Effects of cabergoline and dimethylcabergoline on the sexual behavior of male rats

Afonso VM, Mueller D, Stewart J, Pfaus JG (2009) Amphetamine pretreatment facilitates appetitive sexual behaviors in the female rat. Psychopharmacology 205:35–43

Article  CAS  PubMed  Google Scholar 

Ahlenius S, Engel J, Larsson K, Svensson L (1982) Effects of pergolide and bromocriptine on male rat sexual behavior. J Neural Transm 54:165–170

Article  CAS  PubMed  Google Scholar 

Allers KA, Dremencov E, Ceci A, Flik G, Ferger B, Cremers TI, Ittrich C, Sommer B (2010) Acute and repeated flibanserin administration in female rats modulates monoamines differentially across brain areas: a microdialysis study. J Sex Med 7:1757–1767

Article  CAS  PubMed  Google Scholar 

Antonini A, Poewe W (2007) Fibrotic heart-valve reactions to dopamine-agonist treatment in Parkinson’s disease. Lancet Neurol 6:826–829

Article  CAS  PubMed  Google Scholar 

Arnow BA, Millheiser L, Garrett A, Lake Polan M, Glover GH, Hill KR, Lightbody A, Watson C, Banner L, Smart T, Buchanan T, Desmond JE (2009) Women with hypoactive sexual desire disorder compared to normal females: a functional magnetic resonance imaging study. Neuroscience 158:484–502

Article  CAS  PubMed  Google Scholar 

Baum MJ, Everitt BJ (1992) Increased expression of c-fos in the medial preoptic area after mating in male rats: role of afferent inputs from the medial amygdala and midbrain central tegmental field. Neuroscience 50:627–646

Article  CAS  PubMed  Google Scholar 

Berg KA, Harvey JA, Spampinato U, Clarke WP (2008) Physiological and therapeutic relevance of constitutive activity of 5-HT 2A and 5-HT 2C receptors for the treatment of depression. Prog Brain Res 172:287–305

Article  CAS  PubMed  Google Scholar 

Bhattacharyya S, Schapira AH, Mikhailidis DP, Davar J (2009) Drug-induced fibrotic valvular heart disease. Lancet 374:577–585

Article  CAS  PubMed  Google Scholar 

Bitran D, Thompson JT, Hull EM, Sachs BD (1989) Quinelorane (LY163502), a D2 dopamine receptor agonist, facilitates seminal emission, but inhibits penile erection in the rat. Pharmacol Biochem Behav 34:453–458

Article  CAS  PubMed  Google Scholar 

Blackburn JR, Pfaus JG, Phillips AG (1992) Dopamine functions in appetitive and defensive behaviours. Prog Neurobiol 39:247–279

Article  CAS  PubMed  Google Scholar 

Buvat J (2003) Hyperprolactinemia and sexual function in men: a short review. Int J Impot Res 15:373–377

Article  CAS  PubMed  Google Scholar 

Cabilio S (1996) Behavioral scoring program Unpublished software. Concordia University, Montréal

Google Scholar 

Cantor JM, Binik YM, Pfaus JG (1999) Chronic fluoxetine inhibits sexual behavior in the male rat: reversal with oxytocin. Psychopharmacology 144:355–362

Article  CAS  PubMed  Google Scholar 

Colao A, di Sarno A, Pivonello R, di Somma C, Lombardi G (2002) Dopamine receptor agonists for treating prolactinomas. Expert Opin Investig Drugs 11:787–800

Article  CAS  PubMed  Google Scholar 

Coolen LM, Peters HJ, Veening JG (1998) Anatomical interrelationships of the medial preoptic area and other brain regions activated following male sexual behavior: a combined fos and tract-tracing study. J Comp Neurol 397:421–435

Article  CAS  PubMed  Google Scholar 

Corona G, Rastrelli G, Bianchi N, Sparano C, Sforza A, Vignozzi L, Maggi M (2023) Hyperprolactinemia and male sexual function: focus on erectile dysfunction and sexual desire. Int J Impot Res. https://doi.org/10.1038/s41443-023-00717-1

Article  PubMed  Google Scholar 

Cosyns B, Droogmans S, Rosenhek R, Lancellotti P (2013) Drug-induced valvular heart disease. Heart 99:7–12

Article  PubMed  Google Scholar 

Dalló J, Lekka N, Knoll J (1986) The ejaculatory behavior of sexually sluggish male rats treated with (-)deprenyl, apomorphine, bromocriptine and amphetamine. Pol J Pharmacol Pharm 38:251–255

PubMed  Google Scholar 

Deebel NA, Thai K, Ramasamy R, Terlecki RP (2022) Understanding the dopaminergic pathway relative to men’s sexual dysfunction in patients with Parkinson’s disease: a narrative review with implications for future research. Int J Impot Res. https://doi.org/10.1038/s41443-022-00656-3

Article  PubMed  Google Scholar 

Devroye C, Cathala A, Di Marco B, Caraci F, Drago F, Piazza PV, Spampinato U (2015) Central serotonin(2B) receptor blockade inhibits cocaine-induced hyperlocomotion independently of changes of subcortical dopamine outflow. Neuropharmacology 97:329–337

