Pulmonary outcomes of pediatric patients with postinfectious bronchiolitis obliterans treated with pulse methylprednisolone and intravenous immunoglobulin: a single-center cohort study

Fischer GB et al (2010) Post infectious bronchiolitis obliterans in children. Paediatr Respir Rev 11(4):233–239

PubMed  Google Scholar 

Zhang L et al (2000) Clinical course of postinfectious bronchiolitis obliterans. Pediatr Pulmonol 29(5):341–350

CAS  PubMed  Google Scholar 

Mazenq J et al (2024) Post viral bronchiolitis obliterans in children: a rare and potentially devastating disease. Paediatr Respir Rev 52:58–65

PubMed  Google Scholar 

Tomikawa SO et al (2014) Follow-up on pediatric patients with bronchiolitis obliterans treated with corticosteroid pulse therapy. Orphanet J Rare Dis 9:128

PubMed  PubMed Central  Google Scholar 

Jerkic SP et al (2020) Postinfectious bronchiolitis obliterans in children: diagnostic workup and therapeutic options: a workshop report. Can Respir J 2020:5852827

PubMed  PubMed Central  Google Scholar 

Rosewich M et al (2015) Airway inflammation in children and adolescents with bronchiolitis obliterans. Cytokine 73(1):156–162

CAS  PubMed  Google Scholar 

Flanagan F et al (2022) Post-infectious bronchiolitis obliterans in children. Paediatr Respir Rev 42:69–78

PubMed  Google Scholar 

de Benedictis FM, Canny GJ, Levison H (1996) The role of corticosteroids in respiratory diseases of children. Pediatr Pulmonol 22(1):44–57

PubMed  Google Scholar 

Bleecker ER et al (2020) Systematic literature review of systemic corticosteroid use for asthma management. Am J Respir Crit Care Med 201(3):276–293

PubMed  PubMed Central  Google Scholar 

Yilmaz AI et al (2023) Successful treatment of postinfectious bronchiolitis obliterans with gamma globulin in a tertiary center: 10 years of experience. Pediatr Pulmonol 58(10):2769–2776

PubMed  Google Scholar 

Clement A (2004) Task force on chronic interstitial lung disease in immunocompetent children. Eur Respir J 24(4):686–697

CAS  PubMed  Google Scholar 

Desmarquest P et al (1998) Chronic interstitial lung disease in children: response to high-dose intravenous methylprednisolone pulses. Pediatr Pulmonol 26(5):332–338

CAS  PubMed  Google Scholar 

Griese M (2018) Chronic interstitial lung disease in children. Eur Respir Rev 27(147):27(147)

Google Scholar 

Stanojevic S et al (2022) ERS/ATS technical standard on interpretive strategies for routine lung function tests. Eur Respir J 60(1):2101499

PubMed  Google Scholar 

Onay ZR et al (2020) Postinfectious bronchiolitis obliterans masked by misdiagnosis as asthma. Pediatr Pulmonol 55(4):1007–1011

PubMed  Google Scholar 

Jerkic SP et al (2021) Long-term course of bronchial inflammation and pulmonary function testing in children with postinfectious bronchiolitis obliterans. Pediatr Pulmonol 56(9):2966–2972

PubMed  Google Scholar 

Cazzato S et al (2008) Airway inflammation and lung function decline in childhood post-infectious bronchiolitis obliterans. Pediatr Pulmonol 43(4):381–390

PubMed  Google Scholar 

Colom AJ et al (2015) Pulmonary function of a paediatric cohort of patients with postinfectious bronchiolitis obliterans. A long term follow-up. Thorax 70(2):169–174

PubMed  Google Scholar 

Colom AJ et al (2006) Risk factors for the development of bronchiolitis obliterans in children with bronchiolitis. Thorax 61(6):503–506

CAS  PubMed  PubMed Central  Google Scholar 

Yao MM et al (2024) Risk factors for bronchiolitis obliterans complicating adenovirus pneumonia in children: a meta-analysis. Front Pediatr 12:1361850

PubMed  PubMed Central  Google Scholar 

Fischer GB, Teper A, Colom AJ (2002) Acute viral bronchiolitis and its sequelae in developing countries. Paediatr Respir Rev 3(4):298–302

PubMed  Google Scholar 

Potti P et al (2024) Postinfectious bronchiolitis obliterans: knowledge, attitude, and practice survey. J Pediatr Pulmonol 3(3):62–68

Google Scholar 

Yu J (2015) Postinfectious bronchiolitis obliterans in children: lessons from bronchiolitis obliterans after lung transplantation and hematopoietic stem cell transplantation. Korean J Pediatr 58(12):459–465

