Adiga MS, Chandy S, Ramachandra N, Appaji L, Kumari BA, Ramaswamy G, Savithri HS, Krishnamoorthy L. Methylenetetrahydrofolate reductase gene polymorphisms and risk of acute lymphoblastic leukemia in children. Indian J Cancer. 2010;47(1):40.

Article  Google Scholar 

Agha A, Shabaan H, Abdel-Gawad E, El-Ghannam D. Polymorphism of CYP1A1 gene and susceptibility to childhood acute lymphoblastic leukemia in Egypt. Leuk Lymphoma. 2014;55(3):618–23.

Article  CAS  PubMed  Google Scholar 

Al-Achkar W, Azeiz G, Moassass F, Wafa A. Influence of CYP1A1, GST polymorphisms and susceptibility risk of chronic myeloid leukemia in Syrian population. Med Oncol. 2014;31(5):889.

Article  PubMed  Google Scholar 

Aly RM, Taalab MM, Ghazy HF. MTHFR A1298C and C677T gene polymorphisms and susceptibility to chronic myeloid leukemia in Egypt. Int J Clin Exp Pathol. 2014;7(5):2571.

CAS  PubMed  PubMed Central  Google Scholar 

Azhar MR, Rahimi Z, Vaisi-Raygani A, Akramipour R, Madani H, Rahimi Z, Parsian A. Lack of association between MTHFR C677T and A1298C polymorphisms and risk of childhood acute lymphoblastic leukemia in the Kurdish population from Western Iran. Genet Test Mol Biomark. 2012;16(3):198–202.

Article  CAS  Google Scholar 

Bhatt TA, Mir MR, Qasim I, Misra SS, Kirmani MA. Genetic polymorphism of 5, 10 Methylenetetrahdrofolatereducatse C677T in Kashmir population. Biotechnology. 2008;1:1–4.

Google Scholar 

Bhattacharjee P, Paul S, Banerjee M, Patra D, Banerjee P, Ghoshal N, Bandyopadhyay A, Giri AK. Functional compensation of glutathione S-transferase M1 (GSTM1) null by another GST superfamily member, GSTM2. Sci Rep. 2013;3:2704. https://doi.org/10.1038/srep02704.

Article  PubMed  PubMed Central  Google Scholar 

Brustolin S, Giugliani R, Félix TM. Genetics of homocysteine metabolism and associated disorders. Braz J Med Biol Res Rev Pesqui Biol. 2010;43(1):1–7. https://doi.org/10.1590/s0100-879x2009007500021.

Article  CAS  Google Scholar 

Bănescu C, Trifa AP, Voidăzan S, Moldovan VG, Macarie I, Benedek Lazar E, Dima D, Duicu C, Dobreanu M. CAT, GPX1, MnSOD, GSTM1, GSTT1, and GSTP1 genetic polymorphisms in chronic myeloid leukemia: a case-control study. Oxid Med Cell Longev. 2014;2014: 875861. https://doi.org/10.1155/2014/875861.

Article  PubMed  PubMed Central  Google Scholar 

Chen HC, Hu WX, Liu QX, Li WK, Chen FZ, Rao ZZ, Liu XF, Luo YP, Cao YF. Genetic polymorphisms of metabolic enzymes CYP1A1, CYP2D6, GSTM1 and GSTT1 and leukemia susceptibility. Eur J Cancer Prev Off J Eur Cancer Prev Organ (ECP). 2008;17(3):251–8. https://doi.org/10.1097/CEJ.0b013e3282b72093.

Article  CAS  Google Scholar 

Chen CL, Liu Q, Pui CH, Rivera GK, Sandlund JT, Ribeiro R, Evans WE, Relling MV. Higher frequency of glutathione S-transferase deletions in black children with acute lymphoblastic leukemia. Blood. 1997;89(5):1701–7.

Article  CAS  PubMed  Google Scholar 

Devi AR, Govindaiah V, Ramakrishna G, Naushad SM. Prevalence of methylene tetrahydrofolate reductase polymorphism in South Indian population. Curr Sci. 2004;10:440–3.

Google Scholar 

Diab NA, Elderdery AY, Mills J, Khalil HB. The role of genetic polymorphisms of the MTHFR (C677T and A1298C) gene in the incidence of acute myeloid leukaemia. Pak J Med Health Sci. 2019;13(4):1330–4.

