Adibhatla RM, Hatcher JF, Dempsey RJ (2002) Citicoline: neuroprotective mechanisms in cerebral ischemia. J Neurochem 80:12–23
Agut J, Ortiz JA, Wurtman RJ (2000) Cytidine (5')diphosphocholine modulates dopamine K(+)-evoked release in striatum measured by microdialysis. Ann N Y Acad Sci 920:332–335
Alijanpour S, Khakpai F, Ebrahimi-Ghiri M, Zarrindast MR (2019) Co-administration of the low dose of orexin and nitrergic antagonists induces an antidepressant-like effect in mice. Biomed Pharmacother 109:589–594
Arenth PM, Russell KC, Ricker JH, Zafonte RD (2011) CDP-choline as a biological supplement during neurorecovery: a focused review. PM R 3:S123–S131
Ashton C, Moore P (2011) Endocannabinoid system dysfunction in mood and related disorders. Acta Psychiatr Scand 124:250–261
Babb S, Wald L, Cohen B, Villafuerte R, Gruber S, Yurgelun-Todd D, Renshaw P (2002) Chronic citicoline increases phosphodiesters in the brains of healthy older subjects: an in vivo phosphorus magnetic resonance spectroscopy study. Psychopharmacology 161:248–254
Baer L, Blais MA (2010) Handbook of clinical rating scales and assessment in psychiatry and mental health. Springer
Bahi A, Al Mansouri S, Al Memari E, Al Ameri M, Nurulain SM, Ojha S (2014) β-Caryophyllene, a CB2 receptor agonist produces multiple behavioral changes relevant to anxiety and depression in mice. Physiol Behav 135:119–124
Bright U, Akirav I (2022) Modulation of endocannabinoid system components in depression: pre-clinical and clinical evidence. Int J Mol Sci 23:5526
Article PubMed PubMed Central Google Scholar
Brown ES, Gabrielson B (2012) A randomized, double-blind, placebo-controlled trial of citicoline for bipolar and unipolar depression and methamphetamine dependence. J Affect Disord 143:257–260
Burstein O, Shoshan N, Doron R, Akirav I (2018) Cannabinoids prevent depressive-like symptoms and alterations in BDNF expression in a rat model of PTSD. Prog Neuropsychopharmacol Biol Psychiatry 84:129–139
Chiba S, Numakawa T, Ninomiya M, Richards MC, Wakabayashi C, Kunugi H (2012) Chronic restraint stress causes anxiety- and depression-like behaviors, downregulates glucocorticoid receptor expression, and attenuates glutamate release induced by brain-derived neurotrophic factor in the prefrontal cortex. Prog Neuropsychopharmacol Biol Psychiatry 39:112–119
Christiansen SH, Olesen MV, Wortwein G, Woldbye DP (2011) Fluoxetine reverts chronic restraint stress-induced depression-like behaviour and increases neuropeptide Y and galanin expression in mice. Behav Brain Res 216:585–591
de Kloet ER, Joels M, Holsboer F (2005) Stress and the brain: from adaptation to disease. Nat Rev Neurosci 6:463–475
Emril DR, Wibowo S, Meliala L, Susilowati R (2016) Cytidine 5'-diphosphocholine administration prevents peripheral neuropathic pain after sciatic nerve crush injury in rats. J Pain Res 9:287–291
Article PubMed PubMed Central Google Scholar
Fioravanti M, Buckley AE (2006) Citicoline (Cognizin) in the treatment of cognitive impairment. Clin Interv Aging 1:247–251
Article PubMed PubMed Central Google Scholar
Gallego-Landin I, Garcia-Baos A, Castro-Zavala A, Valverde O (2021) Reviewing the role of the endocannabinoid system in the pathophysiology of depression. Front Pharmacol 12:762738
Article PubMed PubMed Central Google Scholar
Garcia-Cobos R, Frank-Garcia A, Gutierrez-Fernandez M, Diez-Tejedor E (2010) Citicoline, use in cognitive decline: vascular and degenerative. J Neurol Sci 299:188–192
Grizzell JA, Iarkov A, Holmes R, Mori T, Echeverria V (2014) Cotinine reduces depressive-like behavior, working memory deficits, and synaptic loss associated with chronic stress in mice. Behav Brain Res 268:55–65
Hayase T (2016) Putative epigenetic involvement of the endocannabinoid system in anxiety-and depression-related behaviors caused by nicotine as a stressor. PLoS One 11:e0158950
Article PubMed PubMed Central Google Scholar
Herman JP, McKlveen JM, Solomon MB, Carvalho-Netto E, Myers B (2012) Neural regulation of the stress response: glucocorticoid feedback mechanisms. Braz J Med Biol Res 45:292–298
Article PubMed PubMed Central Google Scholar
