Bezzi P, Domercq M, Brambilla L, Galli R, Schols D, De Clercq E, Vescovi A, Bagetta G, Kollias G, Meldolesi J, Volterra A (2001) CXCR4-activated astrocyte glutamate release via TNFalpha: amplification by microglia triggers neurotoxicity. Nat Neurosci 4(7):702–710. https://doi.org/10.1038/89490. PMID: 11426226

Article  CAS  PubMed  Google Scholar 

Britton C, Poznansky MC, Reeves P (2021) Polyfunctionality of the CXCR4/CXCL12 axis in health and disease: Implications for therapeutic interventions in cancer and immune-mediated diseases. FASEB J 35(4):e21260. https://doi.org/10.1096/fj.202001273R. PMID: 33715207

Article  CAS  PubMed  Google Scholar 

Cheng X, Wang H, Zhang X, Zhao S, Zhou Z, Mu X, Zhao C, Teng W (2017) The Role of SDF-1/CXCR4/CXCR7 in Neuronal Regeneration after Cerebral Ischemia. Front Neurosci 24(11):590. https://doi.org/10.3389/fnins.2017.00590. PMID: 29123467; PMCID: PMC5662889

Article  Google Scholar 

Choi SS, Lee HJ, Lim I, Satoh J, Kim SU (2014) Human astrocytes: secretome profiles of cytokines and chemokines. PLoS ONE 9(4):e92325. https://doi.org/10.1371/journal.pone.0092325. PMID: 24691121; PMCID: PMC3972155

Article  CAS  PubMed  PubMed Central  Google Scholar 

Donà E, Barry JD, Valentin G, Quirin C, Khmelinskii A, Kunze A, Durdu S, Newton LR, Fernandez-Minan A, Huber W, Knop M, Gilmour D (2013) Directional tissue migration through a self-generated chemokine gradient. Nature 503(7475):285–289. https://doi.org/10.1038/nature12635. Epub 2013 Sep 25 PMID: 24067609

Article  CAS  PubMed  Google Scholar 

Dozio V, Sanchez JC (2018) Profiling the proteomic inflammatory state of human astrocytes using DIA mass spectrometry. J Neuroinflammation 15(1):331. https://doi.org/10.1186/s12974-018-1371-6. PMID: 30501627; PMCID: PMC6267034

Article  CAS  PubMed  PubMed Central  Google Scholar 

Elain G, Jeanneau K, Rutkowska A, Mir AK, Dev KK (2014) The selective anti-IL17A monoclonal antibody secukinumab (AIN457) attenuates IL17A-induced levels of IL6 in human astrocytes. Glia 62(5):725–735. https://doi.org/10.1002/glia.22637. PMID: 24677511

Article  PubMed  Google Scholar 

Escartin C, Galea E, Lakatos A, O’Callaghan JP, Petzold GC, Serrano-Pozo A, Steinhäuser C, Volterra A, Carmignoto G, Agarwal A, Allen NJ, Araque A, Barbeito L, Barzilai A, Bergles DE, Bonvento G, Butt AM, Chen WT, Cohen-Salmon M, Cunningham C, Deneen B, De Strooper B, Díaz-Castro B, Farina C, Freeman M, Gallo V, Goldman JE, Goldman SA, Götz M, Gutiérrez A, Haydon PG, Heiland DH, Hol EM, Holt MG, Iino M, Kastanenka KV, Kettenmann H, Khakh BS, Koizumi S, Lee CJ, Liddelow SA, MacVicar BA, Magistretti P, Messing A, Mishra A, Molofsky AV, Murai KK, Norris CM, Okada S, Oliet SHR, Oliveira JF, Panatier A, Parpura V, Pekna M, Pekny M, Pellerin L, Perea G, Pérez-Nievas BG, Pfrieger FW, Poskanzer KE, Quintana FJ, Ransohoff RM, Riquelme-Perez M, Robel S, Rose CR, Rothstein JD, Rouach N, Rowitch DH, Semyanov A, Sirko S, Sontheimer H, Swanson RA, Vitorica J, Wanner IB, Wood LB, Wu J, Zheng B, Zimmer ER, Zorec R, Sofroniew MV, Verkhratsky A (2021) Reactive astrocyte nomenclature, definitions, and future directions. Nat Neurosci 24(3):312–325. https://doi.org/10.1038/s41593-020-00783-4. Epub 2021. PMID: 33589835; PMCID: PMC80070811.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Falsig J, Pörzgen P, Lund S, Schrattenholz A, Leist M (2006) The inflammatory transcriptome of reactive murine astrocytes and implications for their innate immune function. J Neurochem 96(3):893–907. https://doi.org/10.1111/j.1471-4159.2005.03622.x. Epub 2006 Jan 9 PMID: 16405499

Article  CAS  PubMed  Google Scholar 

Fumagalli A, Heuninck J, Pizzoccaro A, Moutin E, Koenen J, Séveno M, Durroux T, Junier MP, Schlecht-Louf G, Bachelerie F, Schütz D, Stumm R, Smit MJ, Guérineau NC, Chaumont-Dubel S, Marin P (2020) The atypical chemokine receptor 3 interacts with Connexin 43 inhibiting astrocytic gap junctional intercellular communication. Nat Commun 11(1):4855. https://doi.org/10.1038/s41467-020-18634-y. PMID: 32978390; PMCID: PMC7519114

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gentilini A, Caligiuri A, Raggi C, Rombouts K, Pinzani M, Lori G, Correnti M, Invernizzi P, Rovida E, Navari N, Di Matteo S, Alvaro D, Banales JM, Rodrigues P, Raschioni C, Donadon M, Di Tommaso L, Marra F (2019) CXCR7 contributes to the aggressive phenotype of cholangiocarcinoma cells. Biochim Biophys Acta Mol Basis Dis 1865(9):2246–2256. https://doi.org/10.1016/j.bbadis.2019.04.020. Epub 2019 May 3 PMID: 31059778

