Delpino FM, Figueiredo LM (2021 Nov-Dec) Melatonin supplementation and anthropometric indicators of obesity: A systematic review and meta-analysis. Nutrition 91–92:111399. https://doi.org/10.1016/j.nut.2021.111399Epub 2021 Jun 24. PMID: 34626955

Chitimus DM, Popescu MR, Voiculescu SE, Panaitescu AM, Pavel B, Zagrean L, Zagrean AM (2020) Melatonin’s impact on antioxidative and Anti-Inflammatory reprogramming in homeostasis and disease. Biomolecules 10(9):1211. https://doi.org/10.3390/biom10091211PMID: 32825327; PMCID: PMC7563541

Article  CAS  PubMed  PubMed Central  Google Scholar 

Mohammadi S, Rastmanesh R, Jahangir F, Amiri Z, Djafarian K, Mohsenpour MA, Hassanipour S, Ghaffarian-Bahraman A (2021) Melatonin supplementation and anthropometric indices: A randomized Double-Blind controlled clinical trial. Biomed Res Int 2021:3502325. https://doi.org/10.1155/2021/3502325PMID: 34423033; PMCID: PMC8373505

Article  CAS  PubMed  PubMed Central  Google Scholar 

Pivonello C, Negri M, Patalano R, Amatrudo F, Montò T, Liccardi A, Graziadio C, Muscogiuri G, Pivonello R, Colao A (2022) The role of melatonin in the molecular mechanisms underlying metaflammation and infections in obesity: A narrative review. Obes Rev 23(3):e13390. https://doi.org/10.1111/obr.13390Epub 2021 Dec 3. PMID: 34861097; PMCID: PMC9285339

Article  CAS  PubMed  Google Scholar 

Szewczyk-Golec K, Rajewski P, Gackowski M et al (2017) Melatonin supplementation lowers oxidative stress and regulates adipokines in obese patients on a Calorie-Restricted diet. Oxid Med Cell Longev 2017:8494107. https://doi.org/10.1155/2017/8494107

Article  CAS  PubMed  PubMed Central  Google Scholar 

Marqueze EC, Nogueira LFR, Vetter C, Skene DJ, Cipolla-Neto J, Moreno CRC (2021) Exogenous melatonin decreases circadian misalignment and body weight among early types. J Pineal Res 71(2):e12750. https://doi.org/10.1111/jpi.12750

Article  CAS  PubMed  Google Scholar 

Nogueira LFR, Marqueze EC (2021) Effects of melatonin supplementation on eating habits and appetite-regulating hormones: a systematic review of randomized controlled clinical and preclinical trials. Chronobiol Int 38(8):1089–1102 Epub 2021 May 2. PMID: 33934676

Article  CAS  PubMed  Google Scholar 

Nogueira LFR, Crispim CA, Cipolla-Neto J, de Castro Moreno CR, Marqueze EC (2022) The effect of exogenous melatonin on eating habits of female night workers with excessive weight. Nutrients 14(16):3420. https://doi.org/10.3390/nu14163420PMID: 36014925; PMCID: PMC9412377

Article  CAS  PubMed  PubMed Central  Google Scholar 

Fatemeh G, Sajjad M, Niloufar R, Neda S, Leila S, Khadijeh M (2022) Effect of melatonin supplementation on sleep quality: a systematic review and meta-analysis of randomized controlled trials. J Neurol 269(1):205–216. https://doi.org/10.1007/s00415-020-10381-wEpub 2021 Jan 8. PMID: 33417003

Article  CAS  PubMed  Google Scholar 

Azzeh FS, Kamfar WW, Ghaith MM, Alsafi RT, Shamlan G, Ghabashi MA, Farrash WF, Alyamani RA, Alazzeh AY, Alkholy SO, Bakr EH, Qadhi AH, Arbaeen AF (2024) Unlocking the health benefits of melatonin supplementation: A promising preventative and therapeutic strategy. Med (Baltim) 103(38):e39657. https://doi.org/10.1097/MD.0000000000039657PMID: 39312371; PMCID: PMC11419438

Article  CAS  Google Scholar 

Bonomini F, Borsani E, Favero G, Rodella LF, Rezzani R (2018) Dietary melatonin supplementation could be a promising preventing/therapeutic approach for a variety of liver diseases. Nutrients 10(9):1135. https://doi.org/10.3390/nu10091135PMID: 30134592; PMCID: PMC6164189

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ziaei S, Hasani M, Malekahmadi M, Daneshzad E, Kadkhodazadeh K, Heshmati J (2024) Effect of melatonin supplementation on cardiometabolic risk factors, oxidative stress and hormonal profile in PCOS patients: a systematic review and meta-analysis of randomized clinical trials. J Ovarian Res 17(1):138. https://doi.org/10.1186/s13048-024-01450-zPMID: 38965577; PMCID: PMC11225253

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ramos Gonzalez M, Axler MR, Kaseman KE, Lobene AJ, Farquhar WB, Witman MA, Kirkman DL, Lennon SL (2023) Melatonin supplementation reduces nighttime blood pressure but does not affect blood pressure reactivity in normotensive adults on a high-sodium diet. Am J Physiol Regul Integr Comp Physiol 325(5):R465–R473. https://doi.org/10.1152/ajpregu.00101.2023Epub 2023 Aug 29. PMID: 37642281; PMCID: PMC11178293

