Anton RF, Moak DH, Latham PK (1996) The Obsessive Compulsive Drinking Scale: A New Method of Assessing Outcome in Alcoholism Treatment Studies. Arch Gen Psychiatry 53:225–231

Article  PubMed  CAS  Google Scholar 

Beck AT, Epstein N, Brown G, Steer RA (1988) An inventory for measuring clinical anxiety: Psychometric properties. J Consult Clin Psychol 56:893–897

Article  PubMed  CAS  Google Scholar 

Beck AT, Steer RA, Brown G (1996) Beck depression inventory–II. Psychological assessment

Biener L, Abrams DB (1991) The Contemplation Ladder: validation of a measure of readiness to consider smoking cessation. Health Psychol 10:360–365

Article  PubMed  CAS  Google Scholar 

Bohn MJ, Krahn DD, Staehler BA (1995) Development and Initial Validation of a Measure of Drinking Urges in Abstinent Alcoholics. Alcohol Clin Exp Res 19:600–606

Article  PubMed  CAS  Google Scholar 

Buysse DJ, Reynolds CF 3rd, Monk TH, Berman SR, Kupfer DJ (1989) The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research. Psychiatry Res 28:193–213

Article  PubMed  CAS  Google Scholar 

Cooney NL, Litt MD, Morse PA, Bauer LO, Gaupp L (1997) Alcohol cue reactivity, negative-mood reactivity, and relapse in treated alcoholic men. J Abnorm Psychol 106:243–250

Article  PubMed  CAS  Google Scholar 

Deci EL, Ryan RM (1985) The general causality orientations scale: self-determination in personality. J Res Pers 19(2):109–134

First MB, Williams JB, Karg RS, Spitzer RL (2015) Structured clinical interview for DSM-5—Research version (SCID-5 for DSM-5, research version; SCID-5-RV). American Psychiatric Association, pp 1–94

Google Scholar 

Flannery BA, Volpicelli JR, Pettinati HM (1999) Psychometric properties of the Penn Alcohol Craving Scale. Alcohol Clin Exp Res 23:1289–1295

Article  PubMed  CAS  Google Scholar 

Grant BF, Goldstein RB, Saha TD, Chou SP, Jung J, Zhang H, Pickering RP, Ruan WJ, Smith SM, Huang B, Hasin DS (2015) Epidemiology of DSM-5 Alcohol Use Disorder: Results From the National Epidemiologic Survey on Alcohol and Related Conditions III. JAMA Psychiatry 72:757–766

Article  PubMed  PubMed Central  Google Scholar 

Grodin EN, Bujarski S, Venegas A, Baskerville W-A, Nieto SJ, Jentsch JD, Ray LA (2019) Reward, Relief and Habit Drinking: Initial Validation of a Brief Assessment Tool. Alcohol Alcohol 54:574–583

Article  PubMed  PubMed Central  CAS  Google Scholar 

Haass-Koffler CL, Magill M, Cannella N, Brown JC, Aoun EG, Cioe PA, Sinha R, Swift RM, Ciccocioppo R, Leggio L (2023) Mifepristone as a pharmacological intervention for stress-induced alcohol craving: A human laboratory study. Addict Biol 28:e13288

Article  PubMed  CAS  Google Scholar 

Heatherton TF, Kozlowski LT, Frecker RC, Ko F (1991) The Fagerström test for nicotine dependence: a revision of the Fagerstrom Tolerance Questionnaire. Br J Addict 86:1119–1127

Article  PubMed  CAS  Google Scholar 

Hendershot CS, Wardell JD, Samokhvalov AV, Rehm J (2017) Effects of naltrexone on alcohol self-administration and craving: meta-analysis of human laboratory studies. Addict Biol 22:1515–1527

Article  PubMed  CAS  Google Scholar 

Ho D, Towns B, Grodin EN, Ray LA (2020) A novel human laboratory model for screening medications for alcohol use disorder. Trials 21:947

Article  PubMed  PubMed Central  Google Scholar 

Jacobson AF, Goldstein BJ, Dominguez RA, Steinbook RM (1986) Interrater agreement and intraclass reliability measures of SAFTEE in psychopharmacologic clinical trials. Psychopharmacol Bull 22:382–388

PubMed  CAS  Google Scholar 

Leggio L, Zywiak WH, McGeary JE, Edwards S, Fricchione SR, Shoaff JR, Addolorato G, Swift RM, Kenna GA (2013) A human laboratory pilot study with baclofen in alcoholic individuals. Pharmacol Biochem Behav 103:784–791

Article  PubMed  CAS  Google Scholar 

Leventhal AM, Cho J, Ray LA, Liccardo Pacula R, Lee BP, Terrault N, Pedersen E, Lee JO, Davis JP, Jin H, Huh J, Wilson JP, Whaley RC (2022) Alcohol use trajectories among U.S. adults during the first 42 weeks of the COVID-19 pandemic. Alcohol Clin Exp Res 46:1062–1072

Article  PubMed  PubMed Central  CAS  Google Scholar 

Levine J, Schooler NR (1986) SAFTEE: a technique for the systematic assessment of side effects in clinical trials. Psychopharmacol Bull 22:343–381

PubMed  CAS  Google Scholar 

Litten RZ, Egli M, Heilig M, Cui C, Fertig JB, Ryan ML, Falk DE, Moss H, Huebner R, Noronha A (2012) Medications development to treat alcohol dependence: a vision for the next decade. Addict Biol 17:513–527

