Association of glycemic variability with death and severe consciousness disturbance among critically ill patients with cerebrovascular disease: analysis of the MIMIC-IV database

Hu X, De Silva TM, Chen J, Faraci FM. Cerebral vascular Disease and Neurovascular Injury in ischemic Stroke. Circ Res. 2017;120(3):449–71.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Levine DA, Chen B, Galecki AT, Gross AL, Briceño EM, Whitney RT, Ploutz-Snyder RJ, Giordani BJ, Sussman JB, Burke JF, et al. Associations between vascular risk factor levels and cognitive decline among Stroke survivors. JAMA Netw Open. 2023;6(5):e2313879.

Article  PubMed  PubMed Central  Google Scholar 

Levine DA, Galecki AT, Langa KM, Unverzagt FW, Kabeto MU, Giordani B, Wadley VG. Trajectory of cognitive decline after Incident Stroke. JAMA. 2015;314(1):41–51.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chang CWJ, Provencio JJ, Shah S. Neurological critical care: the evolution of cerebrovascular critical care. Crit Care Med. 2021;49(6):881–900.

Article  PubMed  Google Scholar 

Harshfield EL, Markus HS. Association of Baseline Metabolomic profiles with Incident Stroke and Dementia and with imaging markers of Cerebral Small Vessel Disease. Neurology. 2023;101(5):e489–e501.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yamada T, Shojima N, Hara K, Noma H, Yamauchi T, Kadowaki T. Glycemic control, mortality, secondary Infection, and hypoglycemia in critically ill pediatric patients: a systematic review and network meta-analysis of randomized controlled trials. Intensive Care Med. 2017;43(9):1427–9.

Article  PubMed  Google Scholar 

Bohé J, Abidi H, Brunot V, Klich A, Klouche K, Sedillot N, Tchenio X, Quenot JP, Roudaut JB, Mottard N, et al. Individualised versus conventional glucose control in critically-ill patients: the CONTROLING study-a randomized clinical trial. Intensive Care Med. 2021;47(11):1271–83.

PubMed  PubMed Central  Google Scholar 

Takahashi H, Iwahashi N, Kirigaya J, Kataoka S, Minamimoto Y, Gohbara M, Abe T, Okada K, Matsuzawa Y, Konishi M, et al. Glycemic variability determined with a continuous glucose monitoring system can predict prognosis after acute coronary syndrome. Cardiovasc Diabetol. 2018;17(1):116.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hanajima Y, Iwahashi N, Kirigaya J, Horii M, Minamimoto Y, Gohbara M, Abe T, Okada K, Matsuzawa Y, Kosuge M, et al. Prognostic importance of glycemic variability on left ventricular reverse remodeling after the first episode of ST-segment elevation Myocardial Infarction. Cardiovasc Diabetol. 2023;22(1):202.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ceriello A, Monnier L, Owens D. Glycaemic variability in Diabetes: clinical and therapeutic implications. Lancet Diabetes Endocrinol. 2019;7(3):221–30.

Article  PubMed  Google Scholar 

Krinsley JS, Grover A. Severe hypoglycemia in critically ill patients: risk factors and outcomes. Crit Care Med. 2007;35(10):2262–7.

Article  PubMed  Google Scholar 

Bagshaw SM, Bellomo R, Jacka MJ, Egi M, Hart GK, George C. The impact of early hypoglycemia and blood glucose variability on outcome in critical Illness. Crit Care. 2009;13(3):R91.

Article  PubMed  PubMed Central  Google Scholar 

Echouffo-Tcheugui JB, Zhao S, Brock G, Matsouaka RA, Kline D, Joseph JJ. Visit-to-visit Glycemic Variability and risks of Cardiovascular events and all-cause mortality: the ALLHAT Study. Diabetes Care. 2019;42(3):486–93.

