Hew-Butler T, Rosner MH, Fowkes-Godek S, Dugas JP, Hoffman MD, Lewis DP, Maughan RJ, Miller KC, Montain SJ, Rehrer NJ, Roberts WO, Rogers IR, Siegel AJ, Stuempfle KJ, Winger JM, Verbalis JG (2015) Statement of the third international Exercise-Associated Hyponatremia Consensus Development Conference, Carlsbad, California, 2015. Clin J Sport Med 25(4):303–320. https://doi.org/10.1097/JSM.0000000000000221
Verbalis JG (2007) Renal function and vasopressin during marathon running. Sports Med 37(4–5):455–458. https://doi.org/10.2165/00007256-200737040-00048
Hew-Butler T, Jordaan E, Stuempfle KJ, Speedy DB, Siegel AJ, Noakes TD, Soldin SJ, Verbalis JG (2008) Osmotic and nonosmotic regulation of arginine vasopressin during prolonged endurance exercise. J Clin Endocrinol Metab 93(6):2072–2078. https://doi.org/10.1210/jc.2007-2336
Article PubMed PubMed Central CAS Google Scholar
Hew-Butler T, Dugas JP, Noakes TD, Verbalis JG (2010) Changes in plasma arginine vasopressin concentrations in cyclists participating in a 109-km cycle race. Br J Sports Med 44(8):594–597. https://doi.org/10.1136/bjsm.2008.049742
Article PubMed CAS Google Scholar
Cairns RS, Hew-Butler T (2015) Incidence of exercise-associated hyponatremia and its association with nonosmotic stimuli of arginine vasopressin in the GNW100s ultra-endurance marathon. Clin J Sport Med 25(4):347–354. https://doi.org/10.1097/JSM.0000000000000144
Hew-Butler T (2019) Exercise-associated hyponatremia. Front Horm Res 52:178–189. https://doi.org/10.1159/000493247
Article PubMed CAS Google Scholar
Ayus JC, Varon J, Arieff AI (2000) Hyponatremia, cerebral edema, and noncardiogenic pulmonary edema in marathon runners. Ann Intern Med 132(9):711–714. https://doi.org/10.7326/0003-4819-132-9-200005020-00005
Article PubMed CAS Google Scholar
M Sawka, M.N Burke, L.M Eichner, E.R Maughan, R.J Montain, S.J Stachenfeld. N.S.: American College of Sports Medicine position stand. Exercise and fluid replacement. Med Sci Sports Exerc. 2007.39(2) 377–390. https://doi.org/10.1249/mss.0b013e31802ca597
Klingert M, Nikolaidis P.T., Weiss, K., Thuany, M., Chlibkova, D., Knechtle, B.: Exercise-Associated Hyponatremia in Marathon Runners. J Clin Med. 2022.11 (22). https://doi.org/10.3390/jcm11226775
Reid SA, Speedy DB, Thompson JM, Noakes TD, Mulligan G, Page T, Campbell RG, Milne C (2004) Study of hematological and biochemical parameters in runners completing a standard marathon. Clin J Sport Med 14(6):344–353. https://doi.org/10.1097/00042752-200411000-00004
Almond CS, Shin AY, Fortescue EB, Mannix RC, Wypij D, Binstadt BA, Duncan CN, Olson DP, Salerno AE, Newburger JW, Greenes DS (2005) Hyponatremia among runners in the Boston Marathon. N Engl J Med 352(15):1550–1556. https://doi.org/10.1056/NEJMoa043901
Article PubMed CAS Google Scholar
Danz M, Pottgen K, Tonjes PM, Hinkelbein J, Braunecker S (2016) Hyponatremia among triathletes in the Ironman European Championship. N Engl J Med 374(10):997–998. https://doi.org/10.1056/NEJMc1510409
Bradshaw CJ, Bundy M, Falvey E (2008) The diagnosis of longstanding groin pain: a prospective clinical cohort study. Br J Sports Med 42(10):851–854. https://doi.org/10.1136/bjsm.2007.039685
Article PubMed CAS Google Scholar
Cohen D (2012) The truth about sports drinks. BMJ 345:e4737. https://doi.org/10.1136/bmj.e4737
Changstrom B, Brill J, Hecht S (2017) Severe exercise-associated hyponatremia in a collegiate American football player. Curr Sports Med Rep 16(5):343–345. https://doi.org/10.1249/JSR.0000000000000399
Elsaesser TF, Pang PS, Malik S, Chiampas GT (2013) Large-volume hypertonic saline therapy in endurance athlete with exercise-associated hyponatremic encephalopathy. J Emerg Med 44(6):1132–1135. https://doi.org/10.1016/j.jemermed.2012.11.048
Bennett BL, Hew-Butler T, Rosner MH, Myers T, Lipman GS (2020) Wilderness medical society clinical practice guidelines for the management of exercise-associated hyponatremia: 2019 update. Wilderness Environ Med 31(1):50–62. https://doi.org/10.1016/j.wem.2019.11.003
Oh RC, Galer M, Bursey MM (2018) Found in the field - a soldier with heat stroke, exercise-associated hyponatremia, and kidney injury. Curr Sports Med Rep 17(4):123–125. https://doi.org/10.1249/JSR.0000000000000471
