Targeting ferroptosis in hepatocellular carcinoma

Sung H, et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021;71(3):209–249

Article  PubMed  Google Scholar 

Siegel RL, et al. Cancer statistics, 2022. CA Cancer J Clin. 2022;72(1):7–33

Article  PubMed  Google Scholar 

Pinna AD, et al. Liver transplantation and hepatic resection can achieve cure for hepatocellular carcinoma. Ann Surg. 2018;268(5):868–875

Article  PubMed  Google Scholar 

Wang K, et al. Combination of ablation and immunotherapy for hepatocellular carcinoma: where we are and where to go. Front Immunol. 2021;12: 792781

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zheng J, et al. Actual 10-year survivors after resection of hepatocellular carcinoma. Ann Surg Oncol. 2017;24(5):1358–1366

Article  PubMed  Google Scholar 

Bodzin AS, et al. Predicting mortality in patients developing recurrent hepatocellular carcinoma after liver transplantation: impact of treatment modality and recurrence characteristics. Ann Surg. 2017;266(1):118–125

Article  PubMed  Google Scholar 

Shimizu R, et al. Feeding artery ablation before radiofrequency ablation for hepatocellular carcinoma may reduce critical recurrence. JGH Open. 2021;5(4):478–485

Article  PubMed  PubMed Central  Google Scholar 

Raoul JL, et al. Updated use of TACE for hepatocellular carcinoma treatment: How and when to use it based on clinical evidence. Cancer Treat Rev. 2019;72:28–36

Article  CAS  PubMed  Google Scholar 

Li QJ, et al. Hepatic arterial infusion of oxaliplatin, fluorouracil, and leucovorin versus transarterial chemoembolization for large hepatocellular carcinoma: a randomized phase III trial. J Clin Oncol. 2022;40(2):150–160

Article  CAS  PubMed  Google Scholar 

Jin Q, Chen X, Zheng S. The security rating on local ablation and interventional therapy for hepatocellular carcinoma (HCC) and the comparison among multiple anesthesia methods. Anal Cell Pathol (Amst). 2019;2019:2965173

PubMed  Google Scholar 

Xu J, et al. Anti-PD-1 antibody SHR-1210 combined with apatinib for advanced hepatocellular carcinoma, gastric, or esophagogastric junction cancer: an open-label, dose escalation and expansion study. Clin Cancer Res. 2019;25(2):515–523

Article  CAS  PubMed  Google Scholar 

Finn RS, et al. Atezolizumab plus bevacizumab in unresectable hepatocellular carcinoma. N Engl J Med. 2020;382(20):1894–1905

Article  CAS  PubMed  Google Scholar 

Oura K, et al. Tumor immune microenvironment and immunosuppressive therapy in hepatocellular carcinoma: a review. Int J Mol Sci. 2021;22:11

Article  Google Scholar 

Fu Y, et al. From bench to bed: the tumor immune microenvironment and current immunotherapeutic strategies for hepatocellular carcinoma. J Exp Clin Cancer Res. 2019;38(1):396

Article  PubMed  PubMed Central  Google Scholar 

Zheng C, et al. Landscape of infiltrating T cells in liver cancer revealed by single-cell sequencing. Cell. 2017;169(7):1342–1356

Article  CAS  PubMed  Google Scholar 

Abbott M, Ustoyev Y. Cancer and the immune system: the history and background of immunotherapy. Semin Oncol Nurs. 2019;35(5): 150923

Article  PubMed  Google Scholar 

Velcheti V, Schalper K. Basic overview of current immunotherapy approaches in cancer. Am Soc Clin Oncol Educ Book. 2016;35:298–308

Article  PubMed  Google Scholar 

Yap TA, et al. Development of immunotherapy combination strategies in cancer. Cancer Discov. 2021;11(6):1368–1397

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wang T, et al. Comprehensive molecular analyses of a macrophage-related gene signature with regard to prognosis, immune features, and biomarkers for immunotherapy in hepatocellular carcinoma based on WGCNA and the LASSO algorithm. Front Immunol. 2022;13: 843408

