Role of Cytoskeletal Elements in Regulation of Synaptic Functions: Implications Toward Alzheimer’s Disease and Phytochemicals-Based Interventions

Agostinho P, Cunha RA, Oliveira C (2010) Neuroinflammation, oxidative stress and the pathogenesis of Alzheimer’s disease. Curr Pharm Des 16(25):2766–2778

Article  CAS  PubMed  Google Scholar 

Muñoz-Lasso DC, Romá-Mateo C, Pallardó FV, Gonzalez-Cabo P (2020) Much more than a scaffold: cytoskeletal proteins in neurological disorders. Cells 9(2):358

Article  PubMed  PubMed Central  Google Scholar 

Sept D (2007) Microtubule polymerization: one step at a time. CurrBiol 17:R764-766

CAS  Google Scholar 

Bamburg JR, Bernstein BW (2016) Actin dynamics and cofilin-actin rods in Alzheimer disease. Cytoskeleton 73(9):477–497

Article  CAS  PubMed  Google Scholar 

Walsh KP, Minamide LS, Kane SJ, Shaw AE, Brown DR, Pulford B, Bamburg JR (2014) Amyloid-β and proinflammatory cytokines utilize a prion protein-dependent pathway to activate NADPH oxidase and induce cofilin-actin rods in hippocampal neurons. PLoS ONE 9(4):e95995

Article  ADS  PubMed  PubMed Central  Google Scholar 

Boutajangout A, Sigurdsson EM, Krishnamurthy PK (2011) Tau as a therapeutic target for Alzheimer’s disease. Curr Alzheimer Res 8(6):666–677

Article  CAS  PubMed  PubMed Central  Google Scholar 

Didonna A, Opal P (2019) The role of neurofilament aggregation in neurodegeneration: lessons from rare inherited neurological disorders. Mol Neurodegener 14(1):1–10

Article  Google Scholar 

Rudrabhatla P, Jaffe H, Pant HC (2011) Direct evidence of phosphorylated neuronal intermediate filament proteins in neurofibrillary tangles (NFTs): phosphoproteomics of Alzheimer’s NFTs. FASEB J 25:3896–3905

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yao J, Hennessey T, Flynt A, Lai E, Beal MF, Lin MT (2010) MicroRNA-related cofilin abnormality in Alzheimer’s disease. PLoS ONE 5(12):e15546

Article  ADS  CAS  PubMed  PubMed Central  Google Scholar 

Walsh DM, Selkoe DJ (2004) Deciphering the molecular basis of memory failure in Alzheimer’s disease. Neuron 44(1):181–193

Article  CAS  PubMed  Google Scholar 

Masliah E, Mallory M, Alford M, DeTeresa R, Hansen LA, McKeel DW, Morris JC (2001) Altered expression of synaptic proteins occurs early during progression of Alzheimer’s disease. Neurology 56(1):127–129

Article  CAS  PubMed  Google Scholar 

Parajuli LK, Tanaka S, Okabe S (2017) Insights into age-old questions of new dendritic spines: from form to function. Brain Res Bull 129:3–11

Article  PubMed  Google Scholar 

Vargas-Restrepo F, Sabogal-Guáqueta AM, Cardona-Gómez GP (2018) Quercetin ameliorates inflammation in CA1 hippocampal region in aged triple transgenic Alzheimer´ s disease mice model. Biomedica 38:62–69

Google Scholar 

O’Neil SD, Rácz B, Brown WE, Gao Y, Soderblom EJ, Yasuda R, Soderling SH (2021) Action potential-coupled Rho GTPase signaling drives presynaptic plasticity. Elife 10:e63756

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhang C, Rasband MN (2016) Cytoskeletal control of axon domain assembly and function. Curr Opin Neurobiol 39:116–121

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bucher M, Fanutza T, Mikhaylova M (2020) Cytoskeletal makeup of the synapse: shaft versus spine. Cytoskeleton 77(3–4):55–64

Article  CAS  PubMed  Google Scholar 

Goldman JE, Yen SH (1986) Cytoskeletal protein abnormalities in neurodegenerative diseases. Ann Neurol 19:209–223

Article  CAS  PubMed  Google Scholar 

Kaur P, Sharma S (2018) Recent advances in pathophysiology of traumatic brain injury. Curr Neuropharmacol 16:1224–1238

Article  CAS  PubMed  PubMed Central  Google Scholar 

Medeiros R, Baglietto VD, LaFerla FM (2011) The role of tau in Alzheimer’s disease and related disorders. CNS NeurosciTher 17:514–524

Article  CAS  Google Scholar 

Galloway PG, Mulvihill P, Perry G (1992) Filaments of Lewy bodies contain insoluble cytoskeletal elements. Am J Pathol 140:809–822

