Adams M. D., Celniker S. E., Holt R. A., Evans C. A., Gocayne J. D., Amanatides P. G. et al. 2000 The genome sequence of Drosophila melanogaster. Science 287, 2185–2195.

Article  PubMed  Google Scholar 

Brand A. H. and Perrimon N. 1993 Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118, 401–415.

Article  CAS  PubMed  Google Scholar 

Brembs B., Christiansen F., Pflüger H. J. and Duch C. 2007 Flight initiation and maintenance deficits in flies with genetically altered biogenic amine levels. J. Neurosci. 27, 11122–11131.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Busch S., Selcho M., Ito K. and Tanimoto H. 2009 A map of octopaminergic neurons in the Drosophila brain. J. Comp. Neurol. 513, 643–667.

Article  PubMed  Google Scholar 

Certel S. J., Savella M. G., Schlegel D. C. and Kravitz E. A. 2007 Modulation of Drosophila male behavioral choice. Proc. Natl. Acad. Sci. USA 104, 4706–4711.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cole S. H., Carney G. E., McClung C. A., Willard S. S., Taylor B. J. and Hirsh J. 2005 Two functional but noncomplementing Drosophila tyrosine decarboxylase genes: distinct roles for neural tyramine and octopamine in female fertility. J. Biol. Chem. 280, 14948–14955.

Article  CAS  PubMed  Google Scholar 

Crocker A. and Sehgal A. 2008 Octopamine regulates sleep in Drosophila through protein kinase A-dependent mechanisms. J. Neurosci. 28, 9377–9385.

Article  CAS  PubMed  PubMed Central  Google Scholar 

El-Kholy S. E., Afifi B., El-Husseiny I. and Seif A. 2022 Octopamine signaling via OctαR is essential for a well-orchestrated climbing performance of adult Drosophila melanogaster. Sci. Rep. 12, 14024.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Evans P. D. O. 1985 In Comprehensive insect physiology, biochemistry and pharmacology (ed. G. A. Kerkut and L. I. Gilbert), pp. 499–530. Pergamon, Oxford.

Feany M. B. and Bender W. W. 2000 A Drosophila model of Parkinson’s disease. Nature 404, 394–398.

Article  CAS  PubMed  Google Scholar 

Fox L. E., Soll D. R. and Wu C. F. 2006 Coordination and modulation of locomotion pattern generators in Drosophila larvae: effects of altered biogenic amine levels by the tyramine β hydroxylase mutation. J. Neurosci. 26, 1486–1498.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gaudet P., Livstone M. S., Lewis S. E. and Thomas P. D. 2011 Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinform. 12, 449–462.

Article  PubMed  PubMed Central  Google Scholar 

Hoyer S. C., Eckart A., Herrel A., Zars T., Fischer S. A., Hardie S. L. and Heisenberg M. 2008 Octopamine in male aggression of Drosophila. Curr. Biol. 18, 159–167.

Article  CAS  PubMed  Google Scholar 

Hu Y., Flockhart I., Vinayagam A., Bergwitz C., Berger B., Perrimon N. et al. 2011 An integrative approach to ortholog prediction for disease-focused and other functional studies. BMC Bioinform. 12, 1–16.

Article  CAS  Google Scholar 

Iliadi K. G., Iliadi N. and Boulianne G. L. 2017 Drosophila mutants lacking octopamine exhibit impairment in aversive olfactory associative learning. Eur. J. Neurosci. 46, 2080–2087.

Article  PubMed  Google Scholar 

Ito K., Shinomiya K., Ito M., Armstrong J. D., Boyan G., Hartenstein V. et al. 2014 A systematic nomenclature for the insect brain. Neuron 81, 755–765.

Article  CAS  PubMed  Google Scholar 

Kasture A. S., Hummel T., Sucic S. and Freissmuth M. 2018 Big lessons from tiny flies: Drosophila melanogaster as a model to explore dysfunction of dopaminergic and serotonergic neurotransmitter systems. Int. J. Mol. Sci. 19, 1788.

Article  PubMed  PubMed Central  Google Scholar 

Lee P. T., Zirin J., Kanca O., Lin W. W., Schulze K. L., Li-Kroeger D. et al. 2018 A gene-specific T2A-GAL4 library for Drosophila. Elife. 7, e35574.

Article  PubMed  PubMed Central  Google Scholar 

Livingstone M. S. and Tempel B. L. 1983 Genetic dissection of monoamine neurotransmitter synthesis in Drosophila. Nature 303, 67–70.

Article  CAS  PubMed  Google Scholar 

Mao Z. and Davis R. L. 2009 Eight different types of dopaminergic neurons innervate the Drosophila mushroom body neuropil: anatomical and physiological heterogeneity. Front. Neural Circuits 3, 612.

Article  Google Scholar 

Monastirioti M., Gorczyca M., Rapus J., Eckert M., White K. and Budnik V. 1995 Octopamine immunoreactivity in the fruit fly Drosophila melanogaster. J. Comp. Neurol. 356, 275–287.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Otsuna H. and Ito K. 2006 Systematic analysis of the visual projection neurons of Drosophila melanogaster I. Lobula-specific pathways. J. Comp. Neurol. 497, 928–958.

Article  PubMed  Google Scholar 

Perkins L. A., Holderbaum L., Tao R., Hu Y., Sopko R., McCall K. et al. 2015 The transgenic RNAi project at Harvard Medical School: resources and validation. Genetics 201, 843–852.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Rajashekhar K. P. and Shamprasad V. R. 2004 Golgi analysis of tangential neurons in the lobula plate of Drosophila melanogaster. J. Biosci. 29, 93–104.

Article  CAS  PubMed  Google Scholar 

Selcho M., Pauls D., El Jundi B., Stocker R. F. and Thum A. S. 2012 The role of octopamine and tyramine in Drosophila larval locomotion. J. Comp. Neurol. 520, 3764–3785.

Article  CAS  PubMed  Google Scholar 

Shyamala B. V. and Chopra A. 1999 Drosophila melanogaster chemosensory and muscle development: Identification and properties of a novel allele of scalloped and of a new locus, SG18.1, in a Gal4 enhancer trap screen. J. Genet. 78, 87–97.

Article  CAS  Google Scholar 

Sinakevitch I. and Strausfeld N. J. 2006 Comparison of octopamine-like immunoreactivity in the brains of the fruit fly and blow fly. J. Comp. Neurol. 494, 460–475.

Article  CAS  PubMed  Google Scholar 

Tanaka N. K., Tanimoto H. and Ito K. 2008 Neuronal assemblies of the Drosophila mushroom body. J. Comp. Neurol. 508, 711–755.

Article  PubMed  Google Scholar 

Venkatesh C. R. and Shyamala B. V. 2010 GAL4 enhancer trap strains with reporter gene expression during the development of adult brain in Drosophila melanogaster. J. Genet. 89, e38–e42.

Article  CAS  PubMed  Google Scholar 

Wallace B. G. 1976 The biosynthesis of octopamine–characterization of lobster tyramine beta-hydroxylase. J. Neurochem. 26, 761–770.

Article  CAS  PubMed  Google Scholar