Abelson Helper Integration Site 1 haplotypes and peripheral blood expression associates with lithium response and immunomodulation in bipolar patients

Adams WK, Levesque DL, Cocker PJ et al (2020) Decreased motor impulsivity following chronic lithium treatment in male rats is associated with reduced levels of pro-inflammatory cytokines in the orbitofrontal cortex. Brain Behav Immun 89:339–349. https://doi.org/10.1016/j.bbi.2020.07.018

Article  CAS  Google Scholar 

Alcocer-Gómez E, de Miguel M, Casas-Barquero N et al (2014) NLRP3 inflammasome is activated in mononuclear blood cells from patients with major depressive disorder. Brain Behav Immun 36:111–117. https://doi.org/10.1016/j.bbi.2013.10.017

Article  CAS  Google Scholar 

Alcocer-Gómez E, Casas-Barquero N, Williams MR et al (2017) Antidepressants induce autophagy dependent-NLRP3-inflammasome inhibition in major depressive disorder. Pharmacol Res 121:114–121. https://doi.org/10.1016/J.PHRS.2017.04.028

Article  Google Scholar 

Alvarez Retuerto AI, Cantor RM, Gleeson JG et al (2008) Association of common variants in the Joubert syndrome gene (AHI1) with autism. Hum Mol Genet 17:3887–3896. https://doi.org/10.1093/HMG/DDN291

Article  CAS  PubMed Central  Google Scholar 

Amann-Zalcenstein D, Avidan N, Kanyas K et al (2006) (2006) AHI1, a pivotal neurodevelopmental gene, and C6orf217 are associated with susceptibility to schizophrenia. Eur J Hum Genet 1410(14):1111–1119. https://doi.org/10.1038/sj.ejhg.5201675

Article  CAS  Google Scholar 

Barbisan F, Azzolin VF, Teixeira CF, et al (2017) Xanthine-catechin mixture enhances lithium-induced anti-inflammatory response in activated macrophages in vitro. Biomed Res Int 2017. https://doi.org/10.1155/2017/4151594

Brambilla P, Bellani M, Isola M et al (2014) Increased M1/decreased M2 signature and signs of Th1/Th2 shift in chronic patients with bipolar disorder, but not in those with schizophrenia. Transl Psychiatry 4:e406–e406. https://doi.org/10.1038/tp.2014.46

Article  CAS  PubMed Central  Google Scholar 

Cade JF (1949) Lithium salts in the treatment of psychotic excitement. Med J Aust 2:349–352. https://doi.org/10.1080/j.1440-1614.1999.06241.x

Article  CAS  Google Scholar 

Carvalho AF, Firth J, Vieta E (2020) Bipolar disorder. N Engl J Med 383:58–66. https://doi.org/10.1056/NEJMRA1906193

Article  CAS  Google Scholar 

Chen CJ, Kono H, Golenbock D et al (2007) Identification of a key pathway required for the sterile inflammatory response triggered by dying cells. Nat Med 13:851–856. https://doi.org/10.1038/NM1603

Article  CAS  Google Scholar 

Chou YH, Hsieh WC, Chen LC et al (2016) Association between the serotonin transporter and cytokines: implications for the pathophysiology of bipolar disorder. J Affect Disord 191:29–35. https://doi.org/10.1016/J.JAD.2015.10.056

Article  CAS  Google Scholar 

Corponi F, Bonassi S, Vieta E et al (2019) Genetic basis of psychopathological dimensions shared between schizophrenia and bipolar disorder. Prog Neuro-Psychopharmacol Biol Psychiatry 89:23–29. https://doi.org/10.1016/J.PNPBP.2018.08.023

Article  Google Scholar 

de Baumont A, Maschietto M, Lima L et al (2015) Innate immune response is differentially dysregulated between bipolar disease and schizophrenia. Schizophr Res 161:215–221. https://doi.org/10.1016/J.SCHRES.2014.10.055

Article  Google Scholar 

Di Paolo NC, Shayakhmetov DM (2016) Interleukin 1α and the inflammatory process. Nat Immunol 17:906–913. https://doi.org/10.1038/NI.3503