Article  PubMed  PubMed Central  Google Scholar 

Mitsios JP, Ekinci EI, Mitsios GP, Churilov L, Thijs V. Relationship between glycated hemoglobin and Stroke risk: a systematic review and Meta-analysis. J Am Heart Assoc 2018, 7(11).

Xu Y, Dong S, Fu EL, Sjölander A, Grams ME, Selvin E, Carrero JJ. Long-term visit-to-visit variability in Hemoglobin A(1c) and kidney-related outcomes in persons with Diabetes. Am J Kidney Dis 2023.

Pouryousefi E, Javadi M, Hashemipour S, Nooshabadi MR, Haghighian HK. Improved glycemic status, insulin resistance and inflammation after receiving oral oleoylethanolamide supplement in people with prediabetes: a randomized controlled trial. Diabetol Metab Syndr. 2022;14(1):77.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Mohandes S, Doke T, Hu H, Mukhi D, Dhillon P, Susztak K. Molecular pathways that drive diabetic Kidney Disease. J Clin Invest 2023, 133(4).

Nuthikattu S, Milenkovic D, Norman JE, Rutledge J, Villablanca A. Inhibition of Soluble Epoxide hydrolase is protective against the Multiomic effects of a high Glycemic Diet on Brain Microvascular inflammation and cognitive dysfunction. Nutrients 2021, 13(11).

Taylor MK, Sullivan DK, Swerdlow RH, Vidoni ED, Morris JK, Mahnken JD, Burns JM. A high-glycemic diet is associated with cerebral amyloid burden in cognitively normal older adults. Am J Clin Nutr. 2017;106(6):1463–70.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gentreau M, Raymond M, Chuy V, Samieri C, Féart C, Berticat C, Artero S. High glycemic load is Associated with Cognitive decline in apolipoprotein E ε4 allele carriers. Nutrients 2020, 12(12).

Ceriello A, Esposito K, Piconi L, Ihnat MA, Thorpe JE, Testa R, Boemi M, Giugliano D. Oscillating glucose is more deleterious to endothelial function and oxidative stress than mean glucose in normal and type 2 diabetic patients. Diabetes. 2008;57(5):1349–54.

Article  CAS  PubMed  Google Scholar 

McCrimmon RJ, Ryan CM, Frier BM. Diabetes and cognitive dysfunction. Lancet. 2012;379(9833):2291–9.

Article  PubMed  Google Scholar 

Bergenstal RM. Glycemic variability and Diabetes Complications: does it Matter? Simply put, there are better glycemic markers! Diabetes Care. 2015;38(8):1615–21.

Article  PubMed  Google Scholar 

Hirsch IB. Glycemic variability and Diabetes Complications: does it Matter? Of Course it does! Diabetes Care. 2015;38(8):1610–4.

Article  CAS  PubMed  Google Scholar 

Johnson AEW, Bulgarelli L, Shen L, Gayles A, Shammout A, Horng S, Pollard TJ, Hao S, Moody B, Gow B, et al. MIMIC-IV, a freely accessible electronic health record dataset. Sci Data. 2023;10(1):1.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Caprio FZ, Sorond FA. Cerebrovascular Disease: primary and secondary Stroke Prevention. Med Clin North Am. 2019;103(2):295–308.

Article  PubMed  Google Scholar 

Grant PJ, Cosentino F. The 2019 ESC guidelines on diabetes, pre-diabetes, and Cardiovascular Diseases developed in collaboration with the EASD: new features and the ‘Ten commandments’ of the 2019 guidelines are discussed by Professor Peter J. Grant and Professor Francesco Cosentino, the Task Force chairmen. Eur Heart J. 2019;40(39):3215–7.

Article  PubMed  Google Scholar 

Meschia JF, Bushnell C, Boden-Albala B, Braun LT, Bravata DM, Chaturvedi S, Creager MA, Eckel RH, Elkind MS, Fornage M et al. Guidelines for the primary prevention of stroke: a statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke 2014, 45(12):3754–3832.

