Central hypothyroidism and cardiovascular disease: a Spanish cohort observational study

Persani L, Cangiano B, Bonomi M (2018) The diagnosis and management of central hypothyroidism in 2018. Endocr Connect 8:R44–R54. https://doi.org/10.1530/EC-18-0515

Article  Google Scholar 

Ross DS (2024) Central hypothyroidism. http://www.uptodate.com. Accessed june, 2024

Grunenwald S, Caron P (2015) Central hypothyroidism in adults: better Understanding for better care. Pituitary 18:169–175. https://doi.org/10.1007/s11102-014-0559-8

Article  CAS  PubMed  Google Scholar 

Iglesias P (2025) Central hypothyroidism: advances in etiology, diagnostic challenges, therapeutic targets, and associated risks. Endocr Pract 31:650–659. https://doi.org/10.1016/j.eprac.2025.02.004

Article  CAS  PubMed  Google Scholar 

Beck-Peccoz P, Rodari G, Giavoli C, Lania A (2017) Central hypothyroidism - a neglected thyroid disorder. Nat Rev Endocrinol 13:588–598. https://doi.org/10.1038/nrendo.2017.47

Article  CAS  PubMed  Google Scholar 

Feldt-Rasmussen U, Effraimidis G, Klose M (2021) The hypothalamus-pituitary-thyroid (HPT)-axis and its role in physiology and pathophysiology of other hypothalamus-pituitary functions. Mol Cell Endocrinol 5:111173. https://doi.org/10.1016/j.mce.2021.111173

Article  CAS  Google Scholar 

Udovcic M, Pena RH, Patham B, Tabatabai L, Kansara A (2017) Hypothyroidism and the heart. Methodist Debakey Cardiovasc J 13:55–59. https://doi.org/10.14797/mdcj-13-2-55

Article  PubMed  PubMed Central  Google Scholar 

Liu D, Jiang F, Shan Z et al (2010) A cross-sectional survey of relationship between serum TSH level and blood pressure. J Hum Hypertens 24:134–138. https://doi.org/10.1038/jhh.2009.44

Article  CAS  PubMed  Google Scholar 

Poudel S, Angolkar M, Maldar A (2023) Diabetes among patients with overt primary hypothyroidism visiting the outpatient department of general medicine of a tertiary care centre: A descriptive Cross-sectional study. JNMA J Nepal Med Assoc 61:421–423. https://doi.org/10.31729/jnma.8161

Article  PubMed  PubMed Central  Google Scholar 

Treister-Goltzman Y, Yarza S, Peleg R (2022) Lipid profile in mild subclinical hypothyroidism: systematic review and meta-analysis. Minerva Endocrinol (Torino) 46:428–440. https://doi.org/10.23736/S2724-6507.20.03197-1

Article  Google Scholar 

Mahzari MM, Alserehi AH, Almutairi SA, Alanazi KH, Alharbi MA, Mohamud M (2022) Hypothyroidism and the risk of coronary artery disease in Saudi patients. J Family Community Med 29:34–40. https://doi.org/10.4103/jfcm.jfcm_368_21

Article  PubMed  PubMed Central  Google Scholar 

Ro K, Yuen AD, Du L et al (2018) Impact of hypothyroidism and heart failure on hospitalization risk. Thyroid 28:1094–1100. https://doi.org/10.1089/thy.2017.0362

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yang MH, Yang FY, Lee DD (2015) Thyroid disease as a risk factor for cerebrovascular disease. J Stroke Cerebrovasc Dis 24:912–920. https://doi.org/10.1016/j.jstrokecerebrovasdis.2014.11.032

Article  PubMed  Google Scholar 

Feldt-Rasmussen U, Klose M (2016) Central hypothyroidism and its role for cardiovascular risk factors in hypopituitary patients. Endocrine 54:15–23. https://doi.org/10.1007/s12020-016-1047-x

Article  CAS  PubMed  Google Scholar 

Ebrahimi F, Christ E (2023) Why do patients with hypopituitarism still present an increased mortality? Ann Endocrinol (Paris) 84:285–290. https://doi.org/10.1016/j.ando.2023.02.002

Article  PubMed  Google Scholar 

McEvoyJW, McCarthy CP, Bruno RM et al (2024) 2024 ESC guidelines for the management of elevated blood pressure and hypertension. G Ital Cardiol (Rome) 25e1–e107. https://doi.org/10.1093/eurheartj/ehae178

Authors/Task Force Members; ESC Committee for Practice Guidelines (CPG); ESC National Cardiac Societies (2019) 2019 ESC/EAS guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk. Atherosclerosis 290:140–205. https://doi.org/10.1016/j.atherosclerosis.2019.08.014

Article  CAS  Google Scholar 

American Diabetes Association Professional Practice Committee (2024) 2. Diagnosis and classification of diabetes: standards of care in Diabetes-2024. Diabetes Care 47:S20–S42. https://doi.org/10.2337/dc24-S002

