Psychological Health and Ischemic Heart Disease in Women: A Review of Current Evidence and Clinical Considerations across the Healthspan

World Health Organization. Mental health: strengthening our response. https://cdn.ymaws.com/www.safestates.org/resource/resmgr/connections_lab/glossary_citation/mental_health_strengthening.pdf. Accessed 9 Sep 2023.

Levine GN, Cohen BE, Commodore-Mensah Y, Fleury J, Huffman JC, Khalid U, et al. Psychological health, well-being, and the mind-heart-body connection: a scientific statement from the American Heart Association. Circulation. 2021;143(10):e763–83. https://doi.org/10.1161/CIR.0000000000000947.

Article  PubMed  Google Scholar 

Lloyd-Jones DM, Allen NB, Anderson CA, Black T, Brewer LC, Foraker RE, et al. Life’s essential 8: updating and enhancing the American Heart Association’s construct of cardiovascular health: a presidential advisory from the American Heart Association. Circulation. 2022;146(5):e18–43. https://doi.org/10.1161/CIR.0000000000001078.

Article  PubMed  PubMed Central  Google Scholar 

Virani SS, Newby LK, Arnold SV, Bittner V, Brewer LC, Demeter SH, et al. 2023 AHA/ACC/ACCP/ASPC/NLA/PCNA guideline for the management of patients with chronic coronary disease: a report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines. J Am Coll Cardiol. 2023;148:e9–119. https://doi.org/10.1161/CIR.0000000000001168.

Article  Google Scholar 

O’Neil A, Russell JD, Murphy B. How does mental health impact women’s heart health? Heart Lung Circ. 2021;30(1):59–68. https://doi.org/10.1016/j.hlc.2020.05.111.

Article  PubMed  Google Scholar 

Majidi M, Eslami V, Ghorbani P, Foroughi M. Are women more susceptible to ischemic heart disease compared to men? A literature overview. J Geriatr Cardiol. 2021;18(4):289–296. https://doi.org/10.11909/j.issn.1671-5411.2021.04.004.

Connelly PJ, Azizi Z, Alipour P, Delles C, Pilote L, Raparelli V. The importance of gender to understand sex differences in cardiovascular disease. Can J Cardiol. 2021;37(5):699–710. https://doi.org/10.1016/j.cjca.2021.02.005.

Article  PubMed  Google Scholar 

Olsson A, Mohammad MA, Rylance R, Platonov PG, Sparv D, Erlinge D. Sex differences in potential triggers of myocardial infarction. Eur Heart J Open. 2023;3(2):oead011. https://doi.org/10.1093/ehjopen/oead011.

Article  PubMed  PubMed Central  Google Scholar 

Seligowski AV, Ressler KJ. Sex differences in the co-occurrence of PTSD and cardiovascular disease. Psychiatr Ann. 2022;52(1):26–30. https://doi.org/10.3928/00485713-20211226-01.

Article  Google Scholar 

Sullivan S, Young A, Garcia M, Almuwaqqat Z, Moazzami K, Hammadah M, et al. Sex differences in vascular response to mental stress and adverse cardiovascular events among patients with ischemic heart disease. Arterioscler Thromb Vasc Biol. 2023;43(4):e112–20. https://doi.org/10.1161/ATVBAHA.122.318576.

Article  CAS  PubMed  Google Scholar 

Vaccarino V, Badimon L, Corti R, De Wit C, Dorobantu M, Hall A, et al. Ischaemic heart disease in women: are there sex differences in pathophysiology and risk factors? Position paper from the working group on coronary pathophysiology and microcirculation of the European Society of Cardiology. Cardiovasc Res. 2011;90(1):9–17. https://doi.org/10.1093/cvr/cvq394.

Article  CAS  PubMed  Google Scholar 

Smaardijk VR, Lodder P, Kop WJ, van Gennep B, Maas AH, Mommersteeg PM. Sex- and gender-stratified risks of psychological factors for incident ischemic heart disease: systematic review and meta-analysis. J Am Heart Assoc. 2019;8(9):e010859. https://doi.org/10.1161/JAHA.118.010859.

