Comprehensive identification of a migrasomes-associated long non-coding RNA signature to predict the prognosis and treatment options in colon adenocarcinoma

Rajamanickam S, Agarwal R. Natural products and colon cancer: current status and future prospects. Drug Dev Res. 2008;69(7):460–71.

CAS  PubMed  PubMed Central  Google Scholar 

Wu YJ, Cai ZQ, He RM, Wang XC, Cong LL, Qiu FH. Knockdown of long noncoding RNA 01124 inhibits the malignant behaviors of colon cancer cells via miR-654-5p/HAX-1. Evid Based Complement Alternat Med. 2022;2022:1092107.

PubMed  PubMed Central  Google Scholar 

Benson AB, Venook AP, Al-Hawary MM, Arain MA, Chen YJ, Ciombor KK, Cohen S, Cooper HS, Deming D, Farkas L, et al. Colon cancer, Version 2.2021, NCCN clinical practice guidelines in oncology. J Natl Compr Canc Netw. 2021;19(3):329–59.

PubMed  Google Scholar 

Ma L, Li Y, Peng J, Wu D, Zhao X, Cui Y, Chen L, Yan X, Du Y, Yu L. Discovery of the migrasome, an organelle mediating release of cytoplasmic contents during cell migration. Cell Res. 2015;25(1):24–38.

CAS  PubMed  Google Scholar 

Zhao X, Lei Y, Zheng J, Peng J, Li Y, Yu L, Chen Y. Identification of markers for migrasome detection. Cell Discov. 2019;5:27.

CAS  PubMed  PubMed Central  Google Scholar 

Wu D, Xu Y, Ding T, Zu Y, Yang C, Yu L. Pairing of integrins with ECM proteins determines migrasome formation. Cell Res. 2017;27(11):1397–400.

CAS  PubMed  PubMed Central  Google Scholar 

Jiang D, Jiang Z, Lu D, Wang X, Liang H, Zhang J, Meng Y, Li Y, Wu D, Huang Y, et al. Migrasomes provide regional cues for organ morphogenesis during zebrafish gastrulation. Nat Cell Biol. 2019;21(8):966–77.

CAS  PubMed  Google Scholar 

Zhang R, Peng J, Zhang Y, Zheng K, Chen Y, Liu L, Li T, Liu J, Li Y, Yang S, et al. Pancreatic cancer cell-derived migrasomes promote cancer progression by fostering an immunosuppressive tumor microenvironment. Cancer Lett. 2024;605: 217289.

CAS  PubMed  Google Scholar 

Sun L, Yu J, Wang P, Shen M, Ruan S. HIT000218960 promotes gastric cancer cell proliferation and migration through upregulation of HMGA2 expression. Oncol Lett. 2019;17(6):4957–63.

CAS  PubMed  PubMed Central  Google Scholar 

Yang S, Chen J, Yu Y, Li D, Huang M, Yuan L, Yin G. Long noncoding RNA ROR as a novel biomarker for progress and prognosis outcome in human cancer: a meta-analysis in the Asian population. Cancer Manag Res. 2018;10:4641–52.

CAS  PubMed  PubMed Central  Google Scholar 

Cai J, Ji Z, Wu J, Chen L, Zheng D, Chen Y, Zhang X, Xie W, Huang J, Chen M, et al. Development and validation of a novel endoplasmic reticulum stress-related lncRNA prognostic signature and candidate drugs in breast cancer. Front Genet. 2022;13: 949314.

CAS  PubMed  PubMed Central  Google Scholar 

Wang K, Yu J, Xu Q, Peng Y, Li H, Lu Y, Ouyang M. Disulfidptosis-related long non-coding RNA signature predicts the prognosis, tumor microenvironment, immunotherapy, and antitumor drug options in colon adenocarcinoma. Apoptosis. 2024;71:209.

Google Scholar 

Qin Y, Yang J, Liang C, Liu J, Deng Z, Yan B, Fu Y, Luo Y, Li X, Wei X, et al. Pan-cancer analysis identifies migrasome-related genes as a potential immunotherapeutic target: a bulk omics research and single cell sequencing validation. Front Immunol. 2022;13: 994828.

CAS  PubMed  PubMed Central  Google Scholar 

Zheng Y, Lang Y, Qi B, Li T. TSPAN4 and migrasomes in atherosclerosis regression correlated to myocardial infarction and pan-cancer progression. Cell Adh Migr. 2023;17(1):14–9.

CAS  PubMed  Google Scholar 

Sagaert X, Vanstapel A, Verbeek S. Tumor heterogeneity in colorectal cancer: what do we know so far? Pathobiology. 2018;85(1–2):72–84.

CAS  PubMed  Google Scholar 

da Rocha-Azevedo B, Schmid SL. Migrasomes: a new organelle of migrating cells. Cell Res. 2015;25(1):1–2.

PubMed  Google Scholar 

Chen L, Ma L, Yu L. WGA is a probe for migrasomes. Cell Discov. 2019;5:13.

CAS  PubMed  PubMed Central  Google Scholar 

Saito S, Tanaka M, Tatematsu S, Okochi M. Peptide-modified substrate enhances cell migration and migrasome formation. Mater Sci Eng C Mater Biol Appl. 2021;131: 112495.

