Maccio U, Zinkernagel AS, Shambat SM, Zeng X, Varga Z. SARS-CoV-2 leads to a small vessel endotheliitis in the heart. EBioMedicine. 2021;63(8):103182.
Article CAS PubMed PubMed Central Google Scholar
Song ER, Zhang C, Israelow B, Lu-Culligan A, Prado AV, Skriabine S, Lu PW, Weizman O-E, Liu FM, Dai YL, et al. Neuroinvasion of SARS-CoV-2 in human and mouse brain. J Exp Med. 2021;218(3): e20202135.
Article CAS PubMed PubMed Central Google Scholar
Saeed U, Piracha ZZ, Uppal SR, Waheed Y, Uppal R. SARS-CoV-2 induced hepatic injuries and liver complications. Front Cell Infect Mi. 2022;12:726263.
Leftwich HK, Vargas-Robles D, Rojas-Correa M, Yap YR, Bhattarai S, Ward DV, Fujimori G, Forconi CS, Yeboah T, Carter A, et al. The microbiota of pregnant women with SARS-CoV-2 and their infants. Microbiome. 2023;11(1):141.
Article CAS PubMed PubMed Central Google Scholar
Montano M, Victor AR, Griffin DK, Duong T, Bolduc N, Farmer A, Garg V, Hadjantonakis AK, Coates A, Barnes FL, et al. SARS-CoV-2 can infect human embryos. Sci Rep. 2022;12(1):15451.
Article CAS PubMed PubMed Central Google Scholar
Wu H, Liao S, Wang Y, Guo M, Lin X, Wu J, Wang R, Lv D, Wu D, He M, et al. Molecular evidence suggesting the persistence of residual SARS-CoV-2 and immune responses in the placentas of pregnant patients recovered from COVID-19. Cell Prolif. 2021;54(9): e13091.
Article CAS PubMed PubMed Central Google Scholar
Vivanti AJ, Vauloup-Fellous C, Prevot S, Zupan V, Suffee C, Do Cao J, Benachi A, De Luca D. Transplacental transmission of SARS-CoV-2 infection. Nat Commun. 2020;11(1):3572.
Article CAS PubMed PubMed Central Google Scholar
Young BK, Ramakrishnan C, Ganjawala T, Wang P, Deisseroth K, Tian N. An uncommon neuronal class conveys visual signals from rods and cones to retinal ganglion cells. P Natl Acad Sci USA. 2021;118(44): e2104884118.
Casagrande M, Fitzek A, Püschel K, Aleshcheva G, Schultheiss HP, Berneking L, Spitzer MS, Schultheiss M. Detection of SARS-CoV-2 in human retinal biopsies of deceased COVID-19 patients. Ocul Immunol Inflamm. 2020;28(5):721–5.
Article CAS PubMed Google Scholar
Abdolrahimzadeh S, Lodesani M, Rullo D, Mariani A, Scuderi G. Overview of the retina and imaging in patients with severe acute respiratory syndrome coronavirus 2. Int Ophthalmol. 2022;42(11):3601–10.
Article PubMed PubMed Central Google Scholar
Haseeb AA, Solyman O, Abushanab MM, Obaia ASA, Elhusseiny AM. Ocular complications following vaccination for COVID-19: a one-year retrospective. Vaccines. 2022;10(2):342.
Article CAS PubMed PubMed Central Google Scholar
Jeong GU, Kwon HJ, Ng WH, Liu X, Moon HW, Yoon GY, Shin HJ, Lee IC, Ling ZL, Spiteri AG, et al. Ocular tropism of SARS-CoV-2 in animal models with retinal inflammation via neuronal invasion following intranasal inoculation. Nat Commun. 2022;13(1):7576.
Schaub JM, Chou CW, Kuo HC, Javanmardi K, Hsieh CL, Goldsmith J, DiVenere AM, Le KC, Wrapp D, Byrne PO, et al. Expression and characterization of SARS-CoV-2 spike proteins. Nat Protoc. 2021;16(11):5339–56.
Article CAS PubMed PubMed Central Google Scholar
Wang QH, Zhang YF, Wu LL, Niu S, Song CL, Zhang ZY, Lu GW, Qiao CP, Hu Y, Yuen KY, et al. Structural and functional basis of SARS-CoV-2 entry by using human ACE2. Cell. 2020;181(4):894–904.
