Birnie GD (1988) The HL60 cell line: a model system for studying human myeloid cell differentiation. Br J Cancer Suppl 9:41–45

CAS  PubMed  PubMed Central  Google Scholar 

Bradley PP, Priebat DA, Christensen RD, Rothstein G (1982) Measurement of cutaneous inflammation: estimation of neutrophil content with an enzyme marker. J Invest Dermatol 78(3):206–209. https://doi.org/10.1111/1523-1747.ep12506462

Article  CAS  PubMed  Google Scholar 

Brescia G, Barion U, Zanotti C, Cinetto F, Giacomelli L, Martini A, Marioni G (2017) Blood eosinophil-to-basophil ratio in patients with sinonasal polyps: does it have a clinical role? Ann Allergy Asthma Immunol 119(3):223–226. https://doi.org/10.1016/j.anai.2017.06.008

Article  PubMed  Google Scholar 

Carus A, Ladekarl M, Hager H, Nedergaard BS, Donskov F (2013) Tumour-associated CD66b+ neutrophil count is an independent prognostic factor for recurrence in localised cervical cancer. Br J Cancer 108(10):2116–2122. https://doi.org/10.1038/bjc.2013.167

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cox D, Earle L, Jimenez SA, Leiferman KM, Gleich GJ, Varga J (1995) Elevated levels of eosinophil major basic protein in the sera of patients with systemic sclerosis. Arthritis Rheum 38(7):939–945. https://doi.org/10.1002/art.1780380709

Article  CAS  PubMed  Google Scholar 

Delemarre T, Bochner BS, Simon HU, Bachert C (2021) Rethinking neutrophils and eosinophils in chronic rhinosinusitis. J Allergy Clin Immunol 148(2):327–335. https://doi.org/10.1016/j.jaci.2021.03.024

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ecker RC, Steiner GE (2004) Microscopy-based multicolor tissue cytometry at the single-cell level. Cytom A 59(2):182–190. https://doi.org/10.1002/cyto.a.20052

Article  CAS  Google Scholar 

Ecker RC, Rogojanu R, Streit M, Oesterreicher K, Steiner GE (2006) An improved method for discrimination of cell populations in tissue sections using microscopy-based multicolor tissue cytometry. Cytom A 69(3):119–123. https://doi.org/10.1002/cyto.a.20219

Article  Google Scholar 

Fokkens WJ, Lund VJ, Mullol J et al (2012) EPOS 2012: European position paper on rhinosinusitis and nasal polyps 2012. A summary for otorhinolaryngologists. Rhinology 50(1):1–12. https://doi.org/10.4193/Rhino50E2

Article  PubMed  Google Scholar 

Fokkens WJ, Lund VJ, Hopkins C et al (2020) European position paper on rhinosinusitis and nasal polyps 2020. Rhinology 58(Suppl S29):1–464. https://doi.org/10.4193/Rhin20.600

Article  PubMed  Google Scholar 

Ghaye J, Kamat MA, Corbino-Giunta L, Silacci P, Vergeres G, De Micheli G, Carrara S (2013) Image thresholding techniques for localization of sub-resolution fluorescent biomarkers. Cytom A 83(11):1001–1016. https://doi.org/10.1002/cyto.a.22345

Article  CAS  Google Scholar 

Giotakis AI, Dudas J, Glueckert R, Dejaco D, Ingruber J, Fleischer F, Innerhofer V, Pinggera L, Bektic-Tadic L, Gabriel SAM, Riechelmann H (2021) Characterization of epithelial cells, connective tissue cells and immune cells in human upper airway mucosa by immunofluorescence multichannel image cytometry: a pilot study. Histochem Cell Biol 155(3):405–421. https://doi.org/10.1007/s00418-020-01945-y

Article  CAS  PubMed  Google Scholar 

Giotakis AI, Runge A, Dudas J, Glueckert R, Gottfried T, Schartinger VH, Klarer J, Randhawa A, Caimmi E, Riechelmann H (2023) Analysis of cells of epithelial, connective tissue and immune differentiation in HPV-positive-, HPV-negative oropharyngeal carcinoma and normal oropharyngeal tissue by immunofluorescence multiplex image cytometry: a preliminary report. BMC Cancer 23(1):1154. https://doi.org/10.1186/s12885-023-11440-x

Article  CAS  PubMed  PubMed Central  Google Scholar 

Healy S, McMahon J, Owens P, Dockery P, FitzGerald U (2018) Threshold-based segmentation of fluorescent and chromogenic images of microglia, astrocytes and oligodendrocytes in FIJI. J Neurosci Methods 295:87–103. https://doi.org/10.1016/j.jneumeth.2017.12.002

Article  PubMed  Google Scholar 

Husna N, Gascoigne NRJ, Tey HL, Ng LG, Tan Y (2019) Multi-modal image cytometry approach - from dynamic to whole organ imaging. Cell Immunol 344:103946. https://doi.org/10.1016/j.cellimm.2019.103946

Article  CAS  PubMed  Google Scholar 

Ikeda K, Shiozawa A, Ono N, Kusunoki T, Hirotsu M, Homma H, Saitoh T, Murata J (2013) Subclassification of chronic rhinosinusitis with nasal polyp based on eosinophil and neutrophil. Laryngoscope 123(11):E1-9. https://doi.org/10.1002/lary.24154

Article  CAS  PubMed  Google Scholar 

Ishihara K (2014) Eosinophil cell lines. Methods Mol Biol 1178:45–51. https://doi.org/10.1007/978-1-4939-1016-8_5