Article  PubMed  PubMed Central  Google Scholar 

Smaardijk VR, Maas AH, Lodder P, Kop WJ, Mommersteeg PM. Sex and gender-stratified risks of psychological factors for adverse clinical outcomes in patients with ischemic heart disease: a systematic review and meta-analysis. Int J Cardiol. 2020;302:21–9. https://doi.org/10.1016/j.ijcard.2019.12.014.

Article  PubMed  Google Scholar 

Boehm JK, Kubzansky LD. Positive psychological well-being and cardiovascular disease. In: Handbook of Cardiovascular Behavioral Medicine. Springer; 2022. p. 541–569.

Kubzansky LD, Huffman JC, Boehm JK, Hernandez R, Kim ES, Koga HK, et al. Positive psychological well-being and cardiovascular disease: JACC health promotion series. J Am Coll Cardiol. 2018;72(12):1382–96. https://doi.org/10.1016/j.jacc.2018.07.042.

Article  PubMed  PubMed Central  Google Scholar 

Labaka A, Goñi-Balentziaga O, Lebeña A, Pérez-Tejada J. Biological sex differences in depression: a systematic review. Biol Res Nurs. 2018;20(4):383–92. https://doi.org/10.1177/1099800418776082.

Article  PubMed  Google Scholar 

Supraja T, Bhargavi C, Chandra PS. Stress among women—causes and consequences. In: Stress and struggles: the comprehensive book on stress, mental health and mental illness. Coventary, England and Bengaluru, India: Indo-UK Stress and Mental Health Group; 2020. pp. 427–449.

Vogel B, Acevedo M, Appelman Y, Merz CNB, Chieffo A, Figtree GA, et al. The Lancet women and cardiovascular disease Commission: reducing the global burden by 2030. Lancet. 2021;397(10292):2385–438. https://doi.org/10.1016/S0140-6736(21)00684-X.

Article  PubMed  Google Scholar 

Brewer LC, Svatikova A, Mulvagh SL. The challenges of prevention, diagnosis and treatment of ischemic heart disease in women. Cardiovasc Drugs Ther. 2015;29(4):355–68. https://doi.org/10.1007/s10557-015-6607-4.

Article  PubMed  PubMed Central  Google Scholar 

Sullivan S, Young A, Garcia M, Almuwaqqat Z, Moazzami K, Hammadah M, et al. Gender disparities between neighborhood social vulnerability and psychological distress among patients with heart disease. J Womens Health. 2022;31(10):1440–9. https://doi.org/10.1089/jwh.2021.0505.

Article  Google Scholar 

Espnes GA, Byrne D. Gender differences in psychological risk factors for development of heart disease. Stress and Health: J International Society Investigation of Stress. 2008;24(3):188–95. https://doi.org/10.1002/smi.1196.

Article  Google Scholar 

Pelletier R, Khan NA, Cox J, Daskalopoulou SS, Eisenberg MJ, Bacon SL, et al. Sex versus gender-related characteristics: which predicts outcome after acute coronary syndrome in the young? J Am Coll Cardiol. 2016;67(2):127–35. https://doi.org/10.1016/j.jacc.2015.10.067.

Article  PubMed  Google Scholar 

Tomaszewski M, Topyła W, Kijewski BG, Miotła P, Waciński P. Does gender influence the outcome of ischemic heart disease? Prz Menopauzalny. 2019;18(1):51–6. https://doi.org/10.5114/pm.2019.84158.

Article  PubMed  PubMed Central  Google Scholar 

Collopy CM, Cosh SM, Tully PJ. Screening and referral is not enough: a qualitative exploration of barriers to access and uptake of mental health services in patients with cardiovascular diseases. BMC Health Serv Res. 2021;21(1):1–11. https://doi.org/10.1186/s12913-020-06030-7.

Article  Google Scholar 

Karami N, Kazeminia M, Karami A, Salimi Y, Ziapour A, Janjani P. Global prevalence of depression, anxiety, and stress in cardiac patients: a systematic review and meta-analysis. J Affect Disord. 2022. https://doi.org/10.1016/j.jad.2022.12.055.

