Stoll, B. J. et al. Trends in care practices, morbidity, and mortality of extremely preterm neonates, 1993–2012. JAMA 314, 1039–1051 (2015).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Papillon, S., Castle, S. L., Gayer, C. P. & Ford, H. R. Necrotizing enterocolitis: contemporary management and outcomes. Adv. Pediatr. 60, 263–279 (2013).

Article  PubMed  Google Scholar 

Stey, A. et al. Outcomes and costs of surgical treatments of necrotizing enterocolitis. Pediatrics 135, e1190–e1197 (2015).

Article  PubMed  PubMed Central  Google Scholar 

Zhang, Y. et al. Necrotizing enterocolitis requiring surgery: outcomes by intestinal location of disease in 4371 infants. J. Pediatr. Surg. 46, 1475–1481 (2011).

Article  PubMed  Google Scholar 

Fitzgibbons, S. C. et al. Mortality of necrotizing enterocolitis expressed by birth weight categories. J. Pediatr. Surg. 44, 1072–1075 (2009). discussion 1075-1076.

Article  PubMed  Google Scholar 

Robinson, J. R. et al. Surgical necrotizing enterocolitis. Semin Perinatol. 41, 70–79 (2017).

Article  PubMed  Google Scholar 

Hintz, S. R. et al. Neurodevelopmental and growth outcomes of extremely low birth weight infants after necrotizing enterocolitis. Pediatrics 115, 696–703 (2005).

Article  PubMed  Google Scholar 

Garzoni, L., Faure, C. & Frasch, M. G. Fetal cholinergic anti-inflammatory pathway and necrotizing enterocolitis: the brain-gut connection begins in utero. Front. Integr. Neurosci. 7, 57 (2013).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bisquera, J. A., Cooper, T. R. & Berseth, C. L. Impact of necrotizing enterocolitis on length of stay and hospital charges in very low birth weight infants. Pediatrics 109, 423–428 (2002).

Article  PubMed  Google Scholar 

Lin, P. W. & Stoll, B. J. Necrotising enterocolitis. Lancet 368, 1271–1283 (2006).

Article  PubMed  Google Scholar 

Wendel, G. D. Jr. et al. Identification of Treponema pallidum in amniotic fluid and fetal blood from pregnancies complicated by congenital syphilis. Obstet. Gynecol. 78, 890–895 (1991).

PubMed  Google Scholar 

Morgan-Capner, P., Rodeck, C. H., Nicolaides, K. H. & Cradock-Watson, J. E. Prenatal detection of rubella-specific IgM in fetal sera. Prenat. Diagn. 5, 21–26 (1985).

Article  CAS  PubMed  Google Scholar 

Thilaganathan, B., Carroll, S. G., Plachouras, N., Makrydimas, G. & Nicolaides, K. H. Fetal immunological and haematological changes in intrauterine infection. Br. J. Obstet. Gynaecol. 101, 418–421 (1994).

Article  CAS  PubMed  Google Scholar 

Donders, G. G., Moerman, P., Caudron, J. & Van Assche, F. A. Intra-uterine Candida infection: a report of four infected fetusses from two mothers. Eur. J. Obstet. Gynecol. Reprod. Biol. 38, 233–238 (1991).

Article  CAS  PubMed  Google Scholar 

Carroll, S. G. & Nicolaides, K. H. Fetal haematological response to intra-uterine infection in preterm prelabour amniorrhexis. Fetal Diagn. Ther. 10, 279–285 (1995).

Article  CAS  PubMed  Google Scholar 

Abrams, E. T. et al. Malaria during pregnancy and foetal haematological status in Blantyre, Malawi. Malar. J. 4, 39 (2005).

Article  PubMed  PubMed Central  Google Scholar 

Gomez, R. et al. The fetal inflammatory response syndrome. Am. J. Obstet. Gynecol. 179, 194–202 (1998).

Article  CAS  PubMed  Google Scholar 

Yoon, B. H. et al. The relationship among inflammatory lesions of the umbilical cord (funisitis), umbilical cord plasma interleukin 6 concentration, amniotic fluid infection, and neonatal sepsis. Am. J. Obstet. Gynecol. 183, 1124–1129 (2000).

Article  CAS  PubMed  Google Scholar 

Kim, C. J., Yoon, B. H., Park, S. S., Kim, M. H. & Chi, J. G. Acute funisitis of preterm but not term placentas is associated with severe fetal inflammatory response. Hum. Pathol. 32, 623–629 (2001).

Article  CAS  PubMed  Google Scholar 

Pacora, P. et al. Funisitis and chorionic vasculitis: the histological counterpart of the fetal inflammatory response syndrome. J. Matern. Fetal Neonatal Med. 11, 18–25 (2002).

