Vitamin D supplementation improves genu varum in toddlers: two-center pilot study

Engel GM, Staheli LT (1974) The natural history of torsion and other factors influencing gait in childhood. A study of the angle of gait, tibial torsion, knee angle, hip rotation, and development of the arch in normal children. Clin Orthop Relat Res 99:12–17

Article  Google Scholar 

Yoo JH, Choi IH, Cho TJ, Chung CY, Yoo WJ (2008) Development of tibiofemoral angle in Korean children. J Korean Med Sci 23:714–717

Article  PubMed  PubMed Central  Google Scholar 

Weiner DS (1981) The natural history of “bow legs” and “knock knees” in childhood. Orthopedics 4:156–160

Article  CAS  PubMed  Google Scholar 

Sakamoto Y, Ishijima M, Nakano S, Suzuki M, Liu L, Tokita A, Kim SG, Shimizu T, Kaneko K, Nozawa M (2020) Physiologic leg bowing is not a physiologic condition but instead is associated with vitamin D disorders in toddlers. Calcif Tissue Int 106:95–103

Article  CAS  PubMed  Google Scholar 

Nakajima H, Sakamoto Y, Honda Y, Sasaki T, Igeta Y, Ogishima D, Matsuoka S, Kim SG, Ishijima M, Miyagawa K (2023) Estimation of the vitamin D (VD) status of pregnant Japanese women based on food intake and VD synthesis by solar UV-B radiation using a questionnaire and UV-B observations. J Steroid Biochem Mol Biol 229:106272

Article  CAS  PubMed  Google Scholar 

Levine AM, Drennan JC, Contcut N (1982) Physiological bowing and tibia vara. J Bone Jt Surg Am 64:1158–1163

Article  CAS  Google Scholar 

Salenius P, Vankka E (1975) The development of the tibiofemoral angle in children. J Bone Jt Surg Am 57:259–261

Article  CAS  Google Scholar 

Foreman KA, Robertson WW Jr (1985) Radiographic measurement of infantile tibia vara. J Pediatr Orthop 5:452–455

Article  CAS  PubMed  Google Scholar 

O’Neill DA, MacEwen GD (1982) Early roentgenographic evaluation of bowlegged children. J Pediatr Orthop 2:547–553

Article  PubMed  Google Scholar 

Gaudinez R, Adar U (1996) Use of Orthofix T-Garche fixator in late-onset tibia vara. J Pediatr Orthop 16:455–460

Article  CAS  PubMed  Google Scholar 

Stricker SJ, Faustgen JP (1994) Radiographic measurement of bowleg deformity: variability due to method and limb rotation. J Pediatr Orthop 14:147–151

Article  CAS  PubMed  Google Scholar 

Akhmedov B, Ahn S, Chung CY, Lee KM, Sung KH, Kim TW, Lee SY, Choi IH, Cho TJ, Yoo WJ, Park MS (2013) Estimation of the recovery of physiological genu varum with linear mixed model. J Pediatr Orthop 33:439–445

Article  PubMed  Google Scholar 

Bowen RE, Dorey FJ, Moseley CF (2002) Relative tibial and femoral varus as a predictor of progression of varus deformities of the lower limbs in young children. J Pediatr Orthop 22:105–111

Article  PubMed  Google Scholar 

Jamil K, Chew WY, Bohari NE, George S, Isahak NH, Boopalachandran B, Hamizan AW, Ibrahim S (2022) Knee measurements among children with normal alignment, physiologic and pathologic bowing aged 0–3 years old: a systematic review. J Pediatr Orthop B 31:105–113

Article  PubMed  Google Scholar 

Shinohara Y, Kamegaya M, Kuniyoshi K, Moriya H (2002) Natural history of infantile tibia vara. J Bone Jt Surg Br 84:263–268

Article  CAS  Google Scholar 

Bathfield CA, Beighton PH (1978) Blount disease. A review of etiological factors in 110 patients. Clin Orthop Relat Res 135:29–33

