Maternal adverse childhood experiences (ACEs) and DNA methylation of newborns in cord blood

CDC National Center for Injury Prevention and Control, Division of Violence Prevention. Fast Facts: Preventing Adverse Childhood Experiences [Internet]. 2023. Available from: https://www.cdc.gov/violenceprevention/aces/fastfact.html

Giano Z, Wheeler DL, Hubach RD. The frequencies and disparities of adverse childhood experiences in the U.S. BMC Public Health. 2020;20:1327.

Article  PubMed  PubMed Central  Google Scholar 

Kidman R, Piccolo LR, Kohler H-P. Adverse childhood experiences: prevalence and association with adolescent health in Malawi. Am J Prev Med. 2020;58:285–93.

Article  PubMed  Google Scholar 

LaBrenz CA, O’Gara JL, Panisch LS, Baiden P, Larkin H. Adverse childhood experiences and mental and physical health disparities: the moderating effect of race and implications for social work. Soc Work Health Care. 2020;59:588–614.

Article  PubMed  Google Scholar 

Soares S, Rocha V, Kelly-Irving M, Stringhini S, Fraga S. Adverse childhood events and health biomarkers: a systematic review. Front Public Health. 2021;9:649825.

Article  PubMed  PubMed Central  Google Scholar 

Nelson CA, Scott RD, Bhutta ZA, Harris NB, Danese A, Samara M. Adversity in childhood is linked to mental and physical health throughout life. BMJ. 2020;371:m3048.

Article  PubMed  PubMed Central  Google Scholar 

Hughes K, Bellis MA, Hardcastle KA, Sethi D, Butchart A, Mikton C, et al. The effect of multiple adverse childhood experiences on health: a systematic review and meta-analysis. Lancet Public Health. 2017;2:e356–66.

Article  PubMed  Google Scholar 

Petruccelli K, Davis J, Berman T. Adverse childhood experiences and associated health outcomes: a systematic review and meta-analysis. Child Abuse Negl. 2019;97:104127.

Article  PubMed  Google Scholar 

Sonu S, Post S, Feinglass J. Adverse childhood experiences and the onset of chronic disease in young adulthood. Prev Med. 2019;123:163–70.

Article  PubMed  Google Scholar 

Bellis MA, Hughes K, Ford K, Ramos Rodriguez G, Sethi D, Passmore J. Life course health consequences and associated annual costs of adverse childhood experiences across Europe and North America: a systematic review and meta-analysis. Lancet Public Health. 2019;4:e517–28.

Article  PubMed  PubMed Central  Google Scholar 

Hofheimer JA, McGrath M, Musci R, Wu G, Polk S, Blackwell CK, et al. Assessment of psychosocial and neonatal risk factors for trajectories of behavioral dysregulation among young children from 18 to 72 months of age. JAMA Netw Open. 2023;6:e2310059–e2310059.

Article  PubMed  PubMed Central  Google Scholar 

Miller ES, Fleming O, Ekpe EE, Grobman WA, Heard-Garris N. Association between adverse childhood experiences and adverse pregnancy outcomes. Obstet Gynecol. 2021;138:770–6.

Article  PubMed  PubMed Central  Google Scholar 

Racine N, Devereaux C, Cooke JE, Eirich R, Zhu J, Madigan S. Adverse childhood experiences and maternal anxiety and depression: a meta-analysis. BMC Psychiatry. 2021;21:28.

Article  PubMed  PubMed Central  Google Scholar 

Racine N, Plamondon A, Madigan S, McDonald S, Tough S. Maternal adverse childhood experiences and infant development. Pediatrics. 2018;141:e20172495.

Article  PubMed  Google Scholar 

McDonald SW, Madigan S, Racine N, Benzies K, Tomfohr L, Tough S. Maternal adverse childhood experiences, mental health, and child behaviour at age 3: the all our families community cohort study. Prev Med. 2019;118:286–94.

Article  CAS  PubMed  Google Scholar 

Madigan S, Wade M, Plamondon A, Maguire JL, Jenkins JM. Maternal adverse childhood experience and infant health: biomedical and psychosocial risks as intermediary mechanisms. J Pediatr. 2017;187:282-289.e1.

Article  PubMed  Google Scholar 

Currie CL, Tough SC. Adverse childhood experiences are associated with illicit drug use among pregnant women with middle to high socioeconomic status: findings from the All Our Families Cohort. BMC Pregnancy Childbirth. 2021;21:133.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Nwanaji-Enwerem JC, Van Der Laan L, Kogut K, Eskenazi B, Holland N, Deardorff J, et al. Maternal adverse childhood experiences before pregnancy are associated with epigenetic aging changes in their children. Aging. 2021;13:25653–69.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Esteves KC, Jones CW, Wade M, Callerame K, Smith AK, Theall KP, et al. Adverse childhood experiences: implications for offspring telomere length and psychopathology. Am J Psychiatry. 2020;177:47–57.