Article CAS PubMed PubMed Central Google Scholar
Hoffmann M, Kleine-Weber H, Schroeder S, Krüger N, Herrler T, Erichsen S, Schiergens TS, Herrler G, Wu N-H, Nitsche A, et al. SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor. Cell. 2020;181(2):271–80.
Article CAS PubMed PubMed Central Google Scholar
Zhou Y, Wang M, Li Y, Wang P, Zhao P, Yang Z, Wang S, Zhang L, Li Z, Jia K, et al. SARS-CoV-2 Spike protein enhances ACE2 expression via facilitating Interferon effects in bronchial epithelium. Immunol Lett. 2021;237:33–41.
Article CAS PubMed PubMed Central Google Scholar
Kiseleva AA, Troisi EM, Hensley SE, Kohli RM, Epstein JA. SARS-CoV-2 spike protein binding selectively accelerates substrate-specific catalytic activity of ACE2. J Biochem. 2021;170(2):299–306.
Article CAS PubMed PubMed Central Google Scholar
Kim ES, Jeon MT, Kim KS, Lee S, Kim S, Kim DG. Spike proteins of SARS-CoV-2 induce pathological changes in molecular delivery and metabolic function in the brain endothelial cells. Viruses. 2021;13(10):2021.
Article CAS PubMed PubMed Central Google Scholar
Cappelletti G, Brambilla L, Melzi V, Rizzuti M, Nizzardo M, Trabattoni D, Corti S, Clerici M, Biasin M. SARS-CoV-2 infection and Spike protein exposure alter iPSC-derived human brain organoid homeostasis. J Immunol. 2023;210(1_Supplement):236.
Khaddaj-Mallat R, Aldib N, Bernard M, Paquette AS, Ferreira A, Lecordier S, Saghatelyan A, Flamand L, ElAli A. SARS-CoV-2 deregulates the vascular and immune functions of brain pericytes via Spike protein. Neurobiol Dis. 2021;161:105561.
Article CAS PubMed PubMed Central Google Scholar
Jiang ZX, Zhang H, Gao J, Yu H, Han RF, Zhu L, Chen X, Fan Q, Hao P, Wang LM, et al. ACE2 expression is upregulated in inflammatory corneal epithelial cells and attenuated by resveratrol. Invest Ophth Vis Sci. 2021;62(7):25.
Collin J, Queen R, Zerti D, Dorgau B, Georgiou M, Djidrovski I, Hussain R, Coxhead JM, Joseph A, Rooney P, et al. Co-expression of SARS-CoV-2 entry genes in the superficial adult human conjunctival, limbal and corneal epithelium suggests an additional route of entry via the ocular surface. Ocul Surf. 2021;19:190–200.
Article PubMed PubMed Central Google Scholar
Eriksen AZ, Moller R, Makovoz B, Uhl SA, tenOever BR, Blenkinsop TA. SARS-CoV-2 infects human adult donor eyes and hESC-derived ocular epithelium. Cell Stem Cell. 2021;28(7):1205–20.
Article CAS PubMed PubMed Central Google Scholar
Li YP, Ma Y, Wang N, Jin ZB. Eyes on coronavirus. Stem Cell Res. 2021;51:102200.
Article CAS PubMed PubMed Central Google Scholar
Schnichels S, Rohrbach JM, Bayyoud T, Thaler S, Ziemssen F, Hurst J. Can SARS-CoV-2 infect the eye?-An overview of the receptor status in ocular tissue. Ophthalmologe. 2020;117(7):618–21.
Article CAS PubMed PubMed Central Google Scholar
Cora V, Haderspeck J, Antkowiak L, Mattheus U, Neckel PH, Mack AF, Bolz S, Ueffing M, Pashkovskaia N, Achberger K, et al. A cleared view on retinal organoids. Cells. 2019;8(5):391.
Article CAS PubMed PubMed Central Google Scholar
Pei R, Feng J, Zhang Y, Sun H, Li L, Yang X, He J, Xiao S, Xiong J, Lin Y, et al. Host metabolism dysregulation and cell tropism identification in human airway and alveolar organoids upon SARS-CoV-2 infection. Protein Cell. 2021;12(9):717–33.
Article CAS PubMed Google Scholar
Salahudeen AA, Choi SS, Rustagi A, Zhu J, van Unen V, de la Sean O, Flynn RA, Margalef-Català M, Santos AJM, Ju J, et al. Progenitor identification and SARS-CoV-2 infection in human distal lung organoids. Nature. 2020;588(7839):670–5.
Comments (0)