From starvation to time-restricted eating: a review of fasting physiology

Asher G, Sassone-Corsi P. Time for food: the intimate interplay between nutrition, metabolism, and the circadian clock. Cell. 2015;161:84–92.

Article  CAS  PubMed  Google Scholar 

Chaix A, Manoogian ENC, Melkani GC, Panda S. Time-restricted eating to prevent and manage chronic metabolic diseases. Annu Rev Nutr. 2019;39:291–315.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Longo VD, Panda S. Fasting, circadian rhythms, and time-restricted feeding in healthy lifespan. Cell Metab. 2016;23:1048–59.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Owen OE, Morgan AP, Kemp HG, Sullivan JM, Herrera MG, Cahill GF Jr. Brain metabolism during fasting. J Clin Invest. 1967;46:1589–95.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Owen OE, Reichard GA Jr. Ketone body metabolism in normal, obese and diabetic subjects. Isr J Med Sci. 1975;11:560–70.

CAS  PubMed  Google Scholar 

Owen OE. Mini-series: paths to discovery. Ketone bodies as a fuel of the brain during starvation. Biochem Mol Biol Educ. 2005;33:246–51.

Article  CAS  Google Scholar 

Moro T, Tinsley G, Bianco A, Marcolin G, Pacelli QF, Battaglia G, et al. Effects of eight weeks of time-restricted feeding (16/8) on basal metabolism, maximal strength, body composition, inflammation, and cardiovascular risk factors in resistance-trained males. J Transl Med. 2016;14:290.

Article  PubMed  PubMed Central  Google Scholar 

Templeman I, Gonzalez JT, Thompson D, Betts JA. The role of intermittent fasting and meal timing in weight management and metabolic health. Proc Nutr Soc. 2020;79:76–87.

Article  PubMed  Google Scholar 

Owen OE. Mini-series: paths to discovery. Keton bodies as fuel for the brain during starvation. Biochem Mol Biol Educ. 2005;33:246–51.

Article  CAS  Google Scholar 

Munro JF, Maccuish AC, Goodall JA, Fraser J, Duncan LJ. Further experience with prolon- ged therapeutic starvation in gross refractory obesity. Br Med J. 1970;4:712–4.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Runcie J, Thomson TJ. Prolonged starvation–a dangerous procedure? Br Med J. 1970;3:432–5.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Thomson TJ, Runcie J, Miller V. Treatment of obesity by total fasting for up to 249 days. Lancet. 1966;2:992–6.

Article  CAS  PubMed  Google Scholar 

Bloom WL. Fasting as an introduction to the treatment of obesity. Metabolism. 1959;8:214–20.

CAS  PubMed  Google Scholar 

Duncan GG, Jenson WK, Fraser RI, Cristofori FC. Correction and control of intractable obesity. Practicable application of intermittent periods of total fasting. JAMA. 1962;181:309–12.

Article  CAS  PubMed  Google Scholar 

Drenick EJ, Swendseid ME, Blahd WH, Tuttle SG. Prolonged starvation as treatment for severe obesity. JAMA. 1964;187:100–5.

Article  CAS  PubMed  Google Scholar 

Cahill GF Jr. Starvation in man. N. Engl J Med. 1970;282:668–75.

Article  CAS  PubMed  Google Scholar 

Stewart WK, Fleming LW. Features of a successful therapeutic fast of 382 days’ duration. Postgrad Med J. 1973;49:203–9.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cahill GF Jr. Fuel metabolism in starvation. Annu Rev Nutr. 2006;26:1–22.

Article  CAS  PubMed  Google Scholar 

Owen OE, Felig P, Morgan AP, Wahren J, Cahill GF Jr. Liver and kidney metabolism during prolonged starvation. J Clin Invest. 1969;48:574–83.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cori CF, Cori GT. Carbohydrate metabolism. Annu Rev Biochem. 1946;15:193–218.

Article  CAS  PubMed  Google Scholar 

Brooks GA. The science and translation of lactate shuttle theory. Cell Metab. 2018;27:757–85.

Article  CAS  PubMed  Google Scholar 

Bergman BC, Wolfel EE, Butterfield GE, Lopaschuk GD, Casazza GA, Horning MA, et al. Active muscle and whole body lactate kinetics after endurance training in men. J Appl Physiol. 1999;87:1684–96.

Article  CAS  PubMed  Google Scholar 

Stanley WC, Gertz EW, Wisneski JA, Neese RA, Morris DL, Brooks GA. Lactate extraction during net lactate release in legs of humans during exercise. J Appl Physiol. 1986;60:1116–20.

Article  CAS  PubMed  Google Scholar 

Bergman BC, Tsvetkova T, Lowes B, Wolfel EE. Myocardial glucose and lactate metabolism during rest and atrial pacing in humans. J Physiol. 2009;587:2087–99.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gertz EW, Wisneski JA, Stanley WC, Neese RA. Myocardial substrate utilization during exercise in humans. Dual carbon-labeled carbohydrate isotope experiments. J Clin Invest. 1988;82:2017–25.

Article  CAS  PubMed  PubMed Central  Google Scholar 

van Hall G, Stromstad M, Rasmussen P, Jans O, Zaar M, Gam C, et al. Blood lactate is an important energy source for the human brain. J Cereb Blood Flow Metab. 2009;29:1121–9.

Article  PubMed  Google Scholar 

Glenn TC, Martin NA, Horning MA, McArthur DL, Hovda DA, Vespa P, et al. Lactate: brain fuel in human traumatic brain injury: a comparison with normal healthy control subjects. J Neurotrauma. 2015;32:820–32.

Article  PubMed  PubMed Central  Google Scholar 

Bergman BC, Horning MA, Casazza GA, Wolfel EE, Butterfield GE, Brooks GA. Endurance training increases gluconeogenesis during rest and exercise in men. Am J Physiol Endocrinol Metab. 2000;278:E244–51.

Article  CAS  PubMed  Google Scholar 

Emhoff CA, Messonnier LA, Horning MA, Fattor JA, Carlson TJ, Brooks GA. Gluconeogenesis and hepatic glycogenolysis during exercise at the lactate threshold. J Appl Physiol. 2013;114:297–306.

Article  CAS  PubMed  Google Scholar 

Laffel L. Ketone bodies: a review of physiology, pathophysiology and application of monitoring to diabetes. Diabetes Metab Res Rev. 1999;15:412–26.

Article  CAS  PubMed  Google Scholar 

Owen OE, Reichard GA Jr. Human forearm metabolism during progressive starvation. J Clin Invest. 1971;50:1536–45.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hagenfeldt L, Wahren J. Human forearm muscle metabolism during exercise. VI. Substrate utilization in prolonged fasting. Scand J Clin Lab Invest. 1971;27:299–306.

Comments (0)

No login
gif