Sarwar N, Gao P, Seshasai SR, Gobin R, Kaptoge S, Di Angelantonio E, Ingelsson E, Lawlor DA, Selvin E, Stampfer M, et al. Diabetes Mellitus, fasting blood glucose concentration, and risk of vascular Disease: a collaborative meta-analysis of 102 prospective studies. Lancet. 2010;375(9733):2215–22.

Article  CAS  PubMed  Google Scholar 

Chang JY, Kim WJ, Kwon JH, Lee JS, Kim BJ, Kim JT, Lee J, Cha JK, Kim DH, Cho YJ, et al. Association of Prestroke Glycemic Control with vascular events during 1-Year follow-up. Neurology. 2021;97(17):e1717–26.

Article  CAS  PubMed  Google Scholar 

Rawlings AM, Sharrett AR, Mosley TH, Ballew SH, Deal JA, Selvin E. Glucose peaks and the risk of Dementia and 20-Year cognitive decline. Diabetes Care. 2017;40(7):879–86.

Article  CAS  PubMed  PubMed Central  Google Scholar 

He J, Li S, Liu F, Zheng H, Yan X, Xie Y, Li X, Zhou Z, Zhu X. Glycemic control is related to cognitive dysfunction in Chinese children with type 1 Diabetes Mellitus. J Diabetes. 2018;10(12):948–57.

Article  PubMed  Google Scholar 

Lheureux O, Prevedello D, Preiser JC. Update on glucose in critical care. Nutrition. 2019;59:14–20.

Article  CAS  PubMed  Google Scholar 

Doola R, Greer RM, Hurford R, Flatley C, Forbes JM, Todd AS, Joyce CJ, Sturgess DJ. Glycaemic variability and its association with enteral and parenteral nutrition in critically ill ventilated patients. Clin Nutr. 2019;38(4):1707–12.

Article  PubMed  Google Scholar 

Russo VC, Higgins S, Werther GA, Cameron FJ. Effects of fluctuating glucose levels on neuronal cells in vitro. Neurochem Res. 2012;37(8):1768–82.

Article  CAS  PubMed  Google Scholar 

Rizzo MR, Marfella R, Barbieri M, Boccardi V, Vestini F, Lettieri B, Canonico S, Paolisso G. Relationships between daily acute glucose fluctuations and cognitive performance among aged type 2 diabetic patients. Diabetes Care. 2010;33(10):2169–74.

Article  PubMed  PubMed Central  Google Scholar 

Mo Y, Wang C, Lu J, Shen Y, Chen L, Zhang L, Lu W, Zhu W, Xia T, Zhou J. Impact of short-term glycemic variability on risk of all-cause mortality in type 2 Diabetes patients with well-controlled glucose profile by continuous glucose monitoring: a prospective cohort study. Diabetes Res Clin Pract. 2022;189:109940.

Article  CAS  PubMed  Google Scholar 

Cai J, Yang Q, Lu J, Shen Y, Wang C, Chen L, Zhang L, Lu W, Zhu W, Xia T, et al. Impact of the complexity of glucose Time Series on all-cause mortality in patients with type 2 Diabetes. J Clin Endocrinol Metab. 2023;108(5):1093–100.

Article  PubMed  Google Scholar 

Ma H, Yu G, Wang Z, Zhou P, Lv W. Association between dysglycemia and mortality by Diabetes status and risk factors of dysglycemia in critically ill patients: a retrospective study. Acta Diabetol. 2022;59(4):461–70.

Article  CAS  PubMed  Google Scholar 

Gerbaud E, Bouchard de La Poterie A, Baudinet T, Montaudon M, Beauvieux MC, Lemaître AI, Cetran L, Seguy B, Picard F, Vélayoudom FL et al. Glycaemic variability and hyperglycaemia as prognostic markers of Major Cardiovascular events in Diabetic patients Hospitalised in Cardiology Intensive Care Unit for Acute Heart Failure. J Clin Med 2022, 11(6).

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