CAS  PubMed  Google Scholar 

Yang C, Hu JF, Zhan Q, Wang ZW, Li G, Pan JJ, Huang L, Liao CY, Huang Y, Tian YF, et al. SHCBP1 interacting with EOGT enhances O-GlcNAcylation of NOTCH1 and promotes the development of pancreatic cancer. Genomics. 2021;113(2):827–42.

CAS  PubMed  Google Scholar 

Yu S, Yu L. Migrasome biogenesis and functions. FEBS J. 2022;289(22):7246–54.

CAS  PubMed  Google Scholar 

Jiao H, Jiang D, Hu X, Du W, Ji L, Yang Y, Li X, Sho T, Wang X, Li Y, et al. Mitocytosis, a migrasome-mediated mitochondrial quality-control process. Cell. 2021;184(11):2896–910.

CAS  PubMed  Google Scholar 

Cao J, Wu L, Lei X, Shi K, Shi L, Shi Y. Long non-coding RNA-based signature for predicting prognosis of hepatocellular carcinoma. Bioengineered. 2021;12(1):673–81.

CAS  PubMed  PubMed Central  Google Scholar 

Bhan A, Soleimani M, Mandal SS. Long noncoding RNA and cancer: a new paradigm. Cancer Res. 2017;77(15):3965–81.

CAS  PubMed  PubMed Central  Google Scholar 

Tan YT, Lin JF, Li T, Li JJ, Xu RH, Ju HQ. LncRNA-mediated posttranslational modifications and reprogramming of energy metabolism in cancer. Cancer Commun (Lond). 2021;41(2):109–20.

PubMed  Google Scholar 

Peng WX, Koirala P, Mo YY. LncRNA-mediated regulation of cell signaling in cancer. Oncogene. 2017;36(41):5661–7.

CAS  PubMed  PubMed Central  Google Scholar 

Wang W, Liu Y, Wang Z, Tan X, Jian X, Zhang Z. Exploring and validating the necroptotic gene regulation and related lncRNA mechanisms in colon adenocarcinoma based on multi-dimensional data. Sci Rep. 2024;14(1):22251.

CAS  PubMed  PubMed Central  Google Scholar 

Kim Z, Lee J, Yoon YE, Yun JW. Unveiling prognostic RNA biomarkers through a multi-cohort study in colorectal cancer. Int J Mol Sci. 2024;25(6):3317.

CAS  PubMed  PubMed Central  Google Scholar 

Chen X, Ye Z, Lou P, Liu W, Liu Y. Comprehensive analysis of metabolism-related lncRNAs related to the progression and prognosis in osteosarcoma from TCGA. J Orthop Surg Res. 2021;16(1):523.

PubMed  PubMed Central  Google Scholar 

Hu D, Messadi DV. Immune-related long non-coding RNA signatures for tongue squamous cell carcinoma. Curr Oncol. 2023;30(5):4817–32.

PubMed  PubMed Central  Google Scholar 

Xu Q, Liu T, Wang J. Radiosensitization-related cuproptosis LncRNA signature in non-small cell lung cancer. Genes (Basel). 2022;13(11):2080.

CAS  PubMed  Google Scholar 

Liu J, Ye L, Li Q, Wu X, Wang B, Ouyang Y, Yuan Z, Li J, Lin C. Synaptopodin-2 suppresses metastasis of triple-negative breast cancer via inhibition of YAP/TAZ activity. J Pathol. 2018;244(1):71–83.

CAS  PubMed  Google Scholar 

Gan W, Dai X, Dai X, Xie J, Yin S, Zhu J, Wang C, Liu Y, Guo J, Wang M, et al. LATS suppresses mTORC1 activity to directly coordinate Hippo and mTORC1 pathways in growth control. Nat Cell Biol. 2020;22(2):246–56.

CAS  PubMed  PubMed Central  Google Scholar 

Zhang J, Wang G, Chu SJ, Zhu JS, Zhang R, Lu WW, Xia LQ, Lu YM, Da W, Sun Q. Loss of large tumor suppressor 1 promotes growth and metastasis of gastric cancer cells through upregulation of the YAP signaling. Oncotarget. 2016;7(13):16180–93.

PubMed  PubMed Central  Google Scholar 

Zhou D, Zhang Y, Wu H, Barry E, Yin Y, Lawrence E, Dawson D, Willis JE, Markowitz SD, Camargo FD, et al. Mst1 and Mst2 protein kinases restrain intestinal stem cell proliferation and colonic tumorigenesis by inhibition of Yes-associated protein (Yap) overabundance. Proc Natl Acad Sci U S A. 2011;108(49):E1312-1320.

CAS  PubMed  PubMed Central  Google Scholar 

Shen Z, Pan Y, Chen P, Jiang B, Fang X, Jiang Y. LATS1 exerts tumor suppressor functions via targeting Gli1 in colorectal cancer. J Cancer. 2021;12(24):7311–9.

CAS  PubMed  PubMed Central  Google Scholar 

Comments (0)

No login
gif