Female-specific risk factors for cardiovascular disease: an update

World Health Organization Cardiovascular diseases (CVDs) Fact sheet. https://www.who.int/en/news-room/fact-sheets/detail/cardiovascular-diseases-(cvds)

Meyer MR, Haas E, Barton M (2006) Gender differences of cardiovascular disease: new perspectives for estrogen receptor signaling. Hypertension 47(6):1019–1026. https://doi.org/10.1161/01.HYP.0000223064.62762.0b

Article  CAS  PubMed  Google Scholar 

Gao Z, Chen Z, Sun A, Deng X (2019) Gender differences in cardiovascular disease. Med Novel Technol Devices 100025. 410.1016/j.medntd.2019.100025

Iorga A, Cunningham CM, Moazeni S, Ruffenach G, Umar S, Eghbali M (2017) The protective role of estrogen and estrogen receptors in cardiovascular disease and the controversial use of estrogen therapy. Biol Sex Differ 8(1):33. https://doi.org/10.1186/s13293-017-0152-8

Article  CAS  PubMed  PubMed Central  Google Scholar 

Garaulet M, Pérez-Llamas F, Baraza JC, Garcia-Prieto MD, Fardy PS, Tébar FJ, Zamora S (2002) Body fat distribution in pre-and post-menopausal women: metabolic and anthropometric variables. J Nutr Health Aging 6(2):123–126

CAS  PubMed  Google Scholar 

Yazdanyar A, Newman AB (2009) The burden of cardiovascular disease in the elderly: morbidity, mortality, and costs. Clin Geriatr Med.;25(4):563– 77, vii. https://doi.org/10.1016/j.cger.2009.07.007

Appelman Y, van Rijn BB, Ten Haaf ME, Boersma E, Peters SA (2015) Sex differences in cardiovascular risk factors and disease prevention. Atherosclerosis 241(1):211–218. https://doi.org/10.1016/j.atherosclerosis.2015.01.027

Article  CAS  PubMed  Google Scholar 

Coulam C, Anderson S, Annegers J (1986) Incidence of premature ovarian failure. Obstet Gynecol 67:604–606

CAS  PubMed  Google Scholar 

Guan C, Zahid S, Minhas AS, Ouyang P, Vaught A, Baker V, Michos ED (2022) Polycystic ovary syndrome: a risk-enhancing factor for cardiovascular disease. Fertil Steril 117:924–35924. https://doi.org/10.1016/j.fertnstert.2022.03.009

Article  CAS  PubMed  Google Scholar 

Wang G, Buckley JP, Bartell TR, Hong X, Pearson C, Wang X (2023) Gestational diabetes Mellitus, Postpartum Lipidomic signatures, and subsequent risk of type 2 diabetes: a lipidome-wide Association study. Diabetes Care 46(6):1223–1230. https://doi.org/10.2337/dc22-1841

Article  CAS  PubMed  PubMed Central  Google Scholar 

Vryonidou A, Paschou SA, Muscogiuri G, Orio F, Goulis DG MECHANISMS IN ENDOCRINOLOGY: metabolic syndrome through the female life cycle. Eur J Endocrinol 2015 173 R153–R163. (https://doi.org/10.1530/EJE-15-0275)

Maggio M, Ceda GP, Lauretani F, Bandinelli S, Corsi AM, Giallauria F, Guralnik JM, Zuliani G, Cattabiani C, Parrino S et al (2011) SHBG, sex hormones, and inflammatory markers in older women. J Clin Endocrinol Metab 96:1053–1059. https://doi.org/10.1210/jc.2010-1902)

Article  CAS  PubMed  PubMed Central  Google Scholar 

Goossens GH, Jocken J, Blaak E (2021) Sexual dimorphism in cardiometabolic health: the role of adipose tissue, muscle and liver. Nat Reviews Endocrinol 17:47–66

Article  Google Scholar 

Cignarella A, Kratz M, Bolego C (2010) Emerging role of estrogen in the control of cardiometabolic disease. Trends Pharmacol Sci 31:183–189

Article  CAS  PubMed  Google Scholar 

Trenti A, Tedesco S, Boscaro C, Trevisi L, Bolego C, Cignarella A (2018) Estrogen, angiogenesis, immunity and cell metabolism: solving the puzzle. Int J Mol Sci 19:859

Article  PubMed  PubMed Central  Google Scholar 

Maclaran K (2015) N. Panay. Current concepts in premature ovarian insufficiency. Women’s Health 169–182

Lambrinoudaki I, Paschou SA, Lumsden MA, Faubion S, Makrakis E, Kalantaridou S, Panay N Premature ovarian insufficiency: a toolkit for the primary care physician. Maturitas 2021 147:53–63

Ishizuka B Current understanding of the etiology, Symptomatology, and Treatment options in premature ovarian insufficiency (POI). Front Endocrinol 12:626924

Rossetti R, Ferrari I, Bonomi M, Persani L (2017) Genetics of primary ovarian insufficiency. Clin Genet. 183–198

Anagnostis P, Christou K, Artzouchaltzi AM, Gkekas N, Kosmidou N, Siolos P et al (2019) Early menopause and premature ovarian insufficiency are associated with increased risk of type 2 diabetes: a systematic review and meta-analysis. Eur J Endocrinol 180:41–50

Article  CAS  PubMed  Google Scholar 

Liu J, Jin X, Liu W, Chen W, Wang L, Feng Z, Huang J The risk of long-term cardiometabolic disease in women with premature or early menopause: a systematic review and meta-analysis front. Cardiovasc Med 10:1131251

