Bianchi M, D’Oria V, Braghini MR, Petrini S, Manco M (2019) Liraglutide treatment ameliorates neurotoxicity induced by stable silencing of Pin1. Int J Mol Sci 20:5024

Bjørnholm KD, Skovsted GF, Mitgaard-Thomsen A, Rakipovski G, Tveden-Nyborg P, Lykkesfeldt J, Povlsen GK (2021) Liraglutide treatment improves endothelial function in the Ldlr-/- mouse model of atherosclerosis and affects genes involved in vascular remodelling and inflammation. Basic Clin Pharmacol Toxicol 128:103–114

Article  PubMed  Google Scholar 

Boschen KE, Ptacek TS, Berginski ME, Simon JM, Parnell SE (2021) Transcriptomic analyses of gastrulation-stage mouse embryos with differential susceptibility to alcohol. Dis Model Mech 14:dmm049012

Cao X, Fang X, Guo M, Li X, He Y, Xie M, Xu Y, Liu X (2021) TRB3 mediates vascular remodeling by activating the MAPK signaling pathway in hypoxic pulmonary hypertension. Respir Res 22:312

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chen QZ, Chen Y, Li X, Liu H, Sun XL (2022) TRIB3 interacts with STAT3 to promote cancer angiogenesis. Curr Med Sci 42:932–940

Article  CAS  PubMed  Google Scholar 

Chipuk JE (2015) BCL-2 proteins: melanoma lives on the edge. Oncoscience 2:729–730

Article  PubMed  PubMed Central  Google Scholar 

Danilova T, Lindahl M (2018) Emerging roles for mesencephalic astrocyte-derived neurotrophic factor (MANF) in pancreatic beta cells and diabetes. Front Physiol 9:1457

Article  PubMed  PubMed Central  Google Scholar 

Deng C, Cao J, Han J, Li J, Li Z, Shi N, He J (2018) Liraglutide activates the Nrf2/HO-1 antioxidant pathway and protects brain nerve cells against cerebral ischemia in diabetic rats. Comput Intell Neurosci 2018:3094504

Article  PubMed  PubMed Central  Google Scholar 

Ding X, Yao W, Zhu J, Mu K, Zhang J, Zhang JA (2020) Resveratrol attenuates high glucose-induced vascular endothelial cell injury by activating the E2F3 pathway. Biomed Res Int 2020:6173618

Article  PubMed  PubMed Central  Google Scholar 

Dong S, Xia J, Wang H, Sun L, Wu Z, Bin J, Liao Y, Li N, Liao W (2016) Overexpression of TRIB3 promotes angiogenesis in human gastric cancer. Oncol Rep 36:2339–2348

Article  CAS  PubMed  Google Scholar 

Guo L, Guo ZX, Gong HP, Shang YY, Zhong M, Zhang Y, Zhang W (2015) Tribbles homolog 3 is induced by high glucose and associated with apoptosis in human endothelial cells. Mol Med Rep 12:1963–1970

Article  CAS  PubMed  Google Scholar 

Knapp M, Tu X, Wu R (2019) Vascular endothelial dysfunction, a major mediator in diabetic cardiomyopathy. Acta Pharmacol Sin 40:1–8

Article  CAS  PubMed  Google Scholar 

Le Y, Wei R, Yang K, Lang S, Gu L, Liu J, Hong T, Yang J (2020) Liraglutide ameliorates palmitate-induced oxidative injury in islet microvascular endothelial cells through GLP-1 receptor/PKA and GTPCH1/eNOS signaling pathways. Peptides 124:170212

Article  CAS  PubMed  Google Scholar 

Luo M, Sun Q, Zhao H, Tao J, Yan D (2019) The effects of dimethyl fumarate on atherosclerosis in the apolipoprotein E-deficient mouse model with streptozotocin-induced hyperglycemia mediated by the nuclear factor erythroid 2-related factor 2/antioxidant response element (Nrf2/ARE) signaling pathway. Med Sci Monit 25:7966–7975

Article  CAS  PubMed  PubMed Central  Google Scholar 

Luo M, Hu Y, Lv D, Xie L, Yang S, Zuo D, Xue Y, He A (2022) Recurrent hypoglycemia impaired vascular function in advanced T2DM rats by inducing pyroptosis. Oxid Med Cell Longev 2022:7812407

Article  PubMed  PubMed Central  Google Scholar 

Mazzoli V, Zhong LH, Dang VT, Shi Y, Werstuck GH (2020) Characterization of retinal microvascular complications and the effects of endoplasmic reticulum stress in mouse models of diabetic atherosclerosis. Invest Ophthalmol vis Sci 61:49

Article  CAS  PubMed  PubMed Central  Google Scholar 

Peng F, Chang W, Sun Q, Xu X, Xie J, Qiu H, Yang Y (2020) HGF alleviates septic endothelial injury by inhibiting pyroptosis via the mTOR signalling pathway. Respir Res 21:215