Kipps C, Sharma S, Tunstall Pedoe D (2011) The incidence of exercise-associated hyponatraemia in the London Marathon. Br J Sports Med 45(1):14–19. https://doi.org/10.1136/bjsm.2009.059535
Mayer CU, Treff G, Fenske WK, Blouin K, Steinacker JM, Allolio B (2015) High incidence of hyponatremia in rowers during a four-week training camp. Am J Med 128(10):1144–1151. https://doi.org/10.1016/j.amjmed.2015.04.014
Article PubMed CAS Google Scholar
Mohseni M, Silvers S, McNeil R, Diehl N, Vadeboncoeur T, Taylor W, Shapiro S, Roth J, Mahoney S (2011) Prevalence of hyponatremia, renal dysfunction, and other electrolyte abnormalities among runners before and after completing a marathon or half marathon. Sports Health 3(2):145–151. https://doi.org/10.1177/1941738111400561
Article PubMed PubMed Central Google Scholar
Armstrong LE, Lee EC, Casa DJ, Johnson EC, Ganio MS, McDermott BP, Vingren JL, Oh HM, Williamson KH (2017) Exertional hyponatremia and serum sodium change during ultraendurance cycling. Int J Sport Nutr Exerc Metab 27(2):139–147. https://doi.org/10.1123/ijsnem.2016-0135
Article PubMed CAS Google Scholar
Jones BL, O’Hara JP, Till K, King RF (2015) Dehydration and hyponatremia in professional rugby union players: a cohort study observing English premiership rugby union players during match play, field, and gym training in cool environmental conditions. J Strength Cond Res 29(1):107–115. https://doi.org/10.1519/JSC.0000000000000620
Bridges E, Altherwi T, Correa JA, Hew-Butler T (2020) Oral hypertonic saline is effective in reversing acute mild-to-moderate symptomatic exercise-associated hyponatremia. Clin J Sport Med 30(1):8–13. https://doi.org/10.1097/JSM.0000000000000573
Oh RC, Malave B, Chaltry JD (2018) Collapse in the heat - from overhydration to the emergency room - three cases of exercise-associated hyponatremia associated with exertional heat illness. Mil Med 183(3–4):e225–e228. https://doi.org/10.1093/milmed/usx105
Buck E, McAllister R, Schroeder JD (2024) Exercise-Associated Hyponatremia. In: StatPearls. Treasure Island (FL) ineligible companies. Disclosure: Rebecca McAllister declares no relevant financial relationships with ineligible companies. Disclosure: Jeremy Schroeder declares no relevant financial relationships with ineligible companies.
Payne M (2014) A high school football player dies after reportedly consuming two gallons each of water and Gatorade. https://www.washingtonpost.com/news/early-lead/wp/2014/08/13/a-high-school-football-player-dies-after-reportedly-consuming-two-gallons-each-of-water-and-gatorade/. Accessed 20/10/2024
Hew-Butler T, Loi V, Pani A, Rosner MH (2017) Exercise-Associated Hyponatremia: 2017 Update. Front Med (Lausanne) 4:21. https://doi.org/10.3389/fmed.2017.00021
Krabel, H.: Athlete dies after IM Frankfurt. https://www.slowtwitch.com/news/athlete-dies-after-im-frankfurt/. 2015.
Baumgarder, A.: Au Sable River Canoe Marathon Pushes Paddlers to the Limits. https://www.mlive.com/sports/bay-city/2009/07/au_sable_river_canoe_marathon.html. 2009.
Garigan TP, Ristedt DE (1999) Death from hyponatremia as a result of acute water intoxication in an Army basic trainee. Mil Med 164(3):234–238
Article PubMed CAS Google Scholar
Nolte HW, Hew-Butler T, Noakes TD, Duvenage CS (2015) Exercise-associated hyponatremic encephalopathy and exertional heatstroke in a soldier: high rates of fluid intake during exercise caused rather than prevented a fatal outcome. Phys Sportsmed 43(1):93–98. https://doi.org/10.1080/00913847.2015.1001714
Chorley J, Cianca J, Divine J (2007) Risk factors for exercise-associated hyponatremia in non-elite marathon runners. Clin J Sport Med 17(6):471–477. https://doi.org/10.1097/JSM.0b013e3181588790
Knechtle B, Chlibkova D, Papadopoulou S, Mantzorou M, Rosemann T, Nikolaidis PT (2019) Exercise-associated hyponatremia in endurance and ultra-endurance performance-aspects of sex, race location, ambient temperature, sports discipline, and length of performance: a narrative review. Medicina (Kaunas). https://doi.org/10.3390/medicina55090537
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