Article  CAS  PubMed  Google Scholar 

Gotoh M, Miyamoto Y, Ikeshima-Kataoka H (2023) Astrocytic Neuroimmunological Roles Interacting with Microglial Cells in Neurodegenerative Diseases. Int J Mol Sci 24(2):1599. https://doi.org/10.3390/ijms24021599. PMID: 36675113; PMCID: PMC9865248

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hamby ME, Coppola G, Ao Y, Geschwind DH, Khakh BS, Sofroniew MV (2012) Inflammatory mediators alter the astrocyte transcriptome and calcium signaling elicited by multiple G-protein-coupled receptors. J Neurosci 32(42):14489–14510. https://doi.org/10.1523/JNEUROSCI.1256-12.2012. PMID: 23077035; PMCID: PMC3518872

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hyvärinen T, Hagman S, Ristola M, Sukki L, Veijula K, Kreutzer J, Kallio P, Narkilahti S (2019) Co-stimulation with IL-1β and TNF-α induces an inflammatory reactive astrocyte phenotype with neurosupportive characteristics in a human pluripotent stem cell model system. Sci Rep 9(1):16944. https://doi.org/10.1038/s41598-019-53414-9

Article  CAS  PubMed  PubMed Central  Google Scholar 

Jaerve A, Müller HW (2012) Chemokines in CNS injury and repair. Cell Tissue Res 349(1):229–248. https://doi.org/10.1007/s00441-012-1427-3. Epub 2012 May 22 PMID: 22700007

Article  CAS  PubMed  Google Scholar 

Jana M, Anderson JA, Saha RN, Liu X, Pahan K (2004) Regulation of inducible nitric oxide synthase in proinflammatory cytokine-stimulated human primary astrocytes. Free Radic Biol Med 38(5):655–664. https://doi.org/10.1016/j.freeradbiomed.2004.11.021. PMID: 15683721

Article  CAS  Google Scholar 

Jiang Q, Gingles NA, Olivier MA, Miles LA, Parmer RJ (2011) The anti-fibrinolytic SERPIN, plasminogen activator inhibitor 1 (PAI-1), is targeted to and released from catecholamine storage vesicles. Blood 117(26):7155–63. https://doi.org/10.1182/blood-2010-05-287672. Epub 2011. PMID: 21596853; PMCID: PMC3143556

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kariya Y, Kariya Y, Saito T, Nishiyama S, Honda T, Tanaka K, Yoshida M, Fujihara K, Hashimoto Y (2015) Increased cerebrospinal fluid osteopontin levels and its involvement in macrophage infiltration in neuromyelitis optica. BBA Clin 15(3):126–134. https://doi.org/10.1016/j.bbacli.2015.01.003. PMID: 26673877; PMCID: PMC4661545

Article  Google Scholar 

Koch C, Engele J (2020) Functions of the CXCL12 Receptor ACKR3/CXCR7-What Has Been Perceived and What Has Been Overlooked. Mol Pharmacol 98(5):577–585. https://doi.org/10.1124/molpharm.120.000056. Epub 2020 Sep 3 PMID: 32883765

Article  CAS  PubMed  Google Scholar 

Korbecki J, Gąssowska-Dobrowolska M, Wójcik J, Szatkowska I, Barczak K, Chlubek M, Baranowska-Bosiacka I (2022) The Importance of CXCL1 in Physiology and Noncancerous Diseases of Bone, Bone Marrow, Muscle and the Nervous System. Int J Mol Sci 23(8):4205. https://doi.org/10.3390/ijms23084205. PMID: 35457023; PMCID: PMC9024980

Article  CAS  PubMed  PubMed Central  Google Scholar 

Koyama Y, Endothelin ETB (2021) Receptor-Mediated Astrocytic Activation: Pathological Roles in Brain Disorders. Int J Mol Sci 22(9):4333. https://doi.org/10.3390/ijms22094333. PMID: 33919338; PMCID: PMC8122402

Article  CAS  PubMed  PubMed Central  Google Scholar 

Le Magueresse-Battistoni B, Pernod G, Sigillo F, Kolodié L, Benahmed M (1998) Plasminogen activator inhibitor-1 is expressed in cultured rat Sertoli cells. Biol Reprod 59(3):591–598. https://doi.org/10.1095/biolreprod59.3.591. PMID: 9716558

Article  PubMed  Google Scholar 

Lee E, Han J, Kim K, Choi H, Cho EG, Lee TR (2013) CXCR7 mediates SDF1-induced melanocyte migration. Pigment Cell Melanoma Res 26(1):58–66. https://doi.org/10.1111/pcmr.12024. Epub 2012 Oct 26 PMID: 22978759

Article  CAS  PubMed  Google Scholar 

Lemaître F, Farzam-Kia N, Carmena Moratalla A, Carpentier Solorio Y, Clenet ML, Tastet O, Cleret-Buhot A, Guimond JV, Haddad E, Duquette P, Girard JM, Prat A, Larochelle C, Arbour N (2022) IL-27 shapes the immune properties of human astrocytes and their impact on encountered human T lymphocytes. J Neuroinflammation 19(1):212. https://doi.org/10.1186/s12974-022-02572-1. PMID: 36050707; PMCID: PMC9434874

Article  CAS  PubMed  PubMed Central  Google Scholar 

Liang Z, Lou Y, Hao Y, Li H, Feng J, Liu S (2023) The Relationship of Astrocytes and Microglia with Different Stages of Ischemic Stroke. Curr Neuropharmacol 18. https://doi.org/10.2174/1570159X21666230718104634. Epub ahead of print. PMID: 37464832.