CAS  PubMed  PubMed Central  Google Scholar 

Cartier L, Galvez S, Gajdusek DC (1985) Familial clustering of the ataxic form of Creutzfeldt-Jakob disease with Hirano bodies. J Neurol Neurosurg Psychiatry 48:2348

Article  Google Scholar 

Klymkowsky MW, Plummer DJ (1985) Giant axonal neuropathy: a conditional mutation affecting cytoskeletal organization. J Cell Biol 100:245–250

Article  CAS  PubMed  Google Scholar 

Karima O, Riazi G, Yousefi R, Movahedi AAM (2010) The enhancement effect of beta-boswellic acid on hippocampal neurites outgrowth and branching (an in vitro study). Neurol Sci 31(3):315–320

Article  PubMed  Google Scholar 

Promsuban C, Limsuvan S, Akarasereenont P, Tilokskulchai K, Tapechum S, Pakaprot N (2017) Bacopa monnieri extract enhances learning-dependent hippocampal long-term synaptic potentiation. NeuroReport 28(16):1031–1035

Article  PubMed  Google Scholar 

Bourne JN, Harris KM (2011) Coordination of size and number of excitatory and inhibitory synapses results in a balanced structural plasticity along mature hippocampal CA1 dendrites during LTP. Hippocampus 21(4):354–373

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hruska M, Henderson N, Le Marchand SJ, Jafri H, Dalva MB (2018) Synaptic nanomodules underlie the organization and plasticity of spine synapses. Nat Neurosci 21(5):671–682

Article  CAS  PubMed  PubMed Central  Google Scholar 

MacGillavry HD, Song Y, Raghavachari S, Blanpied TA (2013) Nanoscale scaffolding domains within the postsynaptic density concentrate synaptic AMPA receptors. Neuron 78(4):615–622

Article  CAS  PubMed  PubMed Central  Google Scholar 

MacGillavry HD, Kerr JM, Kassner J, Frost NA, Blanpied TA (2016) Shank-cortactin interactions control actin dynamics to maintain flexibility of neuronal spines and synapses. Eur J Neurosci 43(2):179–193

Article  PubMed  Google Scholar 

Matt L, Kim K, Hergarden AC, Patriarchi T, Malik ZA, Park DK, Chowdhury D, Buonarati OR, Henderson PB, Gökçek Saraç Ç, Zhang Y, Mohapatra D, Horne MC, Ames JB, Hell JW (2018) Α-actinin anchors PSD-95 at postsynaptic sites. Neuron 97(5):1094-1109.e9

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bär J, Kobler O, van Bommel B, Mikhaylova M (2016) Periodic F-actin structures shape the neck of dendritic spines. Sci Rep 6:37136

Article  ADS  PubMed  PubMed Central  Google Scholar 

Mikhaylova M, Bär J, van Bommel B, Schätzle P, YuanXiang P, Raman R, Hradsky J, Konietzny A, Loktionov EY, Reddy PP, Lopez-Rojas J, Spilker C, Kobler O, Raza SA, Stork O, Hoogenraad CC, Kreutz MR (2018) Caldendrin directly couples postsynaptic calcium signals to actin remodeling in dendritic spines. Neuron 97(5):1110-1125.e14

Article  CAS  PubMed  Google Scholar 

He Y, Janssen WG, Vissavajjhala P, Morrison JH (1998) Synaptic distribution of GluR2 in hippocampal GABAergic interneurons and pyramidal cells: a double-label immunogold analysis. Exp Neurol 150(1):1–13

Article  CAS  PubMed  Google Scholar 

Konietzny A, González-Gallego J, Bar J, Perez-Alvarez A, Drakew A, Demmers JA, Mikhaylova M (2019) Myosin V regulates synaptopodin clustering and localization in the dendrites of hippocampal neurons. J Cell Sci 132(16):jcs230177

Article  CAS  PubMed  PubMed Central  Google Scholar 

Crosby KC, Gookin SE, Garcia JD, Hahm KM, Dell’Acqua ML, Smith KR (2019) Nanoscale subsynaptic domains underlie the organization of the inhibitory synapse. Cell Rep 26(12):3284-3297.e3

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sheng M, Kim E (2011) The postsynaptic organization of synapses. Cold Spring Harb Perspect Biol 3(12):a005678

Article  PubMed  PubMed Central  Google Scholar 

Giesemann T, Schwarz G, Nawrotzki R, Berhörster K, Rothkegel M, Schlüter K, Schrader N, Schindelin H, Mendel RR, Kirsch J, Jockusch BM (2003) Complex formation between the postsynaptic scaffolding protein gephyrin, profilin, and Mena: a possible link to the microfilament system. J Neurosci 23(23):8330–8339

Article  CAS  PubMed  PubMed Central  Google Scholar 

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