Google Scholar 

Genc A, Atalay T, Gedikoglu G, Zulfikar B, Kullu S. Leukemic children: clinical and histopathological gingival lesions. J Clin Pediatr Dent. 1998;22(3):253–6.

CAS  PubMed  Google Scholar 

Gra OA, Glotov AS, Kozhekbaeva ZhM, Makarova OV, Nasedkina TV. Genetic polymor-phism of GST, NAT2, and MTRR and susceptibilityto childhood acute leukemia. Mol Biol (Mosk) 2008;42(2):187–97.

Article  Google Scholar 

Guven M, Unal S, Erhan D, Ozdemir N, Baris S, Celkan T, Bostancı M, Batar B. Role of glutathione S-transferase M1, T1 and P1 gene polymorphisms in childhood acute lymphoblastic leukemia susceptibility in a Turkish population. Meta gene. 2015;5:115–9. https://doi.org/10.1016/j.mgene.2015.06.002.

Article  PubMed  PubMed Central  Google Scholar 

Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell. 2011;144(5):646–74.

Article  CAS  PubMed  Google Scholar 

Haranatha RP, Jamil K. Polymorphisms in the GST (M1 andT1) gene and their possible association with susceptibility to childhood acute lymphocytic leukemia in Indian population. Afr J Biotechnol. 2006;5(16):1454–6.

CAS  Google Scholar 

He XF, Wei W, Liu ZZ, Shen XL, Yang XB, Wang SL, Xie DL. Association between the CYP1A1 T3801C polymorphism and risk of cancer: evidence from 268 case–control studies. Gene. 2014;534(2):324–44.

Article  CAS  PubMed  Google Scholar 

Huang L, Deng D, Peng Z, Ye F, Xiao Q, Zhang B, Ye B, Mo Z, Yang X, Liu Z. Polymorphisms in the methylenetetrahydrofolate reductase gene (MTHFR) are associated with susceptibility to adult acute myeloid leukemia in a Chinese population. Cancer Epidemiol. 2015;39(3):328–33.

Article  PubMed  Google Scholar 

Idris HM, Elderdery AY, Khalil HB, Mills J. Genetic polymorphism of GSTP1, GSTM1 and GSTT1 genes and susceptibility to chronic myeloid leukaemia. Asian Pac J Cancer Prev APJCP. 2020;21(2):499–503. https://doi.org/10.31557/APJCP.2020.21.2.499.

Article  CAS  PubMed  Google Scholar 

Jakovljevic K, Malisic E, Cavic M, Radulovic S, Jankovic R. Association between methylenetetrahydrofolate reductase polymorphism C677T and risk of chronic myeloid leukemia in Serbian population. Leuk Lymphoma. 2012;53(7):1327–30.

Article  CAS  PubMed  Google Scholar 

Joseph T, Kusumakumary P, Chacko P, Abraham A, Radhakrishna Pillai M. Genetic polymorphism of CYP1A1, CYP2D6, GSTM1 and GSTT1 and susceptibility to acute lymphoblastic leukaemia in Indian children. Pediatr Blood Cancer. 2004;43(5):560–7. https://doi.org/10.1002/pbc.20074.

Article  PubMed  Google Scholar 

Karkucak M, Yakut T, Gulten T, Ali R. Investigation of GSTP1 (Ile105Val) gene polymorphism in chronic myeloid leukaemia patients. Int J Hum Genet. 2012;12(3):145–9.

Article  CAS  Google Scholar 

Ketterer B. Protective role of glutathione and glutathione transferases in mutagenesis and carcinogenesis. Mutat Res. 1988;202(2):343–61. https://doi.org/10.1016/0027-5107(88)90197-2.

Article  CAS  PubMed  Google Scholar 

Krajinovic M, Labuda D, Richer C, Karimi S, Sinnett D. Susceptibility to childhood acute lymphoblastic leukemia: influence of CYP1A1, CYP2D6, GSTM1, and GSTT1 genetic polymorphisms. Blood. 1999;93(5):1496–501.

Article  CAS  PubMed  Google Scholar 

Kreile M, Rots D, Piekuse L, Cebura E, Grutupa M, Kovalova Z, Lace B. Lack of association between polymorphisms in genes MTHFR and MDR1 with risk of childhood acute lymphoblastic leukemia. Asian Pac J Cancer Prev. 2014;15(22):9707–11.