CAS  PubMed  PubMed Central  Google Scholar 

Moonnumakal SP, Fan LL (2008) Bronchiolitis obliterans in children. Curr Opin Pediatr 20(3):272–278

PubMed  Google Scholar 

Kavaliunaite E, Aurora P (2019) Diagnosing and managing bronchiolitis obliterans in children. Expert Rev Respir Med 13(5):481–488

CAS  PubMed  Google Scholar 

Kim CK et al (2001) Bronchiolitis obliterans in the 1990s in Korea and the United States. Chest 120(4):1101–1106

CAS  PubMed  Google Scholar 

Yoon HM et al (2015) Post-infectious bronchiolitis obliterans in children: CT features that predict responsiveness to pulse methylprednisolone. Br J Radiol 88(1049):20140478

CAS  PubMed  PubMed Central  Google Scholar 

Tomikawa SO et al (2024) Methylprednisolone intravenous pulse therapy for pediatric patients with post-infectious bronchiolitis obliterans: an update. J Bras Pneumol 50(2):e20230373

PubMed  PubMed Central  Google Scholar 

Hislop AA (2002) Airway and blood vessel interaction during lung development. J Anat 201(4):325–334

PubMed  PubMed Central  Google Scholar 

Jones MH, Pitrez PM, Stein RT (2004) Post-infectious bronchiolitis obliterans. Pediatr Pulmonol Suppl 26:64–65

PubMed  Google Scholar 

Sahraei Z et al (2023) The efficacy of high-dose pulse therapy vs. low-dose intravenous methylprednisolone on severe to critical COVID-19 clinical outcomes: a randomized clinical trial. Iran J Pharm Res 22(1):e137838

PubMed  PubMed Central  Google Scholar 

Salvarani C et al (2022) Intravenous methylprednisolone pulses in hospitalised patients with severe COVID-19 pneumonia: a double-blind, randomised, placebo-controlled trial. Eur Respir J 60(4):2200025

CAS  PubMed  PubMed Central  Google Scholar 

Sabir S, Werth VP (2000) Pulse glucocorticoids. Dermatol Clin 18(3):437–446, viii-ix

Reynaud J et al (2025) Efficacy and tolerance of intravenous methylprednisolone pulses in children with severe bronchopulmonary dysplasia requiring respiratory support. Pediatr Pulmonol 60(1):e27344

PubMed  Google Scholar 

Liu X, Cao W, Li T (2020) High-dose intravenous immunoglobulins in the treatment of severe acute viral pneumonia: the known mechanisms and clinical effects. Front Immunol 11:1660

CAS  PubMed  PubMed Central  Google Scholar 

Gökturk B (2017) Successful therapy with intravenous gamma globulin in two children with postinfectious bronchiolitis obliterans. J Pulmonol Respir Res 1(1):009–012

Google Scholar 

Jirarattanasopa N et al (2010) A combination of intravenous immunoglobulin and pulse methylprednisolone extended survival in pulmonary alveolar proteinosis with chronic interstitial pneumonitis: a case report. Asian Pac J Allergy Immunol 28(2–3):200–205

CAS  PubMed  Google Scholar 

Mhaske DS et al (2022) An observational study of clinical profile & short-term outcome with use of pulse therapy of methylprednisolone alone vs methylprednisolone and intravenous immunoglobulin in multisystem inflammatory syndrome in children. VIMS Health Sci Journal 9(1):08–13

Google Scholar 

Ouldali N et al (2021) Association of intravenous immunoglobulins plus methylprednisolone vs immunoglobulins alone with course of fever in multisystem inflammatory syndrome in children. JAMA 325(9):855–864

CAS  PubMed  Google Scholar 

Sheianov MV et al (2020) Pulse therapy with corticosteroids and intravenous immunoglobulin in the management of severe tocilizumab-resistant COVID-19: a report of three clinical cases. Cureus 12(7):e9038

PubMed  PubMed Central  Google Scholar 

Sullivan KM et al (1996) A controlled trial of long-term administration of intravenous immunoglobulin to prevent late infection and chronic graft-vs.-host disease after marrow transplantation: clinical outcome and effect on subsequent immune recovery. Biol Blood Marrow Transplant 2(1):44–53

CAS  PubMed  Google Scholar 

Tanou K, Xaidara A, Kaditis A (2015) Efficacy of pulse methylprednisolone in a pediatric case of postinfectious bronchiolitis obliterans. Pediatr Pulmonol. https://doi.org/10.1002/ppul.23157

PubMed  Google Scholar 

Ratjen F, Rjabko O, Kremens B (2005) High-dose corticosteroid therapy for bronchiolitis obliterans after bone marrow transplantation in children. Bone Marrow Transplant 36(2):135–138

CAS  PubMed  Google Scholar 

Comments (0)

No login
gif