Article  CAS  PubMed  PubMed Central  Google Scholar 

Prudente S, Sesti G, Pandolfi A, Andreozzi F, Consoli A, Trischitta V (2012) The mammalian tribbles homolog TRIB3, glucose homeostasis, and cardiovascular diseases. Endocr Rev 33:526–546

Article  CAS  PubMed  PubMed Central  Google Scholar 

Redza-Dutordoir M, Averill-Bates DA (2016) Activation of apoptosis signalling pathways by reactive oxygen species. Biochim Biophys Acta 1863:2977–2992

Article  CAS  PubMed  Google Scholar 

Shi L, Li Y, Shi M, Li X, Li G, Cen J, Liu D, Wei C, Lin Y (2022) Hsa_circRNA_0008028 deficiency ameliorates high glucose-induced proliferation, calcification, and autophagy of vascular smooth muscle cells via miR-182-5p/TRIB3 axis. Oxid Med Cell Longev 2022:5142381

Article  PubMed  PubMed Central  Google Scholar 

Su J, Yan Y, Qu J, Xue X, Liu Z, Cai H (2017) Emodin induces apoptosis of lung cancer cells through ER stress and the TRIB3/NF-κB pathway. Oncol Rep 37:1565–1572

Article  PubMed  Google Scholar 

Suryavanshi SV, Kulkarni YA (2017) NF-κβ: a potential target in the management of vascular complications of diabetes. Front Pharmacol 8:798

Article  PubMed  PubMed Central  Google Scholar 

Tsai TH, Lee CH, Cheng CI, Fang YN, Chung SY, Chen SM, Lin CJ, Wu CJ, Hang CL, Chen WY (2019) Liraglutide inhibits endothelial-to-mesenchymal transition and attenuates neointima formation after endovascular injury in streptozotocin-induced diabetic mice. Cells 8:589

Volpe CMO, Villar-Delfino PH, Dos Anjos PMF, Nogueira-Machado JA (2018) Cellular death, reactive oxygen species (ROS) and diabetic complications. Cell Death Dis 9:119

Article  PubMed  PubMed Central  Google Scholar 

Wils J, Favre J, Bellien J (2017) Modulating putative endothelial progenitor cells for the treatment of endothelial dysfunction and cardiovascular complications in diabetes. Pharmacol Ther 170:98–115

Article  CAS  PubMed  Google Scholar 

Xi J, Rong Y, Zhao Z, Huang Y, Wang P, Luan H, Xing Y, Li S, Liao J, Dai Y, Liang J, Wu F (2021) Scutellarin ameliorates high glucose-induced vascular endothelial cells injury by activating PINK1/Parkin-mediated mitophagy. J Ethnopharmacol 271:113855

Article  CAS  PubMed  Google Scholar 

Yu Y, Qiu L, Guo J, Yang D, Qu L, Yu J, Zhan F, Xue M, Zhong M (2015) TRIB3 mediates the expression of Wnt5a and activation of nuclear factor-κB in Porphyromonas endodontalis lipopolysaccharide-treated osteoblasts. Mol Oral Microbiol 30:295–306

Article  CAS  PubMed  Google Scholar 

Zhang H, Xiong Z, Wang J, Zhang S, Lei L, Yang L, Zhang Z (2016a) Glucagon-like peptide-1 protects cardiomyocytes from advanced oxidation protein product-induced apoptosis via the PI3K/Akt/Bad signaling pathway. Mol Med Rep 13:1593–1601

Article  CAS  PubMed  Google Scholar 

Zhang Y, Zhou H, Wu W, Shi C, Hu S, Yin T, Ma Q, Han T, Zhang Y, Tian F, Chen Y (2016b) Liraglutide protects cardiac microvascular endothelial cells against hypoxia/reoxygenation injury through the suppression of the SR-Ca(2+)-XO-ROS axis via activation of the GLP-1R/PI3K/Akt/survivin pathways. Free Radic Biol Med 95:278–292

Article  CAS  PubMed  Google Scholar 

Zhang Q, Lenardo MJ, Baltimore D (2017) 30 years of NF-κB: a blossoming of relevance to human pathobiology. Cell 168:37–57

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhang Q, Xiao X, Zheng J, Li M, Yu M, Ping F, Wang T, Wang X (2018) Liraglutide protects cardiac function in diabetic rats through the PPARα pathway. Biosci Rep 38:BSR20180059

Zheng Y, Ley SH, Hu FB (2018) Global aetiology and epidemiology of type 2 diabetes mellitus and its complications. Nat Rev Endocrinol 14:88–98

Article  PubMed  Google Scholar 

Zhou Y, Zhou C, Zhang X, Vong CT, Wang Y, Cheang WS (2021) Coptisine attenuates diabetes-associated endothelial dysfunction through inhibition of endoplasmic reticulum stress and oxidative stress. Molecules 26:4210