Article  CAS  PubMed  PubMed Central  Google Scholar 

Martorina W, Tavares A (2023) Glycemic variability in patients with type 2 diabetes mellitus (T2DM): the role of melatonin in a crossover, Double-Blind, Placebo-Controlled, randomized study. Nutrients 15(16):3523 Published 2023 Aug 10. https://doi.org/10.3390/nu15163523

Article  PubMed  PubMed Central  Google Scholar 

Bazyar H, Zare Javid A, Bavi Behbahani H, Moradi F, Moradi Poode B, Amiri P (2021) Consumption of melatonin supplement improves cardiovascular disease risk factors and anthropometric indices in type 2 diabetes mellitus patients: a double-blind, randomized, placebo-controlled trial. Trials 22(1):231. https://doi.org/10.1186/s13063-021-05174-z. Published 2021 Mar 25

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ramos Gonzalez M, Axler MR, Kaseman KE et al (2023) Melatonin supplementation does not alter vascular function or oxidative stress in healthy normotensive adults on a high sodium diet. Physiol Rep 11(24):e15896. https://doi.org/10.14814/phy2.15896

Article  CAS  PubMed  PubMed Central  Google Scholar 

Franco C, Sciatti E, Favero G, Bonomini F, Vizzardi E, Rezzani R (2022) Essential hypertension and oxidative stress: novel future perspectives. Int J Mol Sci 23(22):14489 Published 2022 Nov 21. https://doi.org/10.3390/ijms232214489

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ostadmohammadi V, Soleimani A, Bahmani F et al (2020) The effects of melatonin supplementation on parameters of mental health, glycemic control, markers of cardiometabolic risk, and oxidative stress in diabetic Hemodialysis patients: A randomized, Double-Blind, Placebo-Controlled trial. J Ren Nutr 30(3):242–250. https://doi.org/10.1053/j.jrn.2019.08.003

Article  CAS  PubMed  Google Scholar 

Pahlavani N, Malekahmadi M, Sedaghat A, Rostami A, Alkadir OKA, Taifi A, Ranjbar G, Sahebkar A, Abdelbasset WK, Beigmohammadi MT, Mir M, Bagheri Moghaddam A, Tabesh H, Sadeghi O, Gholizadeh Navashenaq J, Firouzi S, Fathi Najafi M, Safarian M, Ghayour-Mobarhan M (2022) Effects of melatonin and Propolis supplementation on inflammation, oxidative stress, and clinical outcomes in patients with primary Pneumosepsis: A randomized controlled clinical trial. Complement Med Res 29(4):275–285 English. doi: 10.1159/000523766. Epub 2022 Feb 25. PMID: 35220312

Article  PubMed  Google Scholar 

Wang X, Wang Z, Cao J, Dong Y, Chen Y (2023) Gut microbiota-derived metabolites mediate the neuroprotective effect of melatonin in cognitive impairment induced by sleep deprivation. Microbiome 11(1):17. https://doi.org/10.1186/s40168-022-01452-3PMID: 36721179; PMCID: PMC9887785

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li W, Wang Z, Cao J, Dong Y, Chen Y (2023) Melatonin improves skin barrier damage caused by sleep restriction through gut microbiota. J Pineal Res 75(1):e12874. https://doi.org/10.1111/jpi.12874Epub 2023 Apr 24. PMID: 37057339

Article  CAS  PubMed  Google Scholar 

Li F, Lai J, Ma F, Cai Y, Li S, Feng Z, Lu Z, Liu X, Ke Q, Hao H, Xiao X (2023) Maternal melatonin supplementation shapes gut microbiota and protects against inflammation in early life. Int Immunopharmacol 120:110359 Epub 2023 May 29. PMID: 37257272

Article  CAS  PubMed  Google Scholar 

Zhang Y, Lang R, Guo S et al (2022) Intestinal microbiota and melatonin in the treatment of secondary injury and complications after spinal cord injury. Front Neurosci 16:981772 Published 2022 Nov 9. https://doi.org/10.3389/fnins.2022.981772

Article  PubMed  PubMed Central  Google Scholar 

Megerian MF, Kim JS, Badreddine J, Hong SH, Ponsky LE, Shin JI, Ghayda RA (2023) Melatonin and prostate cancer: Anti-tumor roles and therapeutic application. Aging Dis 14(3):840–857 PMID: 37191417; PMCID: PMC10187692

Article  PubMed  PubMed Central  Google Scholar 

Mutlu EG, Baltaci SB (2020) Zinc and melatonin supplementation ameliorates brain cortex tissue damage in DMBA-induced breast cancer in rats. Bratisl Lek Listy.;121(10):749–752. https://doi.org/10.4149/BLL_2020_122. PMID: 32955908

Tamtaji OR, Mirhosseini N, Reiter RJ, Behnamfar M, Asemi Z (2019) Melatonin and pancreatic cancer: current knowledge and future perspectives. J Cell Physiol 234(5):5372–5378. https://doi.org/10.1002/jcp.27372Epub 2018 Sep 19. PMID: 30229898

Article  CAS  PubMed  Google Scholar 

Mukhopadhyay ND, Khorasanchi A, Pandey S, Nemani S, Parker G, Deng X, Arthur DW, Urdaneta A, Del Fabbro E (2024) Melatonin supplementation for Cancer-Related fatigue in patients with early stage breast Cancer receiving radiotherapy: A Double-Blind Placebo-Controlled trial. Oncologist 29(2):e206–e212. https://doi.org/10.1093/oncolo/oyad250PMID: 37699115; PMCID: PMC10836305

Article