Rieder, F., C. Fiocchi, and G. Rogler. 2017. Mechanisms, management, and treatment of fibrosis in patients with inflammatory bowel diseases. Gastroenterology 152: 340–350.e346.
Lawrance, I.C., G. Rogler, G. Bamias, et al. 2017. Cellular and molecular mediators of intestinal fibrosis. Journal of Crohn’s & Colitis 11: 1491–1503.
Flier, S.N., H. Tanjore, E.G. Kokkotou, et al. 2010. Identification of epithelial to mesenchymal transition as a novel source of fibroblasts in intestinal fibrosis. Journal of Biological Chemistry 285: 20202–20212.
Article CAS PubMed PubMed Central Google Scholar
Rieder, F., S.P. Kessler, G.A. West, et al. 2011. Inflammation-induced endothelial-to-mesenchymal transition: A novel mechanism of intestinal fibrosis. American Journal of Pathology 179: 2660–2673.
Article CAS PubMed PubMed Central Google Scholar
Brittan, M., V. Chance, G. Elia, et al. 2005. A regenerative role for bone marrow following experimental colitis: Contribution to neovasculogenesis and myofibroblasts. Gastroenterology 128: 1984–1995.
Little, K., M. Llorián-Salvador, M. Tang, et al. 2020. Macrophage to myofibroblast transition contributes to subretinal fibrosis secondary to neovascular age-related macular degeneration. Journal of Neuroinflammation 17: 355.
Article CAS PubMed PubMed Central Google Scholar
Haider, N., L. Boscá, H.R. Zandbergen, et al. 2019. Transition of macrophages to fibroblast-like cells in healing myocardial infarction. Journal of the American College of Cardiology 74: 3124–3135.
Article CAS PubMed PubMed Central Google Scholar
Wang, Y.Y., H. Jiang, J. Pan, et al. 2017. Macrophage-to-myofibroblast transition contributes to interstitial fibrosis in chronic renal allograft injury. Journal of the American Society of Nephrology 28: 2053–2067.
Article CAS PubMed PubMed Central Google Scholar
Tao, L., W. Ma, L. Wu, et al. 2019. Glial cell line-derived neurotrophic factor (GDNF) mediates hepatic stellate cell activation via ALK5/Smad signalling. Gut 68: 2214–2227.
Article CAS PubMed Google Scholar
Zeng, J., H. Yu, and H.T. Gan. 2021. Glial cell line-derived neurotrophic factor ameliorates dextran sulfate sodium-induced colitis in mice via a macrophage-mediated pathway. International Immunopharmacology 100: 108143.
Article CAS PubMed Google Scholar
Hine, A.M., and P. Loke. 2019. Intestinal macrophages in resolving inflammation. The Journal of Immunology 203: 593–599.
Article CAS PubMed Google Scholar
Liu, B., J. Jiang, H. Liang, et al. 2021. Natural killer T cell/IL-4 signaling promotes bone marrow-derived fibroblast activation and M2 macrophage-to-myofibroblast transition in renal fibrosis. International Immunopharmacology 98: 107907.
Article CAS PubMed Google Scholar
Tang, P.C., J.Y. Chung, V.W. Xue, et al. 2022. Smad3 promotes cancer-associated fibroblasts generation via macrophage-myofibroblast transition. Adv Sci (Weinh) 9: e2101235.
Scheibe, K., C. Kersten, A. Schmied, et al. 2019. Inhibiting interleukin 36 receptor signaling reduces fibrosis in mice with chronic intestinal Inflammation. Gastroenterology 156: 1082–1097.e1011.
Article CAS PubMed Google Scholar
Tang, P.M., S. Zhou, C.J. Li, et al. 2018. The proto-oncogene tyrosine protein kinase Src is essential for macrophage-myofibroblast transition during renal scarring. Kidney International 93: 173–187.
Article CAS PubMed Google Scholar
Wirtz, S.P.V., M. Kindermann, et al. 2017. Chemically induced mouse models of acute and chronic intestinal inflammation. Nature Protocols 12: 1295–1309.
Article CAS PubMed Google Scholar
Vallance, B.A., M.I. Gunawan, B. Hewlett, et al. 2005. TGF-beta1 gene transfer to the mouse colon leads to intestinal fibrosis. American Journal of Physiology. Gastrointestinal and Liver Physiology 289: G116–128.
Article CAS PubMed Google Scholar
Tang, P.M., Y.Y. Zhang, and J. Xiao. 2020. Neural transcription factor Pou4f1 promotes renal fibrosis via macrophage-myofibroblast transition. Proc Natl Acad Sci U S A 117: 20741–20752.
Article CAS PubMed PubMed Central Google Scholar
Airaksinen, M.S., and M. Saarma. 2002. The GDNF family: Signalling, biological functions and therapeutic value. Nature Reviews Neuroscience 3: 383–394.
Article CAS PubMed Google Scholar
Meir, M., S. Flemming, N. Burkard, et al. 2016. The glial cell-line derived neurotrophic factor: A novel regulator of intestinal barrier function in health and disease. American Journal of Physiology. Gastrointestinal and Liver Physiology 310: G1118–1123.
Ibáñez, C.F., and J.O. Andressoo. 2017. Biology of GDNF and its receptors - relevance for disorders of the central nervous system. Neurobiology of Diseases 97: 80–89.
Mulligan, L.M. 2018. GDNF and the RET receptor in cancer: New insights and therapeutic potential. Frontiers in Physiology 9: 1873.
Meir, M., N. Burkard, H. Ungewiß, et al. 2019. Neurotrophic factor GDNF regulates intestinal barrier function in inflammatory bowel disease. The Journal of Clinical Investigation 129: 2824–2840.
Article PubMed PubMed Central Google Scholar
Haberman, Y., P. Minar, R. Karns, et al. 2020. Mucosal inflammatory and wound healing gene programs reveal targets for stricturing behavior in pediatric crohn’s disease. Journal of Crohn’s & Colitis 15: 273–286.
Vierhout, M., A. Ayoub, S. Naiel, et al. 2021. Monocyte and macrophage derived myofibroblasts: Is it fate? A review of the current evidence. Wound Repair Regen 29: 548–562.
Tang, P.M., D.J. Nikolic-Paterson, and H.Y. Lan. 2019. Macrophages: Versatile players in renal inflammation and fibrosis. Nature Reviews. Nephrology 15: 144–158.
Hu, M., Z. Yao, L. Xu, et al. 2023. M2 macrophage polarization in systemic sclerosis fibrosis: Pathogenic mechanisms and therapeutic effects. Heliyon 9: e16206.
Article CAS PubMed PubMed Central Google Scholar
Wang, Z., K. Du, N. Jin, B. Tang, and W. Zhang. 2023. Macrophage in liver fibrosis: Identities and mechanisms. International Immunopharmacology 120: 110357.
Article CAS PubMed Google Scholar
Hu, X., C. Han, J. Jin, et al. 2016. Integrin CD11b attenuates colitis by strengthening Src-Akt pathway to polarize anti-inflammatory IL-10 expression. Science and Reports 6: 26252.
Xue HH, Li JJ, Li SF, et al (2023) Phillygenin attenuated colon inflammation and improved intestinal mucosal barrier in DSS-induced colitis mice via TLR4/Src mediated MAPK and NF-κB signaling pathways. International Journal of Molecular Sciences 24:2238.
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