Article  PubMed Central  Google Scholar 

Dixon-Salazar T, Silhavy JL, Marsh SE et al (2004) Mutations in the AHI1 gene, encoding jouberin, cause Joubert syndrome with cortical polymicrogyria. Am J Hum Genet 75:979–987. https://doi.org/10.1086/425985

Article  CAS  PubMed Central  Google Scholar 

Dong H, Zhang X, Dai X et al (2014) Lithium ameliorates lipopolysaccharide-induced microglial activation via inhibition of toll-like receptor 4 expression by activating the PI3K/Akt/FoxO1 pathway. J Neuroinflammation 11:140. https://doi.org/10.1186/s12974-014-0140-4

Article  CAS  PubMed Central  Google Scholar 

Elliott EI, Sutterwala FS (2015) Initiation and perpetuation of NLRP3 inflammasome activation and assembly. Immunol Rev 265:35–52. https://doi.org/10.1111/IMR.12286

Article  CAS  PubMed Central  Google Scholar 

Fries GR, Walss-Bass C, Bauer ME, Teixeira AL (2019) Revisiting inflammation in bipolar disorder. Pharmacol Biochem Behav 177:12–19. https://doi.org/10.1016/j.pbb.2018.12.006

Article  CAS  Google Scholar 

Groß O, Yazdi AS, Thomas CJ et al (2012) Inflammasome activators induce interleukin-1α secretion via distinct pathways with differential requirement for the protease function of caspase-1. Immunity 36:388–400. https://doi.org/10.1016/J.IMMUNI.2012.01.018

Article  Google Scholar 

He Y, Hara H, Núñez G (2016) Mechanism and regulation of NLRP3 inflammasome activation. Trends Biochem Sci 41:1012–1021. https://doi.org/10.1016/J.TIBS.2016.09.002

Article  CAS  PubMed Central  Google Scholar 

Himmerich H, Bartsch S, Hamer H et al (2014) Modulation of cytokine production by drugs with antiepileptic or mood stabilizer properties in anti-CD3- and anti-Cd40-stimulated blood in vitro. Oxid Med Cell Longev 2014. https://doi.org/10.1155/2014/806162

Hung Y-Y, Huang K-W, Kang H-Y et al (2016) Antidepressants normalize elevated Toll-like receptor profile in major depressive disorder. Psychopharmacology 233:1707–1714. https://doi.org/10.1007/s00213-015-4087-7

Article  CAS  Google Scholar 

Ingason A, Sigmundsson T, Steinberg S et al (2007) Support for involvement of the AHI1 locus in schizophrenia. Eur J Hum Genet 15:988–991. https://doi.org/10.1038/SJ.EJHG.5201848

Article  CAS  Google Scholar 

Ingason A, Giegling I, Cichon S et al (2010) A large replication study and meta-analysis in European samples provides further support for association of AHI1 markers with schizophrenia. Hum Mol Genet 19:1379–1386. https://doi.org/10.1093/HMG/DDQ009

Article  CAS  PubMed Central  Google Scholar 

Jones SA, Jenkins BJ (2018) Recent insights into targeting the IL-6 cytokine family in inflammatory diseases and cancer. Nat Rev Immunol 18:773–789

Article  CAS  Google Scholar 

Kanneganti TD (2015) The inflammasome: firing up innate immunity. Immunol Rev 265:1–5. https://doi.org/10.1111/imr.12297

Article  CAS  PubMed Central  Google Scholar 

Khan MS, Ali T, Abid MN et al (2017) Lithium ameliorates lipopolysaccharide-induced neurotoxicity in the cortex and hippocampus of the adult rat brain. Neurochem Int 108:343–354. https://doi.org/10.1016/J.NEUINT.2017.05.008

Article  CAS  Google Scholar 

Kim HK, Andreazza AC, Elmi N et al (2016) Nod-like receptor pyrin containing 3 (NLRP3) in the post-mortem frontal cortex from patients with bipolar disorder: a potential mediator between mitochondria and immune-activation. J Psychiatr Res 72:43–50 https://doi.org/10.1016/j.jpsychires.2015.10.015