Article  Google Scholar 

Yumuk V, Tsigos C, Fried M et al (2015) Obesity management task force of the European association for the study of obesity. European guidelines for obesity.management in adults. Obes Facts 8:402–424. https://doi.org/10.2337/dc24-S002

Article  PubMed  PubMed Central  Google Scholar 

Byrne RA, Rossello X, Coughlan JJ, ESC Scientific Document Group (2023). 2023 ESC Guidelines for the management of acute coronary syndromes. G Ital Cardiol (Rome) 25:e1-e112. https://doi.org/10.1714/4191.41785

Vrints C, Andreotti F, Koskinas KC et al (2024) ESC scientific document group. 2024 ESC guidelines for the management of chronic coronary syndromes. Eur Heart J 45:3415–3537. https://doi.org/10.1714/4375.43725

Article  CAS  PubMed  Google Scholar 

McDonagh TA, Metra M, Adamo M, ESC Scientific Document Group (2021). 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. Eur Heart J 42:3599–3726. https://doi.org/10.1016/j.rec.2022.05.005

Van Gelder IC, Rienstra M, Bunting KV, ESC Scientific Document Group (2024) 2024 ESC guidelines for the management of atrial fibrillation developed in collaboration with the European association for Cardio-Thoracic surgery (EACTS). Eur Heart J 45:3314–3414. https://doi.org/10.1093/eurheartj/ehae176

Article  PubMed  Google Scholar 

Ortel TL, Neumann I, Ajeno W et al (2020) American society of hematology 2020 guidelines for management of venous thromboembolism: treatment of deep vein thrombosis and pulmonary embolism. Blood Adv 4:4693–4738. https://doi.org/10.1182/bloodadvances.2020001830

Article  CAS  PubMed  PubMed Central  Google Scholar 

Powers WJ, Rabinstein AA, Ackerson T et al (2019) Guidelines for the early management of patients with acute ischemic stroke: 2019 update to the 2018 guidelines for the early management of acute ischemic stroke: A guideline for healthcare professionals from the American heart association/american stroke association. Stroke 50:e344–e418. https://doi.org/10.1161/STR.0000000000000211

Article  PubMed  Google Scholar 

Mazzolai L, Teixido-Tura G, Lanzi S, ESC Scientific Document Group (2024) 2024 ESC guidelines for the management of peripheral arterial and aortic diseases. Eur Heart J 45:3538–3700. https://doi.org/10.1093/eurheartj/ehae179

Article  PubMed  Google Scholar 

IBM Corp (2017) IBM SPSS statistics for windows, version 25.0. IBM Corp, Armonk, NY

Google Scholar 

Baena-Díez JM, Félix FJ, Grau M et al (2011) Risk factor treatment and control in relation to coronary disease risk in the Spanish population of the DARIOS study. Rev Esp Cardiol 64:766–673. https://doi.org/10.1016/j.recesp.2011.04.019

Article  PubMed  Google Scholar 

Aranceta-Bartrina J, Pérez-Rodrigo C, Alberdi-Aresti G, Ramos-Carrera N, Lázaro-Masedo S (2016) Prevalence of general obesity and abdominal obesity in the Spanish adult population (Aged 25–64 Years) 2014–2015: the ENPE study. Rev Esp Cardiol (Engl Ed) 69:579–587. https://doi.org/10.1016/j.rec.2016.02.009

Article  PubMed  Google Scholar 

Rey-Brandariz J, Ruano-Ravina A, Santiago-Pérez MI et al (2024) Evolution of smoking prevalence in Spain and its 17 autonomous regions (1987–2020). Med Clin (Barc) 162:417–424. https://doi.org/10.1016/j.medcli.2023.11.015

Article  PubMed  Google Scholar 

Chaker L, Razvi S, Bensenor IM, Azizi F, Pearce EN, Peeters RP (2022) Hypothyroidism. Nat Rev Dis Primers 8:30. https://doi.org/10.1038/s41572-022-00357-7

Article  PubMed  Google Scholar 

Taylor PN, Albrecht D, Scholz A, Gutierrez-Buey G, Lazarus JH, Dayan CM, Okosieme OE (2018) Global epidemiology of hyperthyroidism and hypothyroidism. Nat Rev Endocrinol 14:301–316. https://doi.org/10.1038/nrendo.2018.18

Article  PubMed  Google Scholar 

Cappola AR, Ladenson PW (2003) Hypothyroidism and atherosclerosis. J Clin Endocrinol Metab 88:2438–2444. https://doi.org/10.1210/jc.2003-030398

Article  CAS  PubMed  Google Scholar 

Alamdari S, Amouzegar A, Tohidi M et al (2015) Hypothyroidism and lipid levels in a community based study (TTS). Int J Endocrinol Metab 14:e22827. https://doi.org/10.5812/ijem.22827

Article 

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