Huang WJ, Chen WW, Zhang X (2016) Endocannabinoid system: role in depression, reward and pain control (Review). Mol Med Rep 14:2899–2903
Article PubMed PubMed Central Google Scholar
Khakpai F, Ebrahimi-Ghiri M, Alijanpour S, Zarrindast M-R (2019) Ketamine-induced antidepressant like effects in mice: a possible involvement of cannabinoid system. Biomed Pharmacother 112:108717
Khakpai F, Ramezanikhah M, Valizadegan F, Zarrindast M-R (2021) Synergistic effect between imipramine and citicoline upon induction of analgesic and antidepressant effects in mice. Neurosci Lett 760:136095
Khakpai F, Zarrindast MR (2023) The effect of nicotine on antidepressant and anxiolytic responses induced by citalopram and citicoline in mice. Acta Neurobiol Exp 83:194–202
Korem N, Akirav I (2014) Cannabinoids prevent the effects of a footshock followed by situational reminders on emotional processing. Neuropsychopharmacology 39:2709–2722
Article PubMed PubMed Central Google Scholar
Kruk-Slomka M, Michalak A, Biala G (2015) Antidepressant-like effects of the cannabinoid receptor ligands in the forced swimming test in mice: mechanism of action and possible interactions with cholinergic system. Behav Brain Res 284:24–36
Li S, Fan YX, Wang W, Tang YY (2012) Effects of acute restraint stress on different components of memory as assessed by object-recognition and object-location tasks in mice. Behav Brain Res 227:199–207
Licata SC, Penetar DM, Ravichandran C, Rodolico J, Palmer C, Berko J, Geaghan T, Looby A, Peters E, Ryan E (2011) Effects of daily treatment with citicoline: a double-blind, placebo-controlled study in cocaine-dependent volunteers. J Addict Med 5:57
Article PubMed PubMed Central Google Scholar
Micale V, Di Marzo V, Sulcova A, Wotjak CT, Drago F (2013) Endocannabinoid system and mood disorders: priming a target for new therapies. Pharmacol Ther 138:18–37
Mosaffa S, Ahmadi H, Khakpai F, Ebrahimi-Ghiri M, Zarrindast MR (2020) Synergistic antidepressant- and anxiolytic-like effects of harmaline along with cinanserin in acute restraint stress-treated mice. Psychopharmacology (Berl):1–11
Nejati S, Khakpai F, Zarrindast MR (2020) Synergistic effect between citalopram and citicoline on anxiolytic effect in non-sensitized and morphine-sensitized mice: an isobologram analysis. Brain Res 1734:146701
Paxinos G, Franklin KBJ (2001) The mouse brain in stereotaxic coordinates, 2nd edn. Academic Press, San Diego
Poleszak E, Wosko S, Slawinska K, Szopa A, Wrobel A, Serefko A (2018) Cannabinoids in depressive disorders. Life Sci 213:18–24
R Albert P, M Fiori L (2014) Transcriptional dys-regulation in anxiety and major depression: 5-HT1A gene promoter architecture as a therapeutic opportunity. Curr Pharm Design 20:3738–3750
Roohi-Azizi M, Torkaman-Boutorabi A, Akhondzadeh S, Nejatisafa AA, Sadat-Shirazi MS, Zarrindast MR (2018) Influence of citicoline on citalopram-induced antidepressant activity in depressive-like symptoms in male mice. Physiol Behav 195:151–157
Saadati N, Bananej M, Khakpai F, Zarrindast M-R, Alibeik H (2022) Synergistic antidepressant effects of citalopram and SB-334867 in the REM sleep-deprived mice: possible role of BDNF. Pharmacol Biochem Behav 219:173449
Sachs BD, Ni JR, Caron MG (2015) Brain 5-HT deficiency increases stress vulnerability and impairs antidepressant responses following psychosocial stress. Proc Natl Acad Sci 112:2557–2562
Article PubMed PubMed Central Google Scholar
Safavi M, Hosseini-Sharifabad A, Seyed-Yousefi Y, Rabbani M (2020) Protective effects of citicoline and benfotiamine each alone and in combination on streptozotocin-induced memory impairment in mice. Clin Psychopharmacol Neurosci 18:81–92
Article PubMed PubMed Central Google Scholar
Serra G, Fratta W (2007) A possible role for the endocannabinoid system in the neurobiology of depression. Clin Pract Epidemiol Ment Health 3:25
Article PubMed PubMed Central Google Scholar
Shoji H, Miyakawa T (2020) Differential effects of stress exposure via two types of restraint apparatuses on behavior and plasma corticosterone level in inbred male BALB/cAJcl mice. Neuropsychopharmacol Rep 40:73–84
留言 (0)