Article  PubMed  Google Scholar 

Lakkireddy S, Aula S, Swamy AV, Kapley A, Digumarti RR, Jamil K. Association of the common CYP1A1* 2C variant (Ile462Val polymorphism) with chronic myeloid leukemia (CML) in patients undergoing imatinib therapy. Cell J (Yakhteh). 2015;17(3):510.

Google Scholar 

Leclerc D, Rozen R. Génétiquemoléculaire de MTHFR: les polymorphismes ne sont pas tousbénins [molecular genetics of MTHFR: polymorphisms are not all benign]. Medecinesciences: M/S. 2007;23(3):297–302. https://doi.org/10.1051/medsci/2007233297.

Article  Google Scholar 

Lee KM, Ward MH, Han S, Ahn HS, Kang HJ, Choi HS, Shin HY, Koo HH, Seo JJ, Choi JE, Yo A. Paternal smoking, genetic polymorphisms in CYP1A1 and childhood leukemia risk. Leuk Res. 2009;33(2):250–8.

Article  CAS  PubMed  Google Scholar 

Lopez-Lopez E, Gutierrez-Camino A, Bilbao-Aldaiturriaga N, Pombar-Gomez M, Martin-Guerrero I, Garcia-Orad A. Pharmacogenetics of childhood acute lymphoblastic leukemia. Pharmacogenomics. 2014;15(10):1383–98.

Article  CAS  PubMed  Google Scholar 

Mahmoud LB, Mdhaffar M, Frikha R, Ghozzi H, Hakim A, Sahnoun Z, Elloumi M, Zeghal K. Use of MTHFR C677T polymorphism and plasma pharmacokinetics to predict methotrexate toxicity in patients with acute lymphoblastic leukemia. Adv Clin Exp Med Off Organ Wroclaw Med Univ. 2018;27(8):1061–8.

Article  Google Scholar 

Majumdar S, Mondal BC, Ghosh M, Dey S, Mukhopadhyay A, Chandra S, Dasgupta UB. Association of cytochrome P450, glutathione S-transferase and N-acetyl transferase 2 gene polymorphisms with incidence of acute myeloid leukemia. Eur J Cancer Prev Off J Eur Cancer Prev Organ (ECP). 2008;17(2):125–32. https://doi.org/10.1097/CEJ.0b013e3282b6fd68.

Article  CAS  Google Scholar 

Miranda-Filho A, Piñeros M, Ferlay J, Soerjomataram I, Monnereau A, Bray F. Epidemiological patterns of leukaemia in 184 countries: a population-based study. Lancet Haematol. 2017;5(1):e14–24.

Article  Google Scholar 

Moulik NR, Parveen F, Kumar A, Agrawal S. Glutathione-S-transferase polymorphism and acute lymphoblastic leukemia (ALL) in north Indian children: a case-control study and meta-analysis. J Hum Genet. 2014;59(9):529–35. https://doi.org/10.1038/jhg.2014.66.

Article  CAS  PubMed  Google Scholar 

Mukherjee M, Joshi S, Bagadi S, Dalvi M, Rao A, Shetty KR. A low prevalence of the C677T mutation in the methylenetetrahydrofolate reductase gene in Asian Indians. Clin Genet. 2002;61:155–9.

Article  CAS  PubMed  Google Scholar 

Nida S, Bhat J, Masood A, Shah I, Wani A, Ganai BA. Gene variants of CYP1A1 and CYP2D6 and the risk of childhood acute lymphoblastic leukaemia; outcome of a case control study from Kashmir, India. Mol Biol Res Commun. 2017;6(2):77–84.

CAS  PubMed  PubMed Central  Google Scholar 

Oh D, Kim NK, Jang MJ, Kim HC, Lee JH, Lee JA, Ahn MJ, Kim CS, Kim HS, Park S, Chi HS, Min YH, HOGS INVESTIGATORS. Association of the 5, 10-methylenetetrahydrofolate reductase (MTHFR C677T and A1298C) polymorphisms in Korean patients with adult acute lymphoblastic leukemia. Anticancer Res. 2007;27(5A):3419–24.

CAS  PubMed