Bodily J, Laimins LA. Persistence of human papillomavirus infection: keys to malignant progression. Trends Microbiol. 2011;19(1):33–9.

Article  PubMed  CAS  Google Scholar 

Mirabello L, Yeager M, Yu K, Clifford GM, Xiao Y, Zhu B, et al. HPV16 E7 genetic conservation is critical to carcinogenesis. Cell. 2017;170(6):1164–74.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Yim EK, Park JS. The role of HPV E6 and E7 oncoproteins in HPV-associated cervical carcinogenesis. Cancer Res Treat Off J Korean Cancer Assoc. 2005;37(6):319–24.

Google Scholar 

Yang W, Song Y, Lu Y, Sun J, Wang H. Increased expression of programmed death (PD)-1 and its ligand PD-L1 correlates with impaired cell-mediated immunity in high-risk human papillomavirus-related cervical intraepithelial neoplasia. Immunology. 2013;139(4):513–22.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Muñoz N, Castellsagué X, de González AB, Gissmann L. HPV in the etiology of human cancer. Vaccine. 2006;24:S1-10.

Article  Google Scholar 

Romanczuk H, Howley PM. Disruption of either the E1 or the E2 regulatory gene of human papillomavirus type 16 increases viral immortalization capacity. Proc Natl Acad Sci. 1992;89(7):3159–63.

Article  ADS  PubMed  PubMed Central  CAS  Google Scholar 

Narisawa-Saito M, Kiyono T. Basic mechanisms of high-risk human papillomavirus-induced carcinogenesis: roles of E6 and E7 proteins. Cancer Sci. 2007;98(10):1505–11.

Article  PubMed  CAS  Google Scholar 

Amiri BS, Sabernia N, Nassaj ZS, Boustani H, Rezaeeyan H. Evaluation of MicroRNA as Minimal Residual Disease in Leukemia: Diagnostic and Prognostic Approach: A Review. Iran J Public Health. 2023;52(12):2541–53.

PubMed  PubMed Central  Google Scholar 

Goodarzi V, Nouri S, Nassaj ZS, Bighash M, Abbasian S, Hagh RA. Long non coding RNAs reveal important pathways in childhood asthma: a future perspective. J Mol Histol. 2023;54(4):257–69.

Article  PubMed  CAS  Google Scholar 

Xie L, Yao Z, Zhang Y, Li D, Hu F, Liao Y, et al. Deep RNA sequencing reveals the dynamic regulation of miRNA, lncRNAs, and mRNAs in osteosarcoma tumorigenesis and pulmonary metastasis. Cell Death Dis. 2018;9(7):772.

Article  PubMed  PubMed Central  Google Scholar 

Sharma S, Munger K. The role of long noncoding RNAs in human papillomavirus-associated pathogenesis. Pathogens. 2020;9(4):289.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Modabber N, Mahboub SS, Khoshravesh S, Karimpour F, Karimi A, Goodarzi V. Evaluation of long non-coding RNA (LncRNA) in the pathogenesis of chemotherapy resistance in cervical cancer: diagnostic and prognostic approach. Mol Biotechnol. 2023. https://doi.org/10.1007/s12033-023-00909-6.

Article  PubMed  Google Scholar 

Hull R, Mbita Z, Dlamini Z. Long non-coding RNAs (LncRNAs), viral oncogenomics, and aberrant splicing events: therapeutics implications. Am J Cancer Res. 2021;11(3):866.

PubMed  PubMed Central  CAS  Google Scholar 

Sharma S, Mandal P, Sadhukhan T, Roy Chowdhury R, Ranjan Mondal N, Chakravarty B, et al. Bridging links between long noncoding RNA HOTAIR and HPV oncoprotein E7 in cervical cancer pathogenesis. Sci Rep. 2015;5(1):1–15.

Article  CAS  Google Scholar 

Choi H, Lee S, Lee M, Park D, Choi SS. Investigation of the putative role of antisense transcripts as regulators of sense transcripts by correlation analysis of sense-antisense pairs in colorectal cancers. FASEB J. 2021;35(4): e21482.

Article  PubMed  CAS  Google Scholar 

Fang Y, Fullwood MJ. Roles, functions, and mechanisms of long non-coding RNAs in cancer. Genomics Proteomics Bioinform. 2016;14(1):42–54.

Article  CAS  Google Scholar 

Balbin OA, Malik R, Dhanasekaran SM, Prensner JR, Cao X, Wu YM, et al. The landscape of antisense gene expression in human cancers. Genome Res. 2015;25(7):1068–79.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Halley P, Khorkova O, Wahlestedt C. Natural antisense transcripts as therapeutic targets. Drug Discov Today Ther Strateg. 2013;10(3): e119.

Article  PubMed  PubMed Central  Google Scholar 

Ghosh A, Sinha A, Ghosh A, Roy S, Mallick S, Kumar V, et al. Prognostic relevance of correlated co-expression of coding and noncoding RNAs in cervical cancers. bioRxiv.[Preprint] 2023. https://doi.org/10.1101/2023.12.28.573593.

