubMed  CAS  Google Scholar 

S.S. Jayant, R. Pal, A. Rai, K. Gupta, B.D. Radotra, R. Walia et al., Paediatric pituitary adenomas: clinical presentation, biochemical profile and long-term prognosis. Neurol. India. 70, 304–311 (2022). https://doi.org/10.4103/0028-3886.338667

Article  PubMed  Google Scholar 

O. Mete, M.B. Lopes, Overview of the 2017 WHO classification of pituitary tumors. Endocr. Pathol. 28, 228–243 (2017). https://doi.org/10.1007/s12022-017-9498-z

Article  PubMed  CAS  Google Scholar 

G. Ntali, C. Capatina, A. Grossman, N. Karavitaki, Functioning gonadotroph adenomas. J. Clin. Endocrinol. Metab. 99, 4423–4433 (2014). https://doi.org/10.1210/jc.2014-2362

Article  PubMed  CAS  Google Scholar 

G.A.-O. Ntali, C. Capatina, Updating the landscape for functioning gonadotroph tumors. Medicina. 58, 1071 (2022)

Article  PubMed  PubMed Central  Google Scholar 

A. Etzrodt, H. Etzrodt, O. Hey, FSH-producing hypophyseal tumor in a 13-year-old Girl. Geburtshilfe Frauenheilkd. 50, 73–75 (1990). https://doi.org/10.1055/s-2007-1026437

Article  PubMed  CAS  Google Scholar 

H. Tashiro, H. Katabuchi, H. Ohtake, T. Kaku, Y. Ushio, H. Okamura, A follicle-stimulating hormone–secreting gonadotroph adenoma with ovarian enlargement in a 10-year-old Girl. Fertil. Steril. 72, 158–160 (1999). https://doi.org/10.1016/S0015-0282(99)00197-1

Article  PubMed  CAS  Google Scholar 

H. Tashiro, H. Katabuchi, H. Ohtake, A. Yoshioka, S. Matsumura, Y. Suenaga et al., An immunohistochemical and ultrastructural study of a follicle-stimulating hormone-secreting gonadotroph adenoma occurring in a 10-year-old Girl. Med. Electron. Microsc. 33, 25–31 (2000). https://doi.org/10.1007/s007950000004

Article  PubMed  CAS  Google Scholar 

M. Clemente, F. Caracseghi, M. Gussinyer, D. Yeste, M. Albisu, E. Vázquez et al., Macroorchidism and panhypopituitarism: two different forms of presentation of FSH-secreting pituitary adenomas in adolescence. Horm. Res. Paediatr. 75, 225–230 (2011). https://doi.org/10.1159/000322211

Article  PubMed  CAS  Google Scholar 

M.G. Gryngarten, D. Braslavsky, M.G. Ballerini, J. Ledesma, M.G. Ropelato, M.E. Escobar, Spontaneous ovarian hyperstimulation syndrome caused by a follicle-stimulating hormone-secreting pituitary Macroadenoma in an early pubertal Girl. Horm. Res. Paediatr. 73, 293–298 (2010). https://doi.org/10.1159/000284395

Article  PubMed  CAS  Google Scholar 

G. Vargas, L. Balcazar-Hernandez, V. Melgar, R. Magriña-Mercado, B. Gonzalez, J. Baquera et al., An FSH and TSH pituitary adenoma, presenting with precocious puberty and central hyperthyroidism. Endocrinol Diabetes Metab Case Rep. 2017, (2017). https://doi.org/10.1530/edm-17-0057

M. Ceraudo, D. Criminelli Rossi, N. Di Iorgi, A. Cama, G. Piatelli, A. Consales, Pediatric pituitary adenoma with mixed FSH and TSH immunostaining and FSH hypersecretion in a 6 year-old Girl with precocious puberty: case report and multidisciplinary management. Int. J. Neurosci. 132, 362–369 (2022). https://doi.org/10.1080/00207454.2020.1815734

Article  PubMed  CAS  Google Scholar 

C.P.A.C. Group, Consensus of surgical treatment experts for pituitary adenomas in China. Natl. Med. J. China. 95, 324–329 (2015)

Google Scholar 

J. Garcia, G. Jones, A. Acosta, G. Wright, Human menopausal gonadotropin/human chorionic gonadotropin follicular maturation for oocyte aspiration: phase II, 1981. Fertil. Steril. 39, 174–179 (1983). https://doi.org/10.1016/s0015-0282(16)46815-9

Article  PubMed  CAS  Google Scholar 

B. Fauser, A. Van Heusden, Manipulation of human ovarian function: physiological concepts and clinical consequences. Endocr. Rev. 18, 71–106 (1997). https://doi.org/10.1210/edrv.18.1.0290

Article  PubMed  CAS  Google Scholar 

L. Wang, H. Liang, C. Deng, Q. Yu, F. Gong, F. Feng et al., Functioning gonadotroph adenomas in premenopausal women: clinical and molecular characterization and review of the literature. Pituitary. 25, 454–467 (2022). https://doi.org/10.1007/s11102-021-01205-9

