Sodium Houttuyfonate Ameliorates DSS-induced Colitis Aggravated by Candida albicans through Dectin-1/NF-κB/miR-32-5p/NFKBIZ Axis Based on Intestinal microRNA Profiling

Shingnaisui, K., et al. 2018. Therapeutic potentials of Houttuynia cordata Thunb. against inflammation and oxidative stress: A review. Journal of Ethnopharmacology 220: 35–43.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wu, Y., et al. 2022. Research progress on chemical components, pharmacology and quality control of Houttuyniae Herba. Chinese Journal of Pharmaceutical Analysis 42 (01): 108–120.

Google Scholar 

Satthakarn, S., et al. 2015. Vaginal innate immune mediators are modulated by a water extract of Houttuynia cordata Thunb. BMC Complementary and Alternative Medicine 15: 183.

Article  PubMed  PubMed Central  Google Scholar 

Zhang, L., et al. 2020. Sodium houttuyfonate enhances the intestinal barrier and attenuates inflammation induced by Salmonella typhimurium through the NF-κB pathway in mice. International Immunopharmacology 89 (Pt A): 107058.

Article  CAS  PubMed  Google Scholar 

Zhu, H., et al. 2018. Houttuynia cordata polysaccharides ameliorate pneumonia severity and intestinal injury in mice with influenza virus infection. Journal of Ethnopharmacology 218: 90–99.

Article  CAS  PubMed  Google Scholar 

Chen, J., et al. 2014. A comparative study of sodium houttuyfonate and 2-undecanone for their in vitro and in vivo anti-inflammatory activities and stabilities. International Journal of Molecular Sciences 15 (12): 22978–22994.

Article  CAS  PubMed  PubMed Central  Google Scholar 

White, P.L., et al. 2021. A National Strategy to Diagnose Coronavirus Disease 2019-Associated Invasive Fungal Disease in the Intensive Care Unit. Clinical Infectious Diseases 73 (7): e1634–e1644.

Article  CAS  PubMed  Google Scholar 

Gajendran, M., et al. 2019. A comprehensive review and update on ulcerative colitis. Disease-a-month 65 (12): 100851.

Article  PubMed  Google Scholar 

da Silva, B.C., et al. 2014. Epidemiology, demographic characteristics and prognostic predictors of ulcerative colitis. World Journal of Gastroenterology 20 (28): 9458–9467.

Article  PubMed  PubMed Central  Google Scholar 

Li, X.V., et al. 2022. Immune regulation by fungal strain diversity in inflammatory bowel disease. Nature 603 (7902): 672–678.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ost, K.S., et al. 2021. Adaptive immunity induces mutualism between commensal eukaryotes. Nature 596 (7870): 114–118.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li, X.Y., et al. 2014. MiR-204/miR-211 downregulation contributes to candidemia-induced kidney injuries via derepression of Hmx1 expression. Life Sciences 102 (2): 139–144.

Article  CAS  PubMed  Google Scholar 

Halder, L.D., et al. 2022. Candida albicans induces cross-kingdom mirna trafficking in human monocytes to promote fungal growth. mBio 13 (1): e0356321.

Article  Google Scholar 

Ni, L., et al. 2022. The immune change of the lung and bowel in an ulcerative colitis rat model and the protective effect of sodium houttuyfonate combined with matrine. Frontiers in Immunology 13: 888918.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wang, J., et al. 2022. The traditional chinese medicine houttuynia cordata thunb decoction alters intestinal barrier function via an EGFR dependent MAPK (ERK1/2) signalling pathway. Phytomedicine 105: 154353.

Article  CAS  PubMed  Google Scholar 

J.H. Wang, et al. 2017. Houttuynia cordata facilitates metformin on ameliorating insulin resistance associated with gut microbiota alteration in OLETF Rats, genes (Basel) 8(10). https://doi.org/10.3390/genes8100239.

Zheng, Y., et al. 2019. Reshaping fecal gut microbiota composition by growing with Polygonum cuspidatum Houttuynia cordata, and Ipomoea aquatica. Canadian Journal of Microbiology 65 (7): 522–529.

Article  CAS  PubMed  Google Scholar 

Ma, K., et al. 2021. Sodium houttuyfonate attenuates dextran sulfate sodium associated colitis precolonized with Candida albicans through inducing β-glucan exposure. Journal of Leukocyte Biology 110 (5): 927–937.

Article  CAS  PubMed  Google Scholar 

Shao, J., et al. 2017. Synergistic in vitro activity of sodium houttuyfonate with fluconazole against clinical Candida albicans strains under planktonic growing conditions. Pharmaceutical Biology 55 (1): 355–359.

Article  CAS  PubMed  Google Scholar 

Cheng, T., et al. 2023. Sodium houttuyfonate derived from Houttuynia cordata Thunb improves intestinal malfunction via maintaining gut microflora stability in Candida albicans overgrowth aggravated ulcerative colitis. Food & Function 14 (2): 1072–1086.

Article  CAS  Google Scholar 

Li, M., et al. 2018. A circular transcript of NCX1 gene mediates ischemic myocardial injury by targeting miR-133a-3p. Theranostics 8 (21): 5855–5869.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gheytanchi, E., et al. 2021. Morphological and molecular characteristics of spheroid formation in HT-29 and Caco-2 colorectal cancer cell lines. Cancer Cell International 21 (1): 204.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Nanki, K., et al. 2020. Somatic inflammatory gene mutations in human ulcerative colitis epithelium. Nature 577 (7789): 254–259.

Article  CAS  PubMed  Google Scholar 

Kakiuchi, N., et al. 2020. Frequent mutations that converge on the NFKBIZ pathway in ulcerative colitis. Nature 577 (7789): 260–265.

Article  CAS  PubMed  Google Scholar 

Quintin, J., et al. 2012. Candida albicans infection affords protection against reinfection via functional reprogramming of monocytes. Cell Host & Microbe 12 (2): 223–232.

Article  CAS  Google Scholar 

Hao, J., et al. 2017. MicroRNA-375 is induced in cisplatin nephrotoxicity to repress hepatocyte nuclear factor 1-β. Journal of Biological Chemistry 292 (11): 4571–4582.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sonoyama, K., et al. 2011. Gut colonization by Candida albicans aggravates inflammation in the gut and extra-gut tissues in mice. Medical Mycology 49 (3): 237–247.

Article  CAS  PubMed  Google Scholar 

Alamdari-Palangi, V., et al. 2021. microRNA in inflammatory bowel disease at a glance. European Journal of Gastroenterology and Hepatology 32 (2): 140–148.

Article  PubMed  Google Scholar 

Ghafouri-Fard, S., et al. 2020. The crucial role of non-coding RNAs in the pathophysiology of inflammatory bowel disease. Biomedicine & Pharmacotherapy 129: 110507.

Article  CAS  Google Scholar 

Masi, L., et al. 2022. MicroRNAs as innovative biomarkers for inflammatory bowel disease and prediction of colorectal cancer. International Journal of Molecular Sciences 23 (14): 7991.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Nijakowski, K., and A. Surdacka. 2020. Salivary biomarkers for diagnosis of inflammatory bowel diseases: A systematic review. International Journal of Molecular Sciences 21 (20): 7477.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Agustinho, D.P., et al. 2017. Dectin-1 is required for miR155 upregulation in murine macrophages in response to Candida albicans. Virulence 8 (1): 41–52.

Article  CAS 

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