Overmeer RM, Louwers JA, Meijer CJ, van Kemenade FJ, Hesselink AT, Daalmeijer NF, et al. Combined CADM1 and MAL promoter methylation analysis to detect (pre-) malignant cervical lesions in high-risk HPV-positive women. Int J Cancer. 2011;129(9):2218–25.

Article  PubMed  CAS  Google Scholar 

Del Pino M, Sierra A, Marimon L, Martí Delgado C, Rodriguez-Trujillo A, Barnadas E, et al. CADM1, MAL, and miR124 promoter methylation as biomarkers of transforming cervical intrapithelial lesions. Int J Mol Sci. 2019;20(9):2262.

Article  PubMed  PubMed Central  Google Scholar 

Labat-de-Hoz L, Rubio-Ramos A, Correas I, Alonso MA. The MAL family of proteins: normal function, expression in cancer, and potential use as cancer biomarkers. Cancers. 2023;15(10):2801.

Article  PubMed  PubMed Central  CAS  Google Scholar 

van Baars R, van der Marel J, Snijders PJ, Rodriquez-Manfredi A, ter Harmsel B, van den Munckhof HA, et al. CADM1 and MAL methylation status in cervical scrapes is representative of the most severe underlying lesion in women with multiple cervical biopsies. Int J Cancer. 2016;138(2):463–71.

Article  PubMed  Google Scholar 

Hesselink AT, Heideman DA, Steenbergen RD, Coupé VM, Overmeer RM, Rijkaart D, et al. Combined promoter methylation analysis of CADM1 and MAL: an objective triage tool for high-risk human papillomavirus DNA–positive women. Clin Cancer Res. 2011;17(8):2459–65.

Article  PubMed  CAS  Google Scholar 

De Vuyst H, Franceschi S, Plummer M, Mugo NR, Sakr SR, Meijer CJ, et al. Methylation levels of CADM1, MAL, and MIR124-2 in cervical scrapes for triage of HIV-infected, high-risk HPV-positive women in Kenya. J Acquir Immune Defic Syndr. 2015;70(3):311–8.

Article  PubMed  Google Scholar 

Meršaková S, Holubeková V, Grendár M, Višňovský J, Ňachajová M, Kalman M, et al. Methylation of CADM1 and MAL together with HPV status in cytological cervical specimens serves an important role in the progression of cervical intraepithelial neoplasia. Oncol Lett. 2018;16(6):7166–74.

PubMed  PubMed Central  Google Scholar 

De Strooper LM, Hesselink AT, Berkhof J, Meijer CJ, Snijders PJ, Steenbergen RD, et al. Combined CADM1/MAL methylation and cytology testing for colposcopy triage of high-risk HPV-positive women. Cancer Epidemiol Biomarkers Prev. 2014;23(9):1933–7.

Article  PubMed  Google Scholar 

Phillips S, Cassells K, Garland SM, Machalek DA, Roberts JM, Templeton DJ, et al. Gene methylation of CADM1 and MAL identified as a biomarker of high grade anal intraepithelial neoplasia. Sci Rep. 2022;12(1):3565.

Article  ADS  PubMed  PubMed Central  CAS  Google Scholar 

Rubio-Ramos A, Labat-de-Hoz L, Correas I, Alonso MA. The MAL protein, an integral component of specialized membranes, in normal cells and cancer. Cells. 2021;10(5):1065.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Gan L, Yang Y, Li Q, Feng Y, Liu T, Guo W. Epigenetic regulation of cancer progression by EZH2: from biological insights to therapeutic potential. Biomark Res. 2018;6(1):1–10.

Article  Google Scholar 

O’Geen H, Echipare L, Farnham PJ. Using ChIP-seq technology to generate high-resolution profiles of histone modifications. Epigenetics Protoc. 2011;791:265–86.

Article  Google Scholar 

Liu X, Liu X. PRC2, chromatin regulation, and human disease: Insights from molecular structure and function. Front Oncol. 2022;12: 894585.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Bellucci M, Agostini F, Masin M, Tartaglia GG. Predicting protein associations with long noncoding RNAs. Nat Methods. 2011;8(6):444–5.

Article  PubMed  CAS  Google Scholar 

Wang S, Zuo H, Jin J, Lv W, Xu Z, Fan Y, et al. Long noncoding RNA Neat1 modulates myogenesis by recruiting Ezh2. Cell Death Dis. 2019;10(7):505.

Article  PubMed  PubMed Central  Google Scholar 

McLaughlin-Drubin ME, Crum CP, Münger K. Human papillomavirus E7 oncoprotein induces KDM6A and KDM6B histone demethylase expression and causes epigenetic reprogramming. Proc Natl Acad Sci. 2011;108(5):2130–5.

Article  ADS  PubMed  PubMed Central  CAS  Google Scholar 

Yap KL, Li S, Muñoz-Cabello AM, Raguz S, Zeng L, Mujtaba S, et al. Molecular interplay of the noncoding RNA ANRIL and methylated histone H3 lysine 27 by polycomb CBX7 in transcriptional silencing of INK4a. Mol Cell. 2010;38(5):662–74.

Article  PubMed  PubMed Central  CAS  Google Scholar