Google Scholar 

Munns CF, Shaw NJ, Kiely M, Specker BL, Thacher TD et al (2016) Global consensus recommendations on prevention and management of nutritional rickets. J Clin Endocrinol Metab 101:394–415

Article  CAS  PubMed  PubMed Central  Google Scholar 

Akazawa Y, Shiohara M, Amano Y, Uchida N, Nakamura S, Minami I, Yasui K, Kurata K, Koike K (2010) The clinical characteristics of vitamin D deficiency in childhood: a systematic literature review of Japanese patients. J Pediatr Endocrinol Metab 23:675–684

Article  CAS  PubMed  Google Scholar 

Matsuo K, Mukai T, Suzuki S, Fujieda K (2009) Prevalence and risk factors of vitamin D deficiency rickets in Hokkaido, Japan. Pediatr Int 51:559–562

Article  CAS  PubMed  Google Scholar 

Yorifuji J, Yorifuji T, Tachibana K, Nagai S, Kawai M, Momoi T, Nagasaka H, Hatayama H, Nakahata T (2008) Craniotabes in normal newborns: the earliest sign of subclinical vitamin D deficiency. J Clin Endocrinol Metab 93:1784–1788

Article  CAS  PubMed  Google Scholar 

Nakamura K, Ueno K, Nishiwaki T, Okuda Y, Saito T, Tsuchiya Y, Yamamoto M (2005) Nutrition, mild hyperparathyroidism, and bone mineral density in young Japanese women. Am J Clin Nutr 82:1127–1133

Article  CAS  PubMed  Google Scholar 

Shimbo S, Imai Y, Tominaga N, Gotoh T, Yokota M, Inoguchi N, Ikeda Y, Watanabe T, Moon C, Ikeda M (1996) Insufficient calcium and iron intakes among general female population in Japan, with special reference to inter-regional differences. J Trace Elem Med Biol 10:133–138

Article  CAS  PubMed  Google Scholar 

Nakamura K, Saito T, Yoshihara A, Ishikawa M, Tsuchiya Y, Oshiki R, Kobayashi R, Maruyama K, Hyodo K, Nashimoto M, Tsugawa N, Okano T, Oyama M, Yamamoto M (2009) Low calcium intake is associated with increased bone resorption in postmenopausal Japanese women: Yokogoshi study. Public Health Nutr 12:2366–2370

Article  PubMed  Google Scholar 

Yoneyama R, Shimizu H, Beppu M (2008) Correlation of bone status in mothers and daughters and the improvement of bone status. J Orthop Sci 13:405–412

Article  PubMed  Google Scholar 

Miyamoto H, Kawakami D, Hanafusa N, Nakanishi T, Miyasaka M, Furutani Y, Ikeda Y, Ito K, Kato T, Yokoyama K, Arakawa S, Saito M, Furusho T, Matsuura T, Ochi S (2023) Determination of a serum 25-hydroxyvitamin D reference ranges in Japanese adults using fully automated liquid chromatography-tandem mass spectrometry. J Nutr 153:1253–1264

Article  PubMed  Google Scholar 

Kuwabara A, Tsugawa N, Mizuno K, Ogasawara H, Watanabe Y, Tanaka K (2019) A simple questionnaire for the prediction of vitamin D deficiency in Japanese adults (vitamin D deficiency questionnaire for Japanese: VDDQ-J). J Bone Miner Metab 37:854–863

Article  CAS  PubMed  Google Scholar 

Nakano S, Suzuki M, Minowa K, Hirai S, Takubo N, Sakamoto Y, Ishijima M, Hoshino E, Tokita A, Shimizu T (2018) Current vitamin D status in healthy Japanese infants and young children. J Nutr Sci Vitaminol 64:99–105

Article  CAS  PubMed  Google Scholar 

Comments (0)

No login
gif