Iannello A, Thompson TW, Ardolino M, Marcus A, Raulet DH. Immunosurveillance and immunotherapy of tumors by innate immune cells. Curr Opin Immunol. 2016;38:52–8.

CAS  PubMed  Google Scholar 

Herberman RB, Nunn ME, Lavrin DH. Natural cytotoxic reactivity of mouse lymphoid cells against syngeneic and allogeneic tumors. I. Distribution of reactivity and specificity. Int J Cancer. 1975;16(2):216–29.

CAS  PubMed  Google Scholar 

Anfossi N, André P, Guia S, Falk CS, Roetynck S, Stewart CA, et al. Human NK cell education by inhibitory receptors for MHC class I. Immunity. 2006;25:331–42.

CAS  PubMed  Google Scholar 

Boudreau JE, Mulrooney TJ, Le Luduec J-B, Barker E, Hsu KC. KIR3DL1 and HLA-B density and binding calibrate NK education and response to HIV. J Immunol. 2016;196:3398–410.

CAS  PubMed  Google Scholar 

Bottino C, Castriconi R, Moretta L, Moretta A. Cellular ligands of activating NK receptors. Trends Immunol. 2005;26:221–6.

CAS  PubMed  Google Scholar 

Horowitz A, Strauss-Albee DM, Leipold M, Kubo J, Nemat-Gorgani N, Dogan OC, et al. Genetic and environmental determinants of human NK cell diversity revealed by mass cytometry. Sci Transl Med. 2013;5:208ra145.

PubMed  PubMed Central  Google Scholar 

Uhrberg M. Shaping the human NK cell repertoire: an epigenetic glance at KIR gene regulation. Mol Immunol. 2005;42:471–5.

CAS  PubMed  Google Scholar 

Yawata M, Yawata N, Draghi M, Partheniou F, Little A-M, Parham P. MHC class I-specific inhibitory receptors and their ligands structure diverse human NK-cell repertoires toward a balance of missing self-response. Blood. 2008;112:2369–80.

CAS  PubMed  PubMed Central  Google Scholar 

Ferron E, David G, Willem C, Legrand N, Salameh P, Anquetil L, et al. Multifactorial determinants of NK cell repertoire organization: insights into age, sex, KIR genotype, HLA typing, and CMV influence. Front Immunol. 2024;15:1389358.

CAS  PubMed  PubMed Central  Google Scholar 

Makanga DR, Da Rin de Lorenzo F, David G, Willem C, Dubreuil L, Legrand N, et al. Genetic and molecular basis of heterogeneous NK cell responses against acute leukemia. Cancers (Basel). 2020;12:E1927.

Björkström NK, Riese P, Heuts F, Andersson S, Fauriat C, Ivarsson MA, et al. Expression patterns of NKG2A, KIR, and CD57 define a process of CD56dim NK-cell differentiation uncoupled from NK-cell education. Blood. 2010;116:3853–64.

PubMed  Google Scholar 

Béziat V, Descours B, Parizot C, Debré P, Vieillard V. NK cell terminal differentiation: correlated stepwise decrease of NKG2A and acquisition of KIRs. PLoS ONE. 2010;5:e11966.

PubMed  PubMed Central  Google Scholar 

Lopez-Vergès S, Milush JM, Pandey S, York VA, Arakawa-Hoyt J, Pircher H, et al. CD57 defines a functionally distinct population of mature NK cells in the human CD56dimCD16+ NK-cell subset. Blood. 2010;116:3865–74.

PubMed  PubMed Central  Google Scholar 

Djaoud Z, David G, Bressollette C, Willem C, Rettman P, Gagne K, et al. Amplified NKG2C+ NK cells in cytomegalovirus (CMV) infection preferentially express killer cell Ig-like receptor 2DL: Functional impact in controlling CMV-infected dendritic cells. J Immunol. 2013;191:2708–16.

CAS  PubMed  Google Scholar 

Gumá M, Budt M, Sáez A, Brckalo T, Hengel H, Angulo A, et al. Expansion of CD94/NKG2C+ NK cells in response to human cytomegalovirus-infected fibroblasts. Blood. 2006;107:3624–31.

PubMed  Google Scholar 

Rebuffet L, Melsen JE, Escalière B, Basurto-Lozada D, Bhandoola A, Björkström NK, et al. High-dimensional single-cell analysis of human natural killer cell heterogeneity. Nat Immunol. 2024;25(8):1474–88.

CAS  PubMed  PubMed Central  Google Scholar 

Crinier A, Milpied P, Escalière B, Piperoglou C, Galluso J, Balsamo A, et al. High-dimensional single-cell analysis identifies organ-specific signatures and conserved NK cell subsets in humans and mice. Immunity. 2018;49:971-986.e5.

CAS  PubMed  PubMed Central  Google Scholar 

Morvan M, David G, Sébille V, Perrin A, Gagne K, Willem C, et al. Autologous and allogeneic HLA KIR ligand environments and activating KIR control KIR NK-cell functions. Eur J Immunol. 2008;38:3474–86.

CAS  PubMed  Google Scholar 

Willem C, Makanga DR, Guillaume T, Maniangou B, Legrand N, Gagne K, et al. Impact of KIR/HLA incompatibilities on NK cell reconstitution and clinical outcome after T cell-replete haploidentical hematopoietic stem cell transplantation with posttransplant cyclophosphamide. J Immunol. 2019;202:2141–52.