Article  PubMed  Google Scholar 

Jawaid A, Roszkowski M, Mansuy IM. Chapter Twelve—Transgenerational Epigenetics of Traumatic Stress. In: Rutten BPF, editor. Prog Mol Biol Transl Sci [Internet]. Academic Press; 2018. p. 273–98. Available from: https://www.sciencedirect.com/science/article/pii/S187711731830053X

Saavedra-Rodríguez L, Feig LA. Chronic social instability induces anxiety and defective social interactions across generations. Struct Funct Act Stress Anxiety. 2013;73:44–53.

Google Scholar 

Gapp K, Jawaid A, Sarkies P, Bohacek J, Pelczar P, Prados J, et al. Implication of sperm RNAs in transgenerational inheritance of the effects of early trauma in mice. Nat Neurosci. 2014;17:667–9.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lacal I, Ventura R. Epigenetic inheritance: concepts, mechanisms and perspectives. Front Mol Neurosci [Internet]. 2018;11. Available from: https://www.frontiersin.org/article/10.3389/fnmol.2018.00292

Polinski KJ, Putnick DL, Robinson SL, Schliep KC, Silver RM, Guan W, et al. Periconception and prenatal exposure to maternal perceived stress and cord blood DNA methylation. Epigenet Insights. 2022;15:25168657221082044.

Article  Google Scholar 

Brunst KJ, Tignor N, Just A, Liu Z, Lin X, Hacker MR, et al. Cumulative lifetime maternal stress and epigenome-wide placental DNA methylation in the PRISM cohort. Epigenetics. 2018;13:665–81.

Article  PubMed  PubMed Central  Google Scholar 

Kotsakis Ruehlmann A, Sammallahti S, Cortés Hidalgo AP, Bakulski KM, Binder EB, Campbell ML, et al. Epigenome-wide meta-analysis of prenatal maternal stressful life events and newborn DNA methylation. Mol Psychiatry. 2023;

Houtepen LC, Hardy R, Maddock J, Kuh D, Anderson EL, Relton CL, et al. Childhood adversity and DNA methylation in two population-based cohorts. Transl Psychiatry. 2018;8:266.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Scorza P, Duarte CS, Lee S, Wu H, Posner J, Baccarelli A, et al. Epigenetic intergenerational transmission: mothers’ adverse childhood experiences and DNA methylation. J Am Acad Child Adolesc Psychiatry. 2023;S0890–8567(23):00313–21.

Google Scholar 

Moore SR, Merrill SM, Sekhon B, MacIsaac JL, Kobor MS, Giesbrecht GF, et al. Infant DNA methylation: an early indicator of intergenerational trauma? Early Hum Dev. 2022;164:105519.

Article  CAS  PubMed  Google Scholar 

Folger AT, Nidey N, Ding L, Ji H, Yolton K, Ammerman RT, et al. Association between maternal adverse childhood experiences and neonatal SCG5 DNA methylation-effect modification by prenatal home visiting. Am J Epidemiol. 2022;191:636–45.

Article  PubMed  Google Scholar 

Grasso DJ, Drury S, Briggs-Gowan M, Johnson A, Ford J, Lapidus G, et al. Adverse childhood experiences, posttraumatic stress, and FKBP5 methylation patterns in postpartum women and their newborn infants. Psychoneuroendocrinology. 2020;114:104604.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Eskenazi B, Bradman A, Gladstone EA, Jaramillo S, Birch K, Holland N. CHAMACOS, a longitudinal birth cohort study: lessons from the fields. J Child Health. 2003;1:3–27.

Article  Google Scholar 

Felitti VJ, Anda RF, Nordenberg D, Williamson DF, Spitz AM, Edwards V, et al. Relationship of childhood abuse and household dysfunction to many of the leading causes of death in adults. The Adverse Childhood Experiences (ACE) Study. Am J Prev Med. 1998;14:245–58.

Article  CAS  PubMed  Google Scholar 

Storey JD, Tibshirani R. Statistical significance for genomewide studies. Proc Natl Acad Sci. 2003;100:9440.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Battram B, Yousefi P, Crawford G, Prince C, Babaei MS, Sharp G, et al. The EWAS Catalog: a database of epigenome-wide association studies [version 2; peer review: 2 approved]. Wellcome Open Res. 2022;7:41.

Article  PubMed  PubMed Central  Google Scholar 

Spiers H, Hannon E, Schalkwyk LC, Smith R, Wong CCY, O’Donovan MC, et al. Methylomic trajectories across human fetal brain development. Genome Res. 2015;25:338–52.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Mulder RH, Neumann A, Cecil CAM, Walton E, Houtepen LC, Simpkin AJ, et al. Epigenome-wide change and variation in DNA methylation in childhood: trajectories from birth to late adolescence. Hum Mol Genet. 2021;30:119–34.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Pedersen BS, Schwartz DA, Yang IV, Kechris KJ. Comb-p: software for combining, analyzing, grouping and correcting spatially correlated p values. Bioinformatics. 2012;28:2986–8.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Langfelder P, Horvath S. WGCNA: an R package for weighted correlation network analysis. BMC Bioinf. 2008;9:559.

Article  Google Scholar 

Kanehisa M, Goto S. KEGG: Kyoto encyclopedia of genes and genomes. Nucleic Acids Res. 2000;28:27–30.

Article  CAS 

留言 (0)

沒有登入
gif