Article  PubMed  CAS  Google Scholar 

W. A J, H. K K, and L. L. Contrasting effects of oral and transdermal routes of Estrogen replacement therapy on 24-hour growth hormone (GH) secretion, insulin-like growth factor I, and GH-binding protein in postmenopausal women. J. Clin. Endocrinol. Metab. 72, (1991). https://doi.org/10.1210/jcem-72-2-374

U.J. Meinhardt, K.K.Y. Ho, Modulation of growth hormone action by sex steroids. Clin. Endocrinol. (Oxf). 65, 413–422 (2006). https://doi.org/https://doi.https://doi.org/10.1111/j.1365-2265.2006.02676.x

Article  PubMed  CAS  Google Scholar 

R. Coutant, F.B. de Casson, S. Rouleau, O. Douay, E. Mathieu, F. Gatelais et al., Divergent effect of endogenous and exogenous sex steroids on the insulin-like growth factor I response to growth hormone in short normal adolescents. J. Clin. Endocrinol. Metab. 89, 6185–6192 (2004). https://doi.org/10.1210/jc.2004-0814

Article  PubMed  CAS  Google Scholar 

D. Heseltine, M.C. White, P. Kendall-Taylor, D.M. De Kretser, W. Kelly, Testicular enlargement and elevated serum inhibin concentrations occur in patients with pituitary macroadenomas secreting follicle stimulating hormone. Clin. Endocrinol. (Oxf). 31, 411–423 (1989). https://doi.org/10.1111/j.1365-2265.1989.tb01265.x

Article  PubMed  CAS  Google Scholar 

P. Pigny, B. Henric, N. Lahlou, S. Christin, M. Mazzuca, D. Dewailly et al., A gonadotroph adenoma with a high proportion of basic FSH isohormones by chromatofocusing. J. Clin. Endocrinol. Metab. 81, 2407–2408 (1996). https://doi.org/10.1210/jcem.81.6.8964889

Article  PubMed  CAS  Google Scholar 

S. Borgato, L. Persani, R. Romoli, D. Cortelazzi, A. Spada, P. Beck-Peccoz, Serum FSH bioactivity and inhibin levels in patients with gonadotropin secreting and nonfunctioning pituitary adenomas. J. Endocrinol. Invest. 21, 372–379 (1998). https://doi.org/10.1007/bf03350773

Article  PubMed  CAS  Google Scholar 

M. Papandreou, C. Asteria, K. Pettersson, C. Ronin, P. Beck-Peccoz, Concanavalin A affinity chromatography of human serum gonadotropins: evidence for changes of carbohydrate structure in different clinical conditions. J. Clin. Endocrinol. Metab. 76, 1008–1013 (1993). https://doi.org/10.1210/jcem.76.4.8473374

Article  PubMed  CAS  Google Scholar 

N. Lahlou, E. Le Nestour, P. Chanson, D. Seret-Bégué, P. Bouchard, M. Roger et al., Inhibin and follicle-stimulating hormone levels in gonadotroph adenomas: evidence of a positive correlation with tumour volume in men. Clin. Endocrinol. (Oxf). 38, 301–309 (1993). https://doi.org/10.1111/j.1365-2265.1993.tb01010.x

Article  PubMed  CAS  Google Scholar 

P. Marta, V. Esther, Ovarian hyperstimulation, hyperprolactinaemia and LH gonadotroph adenoma. Reprod. Biomed. Online. 19, 153–155 (2009). https://doi.org/10.1016/s1472-6483(10)60065-x

Article  Google Scholar 

R.E. Peterson, I.A. Kourides, M. Horwith, E.D. Jr. Vaughan, B.B. Saxena, R.A.R. Fraser, Luteinizing hormone- and α-subunit-secreting pituitary tumor: positive feedback of Estrogen. J. Clin. Endocrinol. Metab. 52, 692–698 (1981). https://doi.org/10.1210/jcem-52-4-692

Article  PubMed  CAS  Google Scholar 

S.H. Roman, M. Goldstein, I.A. Kourides, F. Comite, C.W. Bardin, D.T. Krieger, The luteinizing hormone-releasing hormone (LHRH) agonist [D-Trp6-Pro9-NEt]LHRH increased rather than Lowered LH and α-Subunit levels in a patient with an LH- secreting pituitary tumor. J. Clin. Endocrinol. Metab. 58, 313–319 (1984). https://doi.org/10.1210/jcem-58-2-313

Article  PubMed  CAS  Google Scholar 

A. Klibanski, P.J. Deutsch, J.L. Jameson, E.C. Ridgway, W.F. Crowley, D.W. Hsu et al., Luteinizing hormone-secreting pituitary tumor: biosynthetic characterization and clinical studies. J. Clin. Endocrinol. Metab. 64, 536–542 (1987). https://doi.org/10.1210/jcem-64-3-536

Article  PubMed