Article  PubMed  Google Scholar 

Schmitt MT, Branscombe NR, Kobrynowicz D, Owen S. Perceiving discrimination against one’s gender group has different implications for well-being in women and men. Pers Soc Psychol Bull. 2002;28(2):197–210. https://doi.org/10.1177/0146167202282006.

Article  Google Scholar 

Li J, Zhang M, Loerbroks A, Angerer P, Siegrist J. Work stress and the risk of recurrent coronary heart disease events: a systematic review and meta-analysis. Int J Occup Med Environ Health. 2015;28(1):8–19. https://doi.org/10.2478/s13382-014-0303-7.

Article  PubMed  Google Scholar 

Power N, Deschênes SS, Ferri F, Schmitz N. Job strain and the incidence of heart diseases: a prospective community study in Quebec. Canada J Psychosom Res. 2020;139:110268. https://doi.org/10.1016/j.jpsychores.2020.110268.

Article  PubMed  Google Scholar 

Bynum L, Griffin T, Riding D, Wynkoop K, Anda R, Edwards V, et al. Adverse childhood experiences reported by adults-five states, 2009. MMWR Morb Mortal Wkly Rep. 2010;59(49):1609–13.

Google Scholar 

Soares ALG, Hammerton G, Howe LD, Rich-Edwards J, Halligan S, Fraser A. Sex differences in the association between childhood maltreatment and cardiovascular disease in the UK Biobank. Heart. 2020;106(17):1310–6. https://doi.org/10.1136/heartjnl-2019-316320.

Article  PubMed  Google Scholar 

Obi IE, McPherson KC, Pollock JS. Childhood adversity and mechanistic links to hypertension risk in adulthood. Br J Pharmacol. 2019;176(12):1932–50. https://doi.org/10.1111/bph.14576.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Suglia SF, Koenen KC, Boynton-Jarrett R, Chan PS, Clark CJ, Danese A, et al. Childhood and adolescent adversity and cardiometabolic outcomes: a scientific statement from the American Heart Association. Circulation. 2018;137(5):e15–28. https://doi.org/10.1161/CIR.0000000000000536.

Article  PubMed  Google Scholar 

Supraja T, Bhargavi C, Chandra PS. Stress among women-causes and consequences. In: Stress and Struggles The Comprehensive Book on Stress, Mental Health and Mental Illness. Coventary, England and Bengaluru, India: Indo-UK Stress and Mental Health Group; 2020. p 427–449.

Helman TJ, Headrick JP, Stapelberg NJ, Braidy N. The sex-dependent response to psychosocial stress and ischaemic heart disease. Front Cardiovasc Med. 2023;10:1072042. https://doi.org/10.3389/fcvm.2023.1072042.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Heck AL, Handa RJ. Sex differences in the hypothalamic–pituitary–adrenal axis’ response to stress: an important role for gonadal hormones. Neuropsychopharmacology. 2019;44(1):45–58. https://doi.org/10.1038/s41386-018-0167-9.

Article  CAS  PubMed  Google Scholar 

Brown EG, Gallagher S, Creaven AM. Loneliness and acute stress reactivity: a systematic review of psychophysiological studies. Psychophysiology. 2018;55(5):e13031. https://doi.org/10.1111/psyp.13031.

Article  PubMed  Google Scholar 

van der Meer RE, Maas AH. The role of mental stress in ischaemia with no obstructive coronary artery disease and coronary vasomotor disorders. Eur Cardiol. 2021;16. https://doi.org/10.15420/ecr.2021.20.

Vaccarino V, Wilmot K, Mheid IA, Ramadan R, Pimple P, Shah AJ, et al. Sex differences in mental stress-induced myocardial ischemia in patients with coronary heart disease. J Am Heart Assoc. 2016;5(9):e003630. https://doi.org/10.1161/jaha.116.003630.

Article  PubMed  PubMed Central  Google Scholar 

Vaccarino V, Shah AJ, Rooks C, Ibeanu I, Nye JA, Pimple P, et al. Sex differences in mental stress-induced myocardial ischemia in young survivors of an acute myocardial infarction. Psychosom Med. 2014;76(3):171. https://doi.org/10.1097/psy.0000000000000045.

Article  CAS  PubMed  PubMed Central 

Comments (0)

No login
gif