Siegel RL, Giaquinto AN, Jemal A (2024) Cancer statistics, 2024 [published correction appears in CA Cancer J Clin. 2024 Mar-Apr;74(2):203]. CA Cancer J Clin 74(1):12–49
Mohanty SK, Lobo A, Cheng L (2023) The 2022 revision of the world health organization classification of tumors of the urinary system and male genital organs: advances and challenges. Hum Pathol 136:123–143
Blum KA, Gupta S, Tickoo SK, Chan TA, Russo P, Motzer RJ, Karam JA, Hakimi AA (2020) Sarcomatoid renal cell carcinoma: biology, natural history and management. Nat Rev Urol 17(12):659–678
Article CAS PubMed PubMed Central Google Scholar
Wang Z, Kim TB, Peng B et al (2017) Sarcomatoid renal cell carcinoma has a distinct molecular pathogenesis, driver mutation profile, and transcriptional landscape. Clin Cancer Res 23(21):6686–6696
Article CAS PubMed PubMed Central Google Scholar
Bakouny Z, Braun DA, Shukla SA et al (2021) Integrative molecular characterization of sarcomatoid and rhabdoid renal cell carcinoma. Nat Commun 12(1):808
Article CAS PubMed PubMed Central Google Scholar
Lucarelli G, Lasorsa F, Milella M et al Transcriptomic and proteo-metabolic determinants of the grading system in clear cell renal cell carcinoma. Urol Oncol. Mar 12:S1078-1439(25)00065– 1. Epub ahead of print
Adibi M, Thomas AZ, Borregales LD, Merrill MM, Slack RS, Chen HC, Sircar K, Murugan P, Tamboli P, Jonasch E, Tannir NM, Matin SF, Wood CG, Karam JA (2015) Percentage of sarcomatoid component as a prognostic indicator for survival in renal cell carcinoma with sarcomatoid dedifferentiation. Urol Oncol 427.e17-23
Kim T, Zargar-Shoshtari K, Dhillon J, Lin HY, Yue B, Fishman M, Sverrisson EF, Spiess PE, Gupta S, Poch MA, Sexton WJ (2015) Using percentage of sarcomatoid differentiation as a prognostic factor in renal cell carcinoma. Clin Genitourin Cancer 13(3):225–230
Zhang BY, Thompson RH, Lohse CM, Leibovich BC, Boorjian SA, Cheville JC, Costello BA (2015) A novel prognostic model for patients with sarcomatoid renal cell carcinoma. BJU Int 115(3):405–411
Salgia NJ, Aubrecht WM, Wang L, Ram B, Wasik BJ, Khan A, Attwood K, Daza J, Long MD, Eng KH, Xu B, Muhitch JB, Kauffman EC (2024) Stratification of patients with renal cell carcinoma by the abundance of sarcomatoid features reveals differences in survival and the underlying pathobiology. Eur Urol Oncol 7(5):973–977
Subramanian A, Tamayo P, Mootha VK et al (2005) Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci U S A 102(43):15545–15550
Article CAS PubMed PubMed Central Google Scholar
Lasorsa F, Rutigliano M, Milella M, Ferro M, Pandolfo SD, Crocetto F, Simone S, Gesualdo L, Battaglia M, Ditonno P, Lucarelli G (2023) Complement system and the kidney: its role in renal diseases, kidney transplantation and renal cell carcinoma. Int J Mol Sci 24(22):16515
Article CAS PubMed PubMed Central Google Scholar
Lucarelli G, Netti GS, Rutigliano M, Lasorsa F, Loizzo D, Milella M, Schirinzi A, Fontana A, Di Serio F, Tamma R, Ribatti D, Battaglia M, Ranieri E, Ditonno P (2023) MUC1 Expression Affects the Immunoflogosis in Renal Cell Carcinoma Microenvironment through Complement System Activation and Immune Infiltrate Modulation. Int J Mol Sci. Mar 2;24(5):4814
Netti GS, Lucarelli G, Spadaccino F, Castellano G, Gigante M, Divella C, Rocchetti MT, Rascio F, Mancini V, Stallone G, Carrieri G, Gesualdo L, Battaglia M, Ranieri E PTX3 modulates the immunoflogosis in tumor microenvironment and is a prognostic factor for patients with clear cell renal cell carcinoma. (2020) aging (Albany NY). 12(8):7585–7602
di Meo NA, Lasorsa F, Rutigliano M, Loizzo D, Ferro M, Stella A, Bizzoca C, Vincenti L, Pandolfo SD, Autorino R, Crocetto F, Montanari E, Spilotros M, Battaglia M, Ditonno P, Lucarelli G (2022) Renal cell carcinoma as a metabolic disease: an update on main pathways, potential biomarkers, and therapeutic targets. Int J Mol Sci 23(22):14360
Article PubMed PubMed Central Google Scholar
Lucarelli G, Ferro M, Loizzo D, Bianchi C, Terracciano D, Cantiello F, Bell LN, Battaglia S, Porta C, Gernone A, Perego RA, Maiorano E, Cobelli O, Castellano G, Vincenti L, Ditonno P, Battaglia M (2020) Integration of Lipidomics and Transcriptomics Reveals Reprogramming of the Lipid Metabolism and Composition in Clear Cell Renal Cell Carcinoma. Metabolites10(12):509
Lasorsa F, di Meo NA, Rutigliano M, Milella M, Ferro M, Pandolfo SD, Crocetto F, Tataru OS, Autorino R, Battaglia M, Ditonno P, Lucarelli G (2023) Immune checkpoint inhibitors in renal cell carcinoma: molecular basis and rationale for their use in clinical practice. Biomedicines 11(4):1071
Article CAS PubMed PubMed Central Google Scholar
Motzer RJ, Banchereau R, Hamidi H, Powles T, McDermott D, Atkins MB, Escudier B, Liu LF, Leng N, Abbas AR, Fan J, Koeppen H, Lin J, Carroll S, Hashimoto K, Mariathasan S, Green M, Tayama D, Hegde PS, Schiff C, Huseni MA, Rini B (2020) Molecular subsets in renal Cancer determine outcome to checkpoint and angiogenesis Blockade. Cancer Cell 38(6):803–817e4
Article CAS PubMed PubMed Central Google Scholar
Lasorsa F, Rutigliano M, Milella M, Ferro M, Pandolfo SD, Crocetto F, Tataru OS, Autorino R, Battaglia M, Ditonno P, Lucarelli G (2023) Cellular and molecular players in the tumor microenvironment of renal cell carcinoma. J Clin Med 12(12):3888
Comments (0)