To assess the patterns of use of ASA-statin free combinations in primary care: a population-based study in Italy

T. Liu, R. Zuo, J. Wang et al. Cardiovascular disease preventive effects of aspirin combined with different statins in the United States general population. Sci. Rep. 13(1), 4585 (2023)

Article  CAS  PubMed  PubMed Central  Google Scholar 

S.G. Sepanlou, J.F.E. Mann, P. Joseph et al. Fixed-dose combination therapy for the prevention of cardiovascular diseases in CKD: an individual participant data meta-analysis. Clin. J. Am. Soc. Nephrol. 18(11), 1408–1415 (2023). https://doi.org/10.2215/CJN.0000000000000251

Article  PubMed  PubMed Central  Google Scholar 

P. Joseph, G. Roshandel, P. Gao et al. Fixed-dose combination therapies with and without aspirin for primary prevention of cardiovascular disease: an individual participant data meta-analysis. Lancet 398(10306), 1133–1146 (2021)

Article  CAS  PubMed  Google Scholar 

N. Ferri, M. Ruscica, R.D. Santos et al. Fixed combination for the treatment of dyslipidaemia. Curr. Atheroscler. Rep. 25(10), 691–699 (2023)

Article  CAS  PubMed  PubMed Central  Google Scholar 

S. Baroletti, H. Dell’Orfano, Medication adherence in cardiovascular disease. Circulation 121(12), 1455–1458 (2010)

Article  PubMed  Google Scholar 

M.J. Butler, A.M.N. Romain, R. Augustin et al. The effect of a multi-component behavior change technique intervention on medication adherence among individuals on primary prevention statin therapy: a dose-finding protocol. Trials 24(1), 523 (2023)

Article  PubMed  PubMed Central  Google Scholar 

M. Levi, A. Pasqua, I. Cricelli et al. Patient adherence to olmesartan/amlodipine combinations: fixed versus extemporaneous combinations. J. Manag. Care Spec. Pharm. 22(3), 255–262 (2016)

PubMed  Google Scholar 

D.L. Vetrano, E. Bianchini, G. Onder et al. Poor adherence to chronic obstructive pulmonary disease medications in primary care: role of age, disease burden and polypharmacy. Geriatr. Gerontol. Int. 17(12), 2500–2506 (2017). https://doi.org/10.1111/ggi.13115

Article  PubMed  Google Scholar 

N. Lombardi, G. Crescioli, M. Simonetti et al. Adherence to triple-free-drug combination therapies among patients with cardiovascular disease. Am. J. Cardiol. 125(9), 1429–1435 (2020)

Article  CAS  PubMed  Google Scholar 

V. Guglielmi, A. Bellia, S. Pecchioli et al. Effectiveness of adherence to lipid lowering therapy on LDL-cholesterol in patients with very high cardiovascular risk: a real-world evidence study in primary care. Atherosclerosis 263, 36–41 (2017)

Article  CAS  PubMed  Google Scholar 

S. Karve, M.A. Cleves, M. Helm et al. Good and poor adherence: optimal cut-point for adherence measures using administrative claims data. Curr. Med. Res. Opin. 25(9), 2303–2310 (2009)

Article  PubMed  Google Scholar 

L. Osterberg, T. Blaschke, Adherence to medication. N. Engl. J. Med. 353(5), 487–497 (2005)

Article  CAS  PubMed  Google Scholar 

J. Cuzick, M.A. Thorat, C. Bosetti et al. Estimates of benefits and harms of prophylactic use of aspirin in the general population. Ann. Oncol. 26(1), 47–57 (2015)

Article  CAS  PubMed  Google Scholar 

S. Burato, L. Leonardi, I.C. Antonazzo et al. Comparing the prevalence of polypharmacy and potential drug-drug interactions in nursing homes and in the community dwelling elderly of emilia romagna region. Front. Pharmacol. 11, 624888 (2020)

Article  PubMed  Google Scholar 

C.C. Szeto, K. Sugano, J.G. Wang et al. Non-steroidal anti-inflammatory drug (NSAID) therapy in patients with hypertension, cardiovascular, renal or gastrointestinal comorbidities: Joint APAGE/APLAR/APSDE/APSH/APSN/PoA recommendations. Gut 69(4), 617–629 (2020)

Article  CAS  PubMed  Google Scholar 

K. McDowell, J.N. Clements, How can NSAIDs harm cardiovascular and renal function? JAAPA 27(4), 12–15 (2014)

Article  PubMed  Google Scholar 

R.M. Conroy, K. Pyörälä, A.P. Fitzgerald et al. Estimation of ten-year risk of fatal cardiovascular disease in Europe: The SCORE project. Eur. Heart J. 24(11), 987–1003 (2003)

Article  CAS  PubMed  Google Scholar 

G.R. Dagenais, P. Pais, P. Gao et al. Fixed dose combination therapies in primary cardiovascular disease prevention in different groups: an individual participant meta-analysis. Heart 109(18), 1372–1379 (2023)

Article  CAS  PubMed  Google Scholar 

G.Y.H. Lip, A. Genaidy, B. Jones et al. Medication non-adherence patterns and profiles for patients with incident myocardial infarction: observations from a large multi-morbid US population. Eur. J. Clin. Invest. 53(6), e13968 (2023)

Article  CAS  PubMed  Google Scholar 

V. Belleudi, M. Di Martino, S. Cascini et al. The impact of adherence to inhaled drugs on 5-year survival in COPD patients: a time dependent approach. Pharmacoepidemiol. Drug. Saf. 25(11), 1295–1304 (2016)

Article  CAS  PubMed  PubMed Central  Google Scholar 

I.M. Danelich, S.S. Wright, J.M. Lose et al. Safety of nonsteroidal antiinflammatory drugs in patients with cardiovascular disease. Pharmacotherapy 35(5), 520–535 (2015)

Article  PubMed  Google Scholar 

J. Gensichen, M. von Korff, M. Peitz et al. Case management for depression by health care assistants in small primary care practices: a cluster randomized trial. Ann. Intern. Med. 151(6), 369–378 (2009)

Article  PubMed  Google Scholar 

W.J. Katon, M. Von Korff, E.H.B. Lin et al. The Pathways Study: a randomized trial of collaborative care in patients with diabetes and depression. Arch. Gen. Psychiatry 61(10), 1042–1049 (2004)

Article  PubMed  Google Scholar 

W.A. Ray, Evaluating medication effects outside of clinical trials: new-user designs. Am. J. Epidemiol. 158(9), 915–920 (2003)

Article  PubMed  Google Scholar 

A. Biffi, L. Scotti, F. Rea et al. Adherence to antidepressants and mortality in elderly patients with cardiovascular disease. Clin. Drug. Investig. 38(7), 593–602 (2018). https://doi.org/10.1007/s40261-018-0642-4

Article  PubMed  Google Scholar 

M.C.S. Wong, J. Liu, S. Zhou et al. The association between multimorbidity and poor adherence with cardiovascular medications. Int. J. Cardiol. 177(2), 477–482 (2014)

Article  PubMed  Google Scholar 

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