Article  PubMed  Google Scholar 

Jepsen RK, Klarskov LL, Lippert MF, Novotny GW, Hansen TP, Christensen IJ, Hogdall E, Riis LB (2018) Digital image analysis of pan-cytokeratin stained tumor slides for evaluation of tumor budding in pT1/pT2 colorectal cancer: results of a feasibility study. Pathol Res Pract 214(9):1273–1281. https://doi.org/10.1016/j.prp.2018.07.002

Article  CAS  PubMed  Google Scholar 

Kuhar HN, Tajudeen BA, Mahdavinia M, Gattuso P, Ghai R, Batra PS (2017) Inflammatory infiltrate and mucosal remodeling in chronic rhinosinusitis with and without polyps: structured histopathologic analysis. Int Forum Allergy Rhinol 7(7):679–689. https://doi.org/10.1002/alr.21943

Article  PubMed  Google Scholar 

Lau D, Mollnau H, Eiserich JP, Freeman BA, Daiber A, Gehling UM, Brummer J, Rudolph V, Munzel T, Heitzer T, Meinertz T, Baldus S (2005) Myeloperoxidase mediates neutrophil activation by association with CD11b/CD18 integrins. Proc Natl Acad Sci U S A 102(2):431–436. https://doi.org/10.1073/pnas.0405193102

Article  CAS  PubMed  Google Scholar 

Lee CW, Ren YJ, Marella M, Wang M, Hartke J, Couto SS (2020) Multiplex immunofluorescence staining and image analysis assay for diffuse large B cell lymphoma. J Immunol Methods 478:112714. https://doi.org/10.1016/j.jim.2019.112714

Article  CAS  PubMed  Google Scholar 

Lou H, Meng Y, Piao Y, Zhang N, Bachert C, Wang C, Zhang L (2016) Cellular phenotyping of chronic rhinosinusitis with nasal polyps. Rhinology 54(2):150–159. https://doi.org/10.4193/Rhino15.271

Article  PubMed  Google Scholar 

Mayumi M (1992) EoL-1, a human eosinophilic cell line. Leuk Lymphoma 7(3):243–250. https://doi.org/10.3109/10428199209053629

Article  CAS  PubMed  Google Scholar 

Opasawatchai A, Amornsupawat P, Jiravejchakul N, Chan-In W, Spoerk NJ, Manopwisedjaroen K, Singhasivanon P, Yingtaweesak T, Suraamornkul S, Mongkolsapaya J, Sakuntabhai A, Matangkasombut P, Loison F (2018) Neutrophil activation and early features of NET formation are associated with dengue virus infection in human. Front Immunol 9:3007. https://doi.org/10.3389/fimmu.2018.03007

Article  CAS  PubMed  Google Scholar 

Polzehl D, Moeller P, Riechelmann H, Perner S (2006) Distinct features of chronic rhinosinusitis with and without nasal polyps. Allergy 61(11):1275–1279. https://doi.org/10.1111/j.1398-9995.2006.01132.x

Article  CAS  PubMed  Google Scholar 

Pulli B, Ali M, Forghani R, Schob S, Hsieh KL, Wojtkiewicz G, Linnoila JJ, Chen JW (2013) Measuring myeloperoxidase activity in biological samples. PLoS ONE 8(7):e67976. https://doi.org/10.1371/journal.pone.0067976

Article  CAS  PubMed  PubMed Central  Google Scholar 

Rincon E, Rocha-Gregg BL, Collins SR (2018) A map of gene expression in neutrophil-like cell lines. BMC Genom 19(1):573. https://doi.org/10.1186/s12864-018-4957-6

Article  CAS  Google Scholar 

Schneider U, Schwenk HU, Bornkamm G (1977) Characterization of EBV-genome negative “null” and “T” cell lines derived from children with acute lymphoblastic leukemia and leukemic transformed non-Hodgkin lymphoma. Int J Cancer 19(5):621–626. https://doi.org/10.1002/ijc.2910190505

Article  CAS  PubMed  Google Scholar 

Snidvongs K, Lam M, Sacks R, Earls P, Kalish L, Phillips PS, Pratt E, Harvey RJ (2012) Structured histopathology profiling of chronic rhinosinusitis in routine practice. Int Forum Allergy Rhinol 2(5):376–385. https://doi.org/10.1002/alr.21032

Article  PubMed  Google Scholar 

Tomassen P, Vandeplas G, Van Zele T, Cardell LO, Arebro J, Olze H, Forster-Ruhrmann U, Kowalski ML, Olszewska-Ziaber A, Holtappels G, De Ruyck N, Wang X, Van Drunen C, Mullol J, Hellings P, Hox V, Toskala E, Scadding G, Lund V, Zhang L, Fokkens W, Bachert C (2016) Inflammatory endotypes of chronic rhinosinusitis based on cluster analysis of biomarkers. J Allergy Clin Immunol 137(5):1449–1456.e4. https://doi.org/10.1016/j.jaci.2015.12.1324

Article  CAS  PubMed  Google Scholar 

Topic RZ, Dodig S (2011) Eosinophil cationic protein–current concepts and controversies. Biochem Med (Zagreb) 21(2):111–121. https://doi.org/10.11613/bm.2011.019

Article  CAS  PubMed  Google Scholar 

Toro MDC, Antonio MA, Alves Dos Reis MG, de Assumpcao MS, Sakano E (2021) Achieving the best method to classify eosinophilic chronic rhinosinusitis: a systematic review. Rhinology 59(4):330–339. https://doi.org/10.4193/Rhin20.512

Article  CAS  PubMed  Google Scholar 

Van Zele T, Claeys S, Gevaert P, Van Maele G, Holtappels G, Van Cauwenberge P, Bachert C (2006) Differentiation of chronic sinus diseases by measurement of inflammatory mediators. Allergy 61(11):1280–1289. https://doi.org/10.1111/j.1398-9995.2006.01225.x

Article  CAS  PubMed