CAS  PubMed  Google Scholar 

Sun JY, Gaidulis L, Miller MM, Goto RM, Rodriguez R, Forman SJ, et al. Development of a multiplex PCR-SSP method for Killer-cell immunoglobulin-like receptor genotyping. Tissue Antigens. 2004;64:462–8.

CAS  PubMed  Google Scholar 

Borowitz MJ, Lynn Guenther K, Shults KE, Stelzer GT. Immunophenotyping of acute leukemia by flow cytometric analysis: Use of CD45 and right-angle light scatter to gate on leukemic blasts in three-color analysis. Am J Clin Pathol. 1993;100:534–40.

CAS  PubMed  Google Scholar 

Chaumette T, Cinotti R, Mollé A, Solomon P, Castain L, Fourgeux C, et al. Monocyte signature associated with herpes simplex virus reactivation and neurological recovery after brain injury. Am J Respir Crit Care Med. 2022;206:295–310.

CAS  PubMed  Google Scholar 

Charpentier E, Cornec M, Dumont S, Meistermann D, Bordron P, David L, et al. 3’ RNA sequencing for robust and low-cost gene expression profiling. 2021. https://doi.org/10.21203/rs.3.pex-1336/v1

Letellier T, Kervella D, Sadek A, Masset C, Garandeau C, Fourgeux C, et al. Time-limited therapy with belatacept in kidney transplant recipients. J Clin Med. 2022;11:3229.

CAS  PubMed  PubMed Central  Google Scholar 

Dubreuil L, Maniangou B, Chevallier P, Quéméner A, Legrand N, Béné MC, et al. Centromeric KIR AA individuals harbor particular KIR alleles conferring beneficial NK cell features with implications in haplo-identical hematopoietic stem cell transplantation. Cancers. 2020;12:3595.

CAS  PubMed  PubMed Central  Google Scholar 

Gagne K, Willem C, Legrand N, Djaoud Z, David G, Rettman P, et al. Both the nature of KIR3DL1 alleles and the KIR3DL1/S1 allele combination affect the KIR3DL1 NK-cell repertoire in the French population. Eur J Immunol. 2013;43:1085–98.

CAS  PubMed  Google Scholar 

Ren X, Peng M, Xing P, Wei Y, Galbo PM, Corrigan D, et al. Blockade of the immunosuppressive KIR2DL5/PVR pathway elicits potent human NK cell-mediated antitumor immunity. J Clin Invest. 2022;132:e163620.

CAS  PubMed  PubMed Central  Google Scholar 

Ruggeri L, Capanni M, Urbani E, Perruccio K, Shlomchik WD, Tosti A, et al. Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplants. Science. 2002;295:2097–100.

CAS  PubMed  Google Scholar 

Meazza R, Ruggeri L, Guolo F, Minetto P, Canevali P, Loiacono F, et al. Donor selection for adoptive immunotherapy with NK cells in AML patients: Comparison between analysis of lytic NK cell clones and phenotypical identification of alloreactive NK cell repertoire. Front Immunol. 2023;14:1111419.

CAS  PubMed  PubMed Central  Google Scholar 

Brenchley JM, Karandikar NJ, Betts MR, Ambrozak DR, Hill BJ, Crotty LE, et al. Expression of CD57 defines replicative senescence and antigen-induced apoptotic death of CD8+ T cells. Blood. 2003;101:2711–20.

CAS  PubMed  Google Scholar 

Covre LP, Fantecelle CH, Queiroz AM, Fardin JM, Miranda PH, Henson S, et al. NKG2C+CD57+ natural killer cells with senescent features are induced during cutaneous leishmaniasis and accumulate in patients with lesional healing impairment. Clin Exp Immunol. 2024;217:279–90.

PubMed  PubMed Central  Google Scholar 

Merino A, Zhang B, Dougherty P, Luo X, Wang J, Blazar BR, et al. Chronic stimulation drives human NK cell dysfunction and epigenetic reprograming. J Clin Invest. 2019;129:3770–85.

PubMed  PubMed Central  Google Scholar 

Gao F, Mora MC, Constantinides M, Coënon L, Multrier C, Vaillant L, et al. Feeder cell training shapes the phenotype and function of in vitro expanded natural killer cells. MedComm. 2020;2024(5):e740.

Google Scholar 

Witalisz-Siepracka A, Denk C-M, Zdársky B, Hofmann L, Edtmayer S, Harm T, et al. STAT3 in acute myeloid leukemia facilitates natural killer cell-mediated surveillance. Front Immunol. 2024;15:1374068.

CAS  PubMed  PubMed Central  Google Scholar 

Xiao Y, Chen J, Wang J, Guan W, Wang M, Zhang L, et al. Acute myeloid leukemia epigenetic immune escape from nature killer cells by ICAM-1. Front Oncol. 2021;11:751834.

CAS  PubMed  PubMed Central  Google Scholar 

Archimbaud E, Thomas X, Campos L, Magaud JP, Doré JF, Fiere D. Expression of surface adhesion molecules CD54 (ICAM-1) and CD58 (LFA-3) in adult acute leukemia: relationship with initial characteristics and prognosis. Leukemia. 1992;6:265–71.

CAS  PubMed  Google Scholar 

Thulasi Raman R, Anurekha M, Lakshman V, Balasubramaniam R, Ramya U, Revathi R. Immunophenotypic modulation in pediatric B lymphoblastic leukemia and its implications in MRD detection. Leuk Lymphoma. 2020;61:1974–80.