Zilberberg MD, Nathanson BH, Ways J, Shorr AF. Characteristics, hospital course, and outcomes of patients requiring prolonged acute versus short-term mechanical ventilation in the United States, 2014–2018. Crit Care Med. 2020;48:1587–94.

Article  PubMed  Google Scholar 

Wunsch H, Linde-Zwirble WT, Angus DC, Hartman ME, Milbrandt EB, Kahn JM. The epidemiology of mechanical ventilation use in the United States. Crit Care Med. 2010;38:1947–53.

Article  PubMed  Google Scholar 

Marmor M, Liu S, Long J, Chertow GM, Rogers AJ. Prolonged hospitalization following acute respiratory failure. Chest. 2021;159:1867–74.

Article  PubMed  Google Scholar 

Rodrigues A, Telias I, Damiani LF, Brochard L. Reverse triggering during controlled ventilation: from physiology to clinical management. Am J Respir Crit Care Med. 2023;207:533–43.

Article  PubMed  Google Scholar 

de Haro C, Ochagavia A, López-Aguilar J, Fernandez-Gonzalo S, Navarra-Ventura G, Magrans R, et al. Patient-ventilator asynchronies during mechanical ventilation: current knowledge and research priorities. Intensive Care Med Exp. 2019;7:43.

Article  PubMed  PubMed Central  Google Scholar 

Papazian L, Forel JM, Gacouin A, Penot-Ragon C, Perrin G, Loundou A, et al. Neuromuscular blockers in early acute respiratory distress syndrome. N Engl J Med. 2010;363:1107–16.

Article  CAS  PubMed  Google Scholar 

Slutsky AS. Neuromuscular blocking agents in ARDS. N Engl J Med. 2010;363:1176–80.

Article  CAS  PubMed  Google Scholar 

Wang W, Xu C, Ma X, Zhang X, Xie P. Intensive care unit-acquired weakness: a review of recent progress with a look toward the future. Front Med (Lausanne). 2020;7: 559789.

Article  PubMed  Google Scholar 

Levine S, Nguyen T, Taylor N, Friscia ME, Budak MT, Rothenberg P, et al. Rapid disuse atrophy of diaphragm fibers in mechanically ventilated humans. N Engl J Med. 2008;358:1327–35.

Article  CAS  PubMed  Google Scholar 

Hooijman PE, Beishuizen A, Witt CC, de Waard MC, Girbes AR, Spoelstra-de Man AM, et al. Diaphragm muscle fiber weakness and ubiquitin-proteasome activation in critically ill patients. Am J Respir Crit Care Med. 2015;191:1126–38.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Murray MJ, DeBlock H, Erstad B, Gray A, Jacobi J, Jordan C, et al. Clinical practice guidelines for sustained neuromuscular blockade in the adult critically ill patient. Crit Care Med. 2016;44:2079–103.

Article  CAS  PubMed  Google Scholar 

Evans L, Rhodes A, Alhazzani W, Antonelli M, Coopersmith CM, French C, et al. Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021. Intensive Care Med. 2021;47:1181–247.

Article  PubMed  PubMed Central  Google Scholar 

Alhazzani W, Belley-Cote E, Møller MH, Angus DC, Papazian L, Arabi YM, et al. Neuromuscular blockade in patients with ARDS: a rapid practice guideline. Intensive Care Med. 2020;46:1977–86.

Article  PubMed  PubMed Central  Google Scholar 

Hsing AW, Ioannidis JP. Nationwide population science: lessons from the Taiwan National Health Insurance Research Database. JAMA Intern Med. 2015;175:1527–9.

Article  PubMed  Google Scholar 

Moss M, Huang DT, Brower RG, Ferguson ND, Ginde AA, Gong MN, et al. Early neuromuscular blockade in the acute respiratory distress syndrome. N Engl J Med. 2019;380:1997–2008.

Article  PubMed  Google Scholar 

Urner M, Jüni P, Hansen B, Wettstein MS, Ferguson ND, Fan E. Time-varying intensity of mechanical ventilation and mortality in patients with acute respiratory failure: a registry-based, prospective cohort study. Lancet Respir Med. 2020;8:905–13.

Article  PubMed  PubMed Central  Google Scholar 

Esteban A, Frutos-Vivar F, Muriel A, Ferguson ND, Peñuelas O, Abraira V, et al. Evolution of mortality over time in patients receiving mechanical ventilation. Am J Respir Crit Care Med. 2013;188:220–30.

Article  PubMed  Google Scholar 

Wilson ME, Barwise A, Heise KJ, Loftsgard TO, Dziadzko M, Cheville A, et al. Long-term return to functional baseline after mechanical ventilation in the ICU. Crit Care Med. 2018;46:562–9.

Article  PubMed  Google Scholar 

Herridge MS, Chu LM, Matte A, Tomlinson G, Chan L, Thomas C, et al. The RECOVER program: disability risk groups and 1-year outcome after 7 or more days of mechanical ventilation. Am J Respir Crit Care Med. 2016;194:831–44.