Article  CAS  PubMed  PubMed Central  Google Scholar 

Carneiro BA, El-Deiry WS. Targeting apoptosis in cancer therapy. Nat Rev Clin Oncol. 2020;17(7):395–417

Article  PubMed  PubMed Central  Google Scholar 

Yu T, et al. MT1JP-mediated miR-24-3p/BCL2L2 axis promotes Lenvatinib resistance in hepatocellular carcinoma cells by inhibiting apoptosis. Cell Oncol (Dordr). 2021;44(4):821–834

Article  CAS  PubMed  Google Scholar 

Yang JR, Ling XL, Guan QL. RAP2A promotes apoptosis resistance of hepatocellular carcinoma cells via the mTOR pathway. Clin Exp Med. 2021;21(4):545–554

Article  CAS  PubMed  Google Scholar 

Wang Q, et al. COX-2 induces apoptosis-resistance in hepatocellular carcinoma cells via the HIF-1alpha/PKM2 pathway. Int J Mol Med. 2019;43(1):475–488

PubMed  Google Scholar 

Yang T, et al. Selenium sulfide disrupts the PLAGL2/C-MET/STAT3-induced resistance against mitochondrial apoptosis in hepatocellular carcinoma. Clin Transl Med. 2021;11(9): e536

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dixon SJ, et al. Ferroptosis: an iron-dependent form of nonapoptotic cell death. Cell. 2012;149(5):1060–1072

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li J, et al. Ferroptosis: past, present and future. Cell Death Dis. 2020;11(2):88

Article  PubMed  PubMed Central  Google Scholar 

Ursini F, Maiorino M. Lipid peroxidation and ferroptosis: the role of GSH and GPx4. Free Radic Biol Med. 2020;152:175–185

Article  CAS  PubMed  Google Scholar 

Chen X, et al. Ferroptosis: machinery and regulation. Autophagy. 2021;17(9):2054–2081

Article  CAS  PubMed  Google Scholar 

Liang D, Minikes AM, Jiang X. Ferroptosis at the intersection of lipid metabolism and cellular signaling. Mol Cell. 2022;82(12):2215–2227

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li Y, et al. Erastin induces ferroptosis via ferroportin-mediated iron accumulation in endometriosis. Hum Reprod. 2021;36(4):951–964

Article  CAS  PubMed  Google Scholar 

Chen X, et al. Ferroptosis and cardiovascular disease: role of free radical-induced lipid peroxidation. Free Radic Res. 2021;55(4):405–415

Article  CAS  PubMed  Google Scholar 

Lee JY, et al. Polyunsaturated fatty acid biosynthesis pathway determines ferroptosis sensitivity in gastric cancer. Proc Natl Acad Sci U S A. 2020;117(51):32433–32442

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhang HL, et al. PKCbetaII phosphorylates ACSL4 to amplify lipid peroxidation to induce ferroptosis. Nat Cell Biol. 2022;24(1):88–98

Article  CAS  PubMed  Google Scholar 

Chen X, et al. Broadening horizons: the role of ferroptosis in cancer. Nat Rev Clin Oncol. 2021;18(5):280–296

Article  CAS  PubMed  Google Scholar 

Zhao L, et al. Ferroptosis in cancer and cancer immunotherapy. Cancer Commun (Lond). 2022;42(2):88–116

Article  PubMed  PubMed Central  Google Scholar 

Chen Y, et al. CRISPR screens uncover protective effect of PSTK as a regulator of chemotherapy-induced ferroptosis in hepatocellular carcinoma. Mol Cancer. 2022;21(1):11

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lei G, et al. Ferroptosis, radiotherapy, and combination therapeutic strategies. Protein Cell. 2021;12(11):836–857

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lal A. Iron in health and disease: an update. Indian J Pediatr. 2020;87(1):58–65

Article  PubMed  Google Scholar 

Shang Y, et al. Ceruloplasmin suppresses ferroptosis by regulating iron homeostasis in hepatocellular carcinoma cells. Cell Signal. 2020;72: 109633

Article  CAS  PubMed  Googl

留言 (0)

沒有登入
gif