Urinary polycyclic aromatic hydrocarbon metabolites and hyperlipidemia: NHANES 2007–2016

Laufs U, Parhofer KG, Ginsberg HN, Hegele RA. Clinical review on triglycerides. Eur Heart J. 2020;41(1):99–c109.

Article  CAS  PubMed  Google Scholar 

Su X, Peng H, Chen X, Wu X, Wang B. Hyperlipidemia and hypothyroidism. Clin Chim Acta. 2022;527:61–70.

Article  CAS  PubMed  Google Scholar 

Pirillo A, Casula M, Olmastroni E, Norata GD, Catapano AL. Global epidemiology of dyslipidaemias. Nat Rev Cardiol. 2021;18(10):689–700.

Article  CAS  PubMed  Google Scholar 

Gaggini M, Gorini F, Vassalle C. Lipids in Atherosclerosis: Pathophysiology and the Role of Calculated Lipid Indices in Assessing Cardiovascular Risk in Patients with Hyperlipidemia. Int J Mol Sci. 2022;24(1):75.

Article  PubMed  PubMed Central  Google Scholar 

Tsao CW, Aday AW, Almarzooq ZI, Alonso A, Beaton AZ, Bittencourt MS, et al. Heart Disease and Stroke Statistics-2022 update: a Report from the American Heart Association. Circulation. 2022;145(8):e153–639.

Article  PubMed  Google Scholar 

Ma J, Hao X, Nie X, Yang S, Zhou M, Wang D, et al. Longitudinal relationships of polycyclic aromatic hydrocarbons exposure and genetic susceptibility with blood lipid profiles. Environ Int. 2022;164:107259.

Article  CAS  PubMed  Google Scholar 

Mallah MA, Changxing L, Mallah MA, Noreen S, Liu Y, Saeed M, et al. Polycyclic aromatic hydrocarbon and its effects on human health: an overeview. Chemosphere. 2022;296:133948.

Article  CAS  PubMed  Google Scholar 

Sun S, Mao W, Tao S, Zou X, Tian S, Qian S, et al. Polycyclic Aromatic Hydrocarbons and the risk of kidney stones in US adults: an exposure-response analysis of NHANES 2007–2012. Int J Gen Med. 2021;14:2665–76.

Article  PubMed  PubMed Central  Google Scholar 

Yang X, Xue Q, Wen Y, Huang Y, Wang Y, Mahai G, et al. Environmental polycyclic aromatic hydrocarbon exposure in relation to metabolic syndrome in US adults. Sci Total Environ. 2022;840:156673.

Article  CAS  PubMed  Google Scholar 

Wang F, Wang Y, Wang Y, Jia T, Chang L, Ding J, et al. Urinary polycyclic aromatic hydrocarbon metabolites were associated with hypertension in US adults: data from NHANES 2009–2016. Environ Sci Pollut Res Int. 2022;29(53):80491–501.

Article  CAS  PubMed  Google Scholar 

Huang X, Deng X, Li W, Liu S, Chen Y, Yang B, et al. Internal exposure levels of polycyclic aromatic hydrocarbons in children and adolescents: a systematic review and meta-analysis. Environ Health Prev Med. 2019;24(1):50.

Article  PubMed  PubMed Central  Google Scholar 

Mallah MA, Changxing L, Mallah MA, Naveed M, Liu Y, Noreen S, et al. Association of urinary polycyclic aromatic hydrocarbon metabolites and cardiovascular disease among US population: a cross-sectional study. Environ Res. 2022;209:112775.

Article  CAS  PubMed  Google Scholar 

Alshaarawy O, Zhu M, Ducatman AM, Conway B, Andrew ME. Urinary polycyclic aromatic hydrocarbon biomarkers and diabetes mellitus. Occup Environ Med. 2014;71(6):437–41.

Article  CAS  PubMed  Google Scholar 

White AJ, Bradshaw PT, Herring AH, Teitelbaum SL, Beyea J, Stellman SD, et al. Exposure to multiple sources of polycyclic aromatic hydrocarbons and breast cancer incidence. Environ Int. 2016;89–90:185–92.

Article  PubMed  PubMed Central  Google Scholar 

Stading R, Gastelum G, Chu C, Jiang W, Moorthy B. Molecular mechanisms of pulmonary carcinogenesis by polycyclic aromatic hydrocarbons (PAHs): implications for human lung cancer. Semin Cancer Biol. 2021;76:3–16.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ma J, Zhou Y, Liu Y, Xiao L, Cen X, Li W, et al. Association between urinary polycyclic aromatic hydrocarbon metabolites and dyslipidemias in the Chinese general population: a cross-sectional study. Environ Pollut. 2019;245:89–97.

Article  CAS  PubMed  Google Scholar 

Jin Y, Miao W, Lin X, Wu T, Shen H, Chen S, et al. Sub-chronically exposing mice to a polycyclic aromatic hydrocarbon increases lipid accumulation in their livers. Environ Toxicol Pharmacol. 2014;38(2):353–63.

Article  CAS  PubMed  Google Scholar 

Li F, Xiang B, Jin Y, Li C, Li J, Ren S, et al. Dysregulation of lipid metabolism induced by airway exposure to polycyclic aromatic hydrocarbons in C57BL/6 mice. Environ Pollut. 2019;245:986–93.