Article  CAS  PubMed  Google Scholar 

Doherty PC, Bartke A, Smith MS (1981) Differential effects of bromocriptine treatment on LH release and copulatory behavior in hyperprolactinemic male rats. Horm Behav 15:436–450

Article  CAS  PubMed  Google Scholar 

Dosa PI, Ward T, Walters MA, Kim SW (2013) Synthesis of novel analogs of cabergoline: improving cardiovascular safety by removing 5-HT2B receptor agonism. ACS Med Chem Lett 4:254–258

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ferrara N, Bernardini R, Nicoletti F, Drago F, Matera M, Ceravolo A, Scapagnini U (1985) Prolactin influences sexual behavior during aging. J Endocrinol Invest 8(Suppl 2):23–32

PubMed  Google Scholar 

Fitzgerald LW, Burn TC, Brown BS, Patterson JP, Corjay MH, Valentine PA, Sun JH, Link JR, Abbaszade I, Hollis JM, Largent BL, Hartig PR, Hollis GF, Meunier PC, Robichaud AJ, Robertson DW (2000) Possible role of valvular serotonin 5-HT(2B) receptors in the cardiopathy associated with fenfluramine. Mol Pharmacol 57:75–81

CAS  PubMed  Google Scholar 

Gebeyehu NA, Gesese MM, Tegegne KD, Kebede YS, Kassie GA, Mengstie MA, Zemene MA, Bantie B, Feleke SF, Dejenie TA, Abebe EC, Anley DT, Dessie AM, Bayih WA, Adela GA (2023) Global prevalence of sexual dysfunction among diabetic patients from 2008 to 2022: systematic review and meta-analysis. Metabol Open 18:100247

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gelez H, Clement P, Compagnie S, Gorny D, Laurin M, Allers K, Sommer B, Giuliano F (2013) Brain neuronal activation induced by flibanserin treatment in female rats. Psychopharmacology 230:639–652

Article  CAS  PubMed  Google Scholar 

Giuliano F, Rampin O (2004) Neural control of erection. Physiol Behav 83:189–201

Article  CAS  PubMed  Google Scholar 

González Cautela BV, Quintana GR, Akerman J, Pfaus JG (2021) Acute caffeine reverses the disruptive effects of chronic fluoxetine on the sexual behavior of female and male rats. Psychopharmacology 238:755–764

Article  PubMed  Google Scholar 

Graham MD, Pfaus JG (2012) Differential effects of dopamine antagonists infused to the medial preoptic area on the sexual behavior of female rats primed with estrogen and progesterone. Pharmacol Biochem Behav 102:532–539

Article  CAS  PubMed  Google Scholar 

Graham MD, Gardner Gregory J, Hussain D, Brake WG, Pfaus JG (2015) Ovarian steroids alter dopamine receptor populations in the medial preoptic area of female rats: implications for sexual motivation, desire, and behaviour. Eur J Neurosci 42:3138–3148

Article  PubMed  Google Scholar 

Harding SM, McGinnis MY (2005) Microlesions of the ventromedial nucleus of the hypothalamus: effects on sociosexual behaviors in male rats. Behav Neurosci 119:1227–1234

Article  PubMed  Google Scholar 

Harding SM, McGinnis MY (2004) Androgen receptor blockade in the MPOA or VMN: effects on male sociosexual behaviors. Physiol Behav 81:671–680

Article  CAS  PubMed  Google Scholar 

Hollander AB, Pastuszak AW, Hsieh TC, Johnson WG, Scovell JM, Mai CK, Lipshultz LI (2016) Cabergoline in the treatment of male orgasmic disorder - a retrospective pilot analysis. Sex Med 4:e28–e33

Article  PubMed  PubMed Central  Google Scholar 

Holt RI, Barnett AH, Bailey CJ (2010) Bromocriptine: old drug, new formulation and new indication. Diabetes Obes Metab 12:1048–1057

Article  CAS  PubMed  Google Scholar 

Horvath J, Fross RD, Kleiner-Fisman G, Lerch R, Stalder H, Liaudat S, Raskoff WJ, Flachsbart KD, Rakowski H, Pache JC, Burkhard PR, Lang AE (2004) Severe multivalvular heart disease: a new complication of the ergot derivative dopamine agonists. Mov Disord 19:656–662

Article  PubMed  Google Scholar 

Hull EM, Dominguez JM (2007) Sexual behavior in male rodents. Horm Behav 52:45–55

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ismail N, Laroche C, Girard-Bériault F, Ménard S, Greggain-Mohr JA, Pfaus JG (2010) Conditioned ejaculatory preference in male rats paired with haloperidol-treated females. Physiol Behav 100:116–121

Article  CAS  PubMed  Google Scholar 

Kippin TE, Cain SW, Pfaus JG (2003) Estrous odors and sexually-conditioned neutr

留言 (0)

沒有登入
gif