Article  CAS  PubMed  Google Scholar 

Oh, J. W., Park, C. W., Moon, K. C., Park, J. S. & Jun, J. K. The relationship among the progression of inflammation in umbilical cord, fetal inflammatory response, early-onset neonatal sepsis, and chorioamnionitis. PLoS One 14, e0225328 (2019).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Been, J. V. et al. Histologic chorioamnionitis, fetal involvement, and antenatal steroids: effects on neonatal outcome in preterm infants. Am. J. Obstet. Gynecol. 201, 587 (2009). e581-588.

Article  Google Scholar 

Elimian, A. et al. Histologic chorioamnionitis, antenatal steroids, and perinatal outcomes. Obstet. Gynecol. 96, 333–336 (2000).

CAS  PubMed  Google Scholar 

Lau, J. et al. Chorioamnionitis with a fetal inflammatory response is associated with higher neonatal mortality, morbidity, and resource use than chorioamnionitis displaying a maternal inflammatory response only. Am. J. Obstet. Gynecol. 193, 708–713 (2005).

Article  PubMed  Google Scholar 

Goldenberg, R. L. et al. The Alabama preterm birth study: corticosteroids and neonatal outcomes in 23- to 32-week newborns with various markers of intrauterine infection. Am. J. Obstet. Gynecol. 195, 1020–1024 (2006).

Article  CAS  PubMed  Google Scholar 

Ogunyemi, D., Murillo, M., Jackson, U., Hunter, N. & Alperson, B. The relationship between placental histopathology findings and perinatal outcome in preterm infants. J. Matern. Fetal Neonatal. Med. 13, 102–109 (2003).

Article  CAS  PubMed  Google Scholar 

Been, J. V., Lievense, S., Zimmermann, L. J., Kramer, B. W. & Wolfs, T. G. Chorioamnionitis as a risk factor for necrotizing enterocolitis: a systematic review and meta-analysis. J. Pediatr. 162, 236–242 e232 (2013).

Article  PubMed  Google Scholar 

Neu, J. & Walker, W. A. Necrotizing enterocolitis. N. Engl. J. Med. 364, 255–264 (2011).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Andrews, R. E. & Coe, K. L. Clinical presentation and multifactorial pathogenesis of necrotizing enterocolitis in the preterm infant. Adv. Neonatal Care 21, 349–355 (2021).

Article  PubMed  Google Scholar 

Duric, B. et al. Effect of time of diagnosis to surgery on outcome, including long-term neurodevelopmental outcome, in necrotizing enterocolitis. Pediatr. Surg. Int. 39, 2 (2022).

Article  PubMed  PubMed Central  Google Scholar 

Greer, L. G. et al. An immunologic basis for placental insufficiency in fetal growth restriction. Am. J. Perinatol. 29, 533–538 (2012).

PubMed  Google Scholar 

Mir, I. N. et al. Placental pathology is associated with severity of neonatal encephalopathy and adverse developmental outcomes following hypothermia. Am. J. Obstet. Gynecol. 213, 849 (2015). e841-847.

Article  Google Scholar 

Redline, R. W. & Abramowsky, C. R. Clinical and pathologic aspects of recurrent placental villitis. Hum. Pathol. 16, 727–731 (1985).

Article  CAS  PubMed  Google Scholar 

Redline, R. W., Heller, D., Keating, S. & Kingdom, J. Placental diagnostic criteria and clinical correlation-a workshop report. Placenta 26, S114–S117 (2005).

Article  PubMed  Google Scholar 

Khong, T. Y. et al. Sampling and definitions of placental lesions: Amsterdam placental workshop group consensus statement. Arch. Pathol. Lab Med 140, 698–713 (2016).

Article  PubMed  Google Scholar 

Olsen, I. E., Groveman, S. A., Lawson, M. L., Clark, R. H. & Zemel, B. S. New intrauterine growth curves based on United States data. Pediatrics 125, e214–e224 (2010).

Article  PubMed  Google Scholar 

Olsen, I. E. et al. BMI curves for preterm infants. Pediatrics 135, e572–581, (2015).

Article  PubMed  Google Scholar 

Andrews, W. W. et al. The Alabama Preterm Birth study: polymorphonuclear and mononuclear cell placental infiltrations, other markers of inflammation, and outcomes in 23- to 32-week preterm newborn infants. Am. J. Obstet. Gynecol. 195, 803–808 (2006).

Article  CAS  PubMed  Google Scholar 

Garg, P. M. et al. Association of placental pathologic findings with the severity of necrotizing enterocolitis in preterm infants—a matched case-control study. Fetal Pediatr. Pathol. 42, 187–197 (2023).

Article  PubMed  Google Scholar 

Neu, J., Mshvildadze, M. & Mai, V. A roadmap for understanding and preventing necrotizing enterocolitis. Curr. Gastroenterol. Rep. 10, 450–457 (2008).

Article  PubMed