Nadal A, Alonso-Magdalena P, Soriano S, Quesada I, Ropero AB (2009) The pancreatic beta-cell as a target of estrogens and xenoestrogens: implications for blood glucose homeostasis and diabetes. Mol Cell Endocrinol 304:63–68

Article  CAS  PubMed  Google Scholar 

Paschou SA, Anagnostis P, Pavlou DI, Vryonidou A, Goulis DG (2018) Lambrinoudaki I. Diabetes in menopause: risks and management. Current Vascular Pharmacology

Honigberg MC, Zekavat SM, Aragam K, Klarin D, Bhatt DL, Scott NS et al (2019) Long-Term Cardiovascular risk in women with hypertension during pregnancy. J Am Coll Cardiol 74(22):2743–2754. https://doi.org/10.1016/j.jacc.2019.09.052

Article  PubMed  PubMed Central  Google Scholar 

Ossewaarde ME, Bots ML, Verbeek ALM, Peeters PHM, van der Graaf Y, Grobbee DE et al (2005) Age at Menopause, cause-Specific Mortality and Total Life Expectancy. Epidemiology 16(4):556–562

Article  PubMed  Google Scholar 

van Roeters JE, Heida KY, Bots ML, Hoek A (2016) Cardiovascular disease risk in women with premature ovarian insufficiency: a systematic review and meta-analysis. J Prev Cardiol 23(2):178–186

Article  Google Scholar 

Zhu D, Chung HF, Dobson AJ, Pandeya N, Giles GG, Bruinsma F et al Age at natural menopause and risk of incident cardiovascular disease: a pooled analysis of individual patient data. Lancet Public Health 2019 4(11):e553–e564. https://doi.org/10.1016/S2468-2667(19)30155-0

Ley SH, Li Y, Tobias DK, Manson JE, Rosner B, Hu FB, Rexrode KM (2017) Duration of Reproductive Life Span, Age at Menarche, and age at Menopause are Associated with Risk of Cardiovascular Disease in Women. J Am Heart Assoc 6(11):e006713. https://doi.org/10.1161/JAHA.117.006713

Article  PubMed  PubMed Central  Google Scholar 

Tao X-Y, Zuo A-Z, Wang J-Q, Tao F-B (2016) Effect of primary ovarian insufficiency and early natural menopause on mortality: a meta-analysis. Climacteric 19(1):27–36. https://doi.org/10.3109/13697137.2015.1094784

Article  PubMed  Google Scholar 

Muka T, Oliver-Williams C, Kunutsor S, Laven JS, Fauser BC, Chowdhury R et al (2016) Association of Age at Onset of Menopause and Time since Onset of Menopause with Cardiovascular outcomes, Intermediate Vascular traits, and all-cause mortality: a systematic review and Meta-analysis. JAMA Cardiol 1(7):767–776. https://doi.org/10.1001/jamacardio.2016.2415

Article  PubMed  Google Scholar 

Kok HS, van Asselt KM, van der Schouw YT, van der Tweel I, Peeters PH, Wilson PW et al (2006) Heart disease risk determines menopausal age rather than the reverse. J Am Coll Cardiol 47(10):1976–1983. https://doi.org/10.1016/j.jacc.2005.12.066

Article  PubMed  Google Scholar 

Kalantaridou SN, Naka KK, Papanikolaou E, Kazakos N, Kravariti M, Calis KA et al (2004) Impaired endothelial function in young women with premature ovarian failure: normalization with hormone therapy. J Clin Endocrinol Metab 89:3907–3913. https://doi.org/10.1210/jc.2004-0015

Article  CAS  PubMed  Google Scholar 

Stuenkel CA (2012) Cardiovascular risk and early menopause: cause or consequence? Menopause 19:1067–1069

Article  PubMed  Google Scholar 

Stuenkel CA, Davis SR, Gompel A, Lumsden MA, Murad MH, Pinkerton JV, Santen RJ (2015) Treatment of symptoms of the menopause: an endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab 100:3975–4011. https://doi.org/10.1210/jc.2015-2236

Article  CAS  PubMed  Google Scholar 

Faubion S.S., Sood R, Kapoor E (2017) Genitourinary syndrome of menopause: management strategies for the clinician. Mayo Clin Proc 92:1842–1849

Bozdag G, Mumusoglu S, Zengin D, Karabulut E, Yildiz BO (2016) The prevalence and phenotypic features of polycystic ovary syndrome: a systematic review and meta-analysis. Hum Reprod 31(12):2841–2855. https://doi.org/10.1093/humrep/dew218

Article  PubMed  Google Scholar 

Rotterdam ESHRE, ASRM-Sponsored PCOS Consensus Work-shop Group (2003) Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome. Fertil Steril 81(1):19–25

Google Scholar 

Zawadski JK (1992) Diagnostic criteria for polycystic ovary syndrome: towards a rational approach. In: Dunaif A (ed) Polycystic ovary syndrome. Blackwell Scientific, Boston, pp 377–384

Google Scholar 

Azziz R, Carmina E, Dewailly D, Diamanti-Kandarakis E, Escobar-Morreale HF, Futterweit W, Janssen OE, Legro RS, Norman RJ, Taylor AE et al (2009) The androgen excess and PCOS Society criteria for the polycystic ovary syndrome: the complete task force report. Fertil Steril 91:456–488

Article  PubMed  Google Scholar 

Kosova G, Urbanek M (2013) Genetics of the polycystic ovary syndrome. Mol Cell Endocrinol 373:29–38. https://doi.org/10.1016/j.mce.2012.10.009

Article  CAS  PubMed  Google Scholar 

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