Article  PubMed  Google Scholar 

Damuth E, Mitchell JA, Bartock JL, Roberts BW, Trzeciak S. Long-term survival of critically ill patients treated with prolonged mechanical ventilation: a systematic review and meta-analysis. Lancet Respir Med. 2015;3:544–53.

Article  PubMed  Google Scholar 

Wang CY, Calfee CS, Paul DW, Janz DR, May AK, Zhuo H, et al. One-year mortality and predictors of death among hospital survivors of acute respiratory distress syndrome. Intensive Care Med. 2014;40:388–96.

Article  PubMed  PubMed Central  Google Scholar 

Oh TK, Song IA. Trends in mortality, treatment, and costs of management of acute respiratory distress syndrome in South Korea: analysis of data between 2010 and 2019. Yonsei Med J. 2022;63:452–60.

Article  PubMed  PubMed Central  Google Scholar 

Herridge MS, Tansey CM, Matté A, Tomlinson G, Diaz-Granados N, Cooper A, et al. Functional disability 5 years after acute respiratory distress syndrome. N Engl J Med. 2011;364:1293–304.

Article  CAS  PubMed  Google Scholar 

Parhar KKS, Zjadewicz K, Soo A, Sutton A, Zjadewicz M, Doig L, et al. Epidemiology, mechanical power, and 3-year outcomes in acute respiratory distress syndrome patients using standardized screening. An observational cohort study. Ann Am Thorac Soc. 2019;16:1263–72.

Article  PubMed  PubMed Central  Google Scholar 

Dinglas VD, Aronson Friedman L, Colantuoni E, Mendez-Tellez PA, Shanholtz CB, Ciesla ND, et al. Muscle weakness and 5-year survival in acute respiratory distress syndrome survivors. Crit Care Med. 2017;45:446–53.

Article  PubMed  PubMed Central  Google Scholar 

Fazzini B, Battaglini D, Carenzo L, Pelosi P, Cecconi M, Puthucheary Z. Physical and psychological impairment in survivors of acute respiratory distress syndrome: a systematic review and meta-analysis. Br J Anaesth. 2022;129:801–14.

Article  PubMed  Google Scholar 

Torbic H, Krishnan S, Harnegie MP, Duggal A. Neuromuscular blocking agents for ARDS: a systematic review and meta-analysis. Respir Care. 2021;66:120–8.

Article  PubMed  Google Scholar 

Tarazan N, Alshehri M, Sharif S, Al Duhailib Z, Møller MH, Belley-Cote E, et al. Neuromuscular blocking agents in acute respiratory distress syndrome: updated systematic review and meta-analysis of randomized trials. Intensive Care Med Exp. 2020;8:61.

Article  PubMed  PubMed Central  Google Scholar 

Shao S, Kang H, Tong Z. Early neuromuscular blocking agents for adults with acute respiratory distress syndrome: a systematic review, meta-analysis and meta-regression. BMJ Open. 2020;10: e037737.

Article  PubMed  PubMed Central  Google Scholar 

Li Bassi G, Gibbons K, Suen JY, Dalton HJ, White N, Corley A, et al. Early short course of neuromuscular blocking agents in patients with COVID-19 ARDS: a propensity score analysis. Crit Care. 2022;26:141.

Article  PubMed  PubMed Central  Google Scholar 

Sharshar T, Bastuji-Garin S, Stevens RD, Durand MC, Malissin I, Rodriguez P, et al. Presence and severity of intensive care unit-acquired paresis at time of awakening are associated with increased intensive care unit and hospital mortality. Crit Care Med. 2009;37:3047–53.

Article  PubMed  Google Scholar 

Price DR, Mikkelsen ME, Umscheid CA, Armstrong EJ. Neuromuscular blocking agents and neuromuscular dysfunction acquired in critical illness: a systematic review and meta-analysis. Crit Care Med. 2016;44:2070–8.

Article  CAS  PubMed  Google Scholar 

Yang T, Li Z, Jiang L, Wang Y, Xi X. Risk factors for intensive care unit-acquired weakness: a systematic review and meta-analysis. Acta Neurol Scand. 2018;138:104–14.

Article  PubMed  Google Scholar 

Schepens T, Verbrugghe W, Dams K, Corthouts B, Parizel PM, Jorens PG. The course of diaphragm atrophy in ventilated patients assessed with ultrasound: a longitudinal cohort study. Crit Care. 2015;19:422.

Article  PubMed  PubMed Central  Google Scholar 

Goligher EC, Dres M, Fan E, Rubenfeld GD, Scales DC, Herridge MS, et al. Mechanical ventilation-induced diaphragm atrophy strongly impacts clinical outcomes. Am J Respir Crit Care Med. 2018;197:204–13.

Article  CAS  PubMed  Google Scholar 

Dres M, Goligher EC, Heunks LMA, Brochard LJ. Critical illness-associated diaphragm weakness. Intensive Care Med. 2017;43:1441–52.

Article  PubMed  Google Scholar 

Vanhorebeek I, Latronico N, Van den Berghe G. ICU-acquired weakness. Intensive Care Med. 2020;46:637–53.

Article  PubMed  PubMed Central