Article  CAS  PubMed  Google Scholar 

Hu H, Kan H, Kearney GD, Xu X. Associations between exposure to polycyclic aromatic hydrocarbons and glucose homeostasis as well as metabolic syndrome in nondiabetic adults. Sci Total Environ. 2015;505:56–64.

Article  CAS  PubMed  Google Scholar 

Alshaarawy O, Elbaz HA, Andrew ME. The association of urinary polycyclic aromatic hydrocarbon biomarkers and cardiovascular disease in the US population. Environ Int. 2016;89–90:174–8.

Article  PubMed  PubMed Central  Google Scholar 

Mallah MA, Basnet TB, Ali M, Xie F, Li X, Feng F, et al. Association between urinary polycyclic aromatic hydrocarbon metabolites and diabetes mellitus among the US population: a cross-sectional study. Int Health. 2023;15(2):161–70.

Article  PubMed  Google Scholar 

Third Report of the National Cholesterol Education Program (NCEP). Expert Panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III) final report. Circulation. 2002;106(25):3143–421.

Article  Google Scholar 

Han Y, Jiang X, Qin Y, Zhao Y, Zhang G, Liu C. A cross-sectional study exploring the relationship between the dietary inflammatory index and hyperlipidemia based on the National Health and Nutrition Examination Survey (2005–2018). Lipids Health Dis. 2023;22(1):140.

Article  PubMed  PubMed Central  Google Scholar 

Zhang Y, Liu W, Zhang W, Cheng R, Tan A, Shen S, et al. Association between blood lead levels and hyperlipidemiais: results from the NHANES (1999–2018). Front Public Health. 2022;10:981749.

Article  PubMed  PubMed Central  Google Scholar 

Ranjbar M, Rotondi MA, Ardern CI, Kuk JL. Urinary biomarkers of polycyclic aromatic hydrocarbons are associated with cardiometabolic health risk. PLoS ONE. 2015;10(9):e0137536.

Article  PubMed  PubMed Central  Google Scholar 

Stallings-Smith S, Mease A, Johnson TM, Arikawa AY. Exploring the association between polycyclic aromatic hydrocarbons and diabetes among adults in the United States. Environ Res. 2018;166:588–94.

Article  CAS  PubMed  Google Scholar 

Carrico C, Gennings C, Wheeler DC, Factor-Litvak P. Characterization of Weighted Quantile Sum Regression for highly correlated data in a risk analysis setting. J Agric Biol Environ Stat. 2015;20(1):100–20.

Article  PubMed  Google Scholar 

Karr S. Epidemiology and management of hyperlipidemia. Am J Manag Care. 2017;23(9 Suppl):S139–48.

PubMed  Google Scholar 

Acharya N, Gautam B, Subbiah S, Rogge MM, Anderson TA, Gao W. Polycyclic aromatic hydrocarbons in breast milk of obese vs normal women: infant exposure and risk assessment. Sci Total Environ. 2019;668:658–67.

Article  CAS  PubMed  Google Scholar 

Sousa S, Paíga P, Pestana D, Faria G, Delerue-Matos C, Ramalhosa MJ, et al. Evaluating the impact of polycyclic aromatic hydrocarbon bioaccumulation in adipose tissue of obese women. Chemosphere. 2024;353:141673.

Article  CAS  PubMed  Google Scholar 

Wang Y, Zhu L, James-Todd T, Sun Q. Urinary polycyclic aromatic hydrocarbon excretion and regional body fat distribution: evidence from the U.S. National Health and Nutrition Examination Survey 2001–2016. Environ Health. 2022;21(1):75.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Alhamdow A, Lindh C, Albin M, Gustavsson P, Tinnerberg H, Broberg K. Early markers of cardiovascular disease are associated with occupational exposure to polycyclic aromatic hydrocarbons. Sci Rep. 2017;7(1):9426.

Article  PubMed  PubMed Central  Google Scholar 

Hýžd’alová M, Pivnicka J, Zapletal O, Vázquez-Gómez G, Matthews J, Neca J, et al. Aryl Hydrocarbon receptor-dependent metabolism plays a significant role in Estrogen-Like effects of Polycyclic Aromatic hydrocarbons on Cell Proliferation. Toxicol Sci. 2018;165(2):447–61.

Article  PubMed  PubMed Central  Google Scholar 

Sun H, Shen OX, Xu XL, Song L, Wang XR. Carbaryl, 1-naphthol and 2-naphthol inhibit the beta-1 thyroid hormone receptor-mediated transcription in vitro. Toxicology. 2008;249(2–3):238–42.

Article  CAS  PubMed  Google Scholar 

Schultz TW, Sinks GD. Xenoestrogenic gene expression: structural features of active polycyclic aromatic hydrocarbons. Environ Toxicol Chem. 2002;21(4):783–6.

Article  CAS  PubMed  Google Scholar 

Irigaray P, Ogier V, Jacquenet S, Notet V, Sibille P, Méjean L, et al. Benzo[a]pyrene impairs beta-adrenergic stimulation of adipose tissue lipolysis and causes weight gain in mice. A novel molecular mechanism of toxicity for a common food pollutant. Febs j. 2006;273(7):1362–72.

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