Knijff EM, Nadine BM, Kupka RW et al (2007) An imbalance in the production of IL-1β and IL-6 by monocytes of bipolar patients: restoration by lithium treatment. Bipolar Disord 9:743–753. https://doi.org/10.1111/j.1399-5618.2007.00444.x

Article  CAS  Google Scholar 

Lancaster MA, Gopal DJ, Kim J et al (2011) Defective Wnt-dependent cerebellar midline fusion in a mouse model of Joubert syndrome. Nat Med 17:726–731. https://doi.org/10.1038/nm.2380

Article  CAS  PubMed Central  Google Scholar 

Landén M, Larsson H, Lichtenstein P et al (2021) Respiratory infections during lithium and valproate medication: a within-individual prospective study of 50,000 patients with bipolar disorder. Int J Bipolar Disord 9:4. https://doi.org/10.1186/s40345-020-00208-y

Article  CAS  PubMed Central  Google Scholar 

Le Clerc S, Lombardi L, Baune BT et al (2021) HLA-DRB1 and HLA-DQB1 genetic diversity modulates response to lithium in bipolar affective disorders. Sci Rep 11:70. https://doi.org/10.1038/S41598-021-97140-7

Article  Google Scholar 

Lesh TA, Careaga M, Rose DR et al (2018) Cytokine alterations in first-episode schizophrenia and bipolar disorder: relationships to brain structure and symptoms. J Neuroinflammation 15. https://doi.org/10.1186/S12974-018-1197-2

Leu SJ, Yang YY, Liu HC et al (2017) Valproic acid and lithium meditate anti-inflammatory effects by differentially modulating dendritic cell differentiation and function. J Cell Physiol 232:1176–1186. https://doi.org/10.1002/JCP.25604

Article  CAS  Google Scholar 

Li N, Zhang X, Dong H et al (2016) Lithium ameliorates LPS-induced astrocytes activation partly via inhibition of Toll-like receptor 4 expression. Cell Physiol Biochem 38:714–725. https://doi.org/10.1159/000443028

Article  CAS  Google Scholar 

Li HJ, Gao DS, Li YT et al (2018) Antiviral effect of lithium chloride on porcine epidemic diarrhea virus in vitro. Res Vet Sci 118:288–294. https://doi.org/10.1016/J.RVSC.2018.03.002

Article  CAS  PubMed Central  Google Scholar 

Lu SM, Gui B, Dong HQ et al (2015) Prophylactic lithium alleviates splenectomy-induced cognitive dysfunction possibly by inhibiting hippocampal TLR4 activation in aged rats. Brain Res Bull 114:31–41. https://doi.org/10.1016/J.BRAINRESBULL.2015.02.008

Article  CAS  Google Scholar 

Mazgaeen L, Gurung P (2020) Recent advances in lipopolysaccharide recognition systems. Int J Mol Sci 21. https://doi.org/10.3390/IJMS21020379

Murru A, Manchia M, Hajek T et al (2020) Lithium’s antiviral effects: a potential drug for COVID-19 disease? Int J Bipolar Disord 8:1–9. https://doi.org/10.1186/S40345-020-00191-4/METRICS

Article  Google Scholar 

Nassar A, Azab AN (2014) Effects of lithium on inflammation. ACS Chem Neurosci 5:451–458. https://doi.org/10.1021/cn500038f

Article  CAS  PubMed Central  Google Scholar 

Nunes A, Trappenberg T, Alda M (2020) Asymmetrical reliability of the Alda score favours a dichotomous representation of lithium responsiveness. PLoS ONE 15:e0225353. https://doi.org/10.1371/JOURNAL.PONE.0225353

Article  CAS  PubMed Central  Google Scholar 

Oliveira J, Busson M, Etain B et al (2014) Polymorphism of Toll-like receptor 4 gene in bipolar disorder. J Affect Disord 152–154:395–402. https://doi.org/10.1016/J.JAD.2013.09.043

Article 

留言 (0)

沒有登入
gif