Article  PubMed  PubMed Central  CAS  Google Scholar 

Litten RZ, Falk DE, Ryan ML, Fertig JB (2016) Discovery, Development, and Adoption of Medications to Treat Alcohol Use Disorder: Goals for the Phases of Medications Development. Alcohol Clin Exp Res 40:1368–1379

Article  PubMed  PubMed Central  Google Scholar 

Litten RZ, Ryan ML, Fertig JB, Falk DE, Johnson B, Dunn KE, Green AI, Pettinati HM, Ciraulo DA, Sarid-Segal O, Kampman K, Brunette MF, Strain EC, Tiouririne NA, Ransom J, Scott C, Stout R (2013) A double-blind, placebo-controlled trial assessing the efficacy of varenicline tartrate for alcohol dependence. J Addict Med 7:277–286

Article  PubMed  PubMed Central  CAS  Google Scholar 

MacKillop J, Agabio R, Feldstein Ewing SW, Heilig M, Kelly JF, Leggio L, Lingford-Hughes A, Palmer AA, Parry CD, Ray L, Rehm J (2022) Hazardous drinking and alcohol use disorders. Nat Rev Dis Primers 8:80

Article  PubMed  PubMed Central  Google Scholar 

Meredith LR, Burnette EM, Nieto SJ, Du H, Donato S, Grodin EN, Green R, Magill M, Baskerville WA, Ray LA (2023) Testing pharmacotherapies for alcohol use disorder with cue exposure paradigms: a systematic review and quantitative synthesis of human laboratory trial methodology. Alcohol Clin Exp Res (Hoboken). https://doi.org/10.1111/acer.15143

Miranda R Jr, O'Malley SS, Treloar Padovano H, Wu R, Falk DE, Ryan ML, Fertig JB, Chun TH, Muvvala SB, Litten RZ (2020) Effects of Alcohol Cue Reactivity on Subsequent Treatment Outcomes Among Treatment-Seeking Individuals with Alcohol Use Disorder: A Multisite Randomized, Double-Blind, Placebo-Controlled Clinical Trial of Varenicline. Alcohol Clin Exp Res 44:1431–1443

Article  PubMed  PubMed Central  CAS  Google Scholar 

Monti PM, Binkoff JA, Abrams DB, Zwick WR, Nirenberg TD, Liepman MR (1987) Reactivity of alcoholics and nonalcoholics to drinking cues. J Abnorm Psychol 96:122–126

Article  PubMed  CAS  Google Scholar 

Monti PM, Rohsenow DJ, Swift RM, Gulliver SB, Colby SM, Mueller TI, Brown RA, Gordon A, Abrams DB, Niaura RS, Asher MK (2001) Naltrexone and cue exposure with coping and communication skills training for alcoholics: treatment process and 1-year outcomes. Alcohol Clin Exp Res 25:1634–1647

PubMed  CAS  Google Scholar 

Perkins KA (2012) Subjective reactivity to smoking cues as a predictor of quitting success. Nicotine Tob Res 14:383–387

Article  PubMed  Google Scholar 

Perkins KA (2014) Improving efficiency of initial tests for efficacy in smoking cessation drug discovery. Expert Opin Drug Discovery 9:1259–1264

Article  CAS  Google Scholar 

Perkins KA, Lerman C (2014) An efficient early phase 2 procedure to screen medications for efficacy in smoking cessation. Psychopharmacology (Berl) 231:1–11

Article  PubMed  CAS  Google Scholar 

Perkins KA, Lerman C, Fonte CA, Mercincavage M, Stitzer ML, Chengappa KN, Jain A (2010) Cross-validation of a new procedure for early screening of smoking cessation medications in humans. Clin Pharmacol Ther 88:109–114

Article  PubMed  CAS  Google Scholar 

Perkins KA, Lerman C, Stitzer M, Fonte CA, Briski JL, Scott JA, Chengappa KN (2008) Development of procedures for early screening of smoking cessation medications in humans. Clin Pharmacol Ther 84:216–221

Article  PubMed  CAS  Google Scholar 

Perkins KA, Stitzer M, Lerman C (2006) Medication screening for smoking cessation: a proposal for new methodologies. Psychopharmacology (Berl) 184:628–636

Article  PubMed  CAS  Google Scholar 

Ray LA, Bujarski S, Roche DJO, Magill M (2018) Overcoming the "Valley of Death" in Medications Development for Alcohol Use Disorder. Alcohol Clin Exp Res 42:1612–1622

Article  PubMed  PubMed Central  Google Scholar 

Ray LA, Bujarski S, Yardley MM, Roche DJO, Hartwell EE (2017) Differences between treatment-seeking and non-treatment-seeking participants in medication studies for alcoholism: do they matter? Am J Drug Alcohol Abuse 43:703–710

Article  PubMed  PubMed Central  Google Scholar 

Ray LA, Chin PF, Miotto K (2010a) Naltrexone for the treatment of alcoholism: clinical findings, mechanisms of action, and pharmacogenetics. CNS Neurol Disord Drug Targets 9:13–22

Article  PubMed  CAS  Google Scholar 

Ray LA, Du H, Green R, Roche DJO, Bujarski S (2021) Do behavioral pharmacology findings predict clinical trial outcomes? A proof-of-concept in medication development for alcohol use disorder. Neuropsychopharmacology 46:519–527

Article  PubMed  CAS  Google Scholar